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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:50102
Term: N-methyl-N-nitrosourea
Definition: A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups.
Chemical ID: MESH:D008770
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Methylnitrosourea co-treated with Testosterone] results in decreased expression of CDH1 mRNA, [Methylnitrosourea co-treated with Testosterone] results in decreased expression of CDH1 protein, Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in decreased expression of CDH1 mRNA], Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in decreased expression of CDH1 protein]

PMID:25164625
decreases expressionISORGD:7374136480464CTDMethylnitrosourea results in decreased expression of CDH1 mRNA

PMID:27221058
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.