Dync1li2 (dynein, cytoplasmic 1 light intermediate chain 2) - Rat Genome Database

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Gene: Dync1li2 (dynein, cytoplasmic 1 light intermediate chain 2) Rattus norvegicus
Analyze
Symbol: Dync1li2
Name: dynein, cytoplasmic 1 light intermediate chain 2
RGD ID: 621130
Description: Exhibits identical protein binding activity. Involved in cellular response to nerve growth factor stimulus. Localizes to centrosome and kinetochore. Colocalizes with late endosome and lysosome. Orthologous to human DYNC1LI2 (dynein cytoplasmic 1 light intermediate chain 2); PARTICIPATES IN mitochondria transport pathway; phagocytosis pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cytoplasmic dynein 1 light intermediate chain 2; Dncli2; dynein light intermediate chain 2, cytosolic; dynein, cytoplasmic, light intermediate polypeptide 2; LIC-2 dynein light intermediate chain 53/55; Lic2; LIC53/55; MGC108664
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.219531,783 - 554,670 (+)NCBI
Rnor_6.0 Ensembl19740,028 - 762,897 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.019740,007 - 762,897 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.019738,990 - 762,115 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.419469,163 - 510,647 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.119469,162 - 510,647 (+)NCBI
Celera19527,460 - 550,605 (+)NCBICelera
Cytogenetic Map19p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Weight Gain  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:12477932   PMID:19540120   PMID:19946888   PMID:21399614   PMID:21700703   PMID:26227614   PMID:30674581   PMID:31505169  


Genomics

Comparative Map Data
Dync1li2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.219531,783 - 554,670 (+)NCBI
Rnor_6.0 Ensembl19740,028 - 762,897 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.019740,007 - 762,897 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.019738,990 - 762,115 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.419469,163 - 510,647 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.119469,162 - 510,647 (+)NCBI
Celera19527,460 - 550,605 (+)NCBICelera
Cytogenetic Map19p14NCBI
DYNC1LI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1666,720,893 - 66,751,609 (-)EnsemblGRCh38hg38GRCh38
GRCh381666,720,893 - 66,751,609 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371666,754,796 - 66,785,512 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361665,312,300 - 65,343,026 (-)NCBINCBI36hg18NCBI36
Build 341665,312,299 - 65,343,026NCBI
Celera1651,262,971 - 51,293,905 (-)NCBI
Cytogenetic Map16q22.1NCBI
HuRef1652,629,870 - 52,660,679 (-)NCBIHuRef
CHM1_11668,161,880 - 68,192,810 (-)NCBICHM1_1
Dync1li2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398105,144,306 - 105,170,415 (-)NCBIGRCm39mm39
GRCm39 Ensembl8105,144,312 - 105,169,679 (-)Ensembl
GRCm388104,417,674 - 104,443,050 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8104,417,680 - 104,443,047 (-)EnsemblGRCm38mm10GRCm38
MGSCv378106,941,574 - 106,966,947 (-)NCBIGRCm37mm9NCBIm37
MGSCv368107,308,253 - 107,332,134 (-)NCBImm8
Celera8108,648,540 - 108,674,331 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
Dync1li2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543323,262,981 - 23,287,067 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543323,262,981 - 23,286,506 (-)NCBIChiLan1.0ChiLan1.0
DYNC1LI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11666,141,323 - 66,170,693 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1666,141,323 - 66,170,693 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01647,038,975 - 47,069,849 (-)NCBIMhudiblu_PPA_v0panPan3
DYNC1LI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1582,539,880 - 82,566,689 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl582,539,876 - 82,563,905 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha582,528,033 - 82,555,123 (+)NCBI
ROS_Cfam_1.0582,976,226 - 83,003,337 (+)NCBI
UMICH_Zoey_3.1582,799,354 - 82,826,459 (+)NCBI
UNSW_CanFamBas_1.0582,486,217 - 82,513,307 (+)NCBI
UU_Cfam_GSD_1.0583,124,764 - 83,151,903 (+)NCBI
Dync1li2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934942,552,874 - 42,576,200 (+)NCBI
SpeTri2.0NW_00493647517,012,911 - 17,036,290 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNC1LI2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl627,416,477 - 27,446,360 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1627,416,475 - 27,446,172 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DYNC1LI2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1552,416,645 - 52,448,754 (-)NCBI
ChlSab1.1 Ensembl552,419,479 - 52,448,901 (-)Ensembl
Dync1li2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474619,727,861 - 19,752,220 (+)NCBI


