Spta1 (spectrin alpha, erythrocytic 1) - Rat Genome Database

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Gene: Spta1 (spectrin alpha, erythrocytic 1) Mus musculus
Analyze
Symbol: Spta1
Name: spectrin alpha, erythrocytic 1
RGD ID: 1313078
MGI Page MGI
Description: Predicted to have actin binding activity and calcium ion binding activity. Involved in several processes, including lymphocyte homeostasis; porphyrin-containing compound biosynthetic process; and positive regulation of T cell proliferation. Localizes to cortical actin cytoskeleton; membrane; and spectrin-associated cytoskeleton. Is expressed in liver; liver left lobe; and liver right lobe. Used to study hereditary spherocytosis type 1; hereditary spherocytosis type 3; and sickle cell anemia. Human ortholog(s) of this gene implicated in hereditary spherocytosis and hereditary spherocytosis type 3. Orthologous to human SPTA1 (spectrin alpha, erythrocytic 1); INTERACTS WITH 1,2-dichloroethane; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AF093576; AI451697; alpha-spectrin 1, erythroid; eryth; erythroid alpha-spectrin; ha; hemolytic anemia; ih; ihj; neuroscience mutagenesis facility, 4; nmf4; S; Sp; spectrin alpha 1; spectrin alpha chain, erythrocyte; spectrin alpha chain, erythrocytic 1; sph; spherocytosis; Spna-1; Spna1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,000,305 - 174,076,015 (+)NCBIGRCm39mm39
GRCm39 Ensembl1174,000,342 - 174,076,016 (+)Ensembl
GRCm381174,172,739 - 174,248,449 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,172,776 - 174,248,450 (+)EnsemblGRCm38mm10GRCm38
MGSCv371176,102,907 - 176,178,580 (+)NCBIGRCm37mm9NCBIm37
MGSCv361176,009,543 - 176,084,742 (+)NCBImm8
MGSCv361175,481,229 - 175,556,592 (+)NCBImm8
Celera1181,280,976 - 181,363,312 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map180.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal bone marrow cell number  (IAGP)
abnormal bone marrow morphology  (IEA)
abnormal brain morphology  (IAGP)
abnormal cardiac thrombosis  (IAGP)
abnormal erythrocyte morphology  (IAGP)
abnormal erythrocyte osmotic lysis  (IAGP)
abnormal erythrocyte physiology  (IAGP)
abnormal erythropoiesis  (IAGP)
abnormal feces composition  (IEA)
abnormal fertility/fecundity  (IEA)
abnormal liver morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal lymph node cell ratio  (IAGP)
abnormal maternal nurturing  (IEA)
abnormal pulmonary alveolus wall morphology  (IAGP)
abnormal red blood cell deformability  (IAGP)
abnormal reticulocyte morphology  (IAGP)
abnormal skin pigmentation  (IEA)
abnormal spleen morphology  (IAGP)
abnormal splenic cell ratio  (IAGP)
abnormal thrombosis  (IAGP)
alveolitis  (IAGP)
anemia  (IAGP)
anisocytosis  (IAGP)
anisopoikilocytosis  (IAGP)
blood vessel congestion  (IAGP)
cardiac hypertrophy  (IAGP)
decreased body size  (IAGP)
decreased cellular hemoglobin content  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased hematocrit  (IAGP)
decreased hemoglobin content  (IAGP)
decreased mean corpuscular hemoglobin concentration  (IAGP)
decreased mean corpuscular volume  (IEA)
decreased spleen iron level  (IAGP)
decreased susceptibility to parasitic infection  (IAGP)
delayed hair appearance  (IEA)
dilated liver sinusoidal spaces  (IAGP)
elliptocytosis  (IAGP)
enlarged heart  (IAGP)
enlarged liver  (IAGP)
enlarged spleen  (IAGP)
erythroblastosis  (IAGP)
extramedullary hematopoiesis  (IAGP)
focal hepatic necrosis  (IAGP)
gallstones  (IAGP)
glomerulonephritis  (IAGP)
hemolysis  (IAGP)
hemolytic anemia  (IAGP)
hemosiderosis  (IAGP)
hypochromic microcytic anemia  (IEA)
increased B cell number  (IAGP)
increased B cell proliferation  (IAGP)
increased bone marrow cell number  (IAGP)
increased CD4-positive, alpha beta T cell number  (IAGP)
increased CD8-positive, alpha-beta T cell number  (IAGP)
