IL15 (interleukin 15) - Rat Genome Database

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Gene: IL15 (interleukin 15) Canis lupus familiaris
Analyze
Symbol: IL15
Name: interleukin 15
RGD ID: 12420146
Description: ENCODES a protein that exhibits cytokine activity (inferred); cytokine receptor binding (inferred); INVOLVED IN cell maturation (ortholog); cellular response to vitamin D (ortholog); extrathymic T cell selection (ortholog); PARTICIPATES IN Jak-Stat signaling pathway; ASSOCIATED WITH adult respiratory distress syndrome (ortholog); arteriosclerosis (ortholog); aspergillosis (ortholog); FOUND IN cell surface (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: interleukin-15
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1191,339,607 - 1,364,762 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl191,339,967 - 1,364,762 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha191,586,489 - 1,611,118 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0191,361,003 - 1,425,159 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl191,361,363 - 1,373,768 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1191,341,699 - 1,366,271 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0191,703,298 - 1,727,862 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0192,058,426 - 2,083,219 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22014415   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
IL15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1191,339,607 - 1,364,762 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl191,339,967 - 1,364,762 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha191,586,489 - 1,611,118 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0191,361,003 - 1,425,159 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl191,361,363 - 1,373,768 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1191,341,699 - 1,366,271 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0191,703,298 - 1,727,862 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0192,058,426 - 2,083,219 (-)NCBIUU_Cfam_GSD_1.0
IL15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384141,636,583 - 141,733,987 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4141,636,583 - 141,733,987 (+)EnsemblGRCh38hg38GRCh38
GRCh374142,557,736 - 142,655,140 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364142,777,204 - 142,874,062 (+)NCBINCBI36Build 36hg18NCBI36
Build 344142,997,904 - 143,012,216NCBI
Celera4139,888,493 - 139,985,377 (+)NCBICelera
Cytogenetic Map4q31.21NCBI
HuRef4138,287,515 - 138,384,970 (+)NCBIHuRef
CHM1_14142,535,127 - 142,632,588 (+)NCBICHM1_1
T2T-CHM13v2.04144,953,939 - 145,051,309 (+)NCBIT2T-CHM13v2.0
Il15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39883,058,253 - 83,129,883 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl883,058,261 - 83,129,851 (-)EnsemblGRCm39 Ensembl
GRCm38882,331,624 - 82,403,252 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl882,331,632 - 82,403,222 (-)EnsemblGRCm38mm10GRCm38
MGSCv37884,855,523 - 84,926,444 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36885,227,371 - 85,298,292 (-)NCBIMGSCv36mm8
Celera886,620,550 - 86,691,831 (-)NCBICelera
Cytogenetic Map8C2NCBI
cM Map839.33NCBI
Il15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81942,536,160 - 42,611,349 (+)NCBIGRCr8
mRatBN7.21925,640,025 - 25,706,818 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1925,640,251 - 25,706,820 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1932,488,865 - 32,555,378 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01933,142,935 - 33,209,458 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01935,364,627 - 35,431,235 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01923,542,606 - 23,624,366 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1923,542,889 - 23,554,594 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01934,532,033 - 34,598,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41927,487,268 - 27,498,973 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11927,437,760 - 27,504,081 (+)NCBI
Celera1925,228,574 - 25,240,279 (+)NCBICelera
Celera1925,174,648 - 25,228,568 (+)NCBICelera
Cytogenetic Map19q11NCBI
Il15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554711,497,483 - 1,511,469 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554711,496,352 - 1,583,919 (-)NCBIChiLan1.0ChiLan1.0
IL15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23139,519,329 - 139,630,011 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14139,907,214 - 140,017,980 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04133,693,995 - 134,115,470 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14145,307,339 - 145,416,622 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4145,402,111 - 145,416,622 (+)Ensemblpanpan1.1panPan2
