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Gene: Cdh1 (cadherin 1) Mus musculus
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Symbol: Cdh1
Name: cadherin 1
RGD ID: 737414
Description: Exhibits several functions, including alpha-catenin binding activity; beta-catenin binding activity; and identical protein binding activity. Involved in several processes, including animal organ development; epithelial cell development; and regulation of proteolysis. Localizes to several cellular components, including Schmidt-Lanterman incisure; axon; and catenin complex. Predicted to colocalize with cortical actin cytoskeleton. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including blepharocheilodontic syndrome 1; breast cancer (multiple); cervix uteri carcinoma in situ; gastrointestinal system cancer (multiple); and reproductive organ cancer (multiple). Orthologous to human CDH1 (cadherin 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA960649; ARC-1; cadherin-1; E-ca; E-cad; E-cadh; E-cadherin; Eca; Ecad; epithelial cadherin; L-C; L-CAM; MGC107495; Um; UVO; uvomorulin
Orthologs:
Homo sapiens (human) : CDH1 (cadherin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdh1 (cadherin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdh1 (cadherin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CDH1 (cadherin 1)
Canis lupus familiaris (dog) : CDH1 (cadherin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdh1 (cadherin 1)
Sus scrofa (pig) : CDH1 (cadherin 1)
Chlorocebus sabaeus (African green monkey) : CDH1 (cadherin 1)
Heterocephalus glaber (naked mole-rat) : Cdh1 (cadherin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Note: CDH1 (GeneID 12550) and FZR1 (GeneID 56371) share the CDH1 symbol. CDH1 is sometimes used as an abbreviation for 'CDC20 homolog 1' which is an alternate name for the FZR1 gene and thus can be confused with the official symbol for cadherin 1 (CDH1). [16 Jul 2018]
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398107,329,982 - 107,396,879 (+)NCBI
GRCm388106,603,350 - 106,670,247 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8106,603,351 - 106,670,246 (+)EnsemblGRCm38mm10GRCm38
MGSCv378109,127,268 - 109,194,146 (+)NCBIGRCm37mm9NCBIm37
MGSCv368109,492,497 - 109,559,375 (+)NCBImm8
Celera8110,827,793 - 110,895,640 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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