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Gene: Cdh1 (cadherin 1) Mus musculus
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Symbol: Cdh1
Name: cadherin 1
Description: This gene encodes E-cadherin, a calcium-dependent cell adhesion molecule that functions in the establishment and maintenance of epithelial cell morphology during embryongenesis and adulthood. The encoded preproprotein undergoes proteolytic processing to generate a mature protein. Targeted mutations disrupting binding of calcium to the encoded protein in mice cause death in utero due to failed blastocyst and trophectoderm formation. This gene is located adjacent to a related cadherin gene on chromosome 8. [provided by RefSeq, Oct 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA960649; ARC-1; cadherin-1; E-cad; E-cadherin; Ecad; epithelial cadherin; L-CAM; MGC107495; Um; UVO; uvomorulin
Orthologs:
Homo sapiens (human) : CDH1 (cadherin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdh1 (cadherin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdh1 (cadherin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CDH1 (cadherin 1)
Canis lupus familiaris (dog) : CDH1 (cadherin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdh1 (cadherin 1)
Sus scrofa (pig) : CDH1 (cadherin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Note: CDH1 (GeneID 12550) and FZR1 (GeneID 56371) share the CDH1 symbol. CDH1 is sometimes used as an abbreviation for 'CDC20 homolog 1' which is an alternate name for the FZR1 gene and thus can be confused with the official symbol for cadherin 1 (CDH1). [16 Jul 2018]
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm388106,603,350 - 106,670,247 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv378109,127,268 - 109,194,146 (+)NCBIGRCm37mm9NCBIm37
MGSCv368109,492,497 - 109,559,375 (+)NCBImm8
Celera8110,827,793 - 110,895,640 (+)NCBICelera
Cytogenetic Map8 D3NCBI
cM Map853.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated