Crp (C-reactive protein) - Rat Genome Database

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Gene: Crp (C-reactive protein) Rattus norvegicus
Analyze
Symbol: Crp
Name: C-reactive protein
RGD ID: 2411
Description: Enables cholesterol binding activity; identical protein binding activity; and low-density lipoprotein particle binding activity. Involved in several processes, including cellular response to nitric oxide; complement activation, classical pathway; and negative regulation of superoxide anion generation. Located in extracellular space; filopodium; and growth cone. Used to study rheumatoid arthritis. Biomarker of several diseases, including acute kidney failure; artery disease (multiple); iron deficiency anemia; obesity; and status epilepticus. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); macular degeneration (multiple); middle cerebral artery infarction; and nephritis (multiple). Orthologous to human CRP (C-reactive protein); PARTICIPATES IN classical complement pathway; interleukin-6 signaling pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (R)-lipoic acid; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Aa1249; Ab1-341; Ab2-196; Ac1-114; Ac1262; Ac2-069; Ba2-693; C-reactive protein member of the pentraxin family; C-reactive protein, member of the pentraxin family; C-reactive protein, pentraxin-related; C-reactive protein, petaxin related
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21385,131,635 - 85,175,179 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl1391,054,974 - 91,093,713 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01391,080,448 - 91,081,358 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01395,599,418 - 95,600,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,702,243 - 88,703,153 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11388,891,058 - 88,892,928 (+)NCBI
Celera1384,770,843 - 84,771,753 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
Acute Coronary Syndrome  (ISO)
acute kidney failure  (IEP,ISO)
acute stress disorder  (ISO)
Acute Uveitis  (IEP,ISO)
aggressive periodontitis  (ISO)
Albuminuria  (ISO)
Alcoholic Fatty Liver  (IEP)
alcoholic liver cirrhosis  (ISO)
Alzheimer's disease  (ISO)
ankylosing spondylitis  (ISO)
antiphospholipid syndrome  (ISO)
anxiety disorder  (ISO)
Arsenic Poisoning  (ISO)
aspergillosis  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
atrial fibrillation  (ISO)
Bacteremia  (ISO)
bacterial infectious disease  (ISO)
bacterial meningitis  (ISO)
Behcet's disease  (ISO)
Brain Injuries  (ISO)
breast cancer  (ISO)
breast carcinoma  (ISO)
bronchiolitis  (ISO)
Burns  (IEP)
Cardiac Arrhythmias  (ISO)
cardiovascular system disease  (ISO)
cerebrovascular disease  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chronic Hepatitis C  (ISO)
chronic obstructive pulmonary disease  (ISO)
colon cancer  (IEP)
congestive heart failure  (ISO)
Contrast-Induced Nephropathy  (ISO)
coronary artery disease  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
Diabetic Foot  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
disease by infectious agent  (ISO)
disease of metabolism  (ISO)
end stage renal disease  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (IDA,ISO)
Experimental Liver Cirrhosis  (IEP)
familial hyperlipidemia  (IEP)
Fever of Unknown Origin  (ISO)
gastrointestinal stromal tumor  (ISO)
heart disease  (ISO)
hepatocellular carcinoma  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Human Influenza  (ISO)
hypertension  (IEP,ISO)
hypertensive retinopathy  (ISO)
Hypertriglyceridemia  (ISO)
Hypoxia  (ISO)
Hypoxia-Ischemia, Brain  (ISO)
Inflammation  (IEP,ISO)
inflammatory bowel disease  (ISO)
intermediate coronary syndrome  (ISO)
interstitial cystitis  (ISO)
interstitial nephritis  (ISO)
Intestinal Reperfusion Injury  (IEP)
iron deficiency anemia  (IEP)
juvenile rheumatoid arthritis  (ISO)
Kawasaki disease  (ISO)
kidney failure  (ISO)
Kuhnt-Junius degeneration  (ISO)
Left Ventricular Hypertrophy  (ISO)
leishmaniasis  (ISO)
liver cirrhosis  (ISO)
low tension glaucoma  (ISO)
Lung Neoplasms  (ISO)
lupus nephritis  (ISO)
Lymphatic Metastasis  (ISO)
macular degeneration  (ISO)
