Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes Projects (beta) QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2) Rattus norvegicus

Analyze

Symbol:

Ndufs2

Name:

NADH:ubiquinone oxidoreductase core subunit S2

RGD ID:

1307109

Description:

Enables oxygen sensor activity. Contributes to NADH dehydrogenase (ubiquinone) activity. Involved in cellular response to oxygen levels and mitochondrial electron transport, NADH to ubiquinone. Located in mitochondrial inner membrane. Part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Leigh disease; hypertrophic cardiomyopathy; inherited metabolic disorder; multiple sclerosis; and nuclear type mitochondrial complex I deficiency 6. Orthologous to human NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2); PARTICIPATES IN doxorubicin pharmacokinetics pathway; Alzheimer's disease pathway; Huntington's disease pathway; INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

CI-49kD; complex I-49kD; LOC103690046; LOC289218; NADH dehydrogenase (ubiquinone) Fe-S protein 2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial-like; NADH-ubiquinone oxidoreductase 49 kDa subunit

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB
Mus musculus (house mouse):	Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	gas-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ND-49	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ND-49L	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	nduf-2.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ndufs2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	83,654,402 - 83,671,474 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	83,654,406 - 83,671,420 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	86,160,251 - 86,172,822 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	87,558,491 - 87,571,027 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	84,790,115 - 84,802,527 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	89,606,848 - 89,623,506 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	89,606,840 - 89,619,398 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	95,769,663 - 95,770,563 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	13	94,233,713 - 94,250,285 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	87,124,431 - 87,137,497 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	87,313,317 - 87,326,381 (-)	NCBI
Celera	13	83,285,589 - 83,298,039 (-)	NCBI		Celera
Cytogenetic Map	13	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autoimmune interstitial lung, joint, and kidney disease (ISO)

cardiomyopathy (ISO)

Experimental Diabetes Mellitus (IEP)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

hypertrophic cardiomyopathy (ISO)

inherited metabolic disorder (ISO)

Leber hereditary optic neuropathy (ISO)

Leigh disease (ISO)

mitochondrial complex I deficiency (ISO)

mitochondrial encephalomyopathy (ISO)

multiple sclerosis (ISO)

nuclear type mitochondrial complex I deficiency 1 (ISO)

nuclear type mitochondrial complex I deficiency 6 (ISO)

parathyroid carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-dexrazoxane (ISO)

1,2-dimethylhydrazine (ISO)

1,3,5-trinitro-1,3,5-triazinane (EXP)

17alpha-ethynylestradiol (ISO)

2,2,2-tetramine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

acetamide (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

CGP 52608 (ISO)

clofibrate (ISO)

cocaine (ISO)

copper(II) sulfate (ISO)

cyclophosphamide (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

fenthion (ISO)

folic acid (ISO)

gentamycin (EXP)

hypochlorous acid (ISO)

isoniazide (ISO)

ivermectin (ISO)

lead(0) (ISO)

lipopolysaccharide (ISO)

menadione (ISO)

mercury atom (ISO)

mercury(0) (ISO)

methidathion (ISO)

niclosamide (ISO)

oxybenzone (EXP)

paracetamol (EXP,ISO)

perfluorooctanoic acid (ISO)

pyrroloquinoline quinone (EXP)

resveratrol (ISO)

rotenone (EXP,ISO)

sodium fluoride (ISO)

streptozocin (EXP)

sunitinib (ISO)

titanium dioxide (ISO)

urethane (ISO)

valproic acid (ISO)

zidovudine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

cellular response to oxygen levels (IMP,ISO)

gliogenesis (ISO,ISS)

mitochondrial ATP synthesis coupled electron transport (ISO)

mitochondrial electron transport, NADH to ubiquinone (IBA,IMP,ISO)

mitochondrial respiratory chain complex I assembly (ISO,ISS)

neural precursor cell proliferation (ISO,ISS)

neurogenesis (ISO,ISS)

response to oxidative stress (ISO)

