Il15 (interleukin 15) - Rat Genome Database

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Gene: Il15 (interleukin 15) Rattus norvegicus
Analyze
Symbol: Il15
Name: interleukin 15
RGD ID: 2887
Description: Predicted to have cytokine activity. Involved in several processes, including cellular response to vitamin D; positive regulation of tyrosine phosphorylation of STAT protein; and skeletal muscle atrophy. Localizes to cell surface and extracellular space. Used to study pancreatitis. Biomarker of listeriosis and periodontal disease. Human ortholog(s) of this gene implicated in aspergillosis; asthma; pleurisy; and type 1 diabetes mellitus. Orthologous to human IL15 (interleukin 15); PARTICIPATES IN Jak-Stat signaling pathway; cytokine mediated signaling pathway; rheumatoid arthritis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-di-tert-butyl-4-methylphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: IL-15; interleukin-15
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Il15em1Soar  
Genetic Models: SD-Il15em1Soar
Is Marker For: Strains:   SD-Il15em1Soar  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21925,640,013 - 25,706,818 (+)NCBI
Rnor_6.0 Ensembl1923,542,889 - 23,554,594 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01923,542,606 - 23,624,366 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01934,532,033 - 34,598,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41927,487,268 - 27,498,973 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11927,437,760 - 27,504,081 (+)NCBI
Celera1925,174,648 - 25,228,568 (+)NCBICelera
Celera1925,228,574 - 25,240,279 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsenous acid  (ISO)
asperentin  (ISO)
atrazine  (EXP)
belinostat  (ISO)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
chrysin  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
D-penicillamine  (EXP)
deoxynivalenol  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP,ISO)
diarsenic trioxide  (ISO)
diethyl malate  (ISO)
dioxygen  (ISO)
divanadium pentaoxide  (ISO)
emodin  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
glyphosate  (ISO)
hexachlorobenzene  (EXP)
irinotecan  (EXP)
levamisole  (ISO)
lipid As  (ISO)
lipopolysaccharide  (ISO)
m-xylene  (EXP)
methyl methanesulfonate  (ISO)
muramyl dipeptide  (ISO)
mycophenolic acid  (ISO)
mycotoxin  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-acetyl-L-cysteine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nonanoic acid  (ISO)
notoginsenoside R1  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
PD 0325901  (ISO)
permethrin  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
Pyridostigmine bromide  (EXP)
quercitrin  (ISO)
quinolin-8-ol  (ISO)
riddelliine  (EXP)
rotenone  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sterigmatocystin  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
tofacitinib  (ISO)
toluene 2,4-diisocyanate  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell surface  (IDA)
cytoplasm  (ISO)
cytosol  (IEA,ISO)
extracellular space  (IBA,IDA)
nuclear speck  (IEA,ISO)
