Fmn2 (formin 2) - Rat Genome Database

Name: Fmn2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Fmn2 (formin 2) Rattus norvegicus

Analyze

Symbol:

Fmn2 (Ensembl: AABR07021812.1)

Name:

formin 2

RGD ID:

2322099

Description:

Predicted to enable actin binding activity. Predicted to be involved in several processes, including cytoskeleton organization; meiotic nuclear division; and positive regulation of double-strand break repair. Predicted to act upstream of or within actin filament bundle assembly and meiotic chromosome movement towards spindle pole. Predicted to be located in several cellular components, including microvillus; nucleolus; and spindle. Predicted to colocalize with actin cytoskeleton. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 47. Orthologous to human FMN2 (formin 2); INTERACTS WITH bisphenol A; 17alpha-ethynylestradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

AABR07021812.1; formin 2-like; formin-2; LOC100360457

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FMN2 (formin 2)	HGNC	HomoloGene, NCBI
Mus musculus (house mouse):	Fmn2 (formin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Fmn2 (formin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FMN2 (formin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FMN2 (formin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Fmn2 (formin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FMN2 (formin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FMN2 (formin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Fmn2 (formin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Fmn2 (formin 2)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	FMN2 (formin 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fmn2b (formin 2b)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder)
Danio rerio (zebrafish):	fmn2a (formin 2a)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	86,454,256 - 86,771,437 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	86,453,926 - 86,771,411 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	13	92,569,256 - 92,887,302 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	92,569,785 - 92,672,821 (+)	NCBI	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	97,035,682 - 97,352,320 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	90,205,332 - 90,520,323 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	13	86,056,421 - 86,372,278 (+)	NCBI		Celera
Cytogenetic Map	13	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive intellectual developmental disorder 47 (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

Hereditary Leiomyomatosis and Renal Cell Cancer (ISO)

Hirschsprung's disease (ISO)

intellectual disability (ISO)

Neurodevelopmental Disorders (ISO)

parathyroid carcinoma (ISO)

renal cell carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

5-aza-2'-deoxycytidine (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium sulfate (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

choline (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

daidzein (ISO)

diarsenic trioxide (ISO)

dichloroacetic acid (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

ethanol (ISO)

folic acid (ISO)

fulvestrant (ISO)

genistein (ISO)

glycitein (ISO)

L-methionine (ISO)

lithium chloride (ISO)

melphalan (ISO)

methapyrilene (ISO)

N-ethyl-N-nitrosourea (ISO)

phenobarbital (ISO)

potassium chromate (ISO)

rotenone (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

toxaphene (ISO)

trichostatin A (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton organization (ISO)

actin filament bundle assembly (ISO)

actin nucleation (IEA)

cell migration (ISO)

cellular response to hypoxia (ISO)

DNA damage response (ISO)

establishment of meiotic spindle localization (ISO)

formin-nucleated actin cable assembly (ISO)

homologous chromosome movement towards spindle pole in meiosis I anaphase (ISO)

intracellular transport (IBA,ISO)

meiotic chromosome movement towards spindle pole (ISO)

negative regulation of apoptotic process (ISO)

negative regulation of protein catabolic process (ISO)

oogenesis (ISO)

polar body extrusion after meiotic divisions (ISO)

positive regulation of double-strand break repair (ISO)

vesicle-mediated transport (ISO)

Cellular Component

actin cytoskeleton (ISO)

actin filament (IEA)

cell cortex (ISO)

cytoplasm (IBA)

cytoplasmic vesicle membrane (ISO)

cytosol (ISO)

endoplasmic reticulum (ISO)

endoplasmic reticulum membrane (IBA,ISO)

microvillus (ISO)

nucleolus (ISO)

nucleus (IBA,ISO)

nucleus (ISO)

spindle (ISO)

Molecular Function

actin binding (ISO)

microtubule binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12447394	PMID:20082305	PMID:21620703	PMID:21983562	PMID:23375502	PMID:23439682	PMID:26287480

Genomics

Comparative Map Data

Fmn2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	86,454,256 - 86,771,437 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	86,453,926 - 86,771,411 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	13	92,569,256 - 92,887,302 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	92,569,785 - 92,672,821 (+)	NCBI	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	97,035,682 - 97,352,320 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	90,205,332 - 90,520,323 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	13	86,056,421 - 86,372,278 (+)	NCBI		Celera
Cytogenetic Map	13	q24	NCBI