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124933090Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127635288Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19129558305Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19129558305Rat
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19132379055Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19138221845Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19138221845Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19138221845Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19138221845Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:448
Count of miRNA genes:233
Interacting mature miRNAs:310
Transcripts:ENSRNOT00000034472
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000034472   ⟹   ENSRNOP00000029646
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl19740,227 - 762,897 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000075978   ⟹   ENSRNOP00000068436
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl19752,151 - 760,090 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076337
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl19753,492 - 756,193 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076353
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl19758,190 - 760,588 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076560   ⟹   ENSRNOP00000067912
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl19755,460 - 760,243 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076604   ⟹   ENSRNOP00000068268
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl19740,028 - 761,527 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076742   ⟹   ENSRNOP00000067920
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl19740,125 - 760,168 (+)Ensembl
RefSeq Acc Id: NM_031026   ⟹   NP_112288
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.219531,999 - 554,669 (+)NCBI
Rnor_6.019740,227 - 762,896 (+)NCBI
Rnor_5.019738,990 - 762,115 (+)NCBI
RGSC_v3.419469,163 - 510,647 (+)RGD
Celera19527,460 - 550,605 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255053   ⟹   XP_006255115
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.219531,784 - 554,670 (+)NCBI
Rnor_6.019740,008 - 762,897 (+)NCBI
Rnor_5.019738,990 - 762,115 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006255054   ⟹   XP_006255116
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.219531,783 - 554,670 (+)NCBI
Rnor_6.019740,007 - 762,897 (+)NCBI
Rnor_5.019738,990 - 762,115 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039098021   ⟹   XP_038953949
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.219531,783 - 548,171 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_112288   ⟸   NM_031026
- UniProtKB: Q62698 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006255116   ⟸   XM_006255054
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006255115   ⟸   XM_006255053
- Peptide Label: isoform X1
- UniProtKB: Q5D023 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000068436   ⟸   ENSRNOT00000075978
RefSeq Acc Id: ENSRNOP00000029646   ⟸   ENSRNOT00000034472
RefSeq Acc Id: ENSRNOP00000068268   ⟸   ENSRNOT00000076604
RefSeq Acc Id: ENSRNOP00000067920   ⟸   ENSRNOT00000076742
RefSeq Acc Id: ENSRNOP00000067912   ⟸   ENSRNOT00000076560
RefSeq Acc Id: XP_038953949   ⟸   XM_039098021
- Peptide Label: isoform X3

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700919
Promoter ID:EPDNEW_R11434
Type:multiple initiation site
Name:Dync1li2_1
Description:dynein, cytoplasmic 1 light intermediate chain 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.019740,222 - 740,282EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621130 AgrOrtholog
Ensembl Genes ENSRNOG00000025791 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000029646 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000067912 UniProtKB/TrEMBL
  ENSRNOP00000067920 UniProtKB/TrEMBL
  ENSRNOP00000068268 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000068436 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000034472 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000075978 UniProtKB/TrEMBL
  ENSRNOT00000076560 UniProtKB/TrEMBL
  ENSRNOT00000076604 UniProtKB/TrEMBL
  ENSRNOT00000076742 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7115029 IMAGE-MGC_LOAD
InterPro Dynein1_light_intermed_chain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_light_int_chain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81655 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108664 IMAGE-MGC_LOAD
NCBI Gene 81655 ENTREZGENE
PANTHER PTHR12688 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DLIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dync1li2 PhenoGen
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A096MIX4_RAT UniProtKB/TrEMBL
  A0A096MIY2_RAT UniProtKB/TrEMBL
  A0A096MKA1_RAT UniProtKB/TrEMBL
  DC1L2_RAT UniProtKB/Swiss-Prot
  Q5D023 ENTREZGENE, UniProtKB/TrEMBL
  Q62698 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-19 Dync1li2  dynein, cytoplasmic 1 light intermediate chain 2  Dncli2  dynein, cytoplasmic, light intermediate polypeptide 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Dncli2  dynein, cytoplasmic, light intermediate polypeptide 2    LIC-2 dynein light intermediate chain 53/55  Name updated 1299863 APPROVED
2002-08-07 Dncli2  LIC-2 dynein light intermediate chain 53/55      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_product region of cDNA shares homology with ABC transporter family of ATPases 728207
gene_protein cDNA sequence contains 497 codon open reading frame, encodes a 55 kDa polypeptide 728207