Il27ra (interleukin 27 receptor subunit alpha)

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Gene: Il27ra (interleukin 27 receptor subunit alpha) Rattus norvegicus

Analyze

Symbol:

Il27ra

Name:

interleukin 27 receptor subunit alpha

RGD ID:

1305029

Description:

Predicted to enable cytokine binding activity and interleukin-27 receptor activity. Predicted to contribute to interleukin-12 receptor binding activity and interleukin-23 binding activity. Predicted to be involved in several processes, including negative regulation of T-helper 17 type immune response; negative regulation of cytokine production; and positive regulation of activated T cell proliferation. Predicted to act upstream of or within several processes, including defense response to Gram-positive bacterium; positive regulation of interferon-gamma production; and regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. Predicted to be part of interleukin-12 receptor complex and interleukin-23 receptor complex. Predicted to be active in external side of plasma membrane. Orthologous to human IL27RA (interleukin 27 receptor subunit alpha); PARTICIPATES IN interleukin-27 signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; amphetamine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; LOC288905

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	19	24,109,698 - 24,121,977 (+)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	19	24,109,972 - 24,121,938 (+)	Ensembl
Rnor_6.0	19	25,151,835 - 25,163,995 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	25,149,897 - 25,164,086 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	36,128,834 - 36,140,875 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	25,795,355 - 25,807,317 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	19	25,802,500 - 25,806,104 (+)	NCBI
Celera	19	23,657,895 - 23,669,746 (+)	NCBI		Celera
Cytogenetic Map	19	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asthma (ISO)

pneumoconiosis (ISO)

pulmonary tuberculosis (ISO)

rhinitis (ISO)

systemic scleroderma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

5-aza-2'-deoxycytidine (ISO)

5-fluorouracil (ISO)

8-Br-cAMP (ISO)

actinomycin D (ISO)

aflatoxin B1 (ISO)

amphetamine (EXP)

antirheumatic drug (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

buta-1,3-diene (ISO)

cadmium atom (ISO)

carbamazepine (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

dimethylarsinic acid (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

gentamycin (EXP)

isoflavones (ISO)

lamivudine (ISO)

methylarsonic acid (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-acetyl-L-cysteine (ISO)

N-Nitrosopyrrolidine (ISO)

nickel atom (ISO)

panobinostat (ISO)

perfluorooctanoic acid (ISO)

phytoestrogen (ISO)

potassium chromate (ISO)

resveratrol (ISO)

sarin (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

testosterone (EXP)

thimerosal (ISO)

trichostatin A (ISO)

triclosan (ISO)

triptonide (ISO)

valproic acid (ISO)

zidovudine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

cytokine-mediated signaling pathway (IBA)

defense response to Gram-positive bacterium (ISO)

interleukin-27-mediated signaling pathway (IEA,ISO)

negative regulation of cellular extravasation (ISO)

negative regulation of cytokine-mediated signaling pathway (IBA)

negative regulation of interleukin-17 production (ISO)

negative regulation of interleukin-6 production (ISO)

negative regulation of neuron apoptotic process (ISO)

negative regulation of T cell extravasation (ISO)

negative regulation of T-helper 17 type immune response (ISO)

negative regulation of tumor necrosis factor production (ISO)

negative regulation of type 2 immune response (ISO)

positive regulation of activated T cell proliferation (IBA)

positive regulation of interferon-gamma production (ISO)

positive regulation of T-helper 1 type immune response (ISO)

regulation of isotype switching to IgG isotypes (ISO)

response to lipopolysaccharide (IBA)

Toll signaling pathway (IBA)

Cellular Component

cellular_component (ND)

external side of plasma membrane (IBA)

interleukin-12 receptor complex (IBA)

interleukin-23 receptor complex (IBA)

receptor complex (IBA)