Cellular Component

mitochondrial inner membrane (IDA,IEA,ISO)

mitochondrial respiratory chain complex I (IBA,IDA,ISO)

mitochondrion (ISO)

nucleoplasm (IEA,ISO)

respirasome (IEA)

Molecular Function

4 iron, 4 sulfur cluster binding (IEA)

metal ion binding (IEA)

NAD binding (IEA)

NADH dehydrogenase (ubiquinone) activity (IMP,ISO)

NADH dehydrogenase activity (ISO)

oxidoreductase activity, acting on NAD(P)H (IEA)

oxygen sensor activity (IMP,ISO)

protein binding (ISO)

quinone binding (IEA)

ubiquitin protein ligase binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Alzheimer's disease pathway (IEA)

doxorubicin pharmacokinetics pathway (ISO)

Huntington's disease pathway (IEA)

oxidative phosphorylation pathway (IEA)

Parkinson's disease pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Diminished superoxide generation is associated with respiratory chain dysfunction and changes in the mitochondrial proteome of sensory neurons from diabetic rats.	Akude E, etal., Diabetes. 2011 Jan;60(1):288-97. Epub 2010 Sep 28.
2.	Investigation of the role of mitochondrial DNA in multiple sclerosis susceptibility.	Ban M, etal., PLoS One. 2008 Aug 6;3(8):e2891.
3.	Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.	Dunham-Snary KJ, etal., Circ Res. 2019 Jun 7;124(12):1727-1746. doi: 10.1161/CIRCRESAHA.118.314284. Epub 2019 Mar 29.
4.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
6.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
7.	Mutations in the complex I NDUFS2 gene of patients with cardiomyopathy and encephalomyopathy.	Loeffen J, etal., Ann Neurol. 2001 Feb;49(2):195-201.
8.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
9.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
10.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
11.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
12.	GOA pipeline	RGD automated data pipeline
13.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
15.	Comprehensive gene review and curation	RGD comprehensive gene curation
16.	The p.M292T NDUFS2 mutation causes complex I-deficient Leigh syndrome in multiple families.	Tuppen HA, etal., Brain. 2010 Oct;133(10):2952-63. Epub 2010 Sep 6.

Additional References at PubMed

PMID:9585441	PMID:11112787	PMID:12477932	PMID:12611891	PMID:12857734	PMID:14651853	PMID:14749350	PMID:17209039	PMID:18614015	PMID:19725078	PMID:21700703	PMID:24746669
PMID:29476059

Genomics

Comparative Map Data

Ndufs2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	83,654,402 - 83,671,474 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	83,654,406 - 83,671,420 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	86,160,251 - 86,172,822 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	87,558,491 - 87,571,027 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	84,790,115 - 84,802,527 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	89,606,848 - 89,623,506 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	89,606,840 - 89,619,398 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	95,769,663 - 95,770,563 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	13	94,233,713 - 94,250,285 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	87,124,431 - 87,137,497 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	87,313,317 - 87,326,381 (-)	NCBI
Celera	13	83,285,589 - 83,298,039 (-)	NCBI		Celera
Cytogenetic Map	13	q24	NCBI

NDUFS2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	161,197,417 - 161,214,395 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	161,197,104 - 161,214,723 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	161,167,207 - 161,184,185 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	159,435,729 - 159,450,809 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	157,982,177 - 157,997,255	NCBI
Celera	1	134,236,257 - 134,251,337 (+)	NCBI		Celera
Cytogenetic Map	1	q23.3	NCBI
HuRef	1	132,526,050 - 132,541,132 (+)	NCBI		HuRef
CHM1_1	1	162,565,343 - 162,580,438 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	160,334,507 - 160,351,847 (+)	NCBI		T2T-CHM13v2.0

Ndufs2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	171,062,422 - 171,078,956 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	171,062,422 - 171,078,957 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	171,234,853 - 171,251,686 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	171,234,853 - 171,251,388 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	173,164,991 - 173,177,243 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	173,071,535 - 173,083,787 (-)	NCBI		MGSCv36	mm8
Celera	1	173,691,078 - 173,703,327 (-)	NCBI		Celera
Cytogenetic Map	1	H3	NCBI
cM Map	1	79.25	NCBI

