Rgs8 (regulator of G-protein signaling 8) - Rat Genome Database
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Gene: Rgs8 (regulator of G-protein signaling 8) Rattus norvegicus
Analyze
Symbol: Rgs8
Name: regulator of G-protein signaling 8
RGD ID: 3571
Description: Exhibits G-protein alpha-subunit binding activity and GTPase activator activity. Involved in several processes, including G protein-coupled acetylcholine receptor signaling pathway; positive regulation of GTPase activity; and response to amphetamine. Localizes to several cellular components, including dendrite; extrinsic component of cytoplasmic side of plasma membrane; and neuronal cell body membrane. Orthologous to human RGS8 (regulator of G protein signaling 8); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC105444
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21365,804,703 - 65,848,953 (+)NCBI
Rnor_6.0 Ensembl1371,086,745 - 71,141,075 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01371,086,654 - 71,141,820 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01376,051,812 - 76,105,170 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41368,735,814 - 68,766,956 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11368,749,893 - 68,781,036 (+)NCBI
Celera1365,717,445 - 65,747,668 (+)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:12477932   PMID:13679049   PMID:15489334   PMID:18434541  


Genomics

Comparative Map Data
Rgs8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21365,804,703 - 65,848,953 (+)NCBI
Rnor_6.0 Ensembl1371,086,745 - 71,141,075 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01371,086,654 - 71,141,820 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01376,051,812 - 76,105,170 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41368,735,814 - 68,766,956 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11368,749,893 - 68,781,036 (+)NCBI
Celera1365,717,445 - 65,747,668 (+)NCBICelera
Cytogenetic Map13q21NCBI
RGS8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1182,641,816 - 182,684,576 (-)EnsemblGRCh38hg38GRCh38
GRCh381182,641,814 - 182,753,293 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371182,610,953 - 182,721,511 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371182,613,036 - 182,653,502 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361180,882,415 - 180,908,690 (-)NCBINCBI36hg18NCBI36
Build 341179,347,448 - 179,373,706NCBI
Celera1155,727,019 - 155,753,291 (-)NCBI
Cytogenetic Map1q25.3NCBI
HuRef1153,852,220 - 153,878,494 (-)NCBIHuRef
CHM1_11184,034,480 - 184,065,602 (-)NCBICHM1_1
Rgs8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,528,612 - 153,573,415 (+)NCBIGRCm39mm39
GRCm381153,652,959 - 153,697,669 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,653,025 - 153,700,323 (+)EnsemblGRCm38mm10GRCm38
MGSCv371155,500,167 - 155,544,795 (+)NCBIGRCm37mm9NCBIm37
MGSCv361155,415,255 - 155,459,883 (+)NCBImm8
Celera1156,084,491 - 156,129,267 (+)NCBICelera
Cytogenetic Map1G3NCBI
cM Map165.41NCBI
Rgs8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540621,482,810 - 21,523,674 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540621,482,810 - 21,523,518 (-)NCBIChiLan1.0ChiLan1.0
RGS8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11161,811,997 - 161,847,846 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,813,540 - 161,855,027 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01158,160,368 - 158,268,521 (-)NCBIMhudiblu_PPA_v0panPan3
RGS8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl716,053,946 - 16,080,388 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1716,053,946 - 16,081,661 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Rgs8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364817,077,345 - 7,115,350 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9123,953,290 - 124,093,539 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19123,937,721 - 124,053,927 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29136,138,527 - 136,261,508 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RGS8
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12546,683,978 - 46,724,205 (+)NCBI
ChlSab1.1 Ensembl2546,683,783 - 46,726,543 (+)Ensembl
Rgs8
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462481411,176,559 - 11,208,684 (+)NCBI

Position Markers
D13Wox23  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01371,139,243 - 71,139,445NCBIRnor6.0
Rnor_5.01376,104,495 - 76,104,697UniSTSRnor5.0
RGSC_v3.41368,766,526 - 68,766,728UniSTSRGSC3.4
Celera1365,747,238 - 65,747,440UniSTS
Cytogenetic Map13q21UniSTS
BF387596  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01371,137,625 - 71,137,821NCBIRnor6.0
Rnor_5.01376,102,877 - 76,103,073UniSTSRnor5.0
RGSC_v3.41368,764,908 - 68,765,104UniSTSRGSC3.4
Celera1365,745,620 - 65,745,816UniSTS
RH 3.4 Map13340.1UniSTS
Cytogenetic Map13q21UniSTS
BF415829  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01371,116,207 - 71,116,301NCBIRnor6.0
Rnor_5.01376,081,459 - 76,081,553UniSTSRnor5.0
RGSC_v3.41368,744,556 - 68,744,650UniSTSRGSC3.4
Celera1365,726,175 - 65,726,269UniSTS
RH 3.4 Map13339.9UniSTS
Cytogenetic Map13q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131107975663Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1312193394108478121Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1324502279108770533Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132800833873008338Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132858445273584452Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132907693474076934Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132907693474076934Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1335301263107975663Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133614753399968921Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133734634882346348Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133937292784372927Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133950130093652524Rat
4889861Pur29Proteinuria QTL 2913.80.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)134231074486833540Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)134231074487310744Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134357571788575717Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134567662990676629Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135108098996080989Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)135156924896569248Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)135157782490675199Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1357903612102903612Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1362975663107975663Rat
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136361128379034003Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)136450135182995671Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136500824591629354Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1366971778111971778Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:503
Count of miRNA genes:261
Interacting mature miRNAs:338
Transcripts:ENSRNOT00000003239
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 68
Low 3 1 3 1 6 26 4
Below cutoff 3 30 28 14 16 14 8 8 27 15 7 8

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_019344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB006013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U32432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000003239   ⟹   ENSRNOP00000003239
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1371,107,465 - 71,139,672 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083366   ⟹   ENSRNOP00000073985
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1371,086,745 - 71,141,075 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000088329   ⟹   ENSRNOP00000074194
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1371,110,064 - 71,137,018 (+)Ensembl
RefSeq Acc Id: NM_019344   ⟹   NP_062217
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,816,434 - 65,846,808 (+)NCBI
Rnor_6.01371,107,465 - 71,139,673 (+)NCBI
Rnor_5.01376,051,812 - 76,105,170 (+)NCBI
RGSC_v3.41368,735,814 - 68,766,956 (+)RGD
Celera1365,717,445 - 65,747,668 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250015   ⟹   XP_006250077
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,804,703 - 65,848,953 (+)NCBI
Rnor_6.01371,086,654 - 71,141,820 (+)NCBI
Rnor_5.01376,051,812 - 76,105,170 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250016   ⟹   XP_006250078
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,816,764 - 65,848,953 (+)NCBI
Rnor_6.01371,107,707 - 71,141,820 (+)NCBI
Rnor_5.01376,051,812 - 76,105,170 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039091033   ⟹   XP_038946961
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,804,930 - 65,848,953 (+)NCBI
RefSeq Acc Id: XM_039091035   ⟹   XP_038946963
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,804,893 - 65,848,953 (+)NCBI
RefSeq Acc Id: XM_039091036   ⟹   XP_038946964
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,816,261 - 65,848,953 (+)NCBI
RefSeq Acc Id: XM_039091037   ⟹   XP_038946965
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,816,036 - 65,848,953 (+)NCBI
RefSeq Acc Id: XM_039091038   ⟹   XP_038946966
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,816,000 - 65,848,953 (+)NCBI
RefSeq Acc Id: XM_039091039   ⟹   XP_038946967
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,816,241 - 65,848,953 (+)NCBI
RefSeq Acc Id: XM_039091040   ⟹   XP_038946968
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,804,886 - 65,848,953 (+)NCBI
RefSeq Acc Id: XM_039091041   ⟹   XP_038946969
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,816,705 - 65,848,953 (+)NCBI
RefSeq Acc Id: XM_039091042   ⟹   XP_038946970
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21365,816,643 - 65,848,953 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_062217   ⟸   NM_019344
- UniProtKB: P49804 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006250077   ⟸   XM_006250015
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K6Y1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250078   ⟸   XM_006250016
- Peptide Label: isoform X2
- UniProtKB: P49804 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073985   ⟸   ENSRNOT00000083366
RefSeq Acc Id: ENSRNOP00000003239   ⟸   ENSRNOT00000003239
RefSeq Acc Id: ENSRNOP00000074194   ⟸   ENSRNOT00000088329
RefSeq Acc Id: XP_038946968   ⟸   XM_039091040
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038946963   ⟸   XM_039091035
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038946961   ⟸   XM_039091033
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038946966   ⟸   XM_039091038
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038946965   ⟸   XM_039091037
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038946967   ⟸   XM_039091039
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038946964   ⟸   XM_039091036
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038946970   ⟸   XM_039091042
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038946969   ⟸   XM_039091041
- Peptide Label: isoform X3
Protein Domains
RGS

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3571 AgrOrtholog
Ensembl Genes ENSRNOG00000002369 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000003239 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000073985 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000074194 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003239 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000083366 UniProtKB/TrEMBL
  ENSRNOT00000088329 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.196.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7317138 IMAGE-MGC_LOAD
InterPro RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_RGS8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_subdom1/3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:54297 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105444 IMAGE-MGC_LOAD
NCBI Gene 54297 ENTREZGENE
PANTHER PTHR10845:SF147 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rgs8 PhenoGen
PRINTS RGSPROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48097 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC207322
UniProt A0A0G2K6Y1 ENTREZGENE, UniProtKB/TrEMBL
  P49804 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Rgs8  regulator of G-protein signaling 8      Name updated 70584 APPROVED