Molecular Function

cytokine binding (IBA)

cytokine receptor activity (IBA)

interleukin-12 receptor binding (IBA)

interleukin-23 binding (IBA)

interleukin-27 receptor activity (IBA,ISO)

molecular_function (ND)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

interleukin-27 signaling pathway (ISO)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Holscher C, etal., J Immunol. 2005 Mar 15;174(6):3534-44.
3.	MGD data from the GO Consortium
4.	Miyazaki Y, etal., J Immunol. 2005 Aug 15;175(4):2401-7.
5.	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	RGD automated import pipeline for gene-chemical interactions
8.	RGD comprehensive gene curation
9.	Shimanoe Y, etal., Ann Allergy Asthma Immunol. 2009 Mar;102(3):223-32.
10.	Yoshizaki A, etal., Ann Rheum Dis. 2011 Jan;70(1):194-200. Epub 2010 Aug 12.

Additional References at PubMed

PMID:11057672	PMID:12121660	PMID:22927332

Genomics

Comparative Map Data

Il27ra
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	19	24,109,698 - 24,121,977 (+)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	19	24,109,972 - 24,121,938 (+)	Ensembl
Rnor_6.0	19	25,151,835 - 25,163,995 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	25,149,897 - 25,164,086 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	36,128,834 - 36,140,875 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	25,795,355 - 25,807,317 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	19	25,802,500 - 25,806,104 (+)	NCBI
Celera	19	23,657,895 - 23,669,746 (+)	NCBI		Celera
Cytogenetic Map	19	q11	NCBI

IL27RA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	14,031,762 - 14,053,218 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	19	14,031,762 - 14,053,218 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	14,142,574 - 14,164,030 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	14,003,262 - 14,025,026 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	19	14,003,261 - 14,025,026	NCBI
Celera	19	14,036,058 - 14,057,825 (+)	NCBI
Cytogenetic Map	19	p13.12	NCBI
HuRef	19	13,714,538 - 13,735,786 (+)	NCBI		HuRef
CHM1_1	19	14,143,096 - 14,164,322 (+)	NCBI		CHM1_1

Il27ra
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	84,756,915 - 84,769,250 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	8	84,756,923 - 84,769,218 (-)	Ensembl
GRCm38	8	84,030,286 - 84,042,600 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	84,030,294 - 84,042,589 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	86,554,185 - 86,566,474 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	8	86,920,423 - 86,932,680 (-)	NCBI			mm8
Celera	8	88,323,361 - 88,337,096 (-)	NCBI		Celera
Cytogenetic Map	8	C2	NCBI

Il27ra
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	32,749,094 - 32,761,882 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	32,749,682 - 32,762,532 (+)	NCBI	ChiLan1.0	ChiLan1.0

IL27RA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	19	14,323,618 - 14,343,636 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	14,323,618 - 14,343,627 (+)	Ensembl	panpan1.1		panPan2

IL27RA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	48,456,766 - 48,475,414 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	48,457,134 - 48,472,450 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	48,330,953 - 48,346,665 (-)	NCBI
ROS_Cfam_1.0	20	48,974,444 - 48,990,172 (-)	NCBI
ROS_Cfam_1.0 Ensembl	20	48,974,445 - 48,990,429 (-)	Ensembl
UMICH_Zoey_3.1	20	48,185,368 - 48,201,224 (-)	NCBI
UNSW_CanFamBas_1.0	20	48,612,194 - 48,627,913 (-)	NCBI
UU_Cfam_GSD_1.0	20	48,854,767 - 48,870,725 (-)	NCBI

Il27ra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	207,634,220 - 207,649,537 (-)	NCBI
SpeTri2.0	NW_004936659	2,706,037 - 2,720,486 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IL27RA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	65,127,278 - 65,149,764 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	65,127,278 - 65,149,665 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	65,401,420 - 65,423,808 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IL27RA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	12,679,270 - 12,699,254 (+)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	6	12,686,838 - 12,701,867 (+)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666074	6,950,555 - 6,971,183 (-)	NCBI	Vero_WHO_p1.0

