Ndrg4 (NDRG family member 4) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ndrg4 (NDRG family member 4) Rattus norvegicus
Analyze
Symbol: Ndrg4
Name: NDRG family member 4
RGD ID: 621593
Description: Involved in brain development; positive regulation of ERK1 and ERK2 cascade; and positive regulation of neuron projection development. Located in endoplasmic reticulum membrane and mitochondrion. Orthologous to human NDRG4 (NDRG family member 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; Allylamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AF045564; Bdm1; brain development-related molecule 1; development-related protein; N-myc downstream regulated 4; N-myc downstream regulated gene 4; Ndr4; smap8
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2199,351,408 - 9,387,398 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl199,351,404 - 9,386,914 (-)Ensembl
Rnor_6.0199,766,439 - 9,802,396 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,766,439 - 9,801,942 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0199,751,517 - 9,787,463 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4199,808,017 - 9,818,974 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1199,812,842 - 9,823,800 (-)NCBI
Celera199,246,398 - 9,281,901 (-)NCBICelera
Cytogenetic Map19p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(2,4,5-trichlorophenoxy)acetic acid  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
Allylamine  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
diethyl phthalate  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
glycine betaine  (EXP)
indometacin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
methapyrilene  (ISO)
nickel atom  (ISO)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
progesterone  (EXP)
propanal  (ISO)
raloxifene  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
taurine  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
troglitazone  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
WIN 55212-2  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. NDRG4 is downregulated in glioblastoma and inhibits cell proliferation. Ding W, etal., OMICS. 2012 May;16(5):263-7. doi: 10.1089/omi.2011.0146. Epub 2012 Apr 10.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Ndrg4 enhances NGF-induced ERK activation uncoupled with Elk-1 activation. Hongo S, etal., J Cell Biochem. 2006 May 1;98(1):185-93.
4. Downregulation of N-Myc downstream-regulated gene 4 influences patient survival in gliomas. Li S, etal., Brain Tumor Pathol. 2013 Jan;30(1):8-14. doi: 10.1007/s10014-012-0092-2. Epub 2012 Mar 8.
5. Molecular characterization of NDRG4/Bdm1 protein isoforms that are differentially regulated during rat brain development. Nakada N, etal., Brain Res Dev Brain Res 2002 Apr 30;135(1-2):45-53.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. A novel homocysteine-responsive gene, smap8, modulates mitogenesis in rat vascular smooth muscle cells. Nishimoto S, etal., Eur J Biochem 2003 Jun;270(11):2521-31.
8. Inhibition of neurite outgrowth by reduced level of NDRG4 protein in antisense transfected PC12 cells. Ohki T, etal., Brain Res Dev Brain Res 2002 Apr 30;135(1-2):55-63.
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. NDRG4 protein-deficient mice exhibit spatial learning deficits and vulnerabilities to cerebral ischemia. Yamamoto H, etal., J Biol Chem. 2011 Jul 22;286(29):26158-65. doi: 10.1074/jbc.M111.256446. Epub 2011 Jun 2.
13. Molecular cloning and characterization of a novel developmentally regulated gene, Bdm1, showing predominant expression in postnatal rat brain. Yamauchi Y, etal., Brain Res Mol Brain Res 1999 May 7;68(1-2):149-58.
