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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDmethylmercuric chloride results in increased expression of CDH1 mRNA, methylmercuric chloride results in increased expression of CDH1 protein

PMID:20864626, PMID:28526320
affects expressionISORGD:7374146480464CTDmethylmercuric chloride affects the expression of CDH1 mRNA

PMID:21613230
decreases expressionISORGD:7374136480464CTDmethylmercuric chloride results in decreased expression of CDH1 mRNA

PMID:23179753, PMID:27188386
increases expressionISORGD:7374136480464CTDmethylmercuric chloride results in increased expression of CDH1 mRNA

PMID:23179753, PMID:26272509
multiple interactionsISORGD:7374136480464CTD[NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CDH1 mRNA

PMID:27188386
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.