malaria  (ISO)
mastoiditis  (ISO)
meningitis  (ISO)
mental depression  (ISO)
Metabolic Syndrome  (ISO)
mevalonic aciduria  (ISO)
middle cerebral artery infarction  (ISO)
mouth disease  (IEP)
Mycoplasma pneumoniae pneumonia  (ISO)
myocardial infarction  (IEP,ISO)
Myocardial Ischemia  (IEP,ISO)
Myocardial Reperfusion Injury  (IEP)
myocarditis  (ISO)
non-arteritic anterior ischemic optic neuropathy  (ISO)
obesity  (IEP,ISO)
obstructive sleep apnea  (ISO)
otitis externa  (ISO)
otitis media  (ISO)
Overactive Urinary Bladder  (ISO)
parathyroid carcinoma  (ISO)
Parkinson's disease  (ISO)
Pasteurellaceae Infections  (ISO)
pelvic inflammatory disease  (ISO)
periodontitis  (ISO)
pharyngoconjunctival fever  (ISO)
Pneumococcal Pneumonia  (ISO)
pneumonia  (ISO)
polymyalgia rheumatica  (ISO)
Polypoidal Choroidal Vasculopathy  (ISO)
Postoperative Atrial Fibrillation  (ISO)
Pseudomonas Infections  (IEP,ISO)
psoriasis  (ISO)
pulmonary hypertension  (ISO)
pulmonary sarcoidosis  (ISO)
pulmonary tuberculosis  (ISO)
pyelonephritis  (IEP)
renal cell carcinoma  (ISO)
Renal Colic  (ISO)
renal fibrosis  (ISO)
renal hypertension  (IEP)
retinal vein occlusion  (ISO)
rheumatoid arthritis  (IDA,ISO)
secondary hyperparathyroidism  (ISO)
Sepsis  (IEP,ISO)
Sjogren's syndrome  (ISO)
Spinal Cord Injuries  (IDA)
status epilepticus  (IEP)
systemic lupus erythematosus  (ISO)
temporal arteritis  (ISO)
thrombosis  (ISO)
Tubulointerstitial Nephritis and Uveitis  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
urticaria  (ISO)
uveal melanoma  (ISO)
vestibular neuronitis  (ISO)
visceral leishmaniasis  (ISO)
withdrawal disorder  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoic acid  (ISO)
(R)-lipoic acid  (EXP)
(R)-mevalonic acid  (ISO)
1,1-dichloroethene  (EXP)
1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine  (ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (ISO)
3',5'-cyclic AMP  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
abacavir  (ISO)
acalabrutinib  (ISO)
acetamide  (EXP)
acetic acid  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
alclofenac  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
amiodarone  (ISO)
amlodipine  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (EXP)
atorvastatin calcium  (EXP,ISO)
benzbromarone  (ISO)
benzene  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzylpenicillin  (ISO)
bezafibrate  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bivalirudin  (ISO)
Bromperidol  (ISO)
cadmium atom  (ISO)
calcitriol  (ISO)
candesartan  (ISO)
carbon monoxide  (ISO)
carbon nanotube  (ISO)
carnosine  (EXP,ISO)
carvedilol  (EXP,ISO)
celecoxib  (ISO)
chromium(6+)  (ISO)
clofibric acid  (EXP)
clozapine  (ISO)
cobalt dichloride  (EXP)
cocaine  (ISO)
colesevelam hydrochloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (EXP,ISO)
curcumin  (EXP,ISO)
cyanocob(III)alamin  (ISO)
cyclosporin A  (EXP,ISO)
cyproconazole  (ISO)
cyproterone acetate  (ISO)
D-penicillamine  (ISO)
daidzein  (ISO)
delta-tocotrienol  (ISO)
deoxynivalenol  (ISO)
desferrioxamine B  (EXP)
desogestrel  (ISO)
diarsenic trioxide  (EXP)
diclofenac  (EXP,ISO)
dienogest  (ISO)
disodium selenite  (ISO)
doxazosin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
eptifibatide  (ISO)
erythromycin A  (ISO)
ethanol  (EXP,ISO)
ezetimibe  (ISO)
fenofibrate  (ISO)
flucloxacillin  (ISO)
flunitrazepam  (ISO)
flutamide  (EXP)
folic acid  (ISO)
fosfomycin  (ISO)
fructose  (EXP,ISO)
fumonisin B1  (ISO)
furan  (EXP)
gamma-tocopherol  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
gestodene  (ISO)
ginsenoside Re  (EXP)
heparin  (ISO)
indinavir  (ISO)
iron(2+) sulfate (anhydrous)  (ISO)
iron(III) citrate  (ISO)
ivermectin  (ISO)
kaempferol  (ISO)
L-arginine  (EXP)
L-ascorbic acid  (ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
levonorgestrel  (ISO)
lipoic acid  (EXP)
lipopolysaccharide  (ISO)
medroxyprogesterone acetate  (ISO)
metformin  (EXP,ISO)
milrinone  (ISO)
mono(2-ethyl-5-hydroxyhexyl) phthalate  (ISO)
mono(2-ethyl-5-oxohexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
morphine  (ISO)
myricitrin  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
