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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3094
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Acc ID: CHEBI:50885
Term: fludrocortisone
Definition: A mineralocorticoid that has formula C21H29FO5.
Chemical ID: MESH:D005438
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr3c2multiple interactionsISONR3C2 (Homo sapiens)6480464CTD[Fludrocortisone binds to and results in increased activity of NR3C2 protein] which results in decreased abundance of Hydrocortisone; [Fludrocortisone binds to and results in increased activity of NR3C2 protein] which results in decreased expression of POMC proteinPMID:16566900
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