increased circulating bilirubin level  (IAGP)
increased circulating iron level  (IAGP)
increased erythrocyte clearance  (IAGP)
increased erythrocyte osmotic fragility  (IAGP)
increased erythrocyte protoporphyrin level  (IAGP)
increased erythroid progenitor cell number  (IAGP)
increased heart rate  (IEA)
increased IgA level  (IAGP)
increased IgG level  (IAGP)
increased kidney iron level  (IAGP)
increased leukocyte cell number  (IAGP)
increased liver iron level  (IAGP)
increased lymphocyte cell number  (IAGP)
increased mean corpuscular volume  (IAGP)
increased monocyte cell number  (IAGP)
increased neutrophil cell number  (IAGP)
increased nucleated erythrocyte cell number  (IAGP)
increased spleen weight  (IAGP)
increased startle reflex  (IEA)
increased susceptibility to bacterial infection  (IAGP)
increased T cell number  (IAGP)
increased T cell proliferation  (IAGP)
infertility  (IAGP)
interstitial pneumonia  (IAGP)
jaundice  (IAGP)
liver degeneration  (IAGP)
liver vascular congestion  (IAGP)
low mean erythrocyte cell number  (IAGP)
lymph node hyperplasia  (IAGP)
macrocytosis  (IAGP)
microcytic anemia  (IEA)
microcytosis  (IAGP)
myocardium necrosis  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IEA)
pallor  (IAGP)
poikilocytosis  (IAGP)
polychromatophilia  (IAGP)
postnatal lethality  (IEA)
postnatal lethality, complete penetrance  (IEA)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IEA)
preweaning lethality, complete penetrance  (IEA)
preweaning lethality, incomplete penetrance  (IAGP)
pulmonary fibrosis  (IAGP)
reduced female fertility  (IEA)
renal necrosis  (IAGP)
renal tubular necrosis  (IAGP)
reticulocytosis  (IAGP)
schistocytosis  (IAGP)
shortened RR interval  (IEA)
spherocytosis  (IAGP)
tubular nephritis  (IAGP)
References

Additional References at PubMed
PMID:658175   PMID:1301170   PMID:1356891   PMID:1385865   PMID:1617226   PMID:1672660   PMID:1676977   PMID:1693656   PMID:1832936   PMID:1934076   PMID:1970330   PMID:2474894  
PMID:2476388   PMID:2499515   PMID:2570566   PMID:2574151   PMID:2591369   PMID:2842249   PMID:2885153   PMID:2885848   PMID:2894402   PMID:2895697   PMID:2971731   PMID:2987946  
PMID:3000887   PMID:3148667   PMID:3186715   PMID:3384439   PMID:3416634   PMID:3862089   PMID:4404581   PMID:4596202   PMID:6234993   PMID:6763106   PMID:6841965   PMID:7059672  
PMID:7492791   PMID:7517397   PMID:7607671   PMID:7684329   PMID:8195289   PMID:8288233   PMID:8355480   PMID:8390965   PMID:8422330   PMID:8530024   PMID:8563167   PMID:8613143  
PMID:8827514   PMID:9177772   PMID:9207740   PMID:9250876   PMID:9367690   PMID:9373273   PMID:9933565   PMID:10051400   PMID:10349636   PMID:10491617   PMID:10497278   PMID:10772878  
PMID:10862698   PMID:11042159   PMID:11076861   PMID:11084649   PMID:11217851   PMID:11829488   PMID:12393645   PMID:12466851   PMID:12477932   PMID:12904583   PMID:14451913   PMID:14757431  
PMID:16141072   PMID:16141073   PMID:16728274   PMID:16959763   PMID:18477769   PMID:18698006   PMID:18723693   PMID:20016102   PMID:20056793   PMID:20585040   PMID:20696915   PMID:20886612  
PMID:21267068   PMID:21406181   PMID:21566095   PMID:21677750   PMID:21752934   PMID:22159418   PMID:22163289   PMID:23125208   PMID:25218921   PMID:25305142   PMID:25830635   PMID:27848995  
PMID:28446510   PMID:28701737   PMID:29720258   PMID:32325033   PMID:32581705   PMID:32663195  


Genomics

Comparative Map Data
Spta1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,000,305 - 174,076,015 (+)NCBIGRCm39mm39
GRCm39 Ensembl1174,000,342 - 174,076,016 (+)Ensembl
GRCm381174,172,739 - 174,248,449 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,172,776 - 174,248,450 (+)EnsemblGRCm38mm10GRCm38
MGSCv371176,102,907 - 176,178,580 (+)NCBIGRCm37mm9NCBIm37
MGSCv361176,009,543 - 176,084,742 (+)NCBImm8
MGSCv361175,481,229 - 175,556,592 (+)NCBImm8