Ndufs2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	12,961,915 - 12,971,095 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	12,961,873 - 12,971,278 (+)	NCBI	ChiLan1.0	ChiLan1.0

NDUFS2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	1	88,327,913 - 88,341,098 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	136,609,822 - 136,626,851 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	140,526,690 - 140,538,705 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	140,526,690 - 140,538,705 (+)	Ensembl	panpan1.1		panPan2

NDUFS2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	21,271,603 - 21,281,140 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	21,271,675 - 21,285,279 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	21,346,459 - 21,356,011 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	21,389,447 - 21,399,000 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	21,389,447 - 21,398,979 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	21,285,733 - 21,286,858 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	21,691,735 - 21,701,283 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	22,100,884 - 22,110,441 (-)	NCBI		UU_Cfam_GSD_1.0

Ndufs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	7,294,911 - 7,305,582 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936903	499,300 - 514,893 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936903	503,633 - 514,235 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NDUFS2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	89,246,960 - 89,257,085 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	89,246,958 - 89,257,090 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	97,103,640 - 97,113,761 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NDUFS2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	2,767,864 - 2,780,336 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	2,768,064 - 2,780,704 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	1,816,231 - 1,830,038 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ndufs2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	172,707 - 185,073 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624794	172,543 - 189,031 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ndufs2
95 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	118
Count of miRNA genes:	98
Interacting mature miRNAs:	108
Transcripts:	ENSRNOT00000058423
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	101056920	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	8897350	101631289	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	20605871	101339738	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	30395351	101056920	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	31241331	93395974	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	39754544	84754544	Rat
12879444	Bp397	Blood pressure QTL 397			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45049404	90049404	Rat
12879471	Bp398	Blood pressure QTL 398			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45514719	90514719	Rat
12879441	Bp396	Blood pressure QTL 396			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45699983	90699983	Rat
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	46088046	91088046	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	46197976	84753113	Rat
1641901	Alcrsp6	Alcohol response QTL 6			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	13	52362171	97362171	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	56056920	101056920	Rat
738026	Lnnr5	Liver neoplastic nodule remodeling QTL 5	3.29		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	59874408	85581182	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	61825626	106807694	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	65103704	106807694	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	65103704	106807694	Rat
8655945	Rf61	Renal function QTL 61	3.6		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	13	69060519	86800898	Rat
1331783	Bp221	Blood pressure QTL 221	3.72886		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	69060519	86800898	Rat
1300166	Kidm6	Kidney mass QTL 6	3.93		kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	13	69060519	86800898	Rat
8655959	Pur32	Proteinuria QTL 32	8.4		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	74023918	97213863	Rat
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	74862117	85581182	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	74862117	101339893	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	80753256	106807694	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001011907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003751277	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598711	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090505	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC099236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC082067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216640	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ224373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000058423 ⟹ ENSRNOP00000055224

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	83,654,406 - 83,671,420 (-)	Ensembl
Rnor_6.0 Ensembl	13	89,606,840 - 89,619,398 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000094027 ⟹ ENSRNOP00000090418

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	83,654,406 - 83,671,420 (-)	Ensembl

RefSeq Acc Id:

NM_001011907 ⟹ NP_001011907

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	83,654,407 - 83,666,945 (-)	NCBI
Rnor_6.0	13	89,606,853 - 89,619,388 (-)	NCBI
Rnor_5.0	13	95,769,663 - 95,770,563 (-)	NCBI
RGSC_v3.4	13	87,124,431 - 87,137,497 (-)	RGD
Celera	13	83,285,589 - 83,298,039 (-)	RGD

