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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:50182
Term: 3,3'-diindolylmethane
Definition: An indole that has formula C17H14N2.
Chemical ID: MESH:C016392
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7374136480464CTD3, 3'-diindolylmethane inhibits the reaction [bisphenol A results in decreased expression of CDH1 protein], 3, 3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of CDH1 protein], 3, 3'-diindolylmethane inhibits the reaction [Triclosan results in decreased expression of CDH1 protein]

PMID:28844962
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.