Il27ra
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624901	1,274,753 - 1,288,783 (+)	NCBI	HetGla_female_1.0		hetGla2

Position Markers

D19Mgh1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
RGSC_v3.4	19	25,801,630 - 25,801,739	UniSTS	RGSC3.4
RGSC_v3.4	19	25,801,629 - 25,801,740	RGD	RGSC3.4
RGSC_v3.4	19	25,801,630 - 25,801,740	UniSTS	RGSC3.4
RGSC_v3.1	19	25,806,455 - 25,806,566	RGD
Celera	19	23,664,170 - 23,664,279	UniSTS
Celera	19	23,664,170 - 23,664,280	UniSTS
SHRSP x BN Map	19	16.9499	RGD
FHH x ACI Map	19	21.16	RGD
Cytogenetic Map	19		RGD

D19Mgh1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	19	36,134,451 - 36,134,560	UniSTS	Rnor5.0
RGSC_v3.4	19	25,801,630 - 25,801,739	UniSTS	RGSC3.4
Celera	19	23,664,170 - 23,664,279	UniSTS
SHRSP x BN Map	19	16.9499	UniSTS
Cytogenetic Map	19	q11	UniSTS

D19Mgh1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	19	36,134,450 - 36,134,560	UniSTS	Rnor5.0
RGSC_v3.4	19	25,801,630 - 25,801,740	UniSTS	RGSC3.4
Celera	19	23,664,170 - 23,664,280	UniSTS
Cytogenetic Map	19	q11	UniSTS

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61447	Tcas1	Tongue tumor susceptibility QTL 1	6.08		tongue integrity trait (VT:0010553)	squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)	19	2316121	47316121	Rat
724518	Uae19	Urinary albumin excretion QTL 19	5.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	7457249	42983518	Rat
724565	Tcas5	Tongue tumor susceptibility QTL 5	10.04		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	19	9977753	39654489	Rat
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2187927	56457239	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	4096155	55283277	Rat
631678	Cm9	Cardiac mass QTL 9	4.27	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	19	1	28982497	Rat
631681	Cm12	Cardiac mass QTL 12	3.33	0.00053	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	19	1	28982497	Rat
1331788	Rf45	Renal function QTL 45	2.818		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	19	15605023	46559041	Rat
2298478	Eau8	Experimental allergic uveoretinitis QTL 8		0.0163	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	19	17154433	57337602	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	15630201	57337602	Rat
1558656	Prcs1	Prostate cancer susceptibility QTL 1	5		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	19	15114598	34521833	Rat
1549847	Bss8	Bone structure and strength QTL 8	4		lumbar vertebra strength trait (VT:0010574)	vertebra ultimate force (CMO:0001678)	19	1	31963836	Rat
2317848	Alcrsp21	Alcohol response QTL 21	1.899999976158142	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	19	3204777	48204777	Rat
61350	Bp32	Blood pressure QTL 32		0.012	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	19	20483575	57337602	Rat
61407	Scl12	Serum cholesterol level QTL 12		0.001	blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	19	13926401	30303727	Rat
61423	Cia14	Collagen induced arthritis QTL 14	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	19	10827970	43544039	Rat
9589102	Slep13	Serum leptin concentration QTL 13	4.63	0.001	blood leptin amount (VT:0005667)	plasma leptin level (CMO:0000781)	19	569374	45569374	Rat
7247442	Uae39	Urinary albumin excretion QTL 39			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	2187927	46708701	Rat
9590298	Uminl5	Urine mineral level QTL 5	3.59	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	19	1	36824771	Rat
8694186	Bw152	Body weight QTL 152	3.34	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	569374	45569374	Rat
7411590	Foco7	Food consumption QTL 7	6.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	19	1	24688055	Rat
8552935	Pigfal10	Plasma insulin-like growth factor 1 level QTL 10	5.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	19	1	36824771	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	15455860	57337602	Rat
9590250	Scort11	Serum corticosterone level QTL 11	23.45	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	19	1	36824771	Rat
9590090	Insglur8	Insulin/glucose ratio QTL 8	10.81	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	19	1	36824771	Rat
10054132	Srcrt9	Stress Responsive Cort QTL 9	2.87	0.0017	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	19	1	27355345	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	87
Count of miRNA genes:	71
Interacting mature miRNAs:	81
Transcripts:	ENSRNOT00000007726
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium					2
Low	2	31	14	6	17	6			6	22	27	11
Below cutoff	1	12	41	34		34	4	5	63	13	14		4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001105943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001395124	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255227	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255228	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097529	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000007726 ⟹ ENSRNOP00000007726

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	24,109,972 - 24,121,938 (+)	Ensembl
Rnor_6.0 Ensembl	19	25,151,995 - 25,163,957 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000085630 ⟹ ENSRNOP00000069777

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	19	25,149,897 - 25,164,086 (-)	Ensembl

RefSeq Acc Id:

NM_001105943 ⟹ NP_001099413

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	24,109,972 - 24,121,938 (+)	NCBI
Rnor_6.0	19	25,151,995 - 25,163,957 (-)	NCBI
Rnor_5.0	19	36,128,834 - 36,140,875 (-)	NCBI
RGSC_v3.4	19	25,795,355 - 25,807,317 (+)	RGD
Celera	19	23,657,895 - 23,669,746 (+)	RGD

Sequence:

show sequence

GTAAGACCCAGGCCTGGCGGTGTCACTTGTCCCTGAGAGTCATGAGCTGGCTCCGGGTTGCACG
CCTCAAGCCGTTGGAGCTTCTACTGCCGCTGCTACCACTGCTGCTCGGGACGCGGCCCCATGGC
AGTCCAGGCCCACTGCAGTGCTACAGCGTTGGCCCCTTGGGAATCCTGAACTGCTCTTGGGAAC
CTCTGGGCGACCTGGAGACTCCCCCTGTGCTGTATCACCAGAGTCAGAAATACCATCCCAATAG
AACTAAGGAGGTGAAGGTGCCTTCCAGACAGAGCTGGGTGACCATTCCCCGGAAACAGTTCACC
ACGGCTGACGAACTCCTCATCTGGGGGACACAAGAAGGACAACTTCTCTGGCCCCCTGTCTCTG
TGAACCTGGAGACCCAAATGAAGCCAGACACCCCCCAGATCTTCTCTGATGTGGACTTTTTTAA
GGAAGAAACCCTGGAGGCCATTGTGCAGTGGGAACCACCGAAGTGGCCACTGCATAAAGTCCTC
ATCTGTCAGTTCCGGTACAAAAAATGCCAGACTAAAGAGTGGACCCAGCTGGAGCCACAGCTGA
AGACAGACCTGATGACTCCTATTGAGATGCAGAACCTGGAACCTGGCACGGGCTACCAGGTATC
TGGCCGCTGCCAAGTGGAGAATGGATATCCATGGGGCGAGTGGAGCCCGGACCTGTCGTTCCCG
ACGCCATTCTTGGCTCCTGAAGATGTGTGGGTATCGGGGACCATCTGTGAAACATCTGGCAAAC
CGGCAGCCCTGCTCTTCTGGAAGGACCCAGGACCCTGTGTGCAAGTGACTTACACAGTCTGGCT
TGGGGTCGGAGATGTTACTACAACCCAAGAAGAGGTCCCGTGCTGCAAGTCCCCTATCCCTGCA
CAGATAGAGTGGGCAGTGGTCTCTACTGGCAACCAGACCAGCTGGATGCCTCTCACCAACCTGT