Additional References at PubMed
PMID:14693380   PMID:17465030   PMID:17998568   PMID:19193716   PMID:19535783   PMID:24048452   PMID:26780215   PMID:30593880   PMID:32048632   PMID:35126626  


Genomics

Comparative Map Data
Ndrg4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2199,351,408 - 9,387,398 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl199,351,404 - 9,386,914 (-)Ensembl
Rnor_6.0199,766,439 - 9,802,396 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,766,439 - 9,801,942 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0199,751,517 - 9,787,463 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4199,808,017 - 9,818,974 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1199,812,842 - 9,823,800 (-)NCBI
Celera199,246,398 - 9,281,901 (-)NCBICelera
Cytogenetic Map19p13NCBI
NDRG4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381658,463,715 - 58,515,387 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1658,462,846 - 58,513,628 (+)EnsemblGRCh38hg38GRCh38
GRCh371658,497,619 - 58,547,523 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361657,055,118 - 57,105,024 (+)NCBINCBI36hg18NCBI36
Build 341657,079,160 - 57,105,023NCBI
Celera1642,996,552 - 43,046,481 (+)NCBI
Cytogenetic Map16q21NCBI
HuRef1644,366,336 - 44,415,505 (+)NCBIHuRef
CHM1_11659,904,745 - 59,954,713 (+)NCBICHM1_1
T2T-CHM13v2.01664,258,952 - 64,308,852 (+)NCBI
Ndrg4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39896,403,602 - 96,441,584 (+)NCBIGRCm39mm39
GRCm39 Ensembl896,403,608 - 96,441,747 (+)Ensembl
GRCm38895,676,974 - 95,714,956 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl895,676,980 - 95,715,119 (+)EnsemblGRCm38mm10GRCm38
MGSCv37898,226,963 - 98,238,856 (+)NCBIGRCm37mm9NCBIm37
MGSCv36898,592,192 - 98,604,085 (+)NCBImm8
Celera8100,013,817 - 100,025,880 (+)NCBICelera
Cytogenetic Map8D1NCBI
Ndrg4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543315,914,823 - 15,933,659 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543315,914,884 - 15,933,000 (+)NCBIChiLan1.0ChiLan1.0
NDRG4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11657,857,414 - 57,907,557 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1657,857,414 - 57,907,557 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01638,729,616 - 38,780,173 (+)NCBIMhudiblu_PPA_v0panPan3
NDRG4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1258,144,113 - 58,160,885 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl258,144,105 - 58,183,470 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha254,774,500 - 54,814,175 (-)NCBI
ROS_Cfam_1.0258,682,946 - 58,722,669 (-)NCBI
ROS_Cfam_1.0 Ensembl258,682,172 - 58,722,648 (-)Ensembl
UMICH_Zoey_3.1255,512,573 - 55,552,254 (-)NCBI
UNSW_CanFamBas_1.0256,519,817 - 56,560,052 (-)NCBI
UU_Cfam_GSD_1.0257,414,873 - 57,454,588 (-)NCBI
Ndrg4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934949,292,489 - 49,334,543 (-)NCBI
SpeTri2.0NW_00493647510,254,511 - 10,296,593 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDRG4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl620,223,871 - 20,265,577 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1620,222,876 - 20,265,581 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2618,283,793 - 18,326,496 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NDRG4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1544,402,021 - 44,452,829 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl544,402,453 - 44,455,245 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604731,718,955 - 31,769,835 (-)NCBIVero_WHO_p1.0
Ndrg4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474627,763,055 - 27,802,729 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462474627,763,055 - 27,803,622 (-)NCBIHetGla_female_1.0hetGla2


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:654
Count of miRNA genes:197
Interacting mature miRNAs:231
Transcripts:ENSRNOT00000017413, ENSRNOT00000017494, ENSRNOT00000051414
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 10
Medium 1 43 3 62 35 34 2
Low 2 35 22 19 22 8 11 2 7 9 8
