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Gene: Spta1 (spectrin, alpha, erythrocytic 1) Rattus norvegicus
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Symbol: Spta1
Name: spectrin, alpha, erythrocytic 1
Description: Predicted to have protein heterodimerization activity. Predicted to be involved in several processes, including lymphocyte homeostasis; porphyrin-containing compound biosynthetic process; and positive regulation of T cell proliferation. Localizes to the axon and cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in hereditary spherocytosis and hereditary spherocytosis type 3. Orthologous to human SPTA1 (spectrin alpha, erythrocytic 1); INTERACTS WITH 6-propyl-2-thiouracil; aflatoxin B1; Brodifacoum.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: erythroid spectrin alpha; LOC289257; spectrin alpha 1; spectrin alpha chain, erythrocyte; spectrin alpha chain, erythrocytic 1; spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spna1
Orthologs:
Homo sapiens (human) : SPTA1 (spectrin alpha, erythrocytic 1)  HGNC  Alliance
Mus musculus (house mouse) : Spta1 (spectrin alpha, erythrocytic 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spta1 (spectrin alpha, erythrocytic 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SPTA1 (spectrin alpha, erythrocytic 1)
Canis lupus familiaris (dog) : SPTA1 (spectrin alpha, erythrocytic 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spta1 (spectrin alpha, erythrocytic 1)
Sus scrofa (pig) : SPTA1 (spectrin alpha, erythrocytic 1)
more info ...
Allele / Splice: Spta1Tn(sb-T2/Bart3)2.315Mcwi  
Genetic Models: F344-Spta1Tn(sb-T2/Bart3)2.315Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01392,264,231 - 92,340,091 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1392,264,231 - 92,340,083 (+)Ensembl
Rnor_5.01396,782,387 - 96,860,327 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41389,951,924 - 90,028,592 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11390,140,807 - 90,217,468 (+)NCBI
Celera1385,806,253 - 85,882,378 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Spta1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305194
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.