CTTTGGTGTGCTTGGCTCCAGAATCTGCCCCCTGTGATGTGAGAGTCAGCAGTACTGACGGGAG
CCCAGGGATAAAGGTGACCTGGAAACAAGAAACTGGGAAACCATGGGCATACGTGGTAGACTGG
GCTCAAGATGGTGACAGCCTGGACAAGCTCAACTGGACCCGTCTCCCCCCGGAAAACCTCAGCA
CTTTGTTATCAGTGAGCAGTCAAACCAAGACTGTCACTCTGCCCAACCTTTACTCGGGTCCCTT
CAAGCTGTGGGTGATGGTGTCCACCGCTGCAGGACAGGGCCCACCTGGTCCCAGCCTTTCACTT
CACATACCAGATAATAGGATCAGGTGGAAATTTCTGCCCTGGGTTCTGTCCCTGTGGGGCTTGC
TTCTGGTGGGCTGTGGCCTGAGCCTGGCCCCTCCCAGGTCCCTGCTGGCCAGGTGCTTATACCA
GAGACACAAGTTGCTTCCCCAATGGATCTGGGAGAGAGTTCCTGACCCTGCCAACAGCAATTCT
GGGCAACCTTACATAAAGGAGGTGAGCCTGCCCCAACCACCCAAAGACGGACCCATCCTGGAGG
TAGAGGAAATGGAGCTACAGCCTGTTACAGAGTCCCCTAAAGCCTCTGTCCCACTTTACTCTGG
GTATGAGAAACACTTCCTGCCCACACCAGAGGAGCTGGGCCTTCTGAGGCCTCCAGCCCCCAGA
GTTCTAGACTGTTCTGCTTCAGGCTAGGGGCTGTATCCCTATCTTGGGTTAGACATTTTTAGTT
TTAGTTTTTTGAGACTGGATCTCACTATGGCTGGCCTGAAACTCACAGAGACTCACCTGGTTCT
GCCTCCCAAGGACTGAAAAGAAAGGAGTGTGCCACCATGCCCCAACCAACTTTGTTTTTCTTGC
CTCTGTGTCTTTGACATCTGTTTGCTACTGCAGAAGAATTAATGTTCTCACAGCCACAACTCTT
TTGTTGTTCTTTGCCTCAGTTCGTCAGAGGCTTGATAGGTAGCCAAGGCTGGTCTCCAACTTGT
GATCCTCCTGTTGCAGCATCCCCAATGCTAGGATTCCAGGTGTCTTATCTCATCCAGTCATAAC
CTTTGATTATAATAAGAACAACTTCCAAGCAGGCTATGAGGAGGTGATTCGGAAGACACGTTCA
AGGGCCTGAACCGGTTAAGAGCCCTTGTTTTCTTGCAGTAGACCAAAGTTTGGTTCCCTGCCCT
TGCAGAAGACCCAGGTTCAGTTAGCACCCACAGGGCAGCTCAGAATCACCTGTGACTCCAGATC
TAGGGAATCAAATGCCCTCTTCTGGCTTCTGTGAGCCCTGAATGCACACGGTTACTTACGCGCA
GACAAAACACTCACACGC

hide sequence

RefSeq Acc Id:

XM_006255227 ⟹ XP_006255289

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	24,109,698 - 24,121,977 (+)	NCBI
Rnor_6.0	19	25,151,835 - 25,163,995 (-)	NCBI
Rnor_5.0	19	36,128,834 - 36,140,875 (-)	NCBI

Sequence:

