Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3094
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Acc ID: CHEBI:9637
Term: torasemide
Definition: An N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea. It is a potent loop diuretic used for the treatment of hypertension and edema in patients with congestive heart failure.
Chemical ID: MESH:C026116
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr3c2multiple interactionsEXP 6480464CTDTorsemide inhibits the reaction [Aldosterone binds to NR3C2 protein]

PMID:7954537
Go Back to source page   Continue to Ontology report