nucleoplasm  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
1. Abebe F, etal., Clin Exp Immunol. 2006 Jan;143(1):180-92.
2. Almansa R, etal., J Interferon Cytokine Res. 2011 Jan 15.
3. Aoi N, etal., J Allergy Clin Immunol. 2006 Jun;117(6):1359-66. Epub 2006 Apr 3.
4. Bermejo-Martin JF, etal., Crit Care. 2009;13(6):R201. Epub 2009 Dec 11.
5. Bierbaum S, etal., Allergy. 2006 May;61(5):576-80.
6. Cercek M, etal., Biochem Biophys Res Commun. 2006 Jan 13;339(2):618-23. Epub 2005 Nov 18.
7. Chomej P, etal., Respir Med. 2004 Apr;98(4):308-17.
8. Desai B, etal., Exp Lung Res. 2011 May;37(4):227-38. Epub 2011 Feb 11.
9. Galkowska H, etal., Wound Repair Regen. 2006 Sep-Oct;14(5):558-65.
10. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
11. GOA data from the GO Consortium
12. Gysemans CA, etal., Endocrinology. 2005 Apr;146(4):1956-64. Epub 2005 Jan 6.
13. Hagau N, etal., Crit Care. 2010;14(6):R203. Epub 2010 Nov 9.
14. Hirose K, etal., Infect Immun. 1998 Dec;66(12):5677-83.
15. Hocke AC, etal., Cytokine. 2007 May;38(2):61-73. Epub 2007 Jul 3.
16. Ishimitsu R, etal., J Immunol. 2001 Feb 1;166(3):1991-2001.
17. Iwasaki S, etal., Pediatr Res. 2007 Oct;62(4):392-8.
18. Kaibe M, etal., Am J Hypertens. 2005 Aug;18(8):1019-25.
19. Kamei K, etal., Eur Surg Res. 2010;44(3-4):159-69. Epub 2010 Mar 24.
20. Kimura K, etal., Cancer Immunol Immunother. 2000 May;49(2):71-7.
21. Koulmanda M, etal., Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13074-9. Epub 2007 Aug 1.
22. Kuczynski S, etal., Diabetes Res Clin Pract. 2005 Sep;69(3):231-6. Epub 2005 Mar 31.
23. Kuniyasu H, etal., Clin Cancer Res 2003 Oct 15;9(13):4802-10.
24. Kurz T, etal., J Allergy Clin Immunol. 2004 May;113(5):896-901.
25. Lacraz G, etal., PLoS One. 2016 Sep 29;11(9):e0162995. doi: 10.1371/journal.pone.0162995. eCollection 2016.
26. Leahy TR, etal., Eur Respir J. 2016 Jan;47(1):212-22. doi: 10.1183/13993003.00642-2015. Epub 2015 Nov 5.
27. Li Y, etal., Mol Oral Microbiol. 2010 Aug;25(4):275-92.
28. Marzetti E, etal., Mech Ageing Dev. 2009 Apr;130(4):272-80.
29. Maslinska D, etal., Folia Neuropathol. 2002;40(4):177-82.
30. McGill J, etal., J Exp Med. 2010 Mar 15;207(3):521-34. Epub 2010 Mar 8.
31. MGD data from the GO Consortium
32. Miyazaki S, etal., J Immunol. 2007 Oct 15;179(8):5407-14.
33. Muro S, etal., J Allergy Clin Immunol. 2001 Dec;108(6):970-5.
34. Nakamura R, etal., J Virol. 2010 Jun;84(11):5574-82. Epub 2010 Mar 24.
35. NCBI rat LocusLink and RefSeq merged data July 26, 2002
36. Nielsen AR, etal., J Clin Endocrinol Metab. 2008 Nov;93(11):4486-93. Epub 2008 Aug 12.
37. Piirila PL, etal., Allergy. 2008 May;63(5):583-91.
38. Pinto LA, etal., Allergy. 2009 Apr;64(4):643-6. Epub 2008 Dec 24.
39. Pipeline to import KEGG annotations from KEGG into RGD
40. Pistilli EE, etal., Am J Physiol Cell Physiol. 2007 Apr;292(4):C1298-304. Epub 2006 Nov 29.
41. Poon LL, etal., J Immunol. 2009 Mar 1;182(5):3063-71.
42. Qaisar N, etal., Diabetes. 2017 Jan;66(1):145-157. doi: 10.2337/db16-0462. Epub 2016 Oct 7.
43. Ramana Rao PV, etal., J Interferon Cytokine Res. 2010 Jan;30(1):33-42.
44. Reinecker HC, etal., Gastroenterology. 1996 Dec;111(6):1706-13.
45. Renaud SJ, etal., Biol Reprod. 2017 Jan 1;96(1):145-158. doi: 10.1095/biolreprod.116.142752.
46. RGD automated import pipeline for gene-chemical interactions
47. RGD comprehensive gene curation
48. Rothe H, etal., Horm Metab Res. 2002 Jan;34(1):7-12.
49. Ruckert R, etal., J Immunol. 2005 May 1;174(9):5507-15.
50. Sambatakou H, etal., Int J Immunogenet. 2006 Aug;33(4):297-302.
51. Small CL, etal., J Immunol. 2008 Apr 15;180(8):5558-68.
52. Sparmann G, etal., Am J Physiol Gastrointest Liver Physiol. 2005 Nov;289(5):G842-51. Epub 2005 Jul 7.
53. Stegall T and Krolick KA, J Neuroimmunol. 2001 Oct 1;119(2):377-86.
54. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
55. Verbist KC, etal., J Immunol. 2011 Jan 1;186(1):174-82. Epub 2010 Nov 22.
56. Wallstrom J, etal., Immunol Lett 2003 Aug 5;88(2):141-5.
57. Wang D, etal., Mol Immunol. 2010 Apr;47(7-8):1535-43. Epub 2010 Feb 25.
58. Wang WL, etal., J Gastroenterol Hepatol. 2007 Jul;22(7):1141-7. Epub 2007 May 27.
59. Wuttge DM, etal., Am J Pathol. 2001 Aug;159(2):417-23.
60. Wuttge DM, etal., Arthritis Res Ther. 2007;9(5):R85.
Additional References at PubMed
PMID:10704459   PMID:11737071   PMID:12244150   PMID:12477932   PMID:14607906   PMID:15123770   PMID:16405651   PMID:16482511   PMID:17318811   PMID:18239634   PMID:19747902   PMID:20450731  
PMID:23017227   PMID:24006180   PMID:24509081   PMID:24942581   PMID:25522723   PMID:29097254  


Genomics

Comparative Map Data
Il15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21925,640,013 - 25,706,818 (+)NCBI
Rnor_6.0 Ensembl1923,542,889 - 23,554,594 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01923,542,606 - 23,624,366 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01934,532,033 - 34,598,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41927,487,268 - 27,498,973 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11927,437,760 - 27,504,081 (+)NCBI
Celera1925,174,648 - 25,228,568 (+)NCBICelera
Celera1925,228,574 - 25,240,279 (+)NCBICelera
Cytogenetic Map19q11NCBI
IL15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4141,636,583 - 141,733,987 (+)EnsemblGRCh38hg38GRCh38
GRCh384141,636,583 - 141,733,987 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374142,557,736 - 142,655,140 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364142,777,204 - 142,874,062 (+)NCBINCBI36hg18NCBI36