show sequence

TTCCCACCAGGGGCGGGGTGGCTTCCTTCCCGCAGGTTGTAAGACCCAGGCCTGGCGGTGTCAC
TTGTCCCTGAGAGTCATGAGCTGGCTCCGGGTTGCACGCCTCAAGCCGTTGGAGCTTCTACTGC
CGCTGCTACCACTGCTGCTCGGGACGCGGCCCCATGGCAGTCCAGGCCCACTGCAGTGCTACAG
CGTTGGCCCCTTGGGAATCCTGAACTGCTCTTGGGAACCTCTGGGCGACCTGGAGACTCCCCCT
GTGCTGTATCACCAGAGTCAGAAATACCATCCCAATAGAACTAAGGAGGTGAAGGTGCCTTCCA
GACAGAGCTGGGTGACCATTCCCCGGAAACAGTTCACCACGGCTGACGAACTCCTCATCTGGGG
GACACAAGAAGGACAACTTCTCTGGCCCCCTGTCTCTGTGAACCTGGAGACCCAAATGAAGCCA
GACACCCCCCAGATCTTCTCTGATGTGGACTTTTTTAAGGAAGAAACCCTGGAGGCCATTGTGC
AGTGGGAACCACCGAAGTGGCCACTGCATAAAGTCCTCATCTGTCAGTTCCGGTACAAAAAATG
CCAGACTAAAGAGTGGACCCAGCTGGAGCCACAGCTGAAGACAGACCTGATGACTCCTATTGAG
ATGCAGAACCTGGAACCTGGCACGGGCTACCAGGTATCTGGCCGCTGCCAAGTGGAGAATGGAT
ATCCATGGGGCGAGTGGAGCCCGGACCTGTCGTTCCCGACGCCATTCTTGGCTCCTGAAGATGT
GTGGGTATCGGGGACCATCTGTGAAACATCTGGCAAACCGGCAGCCCTGCTCTTCTGGAAGGAC
CCAGGACCCTGTGTGCAAGTGACTTACACAGTCTGGCTTGGGGTCGGAGATGTTACTACAACCC
AAGAAGAGGTCCCGTGCTGCAAGTCCCCTATCCCTGCACAGATAGAGTGGGCAGTGGTCTCTAC
TGGCAACCAGACCAGCTGGATGCCTCTCACCAACCTGTCTTTGGTGTGCTTGGCTCCAGAATCT
GCCCCCTGTGATGTGAGAGTCAGCAGTACTGACGGGAGCCCAGGGATAAAGGTGACCTGGAAAC
AAGAAACTGGGAAACCATGGGCATACGTGGTAGACTGGGCTCAAGATGGTGACAGCCTGGACAA
GCTCAACTGGACCCGTCTCCCCCCGGAAAACCTCAGCACTTTGTTATCAGGGGATTTCCAAGCA
GGGGTCCCCTATCGAATTACAGTGACTTCAGTATACTCTGGAGGATTGGCTGCTGCACCCTCAG
TTTGGGGATTCATAAAGGAATTAGCACCGCTTGCTGGACCAGCAGTTTGGCGACTCCCAGATGA
CCCCACAGGGACACCTGTTGTAGCATGGGGAGAGGTACCAAGGCACCAGCTCCGAGGCCAGGCT
ACTCACTACACCTTCTGCAGGCAGAGCCGAGGCATCCCCACTATCTGCATGAATGTGAGCAGTC
AAACCAAGACTGTCACTCTGCCCAACCTTTACTCGGGTCCCTTCAAGCTGTGGGTGATGGTGTC
CACCGCTGCAGGACAGGGCCCACCTGGTCCCAGCCTTTCACTTCACATACCAGATAATAGGATC
AGGTGGAAATTTCTGCCCTGGGTTCTGTCCCTGTGGGGCTTGCTTCTGGTGGGCTGTGGCCTGA
GCCTGGCCCCTCCCAGGTGCTTATACCAGAGACACAAGTTGCTTCCCCAATGGATCTGGGAGAG
AGTTCCTGACCCTGCCAACAGCAATTCTGGGCAACCTTACATAAAGGAGGTGAGCCTGCCCCAA
CCACCCAAAGACGGACCCATCCTGGAGGTAGAGGAAATGGAGCTACAGCCTGTTACAGAGTCCC
CTAAAGCCTCTGTCCCACTTTACTCTGGGTATGAGAAACACTTCCTGCCCACACCAGAGGAGCT
GGGCCTTCTGAGGCCTCCAGCCCCCAGAGTTCTAGACTGTTCTGCTTCAGGCTAGGGGCTGTAT
CCCTATCTTGGGTTAGACATTTTTAGTTTTAGTTTTTTGAGACTGGATCTCACTATGGCTGGCC
TGAAACTCACAGAGACTCACCTGGTTCTGCCTCCCAAGGACTGAAAAGAAAGGAGTGTGCCACC
ATGCCCCAACCAACTTTGTTTTTCTTGCCTCTGTGTCTTTGACATCTGTTTGCTACTGCAGAAG
AATTAATGTTCTCACAGCCACAACTCTTTTGTTGTTCTTTGCCTCAGTTCGTCAGAGGCTTGAT
AGGTAGCCAAGGCTGGTCTCCAACTTGTGATCCTCCTGTTGCAGCATCCCCAATGCTAGGATTC
CAGGTGTCTTATCTCATCCAGTCATAACCTTTGATTATAATAAGAACAACTTCCAAGCAGGCTA
TGAGGAGGTGATTCGGAAGACACGTTCAAGGGCCTGAACCGGTTAAGAGCCCTTGTTTTCTTGC
AGTAGACCAAAGTTTGGTTCCCTGCCCTTGCAGAAGACCCAGGTTCAGTTAGCACCCACAGGGC
AGCTCAGAATCACCTGTGACTCCAGATCTAGGGAATCAAATGCCCTCTTCTGGCTTCTGTGAGC
CCTGAATGCACACGGTTACTTACGCGCAGACAAAACACTCACACGCATAAAATAAAAATAAATA
AAAGATAAATAATAAAATAAATAAACGTTTTTTTCTTAAAGCCAGAGTGCCTTAACATTTAATT
TTCAAGTATAAAGGCTTCATTGCAGAAGGAAGTCAGGGCCACAGGCAGTGGGCAGGGAATCTAA
AAGCCCAGGTGTAA

