GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nr3c2 | affects expression | EXP | | 6480464 | CTD | bisphenol A affects the expression of NR3C2 mRNA | PMID:24857958 PMID:25181051 | Nr3c2 | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of NR3C2 mRNA | PMID:30816183 | Nr3c2 | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of NR3C2 mRNA | PMID:26060449 PMID:36136478 | Nr3c2 | increases methylation | EXP | | 6480464 | CTD | bisphenol A results in increased methylation of NR3C2 gene | PMID:28505145 | Nr3c2 | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NR3C2 mRNA | PMID:25607892 | Nr3c2 | multiple interactions | ISO | Nr3c2 (Mus musculus) | 6480464 | CTD | [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NR3C2 mRNA | PMID:32518293 | Nr3c2 | multiple interactions | ISO | NR3C2 (Homo sapiens) | 6480464 | CTD | [bisphenol A co-treated with Fulvestrant] results in increased methylation of NR3C2 gene; bisphenol A inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] | PMID:30951782 PMID:31601247 | |
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