Below cutoff 19 19 19

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001271091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006255123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF045564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF524894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH013091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY217029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY217030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY217031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY217032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY217033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY255791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB585874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB713901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM054107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000017413   ⟹   ENSRNOP00000017413
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,351,404 - 9,362,435 (-)Ensembl
Rnor_6.0 Ensembl199,766,439 - 9,777,465 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000017494   ⟹   ENSRNOP00000017494
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,351,408 - 9,386,914 (-)Ensembl
Rnor_6.0 Ensembl199,766,439 - 9,801,942 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000051414   ⟹   ENSRNOP00000044520
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,351,408 - 9,386,914 (-)Ensembl
Rnor_6.0 Ensembl199,766,439 - 9,801,942 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110322   ⟹   ENSRNOP00000091492
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,351,408 - 9,369,546 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000115384   ⟹   ENSRNOP00000079935
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,351,408 - 9,386,914 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116737   ⟹   ENSRNOP00000084746
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,351,414 - 9,362,394 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117717   ⟹   ENSRNOP00000082556
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,351,545 - 9,362,403 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119566   ⟹   ENSRNOP00000085740
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,351,430 - 9,369,546 (-)Ensembl
RefSeq Acc Id: NM_001271091   ⟹   NP_001258020
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2199,351,408 - 9,386,914 (-)NCBI
Rnor_6.0199,766,439 - 9,801,942 (-)NCBI
Rnor_5.0199,751,517 - 9,787,463 (-)NCBI
Celera199,246,398 - 9,281,901 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001271092   ⟹   NP_001258021
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2199,351,408 - 9,386,914 (-)NCBI
Rnor_6.0199,766,439 - 9,801,942 (-)NCBI
Rnor_5.0199,751,517 - 9,787,463 (-)NCBI
Celera199,246,398 - 9,281,901 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001271093   ⟹   NP_001258022
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2199,351,408 - 9,374,234 (-)NCBI
Rnor_6.0199,766,439 - 9,789,263 (-)NCBI
Rnor_5.0199,751,517 - 9,787,463 (-)NCBI
Celera199,246,398 - 9,269,222 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001271094   ⟹   NP_001258023
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2199,351,408 - 9,374,234 (-)NCBI
Rnor_6.0199,766,439 - 9,789,263 (-)NCBI
Rnor_5.0199,751,517 - 9,787,463 (-)NCBI
Celera199,246,398 - 9,269,222 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001271095   ⟹   NP_001258024
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2199,351,408 - 9,362,435 (-)NCBI
Rnor_6.0199,766,439 - 9,777,465 (-)NCBI
Rnor_5.0199,751,517 - 9,787,463 (-)NCBI
Celera199,246,398 - 9,257,424 (-)NCBI
Sequence:
RefSeq Acc Id: NM_031967   ⟹   NP_114173
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2199,351,408 - 9,362,435 (-)NCBI
Rnor_6.0199,766,439 - 9,777,465 (-)NCBI
Rnor_5.0199,751,517 - 9,787,463 (-)NCBI
RGSC_v3.4199,808,017 - 9,818,974 (-)RGD
Celera199,246,398 - 9,257,424 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006255123   ⟹   XP_006255185
