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Gene: Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2) Rattus norvegicus
Symbol: Ndufs2
Name: NADH:ubiquinone oxidoreductase core subunit S2
RGD ID: 1307109
Description: Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone and response to oxidative stress. Predicted to localize to mitochondrial respiratory chain complex I and nucleoplasm. Human ortholog(s) of this gene implicated in Leigh disease; hypertrophic cardiomyopathy; inherited metabolic disorder; mitochondrial complex I deficiency; and multiple sclerosis. Orthologous to human NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2); PARTICIPATES IN doxorubicin pharmacokinetics pathway; Alzheimer's disease pathway; Huntington's disease pathway; INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: CI-49kD; complex I-49kD; LOC289218; NADH dehydrogenase (ubiquinone) Fe-S protein 2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; NADH-ubiquinone oxidoreductase 49 kDa subunit
Homo sapiens (human) : NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2)  HGNC  Alliance
Mus musculus (house mouse) : Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2)
Pan paniscus (bonobo/pygmy chimpanzee) : NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2)
Canis lupus familiaris (dog) : NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2)
Sus scrofa (pig) : NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2)
Chlorocebus sabaeus (African green monkey) : NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2)
Heterocephalus glaber (naked mole-rat) : Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01389,606,848 - 89,623,506 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,606,840 - 89,619,398 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,233,713 - 94,250,285 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01395,769,663 - 95,770,563 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,124,431 - 87,137,497 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11387,313,317 - 87,326,381 (-)NCBI
Celera1383,285,589 - 83,298,039 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ndufs2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307109
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.