Adss2 (adenylosuccinate synthase 2) - Rat Genome Database

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Gene: Adss2 (adenylosuccinate synthase 2) Rattus norvegicus
Analyze
Symbol: Adss2 (Ensembl: Adss)
Name: adenylosuccinate synthase 2 (Ensembl:adenylosuccinate synthase)
RGD ID: 1310508
Description: Enables adenylosuccinate synthase activity. Involved in several processes, including IMP metabolic process; aspartate metabolic process; and cellular response to electrical stimulus. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Biomarker of sarcoma. Orthologous to human ADSS2 (adenylosuccinate synthase 2); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: adenylosuccinate synthase; adenylosuccinate synthetase 2, non muscle; adenylosuccinate synthetase isozyme 2; adenylosuccinate synthetase, non muscle; Adss; LOC289276
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81392,301,302 - 92,331,638 (-)NCBIGRCr8
mRatBN7.21389,769,240 - 89,799,577 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1389,769,244 - 89,799,604 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1392,274,500 - 92,304,832 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01393,674,619 - 93,704,952 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01390,853,087 - 90,883,179 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01395,913,426 - 95,943,761 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1395,913,426 - 95,943,761 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013100,355,979 - 100,386,314 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41393,681,036 - 93,711,373 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11393,869,972 - 93,900,303 (-)NCBI
Celera1389,331,572 - 89,361,621 (-)NCBICelera
Cytogenetic Map13q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
mitochondrion  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Changes in isozymes of adenylosuccinate synthetase. Baugher BW, etal., Biochem Biophys Res Commun. 1980 May 14;94(1):123-9.
2. Metabolism of threo-beta-fluoroaspartate by H4 cells. Inhibition of adenylosuccinate lyase by fluoro analogs of its substrates. Casey PJ, etal., J Biol Chem. 1986 Oct 15;261(29):13637-42.
3. Importance of purine nucleotide cycle to energy production in skeletal muscle. Flanagan WF, etal., Am J Physiol. 1986 Nov;251(5 Pt 1):C795-802.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Adenylosuccinate synthetase: recent developments. Honzatko RB, etal., Adv Enzymol Relat Areas Mol Biol. 1999;73:57-102, ix-x.
7. Isozyme shift of adenylosuccinate synthase in rat and human neoplasms. Ikegami T, etal., Adv Exp Med Biol. 1989;253A:417-21.
8. Adenine nucleotide metabolism in hearts of diabetic rats. Comparison to diaphragm, liver, and kidney. Jenkins RL, etal., Diabetes. 1988 May;37(5):629-36.
9. Adenylosuccinate synthetase in rat liver: the existence of two types and their regulatory roles. Matsuda Y, etal., Biochem Biophys Res Commun. 1977 Sep 23;78(2):766-71.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Effect of acidosis and uninephrectomy on isozymes of adenylosuccinate synthetase in rat kidney. Tornheim K and Lowenstein LM, Biochim Biophys Acta. 1983 May 4;757(1):137-9.
15. Electrical stimulation of neonatal cardiac myocytes activates the NFAT3 and GATA4 pathways and up-regulates the adenylosuccinate synthetase 1 gene. Xia Y, etal., J Biol Chem. 2000 Jan 21;275(3):1855-63.
Additional References at PubMed
PMID:1592113   PMID:2004783   PMID:8308018   PMID:12482871   PMID:15786719   PMID:17347008   PMID:23533145  


