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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TNN mRNA] | CTD | PMID:31150632 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TNN mRNA | CTD | PMID:34747641 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | decreases expression | ISO | RGD:1314366 | 6480464 | 2 more ... | CTD | PMID:26705709 | 3-chloropropane-1,2-diol | increases expression | ISO | RGD:1314367 | 6480464 | alpha-Chlorohydrin results in increased expression of TNN mRNA | CTD | PMID:33187795 | 4,4'-sulfonyldiphenol | affects methylation | ISO | RGD:1314367 | 6480464 | bis(4-hydroxyphenyl)sulfone affects the methylation of TNN exon | CTD | PMID:33297965 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of TNN mRNA | CTD | PMID:24780913, PMID:25825206 | aflatoxin B1 | increases methylation | ISO | RGD:1314366 | 6480464 | Aflatoxin B1 results in increased methylation of TNN gene | CTD | PMID:27153756 | Aflatoxin B2 alpha | increases methylation | ISO | RGD:1314366 | 6480464 | aflatoxin B2 results in increased methylation of TNN exon | CTD | PMID:30157460 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of TNN mRNA | CTD | PMID:30779732 | belinostat | multiple interactions | ISO | RGD:1314366 | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNN mRNA | CTD | PMID:27188386 | benzo[a]pyrene | increases mutagenesis | ISO | RGD:1314366 | 6480464 | Benzo(a)pyrene results in increased mutagenesis of TNN gene | CTD | PMID:25435355 | benzo[a]pyrene | affects methylation | ISO | RGD:1314366 | 6480464 | Benzo(a)pyrene affects the methylation of TNN 5' UTR, Benzo(a)pyrene affects the methylation of TNN promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | RGD:1314367 | 6480464 | Benzo(a)pyrene results in decreased methylation of TNN exon, Benzo(a)pyrene results in decreased methylation of TNN intron | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | RGD:1314366 | 6480464 | Benzo(a)pyrene results in increased methylation of TNN 3' UTR | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | ISO | RGD:1314366 | 6480464 | benzo(e)pyrene results in increased methylation of TNN exon | CTD | PMID:30157460 | Benzo[ghi]perylene | increases expression | ISO | RGD:1314367 | 6480464 | 1, 12-benzoperylene results in increased expression of TNN mRNA | CTD | PMID:26377693 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TNN mRNA | CTD | PMID:25181051 more ... | calcitriol | decreases expression | ISO | RGD:1314366 | 6480464 | Calcitriol results in decreased expression of TNN mRNA | CTD | PMID:16002434 | carbon nanotube | decreases expression | ISO | RGD:1314367 | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of TNN mRNA | CTD | PMID:26033743 | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of TNN mRNA | CTD | PMID:26033743 | DDT | decreases methylation | EXP | | 6480464 | DDT results in decreased methylation of TNN gene | CTD | PMID:31682807 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of TNN mRNA | CTD | PMID:21266533 | dibutyl phthalate | increases expression | ISO | RGD:1314367 | 6480464 | Dibutyl Phthalate results in increased expression of TNN mRNA | CTD | PMID:21266533 | dioxygen | multiple interactions | ISO | RGD:1314367 | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of TNN mRNA | CTD | PMID:30529165 | dorsomorphin | multiple interactions | ISO | RGD:1314366 | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of TNN mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | RGD:1314366 | 6480464 | entinostat results in increased expression of TNN mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | RGD:1314366 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNN mRNA | CTD | PMID:27188386 | ethyl methanesulfonate | increases expression | ISO | RGD:1314366 | 6480464 | Ethyl Methanesulfonate results in increased expression of TNN mRNA | CTD | PMID:23649840 | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of TNN mRNA | CTD | PMID:34044035 | formaldehyde | increases expression | ISO | RGD:1314366 | 6480464 | Formaldehyde results in increased expression of TNN mRNA | CTD | PMID:23649840 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of TNN mRNA | CTD | PMID:27387713 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TNN mRNA | CTD | PMID:33387578 | isotretinoin | increases expression | ISO | RGD:1314366 | 6480464 | Isotretinoin results in increased expression of TNN mRNA | CTD | PMID:20436886 | manganese(II) chloride | decreases expression | EXP | | 6480464 | manganese chloride results in decreased expression of TNN mRNA | CTD | PMID:28801915 | manganese(II) chloride | increases methylation | EXP | | 6480464 | manganese chloride results in increased methylation of TNN gene | CTD | PMID:28801915 | methapyrilene | increases methylation | ISO | RGD:1314366 | 6480464 | Methapyrilene results in increased methylation of TNN exon | CTD | PMID:30157460 | methyl methanesulfonate | increases expression | ISO | RGD:1314366 | 6480464 | Methyl Methanesulfonate results in increased expression of TNN mRNA | CTD | PMID:23649840 | monocrotaline | increases expression | EXP | | 6480464 | Monocrotaline results in increased expression of TNN protein | CTD | PMID:24947524 | N-methyl-4-phenylpyridinium | decreases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of TNN mRNA | CTD | PMID:28801915 | nickel atom | decreases expression | ISO | RGD:1314366 | 6480464 | Nickel results in decreased expression of TNN mRNA | CTD | PMID:24768652, PMID:25583101 | ozone | multiple interactions | ISO | RGD:1314367 | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of TNN mRNA | CTD | PMID:34911549 | panobinostat | multiple interactions | ISO | RGD:1314366 | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNN mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | RGD:1314366 | 6480464 | panobinostat results in increased expression of TNN mRNA | CTD | PMID:26272509 | pentane-2,3-dione | increases expression | EXP | | 6480464 | 2, 3-pentanedione results in increased expression of TNN mRNA | CTD | PMID:25710175 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of TNN mRNA | CTD | PMID:27979718 | SB 431542 | multiple interactions | ISO | RGD:1314366 | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium fluoride | decreases expression | EXP | | 6480464 | Sodium Fluoride results in decreased expression of TNN mRNA | CTD | PMID:27257137 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TNN mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of TNN mRNA | CTD | PMID:31150632 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TNN mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | RGD:1314367 | 6480464 | titanium dioxide results in decreased expression of TNN mRNA | CTD | PMID:19464567 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of TNN mRNA | CTD | PMID:30012374 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of TNN mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | RGD:1314366 | 6480464 | trichostatin A results in increased expression of TNN mRNA | CTD | PMID:24935251 | trimellitic anhydride | increases expression | ISO | RGD:1314367 | 6480464 | trimellitic anhydride results in increased expression of TNN mRNA | CTD | PMID:19042947 | valproic acid | increases expression | ISO | RGD:1314366 | 6480464 | Valproic Acid results in increased expression of TNN mRNA | CTD | PMID:24383497, PMID:24935251 | vorinostat | increases expression | ISO | RGD:1314366 | 6480464 | vorinostat results in increased expression of TNN mRNA | CTD | PMID:26272509 | vorinostat | multiple interactions | ISO | RGD:1314366 | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNN mRNA | CTD | PMID:27188386 | |