neoechinulin A  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nicotinic acid  (ISO)
nitrogen dioxide  (ISO)
nomegestrol  (ISO)
nomegestrol acetate  (ISO)
Nonidet P-40  (ISO)
norgestimate  (ISO)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
oleic acid  (ISO)
olmesartan  (ISO)
Olmesartan medoxomil  (EXP)
p-menthan-3-ol  (EXP)
pamidronate  (ISO)
paracetamol  (ISO)
Pentoxifylline  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
phosphatidylcholine  (ISO)
pioglitazone  (EXP,ISO)
pirinixic acid  (ISO)
pravastatin  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
pterostilbene  (ISO)
quercetin  (ISO)
resveratrol  (EXP,ISO)
riboflavin  (ISO)
rifampicin  (ISO)
rifamycin SV  (ISO)
rosmarinic acid  (EXP)
rosuvastatin calcium  (ISO)
rotenone  (ISO)
salvianolic acid B  (EXP,ISO)
SB 203580  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium nitrite  (EXP)
sterigmatocystin  (ISO)
streptozocin  (ISO)
superoxide  (EXP)
telmisartan  (ISO)
tetrachloromethane  (EXP)
thalidomide  (ISO)
thioacetamide  (EXP)
tibolone  (ISO)
titanium dioxide  (ISO)
triadimefon  (ISO)
Triptolide  (EXP,ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vitamin E  (ISO)
wortmannin  (ISO)
zaragozic acid A  (EXP,ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
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Additional References at PubMed
PMID:12477932   PMID:16642000   PMID:17279354   PMID:17574226   PMID:17660720   PMID:18254451   PMID:18322245   PMID:18621373   PMID:18786923   PMID:19084272   PMID:19246692   PMID:19263040  
PMID:19680263   PMID:19748488   PMID:19850925   PMID:20332628   PMID:21037097   PMID:21323571   PMID:21633874   PMID:21840509   PMID:21856781   PMID:22201020   PMID:22301267   PMID:22306119  
PMID:22807607   PMID:23376485   PMID:23544079   PMID:24141169   PMID:24642533   PMID:24982116   PMID:25016361   PMID:25109280   PMID:25242580   PMID:25536316   PMID:25708190   PMID:26741265  
PMID:27443845   PMID:27492718   PMID:27989594   PMID:28295592   PMID:29202702   PMID:29330688   PMID:29476059   PMID:29768263   PMID:29849871   PMID:30794428   PMID:33382068  


Genomics

Comparative Map Data
Crp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21385,131,635 - 85,175,179 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl1391,054,974 - 91,093,713 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01391,080,448 - 91,081,358 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01395,599,418 - 95,600,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,702,243 - 88,703,153 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11388,891,058 - 88,892,928 (+)NCBI
Celera1384,770,843 - 84,771,753 (+)NCBICelera
Cytogenetic Map13q24NCBI
CRP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1159,712,289 - 159,714,589 (-)EnsemblGRCh38hg38GRCh38
GRCh381159,712,289 - 159,714,589 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371159,682,079 - 159,684,379 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361157,948,703 - 157,951,003 (-)NCBINCBI36hg18NCBI36
Build 341156,495,152 - 156,497,452NCBI
Celera1132,750,525 - 132,752,817 (-)NCBI
Cytogenetic Map1q23.2NCBI
HuRef1131,038,539 - 131,040,831 (-)NCBIHuRef
CHM1_11161,076,594 - 161,078,894 (-)NCBICHM1_1
Crp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391172,525,623 - 172,527,533 (+)NCBIGRCm39mm39
GRCm39 Ensembl1172,525,622 - 172,660,598 (+)Ensembl
GRCm381172,698,056 - 172,699,966 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1172,698,055 - 172,833,031 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,628,187 - 174,630,097 (+)NCBIGRCm37mm9NCBIm37
MGSCv361174,534,741 - 174,536,635 (+)NCBImm8
Celera1175,548,254 - 175,550,142 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map180.13NCBI
CRP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11138,858,353 - 138,860,652 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01135,062,102 - 135,064,402 (-)NCBIMhudiblu_PPA_v0panPan3
CRP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13822,396,787 - 22,398,180 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3822,396,263 - 22,399,166 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3822,473,724 - 22,475,116 (+)NCBI