FMN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	240,091,883 - 240,475,187 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	1	240,014,348 - 240,475,187 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	240,255,183 - 240,638,487 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	238,321,604 - 238,705,112 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	213,510,402 - 213,893,529 (+)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI
HuRef	1	210,713,436 - 211,096,763 (+)	NCBI		HuRef
CHM1_1	1	241,528,744 - 241,910,469 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	239,505,207 - 239,886,446 (+)	NCBI		T2T-CHM13v2.0

Fmn2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	174,324,079 - 174,650,295 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	174,329,391 - 174,650,295 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	174,501,752 - 174,822,729 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	174,501,825 - 174,822,729 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	176,431,956 - 176,752,860 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	176,325,847 - 176,658,752 (+)	NCBI		MGSCv36	mm8
Celera	1	181,581,367 - 181,911,120 (+)	NCBI		Celera
Cytogenetic Map	1	H3	NCBI
cM Map	1	81.04	NCBI

Fmn2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955406	11,358,585 - 11,666,102 (-)	NCBI	ChiLan1.0	ChiLan1.0

FMN2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	220,621,414 - 221,008,892 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	1	215,626,889 - 216,023,590 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

FMN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	31,657,371 - 32,024,777 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	31,697,245 - 32,023,472 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	31,194,870 - 31,564,912 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	31,478,304 - 31,849,271 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	7	31,315,799 - 31,687,109 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	31,348,230 - 31,718,511 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	31,586,597 - 31,957,372 (+)	NCBI		UU_Cfam_GSD_1.0

Fmn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	44,577,814 - 44,914,520 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936526	9,833,128 - 10,169,267 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936526	9,832,790 - 10,169,488 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FMN2
(Sus scrofa - pig)

No map positions available.

FMN2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	77,187,572 - 77,585,773 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666055	79,293,686 - 79,693,875 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fmn2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624771	10,642,515 - 10,953,480 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624771	10,641,845 - 10,956,213 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Fmn2
1951 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	64
Count of miRNA genes:	57
Interacting mature miRNAs:	61
Transcripts:	ENSRNOT00000072243
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	101056920	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	8897350	101631289	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	20605871	101339738	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	30395351	101056920	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	31241331	93395974	Rat
12879444	Bp397	Blood pressure QTL 397			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45049404	90049404	Rat
12879471	Bp398	Blood pressure QTL 398			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45514719	90514719	Rat
12879441	Bp396	Blood pressure QTL 396			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45699983	90699983	Rat
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	46088046	91088046	Rat
1641901	Alcrsp6	Alcohol response QTL 6			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	13	52362171	97362171	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	56056920	101056920	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	61825626	106807694	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	65103704	106807694	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	65103704	106807694	Rat
8655945	Rf61	Renal function QTL 61	3.6		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	13	69060519	86800898	Rat
1331783	Bp221	Blood pressure QTL 221	3.72886		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	69060519	86800898	Rat
1300166	Kidm6	Kidney mass QTL 6	3.93		kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	13	69060519	86800898	Rat
8655959	Pur32	Proteinuria QTL 32	8.4		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	74023918	97213863	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	74862117	101339893	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	80753256	106807694	Rat
1302791	Stl29	Serum triglyceride level QTL 29	3.3	0.0011	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	13	84730788	86800898	Rat

Markers in Region

D13Got77

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	13	92,845,528 - 92,845,714	NCBI	Rnor6.0
Rnor_5.0	13	97,310,645 - 97,310,831	UniSTS	Rnor5.0
RGSC_v3.4	13	90,480,373 - 90,480,560	RGD	RGSC3.4
RGSC_v3.4	13	90,480,374 - 90,480,560	UniSTS	RGSC3.4
RGSC_v3.1	13	90,669,258 - 90,669,444	RGD
Celera	13	86,331,162 - 86,331,348	UniSTS
RH 3.4 Map	13	575.6	UniSTS
RH 3.4 Map	13	575.6	RGD
RH 2.0 Map	13	637.2	RGD
Cytogenetic Map	13	q24	UniSTS

BF397101

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	86,640,710 - 86,640,950 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	92,755,443 - 92,755,682	NCBI	Rnor6.0
Rnor_5.0	13	97,220,199 - 97,220,438	UniSTS	Rnor5.0
RGSC_v3.4	13	90,391,391 - 90,391,630	UniSTS	RGSC3.4
Celera	13	86,242,128 - 86,242,367	UniSTS
RH 3.4 Map	13	585.7	UniSTS
Cytogenetic Map	13	q24	UniSTS

