Slc9a5 (solute carrier family 9 member A5) - Rat Genome Database

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Gene: Slc9a5 (solute carrier family 9 member A5) Rattus norvegicus
Analyze
Symbol: Slc9a5
Name: solute carrier family 9 member A5
RGD ID: 620473
Description: Enables sodium:proton antiporter activity. Involved in proton transmembrane transport and sodium ion transmembrane transport. Predicted to be located in several cellular components, including focal adhesion; neuron spine; and recycling endosome membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in end stage renal disease. Orthologous to human SLC9A5 (solute carrier family 9 member A5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: na(+)/H(+) exchanger 5; NHE-5; Nhe5; sodium/hydrogen exchanger 5; solute carrier family 9 (sodium/hydrogen exchanger), isoform 5; solute carrier family 9 (sodium/hydrogen exchanger), member 5; solute carrier family 9 member 5; solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21933,225,481 - 33,246,913 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,226,816 - 33,246,903 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1940,042,419 - 40,062,506 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01940,695,745 - 40,715,832 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01942,984,735 - 43,004,818 (+)NCBIRnor_WKY
Rnor_6.01937,304,034 - 37,325,345 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,305,248 - 37,325,335 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01948,169,385 - 48,190,757 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41935,164,590 - 35,184,677 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11935,169,470 - 35,189,558 (+)NCBI
Celera1932,655,246 - 32,675,354 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cellular_component  (ND)
focal adhesion  (IEA,ISO,ISS)
neuron spine  (IEA,ISO,ISS)
plasma membrane  (IBA,IEA,ISO,ISS)
recycling endosome membrane  (IEA,ISO,ISS)
synapse  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Molecular cloning and functional expression of a rat Na+/H+ exchanger (NHE5) highly expressed in brain. Attaphitaya S, etal., J Biol Chem 1999 Feb 12;274(7):4383-8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Human Na+/H+ exchanger genes : identification of polymorphisms by radiation hybrid mapping and analysis of linkage in end-stage renal disease. Yu H, etal., Hypertension. 2000 Jan;35(1 Pt 1):135-43.
Additional References at PubMed
PMID:19248819   PMID:24006492   PMID:26700318  