ROS_Cfam_1.03822,519,785 - 22,521,176 (+)NCBI
UMICH_Zoey_3.13822,286,369 - 22,287,757 (+)NCBI
UNSW_CanFamBas_1.03822,818,770 - 22,820,163 (+)NCBI
UU_Cfam_GSD_1.03823,230,160 - 23,231,548 (+)NCBI
LOC101969640
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050585,866,551 - 5,870,192 (-)NCBI
SpeTri2.0NW_004936740885,855 - 888,854 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl490,722,352 - 90,805,236 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1490,793,361 - 90,801,020 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2498,764,964 - 98,772,727 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103223751
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1204,232,262 - 4,235,826 (+)NCBI
ChlSab1.1 Ensembl204,232,913 - 4,235,377 (+)Ensembl
Vero_WHO_p1.0NW_0236660383,340,251 - 3,342,511 (+)NCBI
Crp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247941,531,555 - 1,533,804 (+)NCBI

Position Markers
Crp  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21385,162,863 - 85,163,015 (+)MAPPERmRatBN7.2
Rnor_6.01391,081,476 - 91,081,627NCBIRnor6.0
Rnor_5.01395,600,446 - 95,600,597UniSTSRnor5.0
RGSC_v3.41388,703,271 - 88,703,422UniSTSRGSC3.4
Celera1384,771,871 - 84,772,022UniSTS
Cytogenetic Map13q24UniSTS
AU048742  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14q11UniSTS
Cytogenetic Map13q27UniSTS
Cytogenetic Map13q24UniSTS
Cytogenetic Map20q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
8655959Pur32Proteinuria QTL 328.4total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat
1302791Stl29Serum triglyceride level QTL 293.30.0011blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)138473078886800898Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:74
Interacting mature miRNAs:83
Transcripts:ENSRNOT00000000058
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 19 13 13
Medium 2 2 30 14 18 14 2 2 11 10 9 10 2
Low 1 15 14 14 1 14 6 9 57 25 32 1 6
Below cutoff 26 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_017096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY310153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY318961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY321318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY321324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY325196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY325218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY325232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC091157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HH755429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI986631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ438897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M83176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000000058   ⟹   ENSRNOP00000000058
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1391,080,341 - 91,081,629 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091089   ⟹   ENSRNOP00000074751
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1391,054,974 - 91,093,713 (+)Ensembl
RefSeq Acc Id: NM_017096   ⟹   NP_058792
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21385,161,836 - 85,162,746 (+)NCBI
Rnor_6.01391,080,448 - 91,081,358 (+)NCBI
Rnor_5.01395,599,418 - 95,600,328 (+)NCBI
RGSC_v3.41388,702,243 - 88,703,153 (+)RGD
Celera1384,770,843 - 84,771,753 (+)RGD
Sequence:
RefSeq Acc Id: XM_039090386   ⟹   XP_038946314
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21385,131,635 - 85,175,179 (+)NCBI
RefSeq Acc Id: XM_039090387   ⟹   XP_038946315
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21385,135,384 - 85,175,178 (+)NCBI
Protein Sequences
Protein RefSeqs NP_058792 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946314 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946315 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40964 (Get FASTA)   NCBI Sequence Viewer  
  AAH91157 (Get FASTA)   NCBI Sequence Viewer  
  AAP78761 (Get FASTA)   NCBI Sequence Viewer  
  AAP85372 (Get FASTA)   NCBI Sequence Viewer  
  AAP86250 (Get FASTA)   NCBI Sequence Viewer  
  AAP86256 (Get FASTA)   NCBI Sequence Viewer  
