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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3567
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rgs4
Name: regulator of G-protein signaling 4
Acc ID: CHEBI:41774
Term: tamoxifen
Definition: A stilbenoid that has formula 371.51460.
Chemical ID: MESH:D013629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rgs4affects expressionISORGS4 (Homo sapiens)6480464CTDTamoxifen affects the expression of RGS4 mRNAPMID:14699072
Rgs4multiple interactionsISORGS4 (Homo sapiens)6480464CTD[Tamoxifen co-treated with ESR1 protein] results in increased expression of RGS4 mRNA; [Tamoxifen co-treated with ESR2 protein] results in increased expression of RGS4 mRNAPMID:19059307
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