Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ctnnb1 (catenin beta 1) Rattus norvegicus
Symbol: Ctnnb1
Name: catenin beta 1
Description: Exhibits cadherin binding activity; ionotropic glutamate receptor binding activity; and nitric-oxide synthase binding activity. Involved in several processes, including cellular response to insulin-like growth factor stimulus; cellular response to lithium ion; and cellular response to mechanical stimulus. Localizes to several cellular components, including dendritic shaft; intercalated disc; and nuclear membrane. Colocalizes with neuron projection. Used to study colon adenocarcinoma and lung carcinoma. Biomarker of Alzheimer's disease and colorectal cancer. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant non-syndromic intellectual disability 19; exudative vitreoretinopathy 7; hepatocellular carcinoma (multiple); reproductive organ cancer (multiple); and urinary system cancer (multiple). Orthologous to human CTNNB1 (catenin beta 1); PARTICIPATES IN Wnt signaling, canonical pathway; altered Wnt signaling, canonical pathway; colorectal cancer pathway; INTERACTS WITH (+)-pilocarpine; (-)-epigallocatechin 3-gallate; (R)-adrenaline.
Type: protein-coding
Also known as: beta-catenin; catenin (cadherin associated protein), beta 1; catenin (cadherin associated protein), beta 1, 88kDa; catenin beta; catenin beta-1; Catnb
Homo sapiens (human) : CTNNB1 (catenin beta 1)  HGNC  Alliance
Mus musculus (house mouse) : Ctnnb1 (catenin (cadherin associated protein), beta 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ctnnb1 (catenin beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CTNNB1 (catenin beta 1)
Canis lupus familiaris (dog) : CTNNB1 (catenin beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctnnb1 (catenin beta 1)
Sus scrofa (pig) : CTNNB1 (catenin beta 1)
Chlorocebus sabaeus (African green monkey) : CTNNB1 (catenin beta 1)
Heterocephalus glaber (naked mole-rat) : Ctnnb1 (catenin beta 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.08129,601,511 - 129,628,378 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8129,617,812 - 129,627,372 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08128,798,888 - 128,825,828 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48125,978,161 - 125,987,670 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18125,997,897 - 126,007,407 (+)NCBI
Celera8119,795,816 - 119,805,325 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)