hide sequence

RefSeq Acc Id:

XM_039097529 ⟹ XP_038953457

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	24,109,963 - 24,121,977 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099413	(Get FASTA)	NCBI Sequence Viewer
	NP_001382053	(Get FASTA)	NCBI Sequence Viewer
	XP_006255289	(Get FASTA)	NCBI Sequence Viewer
	XP_038953457	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL92242	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001099413 ⟸ NM_001105943

- Peptide Label:

precursor

- Sequence:

show sequence

MSWLRVARLKPLELLLPLLPLLLGTRPHGSPGPLQCYSVGPLGILNCSWEPLGDLETPPVLYHQ
SQKYHPNRTKEVKVPSRQSWVTIPRKQFTTADELLIWGTQEGQLLWPPVSVNLETQMKPDTPQI
FSDVDFFKEETLEAIVQWEPPKWPLHKVLICQFRYKKCQTKEWTQLEPQLKTDLMTPIEMQNLE
PGTGYQVSGRCQVENGYPWGEWSPDLSFPTPFLAPEDVWVSGTICETSGKPAALLFWKDPGPCV
QVTYTVWLGVGDVTTTQEEVPCCKSPIPAQIEWAVVSTGNQTSWMPLTNLSLVCLAPESAPCDV
RVSSTDGSPGIKVTWKQETGKPWAYVVDWAQDGDSLDKLNWTRLPPENLSTLLSVSSQTKTVTL
PNLYSGPFKLWVMVSTAAGQGPPGPSLSLHIPDNRIRWKFLPWVLSLWGLLLVGCGLSLAPPRS
LLARCLYQRHKLLPQWIWERVPDPANSNSGQPYIKEVSLPQPPKDGPILEVEEMELQPVTESPK
ASVPLYSGYEKHFLPTPEELGLLRPPAPRVLDCSASG