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2199,351,408 - 9,387,398 (-)NCBI
Rnor_6.0199,766,439 - 9,802,396 (-)NCBI
Rnor_5.0199,751,517 - 9,787,463 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_114173   ⟸   NM_031967
- Peptide Label: isoform 5
- UniProtKB: G3V7P8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258021   ⟸   NM_001271092
- Peptide Label: isoform 2 precursor
- UniProtKB: D3Z831 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258020   ⟸   NM_001271091
- Peptide Label: isoform 1 precursor
- UniProtKB: D3ZUT8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258023   ⟸   NM_001271094
- Peptide Label: isoform 4
- Sequence:
RefSeq Acc Id: NP_001258022   ⟸   NM_001271093
- Peptide Label: isoform 3
- Sequence:
RefSeq Acc Id: NP_001258024   ⟸   NM_001271095
- Peptide Label: isoform 6
- Sequence:
RefSeq Acc Id: XP_006255185   ⟸   XM_006255123
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000044520   ⟸   ENSRNOT00000051414
RefSeq Acc Id: ENSRNOP00000017494   ⟸   ENSRNOT00000017494
RefSeq Acc Id: ENSRNOP00000017413   ⟸   ENSRNOT00000017413
RefSeq Acc Id: ENSRNOP00000082556   ⟸   ENSRNOT00000117717
RefSeq Acc Id: ENSRNOP00000079935   ⟸   ENSRNOT00000115384
RefSeq Acc Id: ENSRNOP00000091492   ⟸   ENSRNOT00000110322
RefSeq Acc Id: ENSRNOP00000084746   ⟸   ENSRNOT00000116737
RefSeq Acc Id: ENSRNOP00000085740   ⟸   ENSRNOT00000119566

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z2L9-F1-model_v2 AlphaFold Q9Z2L9 1-352 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700924
Promoter ID:EPDNEW_R11448
Type:single initiation site
Name:Ndrg4_1
Description:NDRG family member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0199,777,436 - 9,777,496EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
19 9773833 9773834 C T snv ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), ACI/N (MCW), F344/NRrrc (MCW), M520/N (MCW), MR/N (MCW), ACI/EurMcwi (RGD), BBDP/Wor (RGD), F344/NCrl (RGD), FHH/EurMcwi (RGD), LE/Stm (RGD), LEW/Crl (RGD), LEW/NCrlBR (RGD), LH/MavRrrc (RGD), LN/MavRrrc (RGD), LL/MavRrrc (RGD), MHS/Gib (RGD), SBH/Ygl (RGD), SBN/Ygl (RGD), SR/JrHsd (RGD), SS/Jr (RGD), SS/JrHsdMcwi (RGD), WAG/Rij (RGD), ACI/EurMcwi (2019), ACI/N (2020), DA/OlaHsd (2019), F344/DuCrl (2019), F344/NCrl (2019), F344/Stm (2019), FHH/EurMcwi (2019), FXLE16/Stm (2020), FXLE18/Stm (2020), LEW/Crl (2019), LEXF11/Stm (2020), LEXF1C/Stm (2019), LEXF4/Stm (2020), LE/Stm (2019), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), M520/N (2020), MR/N (2020), MWF/Hsd (2019), PVG/Seac (2019), SR/JrHsd (2020), SS/JrHsdMcwi (2019), WAG/RijCrl (2020), WN/N (2020), CDR, CDS, Buf/N (MCW), WN/N (MCW), FHL/EurMcwi (RGD), MNS/Gib (RGD), BUF/N (2020), F344/N (2020), LEXF1A/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LH/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
19 9758911 9758912 C T snv ACI/EurMcwi (MCW), ZFDM (KyushuU), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), WN/N (KNAW), LH/MavRrrc (KNAW), LL/MavRrrc (KNAW), LN/MavRrrc (KNAW), MHS/Gib (KNAW), MR/N (KNAW), SR/JrHsd (KNAW), SS/Jr (KNAW), SS/JrHsdMcwi (KNAW), WAG/Rij (KNAW), ACI/N (KNAW), ACI/EurMcwi (KNAW), BBDP/WorN (KNAW), BUF/N (KNAW), DA/BklArbNsi (KNAW), F344/NRrrc (SOLiD) (KNAW), F344/NCrl (KNAW), F344/NHsd (KNAW), FHH/EurMcwi (KNAW), FHL/EurMcwi (KNAW), LE/Stm (Illumina) (KNAW), LE/Stm (SOLiD) (KNAW), LEW/Crl (KNAW), LEW/NCrl (KNAW), M520/N (KNAW), MNS/Gib (KNAW), SBH/Ygl (KNAW), SBN/Ygl (KNAW), F344/NRrrc (Illumina) (KNAW), SDLEF7/Barth (UDEL), LE/OrlBarth (UDEL), Crl:SD (UDEL), IS/Kyo (KyushuU), NIG-III/Hok (KyushuU), F344/DuCrlCrlj (KyushuU), RCS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU), F344/Stm (KyushuU), HWY/Slc (KyushuU), LEC/Tj (KyushuU), BDIX/NemOda (KyushuU), KFRS3B/Kyo (KyushuU), ZF (KyushuU), COP/CrCrl (MCW & UW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
