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Gene: Cdh1 (cadherin 1) Rattus norvegicus
Symbol: Cdh1
Name: cadherin 1
Description: Predicted to have several functions, including GTPase activating protein binding activity; alpha-catenin binding activity; and ankyrin binding activity. Involved in several processes, including nervous system development; regulation of protein catabolic process at postsynapse, modulating synaptic transmission; and response to toxic substance. Localizes to several cellular components, including glutamatergic synapse; plasma membrane; and postsynapse. Predicted to colocalize with cortical actin cytoskeleton. Used to study hepatocellular carcinoma and lung adenocarcinoma. Biomarker of pulmonary fibrosis and urinary bladder cancer. Human ortholog(s) of this gene implicated in several diseases, including blepharocheilodontic syndrome 1; breast cancer (multiple); carcinoma (multiple); cervix uteri carcinoma in situ; and reproductive organ cancer (multiple). Orthologous to human CDH1 (cadherin 1); PARTICIPATES IN E-cadherin signaling pathway; fibroblast growth factor signaling pathway; endometrial cancer pathway; INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; (R)-carnitine.
Type: protein-coding
Also known as: cadherin-1; E-cadherin; epithelial cadherin; uvomorulin
Homo sapiens (human) : CDH1 (cadherin 1)  HGNC  Alliance
Mus musculus (house mouse) : Cdh1 (cadherin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdh1 (cadherin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CDH1 (cadherin 1)
Canis lupus familiaris (dog) : CDH1 (cadherin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdh1 (cadherin 1)
Sus scrofa (pig) : CDH1 (cadherin 1)
Chlorocebus sabaeus (African green monkey) : CDH1 (cadherin 1)
Heterocephalus glaber (naked mole-rat) : Cdh1 (cadherin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01938,768,467 - 38,838,395 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1938,768,467 - 38,838,395 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01949,635,965 - 49,705,893 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41936,442,693 - 36,512,091 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11936,447,573 - 36,516,972 (+)NCBI
Celera1933,919,043 - 33,988,306 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)