Sequence:

show sequence

GTAAAGATGGCGGCCCTCAGGGCTGTGTGCAGCCTCCGCGGTGTCGGGGCCCAGGTGCTGCGGG
CCGGGTCTGGGATTCGTCTGCCGAGTCAGCCCAGCAGAGGTGCTCGGCGATGGCAGCCAGATAT
AGAATGGGCAGAGCAGTTTTCGGGAGCTGTCATGTATCCCTCCAAGGAAACAGCCCACTGGAAA
CCTCCTCCTTGGAATGATGTGGATGTTTTGAAGGAGAAAGTGGTGACCAACGTGACCCTGAACT
TTGGGCCCCAGCACCCAGCAGCTCATGGAGTCCTGAGACTCGTGCTGGAATTGAGTGGAGAGAT
GGTGCGGAAATGTGACCCTCACATCGGGCTCCTACACCGAGGCACGGAGAAGCTCATCGAGTAC
AAGACCTATCTGCAGGCCCTTCCATATTTTGACCGGTTGGACTATGTGTCCATGATGTGTAATG
AACAGGCGTATTCACTAGCTGTGGAGAAGTTGCTAAACATCCAGCCTCCTCCCCGGGCGCAGTG
GATCCGAGTGCTCTTTGGAGAGATCACACGGATTTTAAACCATATCATGGCTGTCACCACACAT
GCCCTGGACATTGGTGCCATGACGCCTTTCTTCTGGATGTTTGAAGAAAGGGAGAAGATGTTCG
AGTTCTATGAGCGGGTGTCTGGAGCCCGTATGCATGCTGCTTATATCCGACCAGGAGGAGTGCA
CCAGGACCTACCTCTTGGGCTTATGGATGACATTTATGAATTTTCCAAGAACTTCTCTCTTCGG
ATTGATGAGGTGGAGGAGATGCTGACCAACAATAGAATCTGGCGAAATAGGACAGTCGACATTG
GGGTTGTATCTGCAGAAGATGCACTGAACTATGGATTCAGTGGAGTGATGCTCCGAGGCTCAGG
CATCCAGTGGGACTTGCGGAAGACCCAGCCATATGATGTTTACGACCAGGTGGAGTTTGATGTT
CCTATTGGTTCTCGAGGGGACTGCTACGATAGGTATCTGTGTCGTGTGGAAGAGATGCGCCAGT
CCCTTCGAATCATCGAACAGTGTCTGAACAAGATGCCGCCGGGGGAGATCAAGGTTGATGACGC
CAAAGTGTCCCCACCTAAACGAGCAGAGATGAAGACGTCCATGGAGTCACTAATTCATCACTTT
AAGCTGTATACTGAGGGCTACCAAGTTCCTCCAGGAGCCACATACACCGCCATTGAAGCTCCTA
AGGGCGAGTTTGGGGTGTACTTGGTATCTGATGGCAGCAGCCGACCTTATCGGTGTAAGATCAA
GGCTCCCGGTTTTGCCCACCTGGCAGGTTTGGACAAGATGTCTAAAGGACACATGCTGGCAGAT
GTCGTAGCCATCATAGGCACCCAGGATATTGTATTTGGAGAAATAGACCGATGAGCAAAAGCAC
AGCCTGTGAGCTCCCTTGCCTGTCAGCTGCTTCATCGAGCGAGGCCTTTGTGTGGTGGGAAACG
AGGCTGTGTTTCAGCAAACATACATGTACTCGTTGACTTAGCTGCACAGGCTTTCTGTGCATGT
ACTAGAAAAGGAGAAATTATATTAAATTAGCCACCTTTGGCCCCTAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_003751277 ⟹ XP_003751325

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	83,654,402 - 83,671,474 (-)	NCBI
Rnor_6.0	13	89,606,848 - 89,623,506 (-)	NCBI
Rnor_5.0	13	94,233,713 - 94,250,285 (-)	NCBI

