Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7374136480464CTDresveratrol results in decreased expression of CDH1 protein

PMID:18089832
increases expressionISORGD:7374136480464CTDresveratrol results in increased expression of CDH1 mRNA, resveratrol results in increased expression of CDH1 protein

PMID:20637737, PMID:20706672, PMID:22692956, PMID:23921149, PMID:23992306, PMID:25896424, PMID:26310874
multiple interactionsISORGD:7374136480464CTDresveratrol inhibits the reaction [Fluorouracil results in decreased expression of CDH1 protein], resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of CDH1 mRNA], resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of CDH1 protein], resveratrol inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 mRNA], resveratrol inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]

PMID:23146760, PMID:23992306, PMID:25069516, PMID:25884904, PMID:26310874
multiple interactionsISORGD:7374146480464CTDresveratrol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of CDH1 protein]

PMID:25234611
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.