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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:53556
Term: toluene 2,4-diisocyanate
Definition: A toluene meta-diisocyanate in which the isocyanato groups are at positions 2 and 4 relative to the methyl group on the benzene ring.
Chemical ID: MESH:D014051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdh1affects localizationISOCdh1 (Mus musculus)6480464CTDToluene 2,4-Diisocyanate affects the localization of CDH1 proteinPMID:30517707
Cdh1multiple interactionsISOCdh1 (Mus musculus)6480464CTD2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [Toluene 2,4-Diisocyanate affects the localization of CDH1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Toluene 2,4-Diisocyanate affects the localization of CDH1 protein]; GSK2193874 inhibits the reaction [Toluene 2,4-Diisocyanate affects the localization of CDH1 protein]; Toluene 2,4-Diisocyanate results in decreased expression of and affects the localization of CDH1 proteinPMID:26089345 PMID:30517707
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