Build 344142,997,904 - 143,012,216NCBI
Celera4139,888,493 - 139,985,377 (+)NCBI
Cytogenetic Map4q31.21NCBI
HuRef4138,287,515 - 138,384,970 (+)NCBIHuRef
CHM1_14142,535,127 - 142,632,588 (+)NCBICHM1_1
Il15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39883,058,253 - 83,129,883 (-)NCBIGRCm39mm39
GRCm39 Ensembl883,058,261 - 83,129,851 (-)Ensembl
GRCm38882,331,624 - 82,403,252 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl882,331,632 - 82,403,222 (-)EnsemblGRCm38mm10GRCm38
MGSCv37884,855,523 - 84,926,444 (-)NCBIGRCm37mm9NCBIm37
MGSCv36885,227,371 - 85,298,292 (-)NCBImm8
Celera886,620,550 - 86,691,831 (-)NCBICelera
Cytogenetic Map8C2NCBI
cM Map839.33NCBI
Il15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554711,497,483 - 1,511,469 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554711,496,352 - 1,583,919 (-)NCBIChiLan1.0ChiLan1.0
IL15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14145,307,339 - 145,416,622 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4145,402,111 - 145,416,622 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04133,693,995 - 134,115,470 (+)NCBIMhudiblu_PPA_v0panPan3
IL15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1191,339,607 - 1,364,762 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl191,339,967 - 1,364,762 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha191,586,489 - 1,611,118 (-)NCBI
ROS_Cfam_1.0191,361,003 - 1,425,159 (-)NCBI
UMICH_Zoey_3.1191,341,699 - 1,366,271 (-)NCBI
UNSW_CanFamBas_1.0191,703,298 - 1,727,862 (-)NCBI
UU_Cfam_GSD_1.0192,058,426 - 2,083,219 (-)NCBI
Il15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530148,906,307 - 48,919,895 (-)NCBI
SpeTri2.0NW_0049365356,344,348 - 6,358,803 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl885,667,307 - 85,740,911 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1885,666,963 - 85,740,980 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2890,963,736 - 91,036,632 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1788,548,773 - 88,644,977 (+)NCBI
ChlSab1.1 Ensembl788,548,671 - 88,645,488 (+)Ensembl
Vero_WHO_p1.0NW_02366603768,097,083 - 68,194,427 (+)NCBI
Il15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248531,059,625 - 1,144,799 (+)NCBI

Position Markers
D19Rat12  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21925,704,671 - 25,704,884 (-)MAPPER
Rnor_6.01923,544,543 - 23,544,753NCBIRnor6.0
Rnor_5.01934,533,970 - 34,534,180UniSTSRnor5.0
RGSC_v3.41927,497,108 - 27,497,319RGDRGSC3.4
RGSC_v3.41927,497,109 - 27,497,319UniSTSRGSC3.4
RGSC_v3.11927,501,934 - 27,502,145RGD
Celera1925,238,415 - 25,238,625UniSTS
SHRSP x BN Map1920.2599UniSTS
SHRSP x BN Map1920.2599RGD
FHH x ACI Map1921.16RGD
Cytogenetic Map19q11UniSTS
RH127909  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21925,706,452 - 25,706,655 (-)MAPPER
Rnor_6.01923,542,772 - 23,542,974NCBIRnor6.0
Rnor_5.01934,532,199 - 34,532,401UniSTSRnor5.0
RGSC_v3.41927,498,888 - 27,499,090UniSTSRGSC3.4
Celera1925,240,194 - 25,240,396UniSTS
Cytogenetic Map19q11UniSTS
RH94635  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21925,706,622 - 25,706,804 (-)MAPPER
Rnor_6.01923,542,623 - 23,542,804NCBIRnor6.0
Rnor_5.01934,532,050 - 34,532,231UniSTSRnor5.0
RGSC_v3.41927,499,058 - 27,499,239UniSTSRGSC3.4
Celera1925,240,364 - 25,240,545UniSTS
Cytogenetic Map19q11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124933090Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127635288Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19129558305Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19129558305Rat
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19132379055Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19138221845Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19138221845Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19138221845Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19138221845Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19104464846044648Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19195770746957707Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19243296347217667Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19243296362275575Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)19370183548701835Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)19370183548701835Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19500757143907843Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19650676160220581Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19807254547318201Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191073992926201726Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191130392747879277Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191529452433991703Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191593952838798459Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191702800352538299Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191899398262275575Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191917749562275575Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)192140778762275575Rat


Related Rat Strains
The following Strains have been annotated to Il15


Genetic Models
This gene Il15 is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:279
Count of miRNA genes:184
Interacting mature miRNAs:219
