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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdh1decreases expressionISOCDH1 (Homo sapiens)6480464CTDGlucose results in decreased expression of CDH1 mRNA; Glucose results in decreased expression of CDH1 proteinPMID:21829520 PMID:26045780 PMID:29163160 PMID:33992720 PMID:35445903
Cdh1multiple interactionsISOCDH1 (Homo sapiens)6480464CTD4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Glucose results in decreased expression of CDH1 protein]; [Glucose co-treated with TGFB1 protein] results in decreased expression of CDH1 protein; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of CDH1 protein]; DKK1 protein inhibits the reaction [Glucose results in decreased expression of CDH1 mRNA]; DKK1 protein inhibits the reaction [Glucose results in decreased expression of CDH1 protein]; MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of CDH1 protein]; MAPK14 protein promotes the reaction [Glucose results in decreased expression of CDH1 protein]PMID:21829520 PMID:26045780 PMID:29163160 PMID:35961541
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