hide sequence

RefSeq Acc Id:	XP_006255289 ⟸ XM_006255227
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JW79 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSWLRVARLKPLELLLPLLPLLLGTRPHGSPGPLQCYSVGPLGILNCSWEPLGDLETPPVLYHQ SQKYHPNRTKEVKVPSRQSWVTIPRKQFTTADELLIWGTQEGQLLWPPVSVNLETQMKPDTPQI FSDVDFFKEETLEAIVQWEPPKWPLHKVLICQFRYKKCQTKEWTQLEPQLKTDLMTPIEMQNLE PGTGYQVSGRCQVENGYPWGEWSPDLSFPTPFLAPEDVWVSGTICETSGKPAALLFWKDPGPCV QVTYTVWLGVGDVTTTQEEVPCCKSPIPAQIEWAVVSTGNQTSWMPLTNLSLVCLAPESAPCDV RVSSTDGSPGIKVTWKQETGKPWAYVVDWAQDGDSLDKLNWTRLPPENLSTLLSGDFQAGVPYR ITVTSVYSGGLAAAPSVWGFIKELAPLAGPAVWRLPDDPTGTPVVAWGEVPRHQLRGQATHYTF CRQSRGIPTICMNVSSQTKTVTLPNLYSGPFKLWVMVSTAAGQGPPGPSLSLHIPDNRIRWKFL PWVLSLWGLLLVGCGLSLAPPRCLYQRHKLLPQWIWERVPDPANSNSGQPYIKEVSLPQPPKDG PILEVEEMELQPVTESPKASVPLYSGYEKHFLPTPEELGLLRPPAPRVLDCSASG hide sequence

RefSeq Acc Id:

ENSRNOP00000069777 ⟸ ENSRNOT00000085630

RefSeq Acc Id:

ENSRNOP00000007726 ⟸ ENSRNOT00000007726

RefSeq Acc Id:	XP_038953457 ⟸ XM_039097529
- Peptide Label:	isoform X2

Protein Domains

Fibronectin type-III

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2JW79-F1-model_v2	AlphaFold	A0A0G2JW79	1-631	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701011

Promoter ID:

EPDNEW_R11534

Type:

initiation region

Name:

Il27ra_1

Description:

interleukin 27 receptor subunit alpha

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	19	25,163,929 - 25,163,989	EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)

ACI/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN-Lx/CubMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BUF/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH2/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH3/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

DA/OlaHsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/DuCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE16/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE18/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GK/FarMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB10/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB2/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB20/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB31/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB4/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEW/Crl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF10A/StmMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF11/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1A/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1C/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF2B/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF3/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF4/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LH/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LL/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LN/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/NRrrcMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MR/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MWF/Hsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

PVG/Seac (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHR/OlalpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/A3NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SR/JrHsd (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SS/JrHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WAG/RijCrl (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WN/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305029	AgrOrtholog
BioCyc Gene	G2FUF-6050	BioCyc
Ensembl Genes	ENSRNOG00000005747	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000007726	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000069777	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000007726	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOT00000085630	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	FN3_sf	UniProtKB/TrEMBL
	FN_III	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
KEGG Report	rno:288905	UniProtKB/TrEMBL
NCBI Gene	288905	ENTREZGENE
Pfam	fn3	UniProtKB/TrEMBL
PhenoGen	Il27ra	PhenoGen
PROSITE	FN3	UniProtKB/TrEMBL
SMART	FN3	UniProtKB/TrEMBL
Superfamily-SCOP	FN_III-like	UniProtKB/TrEMBL
UniProt	A0A0G2JW79	ENTREZGENE, UniProtKB/TrEMBL
	D4A6K5_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-16	Il27ra	interleukin 27 receptor subunit alpha	Il27ra	interleukin 27 receptor, alpha	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Il27ra	interleukin 27 receptor, alpha	Il27ra_predicted	interleukin 27 receptor, alpha (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Il27ra_predicted	interleukin 27 receptor, alpha (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

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Imported Disease Annotations - CTD

Imported Annotations - PID (archival)