Celera1181,280,976 - 181,363,312 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map180.97NCBI
SPTA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1158,610,704 - 158,686,715 (-)EnsemblGRCh38hg38GRCh38
GRCh381158,610,498 - 158,686,715 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371158,580,494 - 158,656,505 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,847,120 - 156,923,130 (-)NCBINCBI36hg18NCBI36
Build 341155,393,568 - 155,469,561NCBI
Celera1131,651,547 - 131,727,219 (-)NCBI
Cytogenetic Map1q23.1NCBI
HuRef1129,938,262 - 130,013,934 (-)NCBIHuRef
CHM1_11159,976,850 - 160,052,530 (-)NCBICHM1_1
Spta1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21386,203,504 - 86,279,371 (+)NCBI
Rnor_6.0 Ensembl1392,264,231 - 92,340,083 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01392,264,231 - 92,340,091 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01396,782,387 - 96,860,327 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41389,951,924 - 90,028,592 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11390,140,807 - 90,217,468 (+)NCBI
Celera1385,806,253 - 85,882,378 (+)NCBICelera
Cytogenetic Map13q24NCBI
Spta1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546810,472,671 - 10,545,313 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546810,472,601 - 10,545,402 (-)NCBIChiLan1.0ChiLan1.0
SPTA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11137,760,188 - 137,836,131 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1137,760,942 - 137,835,927 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01133,969,717 - 134,045,301 (-)NCBIMhudiblu_PPA_v0panPan3
SPTA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13823,052,046 - 23,118,933 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3823,051,563 - 23,118,966 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3823,074,219 - 23,141,493 (+)NCBI
ROS_Cfam_1.03823,183,707 - 23,251,018 (+)NCBI
UMICH_Zoey_3.13822,946,752 - 23,013,687 (+)NCBI
UNSW_CanFamBas_1.03823,481,482 - 23,548,479 (+)NCBI
UU_Cfam_GSD_1.03823,912,752 - 23,979,956 (+)NCBI
Spta1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050584,995,049 - 5,068,389 (-)NCBI
SpeTri2.0NW_0049367401,686,218 - 1,759,083 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPTA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl491,485,067 - 91,640,063 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1491,573,470 - 91,640,057 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2499,567,778 - 99,634,336 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPTA1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1205,238,246 - 5,314,204 (+)NCBI
ChlSab1.1 Ensembl205,238,447 - 5,313,887 (+)Ensembl
Vero_WHO_p1.0NW_0236660384,407,178 - 4,482,460 (+)NCBI
Spta1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247942,638,605 - 2,715,934 (-)NCBI

Position Markers
AI451697  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,248,263 - 174,248,390UniSTSGRCm38
MGSCv371176,178,394 - 176,178,521UniSTSGRCm37
Celera1181,363,126 - 181,363,253UniSTS
Cytogenetic Map1H3UniSTS
cM Map195.4UniSTS
Whitehead/MRC_RH12191.93UniSTS
AF093576  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,247,504 - 174,247,624UniSTSGRCm38
MGSCv371176,177,635 - 176,177,755UniSTSGRCm37
Celera1181,362,370 - 181,362,490UniSTS
Cytogenetic Map1H3UniSTS
cM Map195.4UniSTS
Whitehead/MRC_RH12191.73UniSTS
Spna1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,247,340 - 174,247,533UniSTSGRCm38
MGSCv371176,177,471 - 176,177,664UniSTSGRCm37
Celera1181,362,206 - 181,362,399UniSTS
Cytogenetic Map1H3UniSTS
cM Map195.2UniSTS
cM Map180.97UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301652Cpfd2_mcerebellum pattern fissures (mouse)Not determined1172571254195471971Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