  AAP92597 (Get FASTA)   NCBI Sequence Viewer  
  AAP92619 (Get FASTA)   NCBI Sequence Viewer  
  AAP92633 (Get FASTA)   NCBI Sequence Viewer  
  AFA37850 (Get FASTA)   NCBI Sequence Viewer  
  AFA37851 (Get FASTA)   NCBI Sequence Viewer  
  AFA37852 (Get FASTA)   NCBI Sequence Viewer  
  AFA37853 (Get FASTA)   NCBI Sequence Viewer  
  AFA37854 (Get FASTA)   NCBI Sequence Viewer  
  AFA37855 (Get FASTA)   NCBI Sequence Viewer  
  AFA37856 (Get FASTA)   NCBI Sequence Viewer  
  AFA37857 (Get FASTA)   NCBI Sequence Viewer  
  AFA37858 (Get FASTA)   NCBI Sequence Viewer  
  AFA37859 (Get FASTA)   NCBI Sequence Viewer  
  AFA37860 (Get FASTA)   NCBI Sequence Viewer  
  AFA37861 (Get FASTA)   NCBI Sequence Viewer  
  AFA37862 (Get FASTA)   NCBI Sequence Viewer  
  AFA37863 (Get FASTA)   NCBI Sequence Viewer  
  AFA37864 (Get FASTA)   NCBI Sequence Viewer  
  AFA37865 (Get FASTA)   NCBI Sequence Viewer  
  AFA37866 (Get FASTA)   NCBI Sequence Viewer  
  AFA37867 (Get FASTA)   NCBI Sequence Viewer  
  AFA37868 (Get FASTA)   NCBI Sequence Viewer  
  AFA37869 (Get FASTA)   NCBI Sequence Viewer  
  CBW53726 (Get FASTA)   NCBI Sequence Viewer  
  CBY88722 (Get FASTA)   NCBI Sequence Viewer  
  EDL94725 (Get FASTA)   NCBI Sequence Viewer  
  P48199 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_058792   ⟸   NM_017096
- Peptide Label: precursor
- UniProtKB: P48199 (UniProtKB/Swiss-Prot),   H6X2W5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000000058   ⟸   ENSRNOT00000000058
RefSeq Acc Id: ENSRNOP00000074751   ⟸   ENSRNOT00000091089
RefSeq Acc Id: XP_038946314   ⟸   XM_039090386
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038946315   ⟸   XM_039090387
- Peptide Label: isoform X1
Protein Domains
Pentraxin (PTX)

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699031
Promoter ID:EPDNEW_R9556
Type:multiple initiation site
Name:Crp_1
Description:C-reactive protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01391,080,367 - 91,080,427EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2411 AgrOrtholog
Ensembl Genes ENSRNOG00000000053 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000000058 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000074751 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000058 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000091089 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7368286 IMAGE-MGC_LOAD
InterPro ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pentaxin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pentraxin-related UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pro-rich UniProtKB/TrEMBL
KEGG Report rno:25419 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:108726 IMAGE-MGC_LOAD
NCBI Gene 25419 ENTREZGENE
PANTHER PTHR23203 UniProtKB/TrEMBL
Pfam Pentaxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pro-rich UniProtKB/TrEMBL
PharmGKB CRP RGD
PhenoGen Crp PhenoGen
PRINTS PENTAXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PTX_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Pro-rich UniProtKB/TrEMBL
  PTX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K8V5_RAT UniProtKB/TrEMBL
  CRP_RAT UniProtKB/Swiss-Prot
  H6X2V2_RAT UniProtKB/TrEMBL
  H6X2V3_RAT UniProtKB/TrEMBL
  H6X2V4_RAT UniProtKB/TrEMBL
  H6X2V7_RAT UniProtKB/TrEMBL
  H6X2V8_RAT UniProtKB/TrEMBL
  H6X2V9_RAT UniProtKB/TrEMBL
  H6X2W0_RAT UniProtKB/TrEMBL
  H6X2W1_RAT UniProtKB/TrEMBL
  H6X2W2_RAT UniProtKB/TrEMBL
  H6X2W3_RAT UniProtKB/TrEMBL
  H6X2W4_RAT UniProtKB/TrEMBL
  H6X2W5 ENTREZGENE, UniProtKB/TrEMBL
  H6X2W6_RAT UniProtKB/TrEMBL
  H6X2W7_RAT UniProtKB/TrEMBL
  H6X2X0_RAT UniProtKB/TrEMBL
  P48199 ENTREZGENE
  Q63133_RAT UniProtKB/TrEMBL
  Q63134_RAT UniProtKB/TrEMBL
UniProt Secondary Q5BK94 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-24 Crp  C-reactive protein  Crp  C-reactive protein, pentraxin-related  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Crp  C-reactive protein, pentraxin-related      Name updated 1299863 APPROVED
2002-06-10 Crp  C-reactive protein      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_protein glycoprotein that exists as a covalently-linked dimer 1298812