19 9815410 9815411 C T snv ACI/EurMcwi (MCW), F344/NHsd (ICAHN), FHL/EurMcwi (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), FHH/EurMcwi (MDC), SS/JrHsdMcwi (MDC), ACI/N (KNAW), BUF/N (KNAW), F344/NRrrc (KNAW), M520/N (KNAW), MR/N (KNAW), WN/N (KNAW), COP/CrCrl (MCW & UW), GH/OmrMcwi (MCW), ACI/EurMcwi (ICL), BBDP/WorN (ICL), F344/NCrl (ICL), FHH/EurMcwi (ICL), FHL/EurMcwi (ICL), LE/Stm (ICL), LEW/Crl (ICL), LEW/NCrl (ICL), LH/MavRrrc (ICL), LL/MavRrrc (ICL), LN/MavRrrc (ICL), MHS/Gib (ICL), MNS/Gib (ICL), SBH/Ygl (ICL), SBN/Ygl (ICL), SR/JrHsd (ICL), SS/Jr (ICL), SS/JrHsdMcwi (ICL), WAG/Rij (ICL), HCR/1Mco (UMich), LCR/1Mco (UMich), HCR/2Mco (UMich), LCR/2Mco (UMich), DA/BklArbNsi (ICAHN), FHH/EurMcwi (MCW)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
19 9358803 9358804 C T snv ACI/EurMcwi (2019), WN/N (2020), BUF/N (2020), DA/OlaHsd (2019), F344/DuCrl (2019), F344/NCrl (2019), F344/N (2020), F344/Stm (2019), FHH/EurMcwi (2019), FXLE16/Stm (2020), FXLE18/Stm (2020), LEW/Crl (2019), LEXF11/Stm (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LEXF4/Stm (2020), LE/Stm (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019), M520/N (2020), MR/N (2020), MWF/Hsd (2019), PVG/Seac (2019), SR/JrHsd (2020), SS/JrHsdMcwi (2019), WAG/RijCrl (2020), ACI/N (2020)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621593 AgrOrtholog
BioCyc Gene G2FUF-6544 BioCyc
Ensembl Genes ENSRNOG00000012482 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000017413 ENTREZGENE
  ENSRNOP00000017413.5 UniProtKB/TrEMBL
  ENSRNOP00000017494 ENTREZGENE
  ENSRNOP00000017494.4 UniProtKB/TrEMBL
  ENSRNOP00000044520 ENTREZGENE
  ENSRNOP00000044520.2 UniProtKB/TrEMBL
  ENSRNOP00000079935.1 UniProtKB/TrEMBL
  ENSRNOP00000082556.1 UniProtKB/TrEMBL
  ENSRNOP00000084746 ENTREZGENE
  ENSRNOP00000084746.1 UniProtKB/TrEMBL
  ENSRNOP00000085740 ENTREZGENE
  ENSRNOP00000085740.1 UniProtKB/TrEMBL
  ENSRNOP00000091492 ENTREZGENE
  ENSRNOP00000091492.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017413 ENTREZGENE
  ENSRNOT00000017413.7 UniProtKB/TrEMBL
  ENSRNOT00000017494 ENTREZGENE
  ENSRNOT00000017494.7 UniProtKB/TrEMBL
  ENSRNOT00000051414 ENTREZGENE
  ENSRNOT00000051414.5 UniProtKB/TrEMBL
  ENSRNOT00000110322 ENTREZGENE
  ENSRNOT00000110322.1 UniProtKB/TrEMBL
  ENSRNOT00000115384.1 UniProtKB/TrEMBL
  ENSRNOT00000116737 ENTREZGENE
  ENSRNOT00000116737.1 UniProtKB/TrEMBL
  ENSRNOT00000117717.1 UniProtKB/TrEMBL
  ENSRNOT00000119566 ENTREZGENE
  ENSRNOT00000119566.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NDRG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NDRG4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64457 UniProtKB/TrEMBL
NCBI Gene 64457 ENTREZGENE
PANTHER PTHR11034 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11034:SF21 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ndr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ndrg4 PhenoGen
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZTQ9_RAT UniProtKB/TrEMBL
  A0A8I5ZYL3_RAT UniProtKB/TrEMBL
  A0A8I6A4R1_RAT UniProtKB/TrEMBL
  A0A8I6ARW2_RAT UniProtKB/TrEMBL
  A0A8I6G5X2_RAT UniProtKB/TrEMBL
  D3Z831 ENTREZGENE, UniProtKB/TrEMBL
  D3ZUT8 ENTREZGENE, UniProtKB/TrEMBL
  G3V7P8 ENTREZGENE, UniProtKB/TrEMBL
  NDRG4_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q6XQ62 UniProtKB/Swiss-Prot
  Q6XQ63 UniProtKB/Swiss-Prot
  Q6XQ64 UniProtKB/Swiss-Prot
  Q6XQ65 UniProtKB/Swiss-Prot
  Q78ZK9 UniProtKB/Swiss-Prot
  Q7TST8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-22 Ndrg4  NDRG family member 4  Ndrg4  N-myc downstream regulated gene 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Ndrg4  N-myc downstream regulated gene 4  Ndr4  N-myc downstream regulated 4  Symbol and Name updated 1299863 APPROVED
2004-04-22 Ndr4  N-myc downstream regulated 4  AF045564  development-related protein  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED
2002-08-07 AF045564  development-related protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localizes mainly in the mitochondria and endoplasmic reticulum 1304242
gene_expression expressed widely in the olfactory bulb, cerebral cortex, hippocampus, cerebellum, thalamus, and medulla oblongata 1304220
gene_process plays a role in neurite outgrowth 1304243