BF388231

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	86,570,078 - 86,570,242 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	92,684,941 - 92,685,104	NCBI	Rnor6.0
Rnor_5.0	13	97,150,008 - 97,150,171	UniSTS	Rnor5.0
RGSC_v3.4	13	90,319,780 - 90,319,943	UniSTS	RGSC3.4
Celera	13	86,172,457 - 86,172,620	UniSTS
RH 3.4 Map	13	575.9	UniSTS
Cytogenetic Map	13	q24	UniSTS

BF405930

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	86,620,170 - 86,620,393 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	92,734,902 - 92,735,124	NCBI	Rnor6.0
Rnor_5.0	13	97,199,658 - 97,199,880	UniSTS	Rnor5.0
RGSC_v3.4	13	90,370,854 - 90,371,076	UniSTS	RGSC3.4
Celera	13	86,221,577 - 86,221,799	UniSTS
RH 3.4 Map	13	574.5	UniSTS
Cytogenetic Map	13	q24	UniSTS

stSG628095

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Celera	13	86,265,119 - 86,266,359	UniSTS
Cytogenetic Map	13	q24	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_017599005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604690	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091433	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACYVU010000245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000082700 ⟹ ENSRNOP00000070887

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	86,453,926 - 86,558,299 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000102800 ⟹ ENSRNOP00000095777

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	86,453,926 - 86,771,411 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000105445 ⟹ ENSRNOP00000080507

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	86,453,926 - 86,771,411 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000118504 ⟹ ENSRNOP00000097445

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	86,453,926 - 86,771,411 (+)	Ensembl

RefSeq Acc Id:

XM_039091433 ⟹ XP_038947361

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	86,454,256 - 86,771,437 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_038947361	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	XP_038947361 ⟸ XM_039091433
- UniProtKB:	A0A8I6GLS8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000070887 ⟸ ENSRNOT00000082700

RefSeq Acc Id:

ENSRNOP00000095777 ⟸ ENSRNOT00000102800

RefSeq Acc Id:

ENSRNOP00000097445 ⟸ ENSRNOT00000118504

RefSeq Acc Id:

ENSRNOP00000080507 ⟸ ENSRNOT00000105445

Protein Domains

FH2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2JZ27-F1-model_v2	AlphaFold	A0A0G2JZ27	1-1201	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2322099	AgrOrtholog
BioCyc Gene	G2FUF-17248	BioCyc
Ensembl Genes	ENSRNOG00000061764	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000070887.2	UniProtKB/TrEMBL
	ENSRNOP00000080507.1	UniProtKB/TrEMBL
	ENSRNOP00000095777	ENTREZGENE
	ENSRNOP00000095777.1	UniProtKB/TrEMBL
	ENSRNOP00000097445.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000082700.2	UniProtKB/TrEMBL
	ENSRNOT00000102800	ENTREZGENE
	ENSRNOT00000102800.1	UniProtKB/TrEMBL
	ENSRNOT00000105445.1	UniProtKB/TrEMBL
	ENSRNOT00000118504.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.58.2220	UniProtKB/TrEMBL
InterPro	FH2_Formin	UniProtKB/TrEMBL
	FH2_Formin_sf	UniProtKB/TrEMBL
	Formin_Cappuccino_subfam	UniProtKB/TrEMBL
NCBI Gene	100360457	ENTREZGENE
PANTHER	FORMIN	UniProtKB/TrEMBL
	FORMIN-2	UniProtKB/TrEMBL
Pfam	FH2	UniProtKB/TrEMBL
PhenoGen	Fmn2	PhenoGen
PRINTS	FORMIN	UniProtKB/TrEMBL
PROSITE	FH2	UniProtKB/TrEMBL
SMART	FH2	UniProtKB/TrEMBL
Superfamily-SCOP	Formin homology 2 domain (FH2 domain)	UniProtKB/TrEMBL
UniProt	A0A0G2JZ27_RAT	UniProtKB/TrEMBL
	A0A8I5ZQT5_RAT	UniProtKB/TrEMBL
	A0A8I6AUE2_RAT	UniProtKB/TrEMBL
	A0A8I6GLS8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-02	Fmn2	formin 2	AABR07021812.1		Data Merged	737654	PROVISIONAL
2019-11-08	AABR07021812.1				Symbol and Name status set to provisional	45752	PROVISIONAL
2013-08-02	Fmn2	formin 2	LOC100360457	formin 2-like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-06	LOC100360457	formin 2-like			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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