Genomics

Comparative Map Data
Slc9a5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21933,225,481 - 33,246,913 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,226,816 - 33,246,903 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1940,042,419 - 40,062,506 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01940,695,745 - 40,715,832 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01942,984,735 - 43,004,818 (+)NCBIRnor_WKY
Rnor_6.01937,304,034 - 37,325,345 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,305,248 - 37,325,335 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01948,169,385 - 48,190,757 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41935,164,590 - 35,184,677 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11935,169,470 - 35,189,558 (+)NCBI
Celera1932,655,246 - 32,675,354 (+)NCBICelera
Cytogenetic Map19q12NCBI
SLC9A5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381667,248,979 - 67,272,191 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1667,237,683 - 67,272,191 (+)EnsemblGRCh38hg38GRCh38
GRCh371667,282,882 - 67,306,094 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361665,840,356 - 65,863,595 (+)NCBINCBI36Build 36hg18NCBI36
Build 341665,840,353 - 65,863,594NCBI
Celera1651,791,089 - 51,814,319 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1653,155,929 - 53,179,176 (+)NCBIHuRef
CHM1_11668,690,183 - 68,713,453 (+)NCBICHM1_1
T2T-CHM13v2.01673,043,264 - 73,066,486 (+)NCBIT2T-CHM13v2.0
Slc9a5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398106,074,782 - 106,096,513 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8106,075,475 - 106,096,513 (+)EnsemblGRCm39 Ensembl
GRCm388105,348,156 - 105,369,881 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,348,843 - 105,369,881 (+)EnsemblGRCm38mm10GRCm38
MGSCv378107,872,158 - 107,893,781 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368108,237,387 - 108,259,010 (+)NCBIMGSCv36mm8
Celera8109,571,406 - 109,593,028 (+)NCBICelera
Cytogenetic Map8D3NCBI
Slc9a5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554849,359,468 - 9,379,697 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554849,359,468 - 9,379,959 (-)NCBIChiLan1.0ChiLan1.0
SLC9A5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11666,983,416 - 67,006,938 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1666,983,611 - 67,005,957 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01647,582,950 - 47,617,710 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SLC9A5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1582,103,153 - 82,128,179 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl582,108,097 - 82,128,124 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha582,092,926 - 82,117,670 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0582,538,580 - 82,563,342 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl582,543,783 - 82,563,341 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1582,364,683 - 82,389,439 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0582,050,260 - 82,074,993 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0582,689,504 - 82,714,260 (-)NCBIUU_Cfam_GSD_1.0
Slc9a5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934941,856,418 - 41,878,851 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647517,711,442 - 17,732,658 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493647517,711,025 - 17,732,696 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC9A5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl627,884,592 - 27,904,075 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1627,883,163 - 27,904,076 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2625,150,465 - 25,171,356 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC9A5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1560,181,229 - 60,207,913 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl560,182,190 - 60,206,523 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604722,934,265 - 22,960,155 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc9a5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474619,051,515 - 19,074,076 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474619,051,508 - 19,074,103 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc9a5
72 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:199
Count of miRNA genes:139
Interacting mature miRNAs:165
Transcripts:ENSRNOT00000068299
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)192481797839654489Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)192753020737947399Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)192753020737947399Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)192753020737947399Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 2 2 66 14 20
Low 3 28 24 8 19 8 5 8 8 13 16 11 5
Below cutoff 15 27 27 27 3 3 8 5 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000068299   ⟹   ENSRNOP00000063061
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1933,226,816 - 33,246,903 (+)Ensembl
Rnor_6.0 Ensembl1937,305,248 - 37,325,335 (+)Ensembl
RefSeq Acc Id: NM_138858   ⟹   NP_620213
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21933,226,816 - 33,246,903 (+)NCBI
Rnor_6.01937,305,248 - 37,325,335 (+)NCBI
Rnor_5.01948,169,385 - 48,190,757 (+)NCBI
RGSC_v3.41935,164,590 - 35,184,677 (+)RGD
Celera1932,655,246 - 32,675,354 (+)RGD
Sequence:
RefSeq Acc Id: XM_017601171   ⟹   XP_017456660
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21933,225,481 - 33,246,909 (+)NCBI
Rnor_6.01937,304,034 - 37,325,345 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097458   ⟹   XP_038953386
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21933,226,906 - 33,246,913 (+)NCBI
RefSeq Acc Id: XM_039097459   ⟹   XP_038953387
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21933,225,481 - 33,241,742 (+)NCBI
RefSeq Acc Id: XM_039097460   ⟹   XP_038953388
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21933,225,481 - 33,241,350 (+)NCBI
RefSeq Acc Id: XM_039097461   ⟹   XP_038953389
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21933,232,889 - 33,246,913 (+)NCBI
RefSeq Acc Id: XR_005496609
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21933,225,481 - 33,245,027 (+)NCBI
RefSeq Acc Id: XR_005496610
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21933,225,481 - 33,242,649 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_620213   ⟸   NM_138858
- Peptide Label: precursor
- UniProtKB: Q9Z0X2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017456660   ⟸   XM_017601171
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000063061   ⟸   ENSRNOT00000068299
RefSeq Acc Id: XP_038953387   ⟸   XM_039097459
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038953388   ⟸   XM_039097460
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038953386   ⟸   XM_039097458
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038953389   ⟸   XM_039097461
- Peptide Label: isoform X5
Protein Domains
Na_H_Exchanger

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z0X2-F1-model_v2 AlphaFold Q9Z0X2 1-898 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701075
Promoter ID:EPDNEW_R11598
Type:single initiation site
Name:Slc9a5_1
Description:solute carrier family 9 member A5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01937,305,206 - 37,305,266EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620473 AgrOrtholog
BioCyc Gene G2FUF-5834 BioCyc
Ensembl Genes ENSRNOG00000028844 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000063061 ENTREZGENE
  ENSRNOP00000063061.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000068299 ENTREZGENE
  ENSRNOT00000068299.2 UniProtKB/TrEMBL
InterPro Cation/H_exchanger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cation/H_exchanger_CPA1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na/H_exchanger_3/5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NaH_exchanger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:192215 UniProtKB/Swiss-Prot
NCBI Gene 192215 ENTREZGENE
PANTHER PTHR10110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Na_H_Exchanger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc9a5 PhenoGen
PRINTS NAHEXCHNGR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAHEXCHNGR3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs b_cpa1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt G3V9Y4_RAT UniProtKB/TrEMBL
  Q9Z0X2 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-01 Slc9a5  solute carrier family 9 member A5  Slc9a5  solute carrier family 9 member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-24 Slc9a5  solute carrier family 9 member 5  Slc9a5  solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-16 Slc9a5  solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5  Slc9a5  solute carrier family 9 (sodium/hydrogen exchanger), member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Slc9a5  solute carrier family 9 (sodium/hydrogen exchanger), member 5    solute carrier family 9 (sodium/hydrogen exchanger), isoform 5  Name updated 1299863 APPROVED
2004-09-10 Slc9a5  solute carrier family 9 (sodium/hydrogen exchanger), isoform 5      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Slc9a5  solute carrier family 9 (sodium/hydrogen exchanger), isoform 5      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains has 11-13 transmembrane domains 634199
gene_expression mRNA expressed in the hippocampus and cerebral cortex 634199
gene_protein protein is 898 amino acids 634199