Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Pkp1 (plakophilin 1) Rattus norvegicus
Analyze
Symbol: Pkp1
Name: plakophilin 1
Description: Predicted to have cadherin binding activity and lamin binding activity. Predicted to be involved in several processes, including cell-cell junction assembly; intermediate filament bundle assembly; and negative regulation of mRNA catabolic process. Predicted to localize to several cellular components, including the cell-cell adherens junction; desmosome; and messenger ribonucleoprotein complex. Human ortholog(s) of this gene implicated in ectodermal dysplasia. Orthologous to human PKP1 (plakophilin 1); INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC304822; plakophilin-1
Orthologs:
Homo sapiens (human) : PKP1 (plakophilin 1)  HGNC  Alliance
Mus musculus (house mouse) : Pkp1 (plakophilin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pkp1 (plakophilin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PKP1 (plakophilin 1)
Canis lupus familiaris (dog) : PKP1 (plakophilin 1 (ectodermal dysplasia/skin fragility syndrome))
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pkp1 (plakophilin 1)
Sus scrofa (pig) : PKP1 (plakophilin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01352,705,174 - 52,753,089 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1352,705,174 - 52,752,997 (-)Ensembl
Rnor_5.01357,753,232 - 57,800,892 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41348,910,028 - 48,958,983 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11348,924,070 - 48,973,030 (-)NCBI
Celera1347,626,371 - 47,674,244 (-)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pkp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307472
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.