Transcripts:ENSRNOT00000004590
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 9 9 1 19 1 4 7 25 21 11 4
Low 34 48 40 40 4 4 70 10 20 4
Below cutoff 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_013129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008774216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008774217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF015718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF015719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC097340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U69272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000004590   ⟹   ENSRNOP00000004590
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1923,542,889 - 23,554,594 (-)Ensembl
RefSeq Acc Id: NM_013129   ⟹   NP_037261
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,694,831 - 25,706,538 (+)NCBI
Rnor_6.01923,542,889 - 23,554,594 (-)NCBI
Rnor_5.01934,532,033 - 34,598,725 (-)NCBI
RGSC_v3.41927,487,268 - 27,498,973 (+)RGD
Celera1925,228,574 - 25,240,279 (+)RGD
Sequence:
RefSeq Acc Id: XM_008772363   ⟹   XP_008770585
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01923,542,606 - 23,610,035 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008772423   ⟹   XP_008770645
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01923,554,600 - 23,610,050 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008772424   ⟹   XP_008770646
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,428 - 25,694,810 (+)NCBI
Rnor_6.01923,554,603 - 23,610,053 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008774216   ⟹   XP_008772438
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1925,174,651 - 25,228,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008774217   ⟹   XP_008772439
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1925,174,648 - 25,228,565 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601185   ⟹   XP_017456674
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01923,542,606 - 23,610,033 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601186   ⟹   XP_017456675
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,081 - 25,706,818 (+)NCBI
Rnor_6.01923,542,606 - 23,610,033 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601187   ⟹   XP_017456676
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,081 - 25,706,818 (+)NCBI
Rnor_6.01923,542,606 - 23,610,033 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601188   ⟹   XP_017456677
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01923,542,606 - 23,624,366 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601189   ⟹   XP_017456678
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01923,542,606 - 23,558,281 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601190   ⟹   XP_017456679
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,013 - 25,668,959 (+)NCBI
Rnor_6.01923,583,944 - 23,610,050 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097502   ⟹   XP_038953430
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,428 - 25,692,544 (+)NCBI
RefSeq Acc Id: XM_039097503   ⟹   XP_038953431
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,428 - 25,669,137 (+)NCBI
RefSeq Acc Id: XM_039097504   ⟹   XP_038953432
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,428 - 25,668,959 (+)NCBI
RefSeq Acc Id: XM_039097505   ⟹   XP_038953433
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,428 - 25,688,491 (+)NCBI
RefSeq Acc Id: XM_039097506   ⟹   XP_038953434
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,015 - 25,694,765 (+)NCBI
RefSeq Acc Id: XM_039097507   ⟹   XP_038953435
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,025 - 25,694,810 (+)NCBI
RefSeq Acc Id: XM_039097508   ⟹   XP_038953436
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,081 - 25,706,818 (+)NCBI
RefSeq Acc Id: XM_039097509   ⟹   XP_038953437
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,079 - 25,706,818 (+)NCBI
RefSeq Acc Id: XM_039097510   ⟹   XP_038953438
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,079 - 25,706,818 (+)NCBI
RefSeq Acc Id: XM_039097511   ⟹   XP_038953439
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,674,718 - 25,706,818 (+)NCBI
RefSeq Acc Id: XM_039097512   ⟹   XP_038953440
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,080 - 25,706,818 (+)NCBI
RefSeq Acc Id: XM_039097513   ⟹   XP_038953441
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,080 - 25,706,818 (+)NCBI
RefSeq Acc Id: XM_039097514   ⟹   XP_038953442
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,080 - 25,706,818 (+)NCBI
RefSeq Acc Id: XM_039097515   ⟹   XP_038953443
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,079 - 25,706,818 (+)NCBI
RefSeq Acc Id: XM_039097516   ⟹   XP_038953444
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,079 - 25,706,818 (+)NCBI
RefSeq Acc Id: XM_039097517   ⟹   XP_038953445
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,079 - 25,706,818 (+)NCBI
RefSeq Acc Id: XM_039097518   ⟹   XP_038953446
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,016 - 25,669,137 (+)NCBI
RefSeq Acc Id: XM_039097519   ⟹   XP_038953447
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,015 - 25,694,803 (+)NCBI
RefSeq Acc Id: XM_039097520   ⟹   XP_038953448
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21925,640,072 - 25,706,818 (+)NCBI
Protein Sequences
Protein RefSeqs NP_037261 (Get FASTA)   NCBI Sequence Viewer  