Sequence:

show sequence

CCCGGTACTGCAATACCCCCAATAGGGCTCCCCTGTCCCAGTGCAGAGACGCCACCGACTCCGG
ATCTCCATTGATGGTGCCAGTCAGGTCTGCAGCCCAGTAAAGATGGCGGCCCTCAGGGCTGTGT
GCAGCCTCCGCGGTGTCGGGGCCCAGGTGCTGCGGGCCGGGTCTGGGATTCGTCTGCCGAGTCA
GCCCAGCAGAGGTGCTCGGCGATGGCAGCCAGATATAGAATGGGCAGAGCAGTTTTCGGGAGCT
GTCATGTATCCCTCCAAGGAAACAGCCCACTGGAAACCTCCTCCTTGGAATGATGTGGATGTTT
TGAAGGAGAAAGTGGTGACCAACGTGACCCTGAACTTTGGGCCCCAGCACCCAGCAGCTCATGG
AGTCCTGAGACTCGTGCTGGAATTGAGTGGAGAGATGGTGCGGAAATGTGACCCTCACATCGGG
CTCCTACACCGAGGCACGGAGAAGCTCATCGAGTACAAGACCTATCTGCAGGCCCTTCCATATT
TTGACCGGTTGGACTATGTGTCCATGATGTGTAATGAACAGGCGTATTCACTAGCTGTGGAGAA
GTTGCTAAACATCCAGCCTCCTCCCCGGGCGCAGTGGATCCGAGTGCTCTTTGGAGAGATCACA
CGGATTTTAAACCATATCATGGCTGTCACCACACATGCCCTGGACATTGGTGCCATGACGCCTT
TCTTCTGGATGTTTGAAGAAAGGGAGAAGATGTTCGAGTTCTATGAGCGGGTGTCTGGAGCCCG
TATGCATGCTGCTTATATCCGACCAGGAGGAGTGCACCAGGACCTACCTCTTGGGCTTATGGAT
GACATTTATGAATTTTCCAAGAACTTCTCTCTTCGGATTGATGAGGTGGAGGAGATGCTGACCA
ACAATAGAATCTGGCGAAATAGGACAGTCGACATTGGGGTTGTATCTGCAGAAGATGCACTGAA
CTATGGATTCAGTGGAGTGATGCTCCGAGGCTCAGGCATCCAGTGGGACTTGCGGAAGACCCAG
CCATATGATGTTTACGACCAGGTGGAGTTTGATGTTCCTATTGGTTCTCGAGGGGACTGCTACG
ATAGGTATCTGTGTCGTGTGGAAGAGATGCGCCAGTCCCTTCGAATCATCGAACAGTGTCTGAA
CAAGATGCCGCCGGGGGAGATCAAGGTTGATGACGCCAAAGTGTCCCCACCTAAACGAGCAGAG
ATGAAGACGTCCATGGAGTCACTAATTCATCACTTTAAGCTGTATACTGAGGGCTACCAAGTTC
CTCCAGGAGCCACATACACCGCCATTGAAGCTCCTAAGGGCGAGTTTGGGGTGTACTTGGTATC
TGATGGCAGCAGCCGACCTTATCGGTGTAAGATCAAGGCTCCCGGTTTTGCCCACCTGGCAGGT
TTGGACAAGATGTCTAAAGGACACATGCTGGCAGATGTCGTAGCCATCATAGGCACCCAGGATA
TTGTATTTGGAGAAATAGACCGATGAGCAAAAGCACAGCCTGTGAGCTCCCTTGCCTGTCAGCT
GCTTCATCGAGCGAGGCCTTTGTGTGGTGGGAAACGAGGCTGTGTTTCAGCAAACATACATGTA
CTCGTTGACTTAGCTGCACAGGCTTTCTGTGCATGTACTAGAAAAGGAGAAATTATATTAAATT
AGCCACCTTTGGCCCCTAAACTCAA

hide sequence

RefSeq Acc Id:

XM_017598711 ⟹ XP_017454200

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	83,654,402 - 83,666,963 (-)	NCBI
Rnor_6.0	13	89,606,848 - 89,619,376 (-)	NCBI

Sequence:

show sequence

GCCCTCAGGGCTGTGTGCAGCCTCCGCGGTGTCGGGGCCCAGGTGCTGCGGGCCGGGTCTGGGA
TTCGTCTGCCGAGTCAGCCCAGCAGGATCTATCTTTAATTCCTCAGAGGTGCTCGGCGATGGCA
GCCAGATATAGAATGGGCAGAGCAGTTTTCGGGAGCTGTCATGTATCCCTCCAAGGAAACAGCC
CACTGGAAACCTCCTCCTTGGAATGATGTGGATGTTTTGAAGGAGAAAGTGGTGACCAACGTGA
CCCTGAACTTTGGGCCCCAGCACCCAGCAGCTCATGGAGTCCTGAGACTCGTGCTGGAATTGAG
TGGAGAGATGGTGCGGAAATGTGACCCTCACATCGGGCTCCTACACCGAGGCACGGAGAAGCTC
ATCGAGTACAAGACCTATCTGCAGGCCCTTCCATATTTTGACCGGTTGGACTATGTGTCCATGA
TGTGTAATGAACAGGCGTATTCACTAGCTGTGGAGAAGTTGCTAAACATCCAGCCTCCTCCCCG
GGCGCAGTGGATCCGAGTGCTCTTTGGAGAGATCACACGGATTTTAAACCATATCATGGCTGTC
ACCACACATGCCCTGGACATTGGTGCCATGACGCCTTTCTTCTGGATGTTTGAAGAAAGGGAGA
AGATGTTCGAGTTCTATGAGCGGGTGTCTGGAGCCCGTATGCATGCTGCTTATATCCGACCAGG
AGGAGTGCACCAGGACCTACCTCTTGGGCTTATGGATGACATTTATGAATTTTCCAAGAACTTC
TCTCTTCGGATTGATGAGGTGGAGGAGATGCTGACCAACAATAGAATCTGGCGAAATAGGACAG
TCGACATTGGGGTTGTATCTGCAGAAGATGCACTGAACTATGGATTCAGTGGAGTGATGCTCCG
AGGCTCAGGCATCCAGTGGGACTTGCGGAAGACCCAGCCATATGATGTTTACGACCAGGTGGAG
TTTGATGTTCCTATTGGTTCTCGAGGGGACTGCTACGATAGGTATCTGTGTCGTGTGGAAGAGA
TGCGCCAGTCCCTTCGAATCATCGAACAGTGTCTGAACAAGATGCCGCCGGGGGAGATCAAGGT
TGATGACGCCAAAGTGTCCCCACCTAAACGAGCAGAGATGAAGACGTCCATGGAGTCACTAATT
CATCACTTTAAGCTGTATACTGAGGGCTACCAAGTTCCTCCAGGAGCCACATACACCGCCATTG
AAGCTCCTAAGGGCGAGTTTGGGGTGTACTTGGTATCTGATGGCAGCAGCCGACCTTATCGGTG
TAAGATCAAGGCTCCCGGTTTTGCCCACCTGGCAGGTTTGGACAAGATGTCTAAAGGACACATG
CTGGCAGATGTCGTAGCCATCATAGGCACCCAGGATATTGTATTTGGAGAAATAGACCGATGAG
CAAAAGCACAGCCTGTGAGCTCCCTTGCCTGTCAGCTGCTTCATCGAGCGAGGCCTTTGTGTGG
TGGGAAACGAGGCTGTGTTTCAGCAAACATACATGTACTCGTTGACTTAGCTGCACAGGCTTTC
TGTGCATGTACTAGAAAAGGAGAAATTATATTAAATTAGCCACCTTTGGCCCCTAAACTCAA

hide sequence

RefSeq Acc Id:

XM_039090505 ⟹ XP_038946433

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	83,654,402 - 83,671,415 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001011907	(Get FASTA)	NCBI Sequence Viewer
	XP_003751325	(Get FASTA)	NCBI Sequence Viewer
	XP_017454200	(Get FASTA)	NCBI Sequence Viewer
	XP_038946433	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH82067	(Get FASTA)	NCBI Sequence Viewer
	Q641Y2	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001011907 ⟸ NM_001011907
- Peptide Label:	precursor
- UniProtKB:	Q641Y2 (UniProtKB/Swiss-Prot), A0A8I6ABR8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAALRAVCSLRGVGAQVLRAGSGIRLPSQPSRGARRWQPDIEWAEQFSGAVMYPSKETAHWKPP PWNDVDVLKEKVVTNVTLNFGPQHPAAHGVLRLVLELSGEMVRKCDPHIGLLHRGTEKLIEYKT YLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRILNHIMAVTTHAL DIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGLMDDIYEFSKNFSLRID EVEEMLTNNRIWRNRTVDIGVVSAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPI GSRGDCYDRYLCRVEEMRQSLRIIEQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKL YTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVV AIIGTQDIVFGEIDR hide sequence

RefSeq Acc Id:	XP_003751325 ⟸ XM_003751277
- Peptide Label:	isoform X1
- UniProtKB:	Q641Y2 (UniProtKB/Swiss-Prot), A0A8I6ABR8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAALRAVCSLRGVGAQVLRAGSGIRLPSQPSRGARRWQPDIEWAEQFSGAVMYPSKETAHWKPP PWNDVDVLKEKVVTNVTLNFGPQHPAAHGVLRLVLELSGEMVRKCDPHIGLLHRGTEKLIEYKT YLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRILNHIMAVTTHAL DIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGLMDDIYEFSKNFSLRID EVEEMLTNNRIWRNRTVDIGVVSAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPI GSRGDCYDRYLCRVEEMRQSLRIIEQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKL YTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVV AIIGTQDIVFGEIDR hide sequence

RefSeq Acc Id:	XP_017454200 ⟸ XM_017598711
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6ABR8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYPSKETAHWKPPPWNDVDVLKEKVVTNVTLNFGPQHPAAHGVLRLVLELSGEMVRKCDPHIGL LHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITR ILNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGLMDD IYEFSKNFSLRIDEVEEMLTNNRIWRNRTVDIGVVSAEDALNYGFSGVMLRGSGIQWDLRKTQP YDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSLRIIEQCLNKMPPGEIKVDDAKVSPPKRAEM KTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGL DKMSKGHMLADVVAIIGTQDIVFGEIDR hide sequence

RefSeq Acc Id:

ENSRNOP00000055224 ⟸ ENSRNOT00000058423

RefSeq Acc Id:	XP_038946433 ⟸ XM_039090505
- Peptide Label:	isoform X1
- UniProtKB:	Q641Y2 (UniProtKB/Swiss-Prot), A0A8I6ABR8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000090418 ⟸ ENSRNOT00000094027

Protein Domains

NADH-quinone oxidoreductase subunit D

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q641Y2-F1-model_v2	AlphaFold	Q641Y2	1-463	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307109	AgrOrtholog
BioCyc Gene	G2FUF-17381	BioCyc
BioCyc Pathway	PWY-3781 [aerobic respiration I (cytochrome c)]	BioCyc
Ensembl Genes	ENSRNOG00000038372	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000055224	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000090418.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000058423	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000094027.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.645.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7132777	IMAGE-MGC_LOAD
InterPro	NADH_Q_OxRdtase_suD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NADH_UbQ_OxRdtase_49kDa_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NDH1_su_D/H	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NiFe-Hase_large	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:289218	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:95229	IMAGE-MGC_LOAD
NCBI Gene	289218	ENTREZGENE
PANTHER	NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR11993	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Complex1_49kDa	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ndufs2	PhenoGen
PROSITE	COMPLEX1_49K	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF56762	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6ABR8	ENTREZGENE, UniProtKB/TrEMBL
	NDUS2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Ndufs2	NADH:ubiquinone oxidoreductase core subunit S2	LOC103690046	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial-like	Data Merged	737654	PROVISIONAL
2017-03-29	Ndufs2	NADH:ubiquinone oxidoreductase core subunit S2	Ndufs2	NADH dehydrogenase (ubiquinone) Fe-S protein 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-08-25	LOC103690046	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-12-06	Ndufs2	NADH dehydrogenase (ubiquinone) Fe-S protein 2	Ndufs2_predicted	NADH dehydrogenase (ubiquinone) Fe-S protein 2 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Ndufs2_predicted	NADH dehydrogenase (ubiquinone) Fe-S protein 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)