Gene: Nr3c2 (nuclear receptor subfamily 3, group C, member 2) Rattus norvegicus
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Symbol: Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity; double-stranded DNA binding; protein heterodimerization activity; INVOLVED IN regulation of cell population proliferation; cellular sodium ion homeostasis (ortholog); excretion (ortholog); PARTICIPATES IN aldosterone signaling pathway; amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); autosomal dominant pseudohypoaldosteronism type 1 (ortholog); FOUND IN cytoplasm; glutamatergic synapse; nucleus; INTERACTS WITH (S)-nicotine; 11-deoxycorticosterone; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MCR; mineralocorticoid receptor; Mineralocorticoid receptor (aldosterone receptor); Mlr; MR; nuclear receptor subfamily 3 group C member 2
Orthologs:
Is Marker For: QTLs:   Salc2   Gmadr1   Bw28  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01934,408,275 - 34,761,003 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01945,287,442 - 45,639,834 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41932,527,752 - 32,875,369 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11932,532,632 - 32,880,250 (-)NCBI
Celera1930,192,512 - 30,534,995 (-)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nr3c2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3094
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-02-05
Status: ACTIVE