1301467Pcir1_mperiosteal circumference 1 (mouse)Not determined1141405603175405702Mouse
1300934Cfbw1_mcystic fibrosis body weight 1 (mouse)Not determined1145317638179317756Mouse
1300948Fglu2_mfasting glucose 2 (mouse)Not determined1157628733191628870Mouse
1301866Cplaq3_mcircadian period of locomotor activity 3 (mouse)Not determined1155893961189895041Mouse
1301189Lmr8_mleishmaniasis resistance 8 (mouse)Not determined1156774467189571420Mouse
1301191Stia1_mserum transfer induced arthritis 1 (mouse)Not determined1141405603175405702Mouse
1301565Mnotch_mmodifier of Notch (mouse)Not determined1157628733191628870Mouse
1301596Elnt_mescape latencies during navigation task (mouse)Not determined1162317638194429220Mouse
1301602Bslm4_mbasal locomotor activity 4 (mouse)Not determined1157628733191628870Mouse
1558720Bpq8_mblood pressure QTL 8 (mouse)Not determined1143457095177457233Mouse
1301614Cgnz1_mchronic glomerulonephritis in NZM 1 (mouse)Not determined1152211172186211344Mouse
1559024Zit1_mzinc induced tolerance 1 (mouse)Not determined1167730317195471971Mouse
1302158Fembrs5_mfemur breaking strength 5 (mouse)Not determined1167730317195471971Mouse
1558802Skmw6_mskeletal muscle weight 6 (mouse)Not determined1168222387195471971Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112081092175641372Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159435007193435127Mouse
1300777Chol10_mcholesterol 10 (mouse)Not determined9148047933182048047Mouse
1300842Sle9_msystematic lupus erythematosus susceptibility 9 (mouse)Not determined1158641251192641372Mouse
1300888Berr1_mberghei resistance locus 1 (mouse)Not determined1164315658190802075Mouse
1301932Ssta2_msusceptibility to Salmonella typhimurium antigens 2 (mouse)Not determined1155888654189888802Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150317922188627115Mouse
4141483Femwf7_mfemur work to failure 7 (mouse)Not determined167730317195471971Mouse
4141233Femwf12_mfemur work to failure 12 (mouse)Not determined141405603175405702Mouse
1302132Pbw1_mpentobarbital withdrawal QTL 1 (mouse)Not determined1156004198190004325Mouse
1300571Opfa_mopen field activity (mouse)Not determined1144703778178704023Mouse
1300727Mptp1_mMPTP sensitivity 1 (mouse)Not determined1171804480192998742Mouse
1300732Melm2_mmelanoma modifier 2 (mouse)Not determined1157628733191628870Mouse
1300745Gvhd1_mgraft-versus-host disease 1 (mouse)Not determined1157628733191628870Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150317922188627115Mouse
1301016Szs1_mseizure susceptibility 1 (mouse)Not determined1171051174174628870Mouse
1301025Lbw7_mlupus NZB x NZW 7 (mouse)Not determined1152211172186211344Mouse
1301385Radpf2_mradiation pulmonary fibrosis 2 (mouse)Not determined1147249520183092234Mouse
1357732Tbbmd1_mtotal body bone mineral density 1 (mouse)Not determined1172250913195471971Mouse
1357889Lprq3_mlipoprotein QTL 3 (mouse)Not determined1152211172186211344Mouse
4141244Bmd5c_mbone mineral density 5c (mouse)Not determined155699229189699330Mouse
4141245Cq2_mcholesterol QTL 2 (mouse)Not determined1157628733191628870Mouse
4141346Skmw12_mskeletal muscle weight 12 (mouse)Not determined150929168184929353Mouse
1301333Mop3_mmorphine preference 3 (mouse)Not determined1167929168189571420Mouse
1301339Hdlq15_mHDL QTL 15 (mouse)Not determined1166092111195471971Mouse
1301202Yaa4_mY-linked autoimmune acceleration 4 (mouse)Not determined1158641251192641372Mouse
1301216Cbm1_mcerebellum weight 1 (mouse)Not determined1157628733191628870Mouse
1357854Sle16_msystematic lupus erythematosus susceptibility 16 (mouse)Not determined1169211172177550021Mouse
1301251Scc3_mcolon tumor susceptibility 3 (mouse)Not determined1168481626195471971Mouse
1301122Cd8mts1_mCD8 T memory cell subset 1 (mouse)Not determined1156004198190004325Mouse
1301132Mors1_mmodifier of obesity related sterility 1 (mouse)Not determined1170647303195471971Mouse