Il15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530148,906,307 - 48,919,895 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365356,344,395 - 6,350,197 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365356,344,348 - 6,358,803 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl885,667,321 - 85,678,461 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1885,666,963 - 85,740,980 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2890,963,736 - 91,036,632 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1788,548,773 - 88,644,977 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl788,548,671 - 88,645,488 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603768,097,083 - 68,194,427 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248531,128,519 - 1,144,941 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248531,059,625 - 1,144,799 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IL15
372 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 5
Low 5 5 22 6 5 6 6 6 12 5 6
Below cutoff 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000005832   ⟹   ENSCAFP00000005401
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl191,339,967 - 1,364,762 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000059552   ⟹   ENSCAFP00000057455
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl191,339,967 - 1,350,416 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845034691   ⟹   ENSCAFP00845027171
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl191,361,363 - 1,371,814 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845034752   ⟹   ENSCAFP00845027216
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl191,361,526 - 1,373,768 (-)Ensembl
RefSeq Acc Id: NM_001197188   ⟹   NP_001184117
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1191,339,967 - 1,364,762 (-)NCBI
Dog10K_Boxer_Tasha191,586,489 - 1,611,118 (-)NCBI
ROS_Cfam_1.0191,361,362 - 1,386,161 (-)NCBI
UMICH_Zoey_3.1191,341,699 - 1,366,271 (-)NCBI
UNSW_CanFamBas_1.0191,703,298 - 1,727,862 (-)NCBI
UU_Cfam_GSD_1.0192,058,426 - 2,083,219 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038425560   ⟹   XP_038281488
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0191,361,003 - 1,425,159 (-)NCBI
RefSeq Acc Id: XM_038425561   ⟹   XP_038281489
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0191,361,003 - 1,425,132 (-)NCBI
RefSeq Acc Id: XM_038425562   ⟹   XP_038281490
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0191,361,003 - 1,401,800 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001184117   ⟸   NM_001197188
- UniProtKB: A0A8C0NA66 (UniProtKB/TrEMBL),   A0A8C0L9P6 (UniProtKB/TrEMBL),   A0A8P0S9D1 (UniProtKB/TrEMBL),   A0A8C0L9N7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000005401   ⟸   ENSCAFT00000005832
RefSeq Acc Id: ENSCAFP00000057455   ⟸   ENSCAFT00000059552
RefSeq Acc Id: XP_038281488   ⟸   XM_038425560
- Peptide Label: isoform X1
- UniProtKB: A0A8I3S443 (UniProtKB/TrEMBL),   A0A8C0L9N7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038281489   ⟸   XM_038425561
- Peptide Label: isoform X1
- UniProtKB: A0A8I3S443 (UniProtKB/TrEMBL),   A0A8C0L9N7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038281490   ⟸   XM_038425562
- Peptide Label: isoform X1
- UniProtKB: A0A8I3S443 (UniProtKB/TrEMBL),   A0A8C0L9N7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845027216   ⟸   ENSCAFT00845034752
RefSeq Acc Id: ENSCAFP00845027171   ⟸   ENSCAFT00845034691


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003626 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030014833 UniProtKB/TrEMBL
  ENSCAFG00040007556 UniProtKB/TrEMBL
  ENSCAFG00845019627 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000005832.5 UniProtKB/TrEMBL
  ENSCAFT00000059552.2 UniProtKB/TrEMBL
  ENSCAFT00030027459.1 UniProtKB/TrEMBL
  ENSCAFT00030027520.1 UniProtKB/TrEMBL
  ENSCAFT00040014105.1 UniProtKB/TrEMBL
  ENSCAFT00040014136.1 UniProtKB/TrEMBL
  ENSCAFT00845034691.1 UniProtKB/TrEMBL
  ENSCAFT00845034752 ENTREZGENE
  ENSCAFT00845034752.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.70 UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/TrEMBL
  IL-15 UniProtKB/TrEMBL
  IL-15/IL-21_fam UniProtKB/TrEMBL
  IL-15_mml UniProtKB/TrEMBL
KEGG Report cfa:403584 UniProtKB/TrEMBL
NCBI Gene IL15 ENTREZGENE
PANTHER INTERLEUKIN-15 UniProtKB/TrEMBL
  PTHR14356 UniProtKB/TrEMBL
Pfam IL15 UniProtKB/TrEMBL
PRINTS INTLKN15MAML UniProtKB/TrEMBL
  INTRLEUKIN15 UniProtKB/TrEMBL
Superfamily-SCOP SSF47266 UniProtKB/TrEMBL
UniProt A0A8C0L9N7 ENTREZGENE
  A0A8C0L9P6 ENTREZGENE
  A0A8C0NA66 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0NFN3_CANLF UniProtKB/TrEMBL
  A0A8I3NZC3_CANLF UniProtKB/TrEMBL
  A0A8I3S443 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0S9D1 ENTREZGENE
UniProt Secondary A0A8P0S9D1 UniProtKB/TrEMBL
  A0A8P0T9K3 UniProtKB/TrEMBL
VGNC ID VGNC:41939 ENTREZGENE