  XP_008770646 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456675 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456676 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456679 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953430 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953431 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953432 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953433 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953434 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953435 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953436 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953437 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953438 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953439 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953440 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953441 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953442 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953443 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953444 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953445 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953446 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953447 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953448 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB41697 (Get FASTA)   NCBI Sequence Viewer  
  AAB94535 (Get FASTA)   NCBI Sequence Viewer  
  AAB94536 (Get FASTA)   NCBI Sequence Viewer  
  EDL92290 (Get FASTA)   NCBI Sequence Viewer  
  EDL92291 (Get FASTA)   NCBI Sequence Viewer  
  P97604 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_037261   ⟸   NM_013129
- Peptide Label: precursor
- UniProtKB: P97604 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008770585   ⟸   XM_008772363
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008772439   ⟸   XM_008774217
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008772438   ⟸   XM_008774216
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456677   ⟸   XM_017601188
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017456676   ⟸   XM_017601187
- Peptide Label: isoform X6
- UniProtKB: P97604 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017456675   ⟸   XM_017601186
- Peptide Label: isoform X6
- UniProtKB: P97604 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017456674   ⟸   XM_017601185
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017456678   ⟸   XM_017601189
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008770645   ⟸   XM_008772423
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008770646   ⟸   XM_008772424
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017456679   ⟸   XM_017601190
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000004590   ⟸   ENSRNOT00000004590
RefSeq Acc Id: XP_038953447   ⟸   XM_039097519
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038953434   ⟸   XM_039097506
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038953446   ⟸   XM_039097518
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038953435   ⟸   XM_039097507
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038953448   ⟸   XM_039097520
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038953438   ⟸   XM_039097510
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953437   ⟸   XM_039097509
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953443   ⟸   XM_039097515
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953444   ⟸   XM_039097516
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953445   ⟸   XM_039097517
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953440   ⟸   XM_039097512
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953441   ⟸   XM_039097513
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953442   ⟸   XM_039097514
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953436   ⟸   XM_039097508
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953430   ⟸   XM_039097502
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953433   ⟸   XM_039097505
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953431   ⟸   XM_039097503
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953432   ⟸   XM_039097504
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953439   ⟸   XM_039097511
- Peptide Label: isoform X6

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2887 AgrOrtholog
Ensembl Genes ENSRNOG00000003439 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000004590 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000004590 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1250.70 UniProtKB/Swiss-Prot
InterPro 4_helix_cytokine-like_core UniProtKB/Swiss-Prot
  IL-15 UniProtKB/Swiss-Prot
  IL-15/IL-21_fam UniProtKB/Swiss-Prot
  IL-15/IL-21_sf UniProtKB/Swiss-Prot
  IL-15_mml UniProtKB/Swiss-Prot
KEGG Report rno:25670 UniProtKB/Swiss-Prot
NCBI Gene 25670 ENTREZGENE
PANTHER PTHR14356 UniProtKB/Swiss-Prot
Pfam IL15 UniProtKB/Swiss-Prot
PhenoGen Il15 PhenoGen
PRINTS INTLKN15MAML UniProtKB/Swiss-Prot
  INTRLEUKIN15 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47266 UniProtKB/Swiss-Prot
TIGR TC221104
UniProt IL15_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary O54847 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Il15  Interleukin 15      Symbol and Name status set to approved 70586 APPROVED