1301134Bmd1_mbone mineral density 1 (mouse)Not determined1156774467189571420Mouse
1301151Hdlq14_mHDL QTL 14 (mouse)Not determined1142661973176662164Mouse
1301164Tir3c_mtrypansomiasis infection response 3c (mouse)Not determined1154804480188804689Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147249520189251027Mouse
4141165Bglu3_mblood glucose level 3 (mouse)Not determined156004198190004325Mouse
1301301Sle1_msystemic lupus erythmatosus susceptibility 1 (mouse)Not determined1152211172186211344Mouse
1301309Emo1_memotionality 1 (mouse)Not determined1163149528186261999Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160285202194285317Mouse
1300969Sluc5_msusceptibility to lung cancer 5 (mouse)Not determined1151358674185358833Mouse
1301619Cafq1_mcaffeine metabolism QTL 1 (mouse)Not determined1155888654189888802Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161373696195373830Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150317922188627115Mouse
4142119Bpq21_mblood pressure QTL 21 (mouse)Not determined1152211172186211344Mouse
4142149Ctex_mCtla4 expression QTL (mouse)Not determined1153681660175641372Mouse
4142159Nba2_mNew Zealand Black autoimmunity 2 (mouse)Not determined152007542186007711Mouse
4142182Shali5_msurvival time to hyperoxic acute lung injury 5 (mouse)Not determined155706491186261999Mouse
4141554Cfmq1_mcystic fibrosis modifier QTL 1 (mouse)Not determined1152211172186211344Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
4142389Scfr1_mstem cell frequency regulator 1 (mouse)Not determined171804480189571420Mouse
10043863Swrl5_mSWR lupus locus 5 (mouse)Not determined1172571254195471971Mouse
10043899Hdlq99_mHDL QTL 99 (mouse)Not determined1148047933182048047Mouse
10043963Obq25_mobesity QTL 25 (mouse)Not determined1154582944188582944Mouse
10402498Lmr20_mleishmaniasis resistance 20 (mouse)Not determined1158641251192641372Mouse
10412074Nhdlt1_mnon-HDL cholesterol and triglyceride levels 1 (mouse)Not determined1153848421187848536Mouse
10054490Opefa_mopen field activity (mouse)Not determined1153885284187885284Mouse
10045887Cplaq13_mcircadian period of locomotor activity 13 (mouse)Not determined1173004198181573094Mouse
10054270Nba10_mNew Zealand Black autoimmunity 10 (mouse)Not determined1152919071186706423Mouse
10054271Nba9_mNew Zealand Black autoimmunity 9 (mouse)Not determined1155698056189699966Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1104005680191493284Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
10412205Bbaa30_mB.burgdorferi-associated arthritis 30 (mouse)Not determined1169211172174628870Mouse
4141878Qrr1_mQTL rich region on chromosome 1 (mouse)Not determined171051174175492500Mouse
4142014Wbcq5_mwhite blood cell quantitative locus 5 (mouse)Not determined1141267440175267586Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128800000181500000Mouse
11049575Lmr8b_mleishmaniasis resistance 8b (mouse)1172571254195471971Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117600000180000000Mouse
11059558Lmr20c_mleishmaniasis resistance 20c (mouse)1158641251192641372Mouse
11059557Lmr20a_mleishmaniasis resistance 20a (mouse)1158641251192641372Mouse
12791001Aath6_maortic arch atherosclerosis 6 (mouse)1147391821181391821Mouse
11081167Tir8_mtrypanosome infection response 8 (mouse)1155888654189888802Mouse
12790996Aath2_maortic arch atherosclerosis 2 (mouse)1145250061179250061Mouse
12880426V25Dq2_mvitamin D inactive form serum level QTL 2 (mouse)1172800000195471971Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160269591194269591Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160269591194269591Mouse
11251722Ewc1_methanol withdrawal and consumption 1 (mouse)1152305175186305175Mouse
13207571Tcq11_mtotal cholesterol QTL 11 (mouse)1169310000179820000Mouse
12792983Liq1_mlimb inflammation QTL 1 (mouse)1167758517191493284Mouse
13464138Hdlq107_mHDL QTL 107 (mouse)1152305175186305175Mouse
12790984Pcho7_mplasma cholesterol 7 (mouse)1147391821181391821Mouse
12910521Scgq1_mspontaneous crescentic glomerulonephritis QTL 1 (mouse)1156774467176435127Mouse
11533913Rd6m1_mretinal degeneration 6 modifier 1 (mouse)1141405603175405702Mouse
12904957Gmmq1_mgastrocnemius muscle mass QTL 1 (mouse)1155175373189175373Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
11537365Cnes4_mC. neoformans susceptibility locus 4 (mouse)1144621573178621573Mouse
12904936Edlmmq1_mextensor digitorum longus muscle mass QTL 1 (mouse)1155175373189175373Mouse
12880429V25Dq1_mvitamin D inactive form serum level QTL 1 (mouse)1172900000195471971Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
12904944Tammq1_mtibialis anterior muscle mass QTL 1 (mouse)1155175373189175373Mouse
11059556Lmr20b_mleishmaniasis resistance 20b (mouse)1158641251192641372Mouse
10766456Sle21_msystematic lupus erythematosus susceptibility 21 (mouse)1156004198190004325Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:388
Count of miRNA genes:262
Interacting mature miRNAs:290
Transcripts:ENSMUST00000027817, ENSMUST00000156092
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000027817   ⟹   ENSMUSP00000027817
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1174,172,776 - 174,248,450 (+)Ensembl
RefSeq Acc Id: ENSMUST00000156092
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1174,215,485 - 174,247,556 (+)Ensembl
RefSeq Acc Id: NM_011465   ⟹   NP_035595
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,000,342 - 174,076,015 (+)NCBI
GRCm381174,172,776 - 174,248,449 (+)ENTREZGENE
MGSCv371176,102,907 - 176,178,580 (+)RGD
Celera1181,280,976 - 181,363,312 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_001783648
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,000,305 - 174,073,243 (+)NCBI
GRCm381174,172,739 - 174,245,677 (+)NCBI
Sequence:
RefSeq Acc Id: XR_373600
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,000,305 - 174,073,243 (+)NCBI
GRCm381174,172,739 - 174,245,677 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035595   ⟸   NM_011465
- UniProtKB: P08032 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000027817   ⟸   ENSMUST00000027817
Protein Domains
EF-hand   SH3

Promoters
RGD ID:6875828
Promoter ID:EPDNEW_M1365
Type:initiation region
Name:Spta1_1
Description:Mus musculus spectrin alpha, erythrocytic 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381174,172,828 - 174,172,888EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98385 AgrOrtholog
Ensembl Genes ENSMUSG00000026532 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000027817 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000027817 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand_Ca_insen UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
  Spectrin/alpha-actinin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spectrin_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20739 UniProtKB/Swiss-Prot
MGD MGI:98385 ENTREZGENE
NCBI Gene 20739 ENTREZGENE
Pfam EFhand_Ca_insen UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_1 UniProtKB/Swiss-Prot
  Spectrin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Spta1 PhenoGen
PROSITE EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot
SMART SH3 UniProtKB/Swiss-Prot
  SPEC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50044 UniProtKB/Swiss-Prot
UniProt P08032 ENTREZGENE
  Q3UQ30_MOUSE UniProtKB/TrEMBL
  Q8C3F9_MOUSE UniProtKB/TrEMBL
  SPTA1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary B2RWX6 UniProtKB/Swiss-Prot
  P97502 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-12-25 Spta1  spectrin alpha, erythrocytic 1  Spna1  spectrin alpha 1  Symbol and/or name change 5135510 APPROVED