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Gene: Ctnnb1 (catenin beta 1) Rattus norvegicus
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Symbol: Ctnnb1
Name: catenin beta 1
Description: Exhibits cadherin binding activity; ionotropic glutamate receptor binding activity; and nitric-oxide synthase binding activity. Involved in several processes, including cellular response to insulin-like growth factor stimulus; cellular response to lithium ion; and cellular response to mechanical stimulus. Localizes to several cellular components, including the cytoplasm; dendritic shaft; and intercalated disc. Colocalizes with the neuron projection. Used to study colon adenocarcinoma and lung carcinoma. Biomarker of Alzheimer's disease and colorectal cancer. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant non-syndromic intellectual disability 19; endocrine gland cancer (multiple); exudative vitreoretinopathy 7; pilomatrixoma; and urinary system cancer (multiple). Orthologous to human CTNNB1 (catenin beta 1); PARTICIPATES IN Wnt signaling, canonical pathway; altered Wnt signaling, canonical pathway; colorectal cancer pathway; INTERACTS WITH (+)-pilocarpine; (-)-epigallocatechin 3-gallate; (R)-adrenaline.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: beta-catenin; catenin (cadherin associated protein), beta 1; catenin (cadherin associated protein), beta 1, 88kDa; catenin beta; catenin beta-1; Catnb
Orthologs:
Homo sapiens (human) : CTNNB1 (catenin beta 1)  HGNC  Alliance
Mus musculus (house mouse) : Ctnnb1 (catenin (cadherin associated protein), beta 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ctnnb1 (catenin beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CTNNB1 (catenin beta 1)
Canis lupus familiaris (dog) : CTNNB1 (catenin beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctnnb1 (catenin beta 1)
Sus scrofa (pig) : CTNNB1 (catenin beta 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08129,601,511 - 129,628,378 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08128,798,888 - 128,825,828 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48125,978,161 - 125,987,670 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18125,997,897 - 126,007,407 (+)NCBI
Celera8119,795,816 - 119,805,325 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations