Gene: Hnrnpu (heterogeneous nuclear ribonucleoprotein U) Rattus norvegicus
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Symbol: Hnrnpu
Name: heterogeneous nuclear ribonucleoprotein U
Description: ENCODES a protein that exhibits poly(G) binding; promoter-specific chromatin binding; ribonucleoprotein complex binding; INVOLVED IN cellular response to dexamethasone stimulus; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity; positive regulation of gene expression; PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH colorectal cancer (ortholog); early infantile epileptic encephalopathy 54 (ortholog); epilepsy (ortholog); FOUND IN nucleus; ribonucleoprotein complex; catalytic step 2 spliceosome (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,6-dinitrotoluene
AGR Description: Exhibits poly(G) binding activity, promoter-specific chromatin binding activity, and ribonucleoprotein complex binding activity; involved in cellular response to dexamethasone stimulus, positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity, and positive regulation of gene expression; localizes to the nucleus and ribonucleoprotein complex; predicted to colocalize with the RNA polymerase II transcription factor complex; orthologous to human HNRNPU (heterogeneous nuclear ribonucleoprotein U).
Merged Description: Exhibits poly(G) binding activity, promoter-specific chromatin binding activity, and ribonucleoprotein complex binding activity; involved in cellular response to dexamethasone stimulus, positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity, and positive regulation of gene expression; localizes to the nucleus and ribonucleoprotein complex; predicted to colocalize with the RNA polymerase II transcription factor complex; orthologous to human HNRNPU (heterogeneous nuclear ribonucleoprotein U); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hnRNP U; Hnrpu; SAF-A; scaffold-attachment factor A; SN1; SP120; system N1 Na+ and H+-coupled glutamine transporter; transporter protein
Orthologs:
Homo sapiens (human) : HNRNPU (heterogeneous nuclear ribonucleoprotein U)  HGNC  Alliance
Mus musculus (house mouse) : Hnrnpu (heterogeneous nuclear ribonucleoprotein U)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hnrnpu (heterogeneous nuclear ribonucleoprotein U)
Pan paniscus (bonobo/pygmy chimpanzee) : HNRNPU (heterogeneous nuclear ribonucleoprotein U)
Canis lupus familiaris (dog) : HNRNPU (heterogeneous nuclear ribonucleoprotein U)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hnrnpu (heterogeneous nuclear ribonucleoprotein U)
Sus scrofa (pig) : HNRNPU (heterogeneous nuclear ribonucleoprotein U)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01396,222,093 - 96,238,845 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013100,663,218 - 100,679,960 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41393,978,865 - 93,987,654 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11394,168,061 - 94,176,568 (-)NCBI
Celera1389,636,544 - 89,645,333 (-)NCBICelera
Cytogenetic Map13q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

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Gene Ontology Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Hnrnpu
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620372
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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