Genomics

Comparative Map Data
Adss2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81392,301,302 - 92,331,638 (-)NCBIGRCr8
mRatBN7.21389,769,240 - 89,799,577 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1389,769,244 - 89,799,604 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1392,274,500 - 92,304,832 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01393,674,619 - 93,704,952 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01390,853,087 - 90,883,179 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01395,913,426 - 95,943,761 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1395,913,426 - 95,943,761 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013100,355,979 - 100,386,314 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41393,681,036 - 93,711,373 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11393,869,972 - 93,900,303 (-)NCBI
Celera1389,331,572 - 89,361,621 (-)NCBICelera
Cytogenetic Map13q25NCBI
ADSS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381244,408,494 - 244,452,060 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1244,408,494 - 244,451,909 (-)EnsemblGRCh38hg38GRCh38
GRCh371244,571,796 - 244,615,362 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361242,638,419 - 242,682,036 (-)NCBINCBI36Build 36hg18NCBI36
Build 341240,897,836 - 240,941,454NCBI
Celera1217,861,837 - 217,905,438 (-)NCBICelera
Cytogenetic Map1q44ENTREZGENE
HuRef1214,954,992 - 214,998,619 (-)NCBIHuRef
CHM1_11245,844,434 - 245,888,075 (-)NCBICHM1_1
T2T-CHM13v2.01243,824,815 - 243,868,543 (-)NCBIT2T-CHM13v2.0
Adss2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391177,590,742 - 177,624,064 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1177,590,528 - 177,624,077 (-)EnsemblGRCm39 Ensembl
GRCm381177,763,176 - 177,796,695 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1177,762,962 - 177,796,511 (-)EnsemblGRCm38mm10GRCm38
MGSCv371179,693,309 - 179,726,640 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361179,599,853 - 179,633,184 (-)NCBIMGSCv36mm8
Celera1184,815,169 - 184,848,493 (-)NCBICelera
Cytogenetic Map1H4NCBI
cM Map182.81NCBI
Adss2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554067,683,596 - 7,715,616 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554067,684,979 - 7,715,179 (-)NCBIChiLan1.0ChiLan1.0
ADSS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214,687,297 - 4,730,341 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114,909,338 - 4,952,688 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01220,020,480 - 220,063,658 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11225,401,544 - 225,444,984 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1225,401,544 - 225,444,984 (-)Ensemblpanpan1.1panPan2
ADSS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1735,440,250 - 35,477,470 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl735,440,676 - 35,476,795 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha734,914,701 - 34,951,923 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0735,267,843 - 35,305,065 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl735,267,844 - 35,304,386 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1735,103,992 - 35,141,205 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0735,120,419 - 35,155,914 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0735,385,151 - 35,422,371 (-)NCBIUU_Cfam_GSD_1.0
Adss2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934448,366,561 - 48,404,882 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365266,342,221 - 6,380,840 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365266,342,233 - 6,380,736 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADSS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1017,220,207 - 17,259,182 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11017,220,081 - 17,259,141 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21019,583,927 - 19,606,684 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADSS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12581,441,792 - 81,485,344 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2581,442,787 - 81,485,292 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605583,656,557 - 83,700,262 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adss2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477115,059,876 - 15,097,518 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477115,059,845 - 15,097,518 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Adss2
110 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:157
Count of miRNA genes:120
Interacting mature miRNAs:142
Transcripts:ENSRNOT00000005961
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat

Markers in Region
RH129208  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21389,769,325 - 89,769,523 (+)MAPPERmRatBN7.2
Rnor_6.01395,913,512 - 95,913,709NCBIRnor6.0
Rnor_5.013100,356,065 - 100,356,262UniSTSRnor5.0
RGSC_v3.41393,681,122 - 93,681,319UniSTSRGSC3.4
Celera1389,331,658 - 89,331,855UniSTS
Cytogenetic Map13q25UniSTS
RH142786  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21389,795,235 - 89,795,489 (+)MAPPERmRatBN7.2
Rnor_6.01395,939,421 - 95,939,674NCBIRnor6.0
Rnor_5.013100,381,974 - 100,382,227UniSTSRnor5.0
RGSC_v3.41393,707,032 - 93,707,285UniSTSRGSC3.4
Celera1389,357,307 - 89,357,560UniSTS
RH 3.4 Map13605.8UniSTS
Cytogenetic Map13q25UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 36 57 41 19 41 5 5 74 35 41 11 5
Low 7 3 6 3
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000005961   ⟹   ENSRNOP00000005961
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1389,769,244 - 89,799,604 (-)Ensembl
Rnor_6.0 Ensembl1395,913,426 - 95,943,761 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095288   ⟹   ENSRNOP00000082624
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1389,770,197 - 89,799,604 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100170   ⟹   ENSRNOP00000084186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1389,769,249 - 89,799,579 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111024   ⟹   ENSRNOP00000097735
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1389,769,244 - 89,799,604 (-)Ensembl
RefSeq Acc Id: NM_001105975   ⟹   NP_001099445
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,301,302 - 92,331,638 (-)NCBI
mRatBN7.21389,769,240 - 89,799,577 (-)NCBI
Rnor_6.01395,913,426 - 95,943,761 (-)NCBI
Rnor_5.013100,355,979 - 100,386,314 (-)NCBI
RGSC_v3.41393,681,036 - 93,711,373 (-)RGD
Celera1389,331,572 - 89,361,621 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001099445 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL94793 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005961
  ENSRNOP00000005961.5
  ENSRNOP00000082624.1
  ENSRNOP00000084186.1
  ENSRNOP00000097735.1
RefSeq Acc Id: NP_001099445   ⟸   NM_001105975
- UniProtKB: D4AEP0 (UniProtKB/TrEMBL),   A6JGD7 (UniProtKB/TrEMBL),   A0A8I6AT75 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005961   ⟸   ENSRNOT00000005961
RefSeq Acc Id: ENSRNOP00000082624   ⟸   ENSRNOT00000095288
RefSeq Acc Id: ENSRNOP00000084186   ⟸   ENSRNOT00000100170
RefSeq Acc Id: ENSRNOP00000097735   ⟸   ENSRNOT00000111024

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AEP0-F1-model_v2 AlphaFold D4AEP0 1-456 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699045
Promoter ID:EPDNEW_R9570
Type:initiation region
Name:Adss_1
Description:adenylosuccinate synthase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01395,943,742 - 95,943,802EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310508 AgrOrtholog
BioCyc Gene G2FUF-17181 BioCyc
BioCyc Pathway PWY-7219 [adenosine ribonucleotides de novo biosynthesis] BioCyc
BioCyc Pathway Image PWY-7219 BioCyc
Ensembl Genes ENSRNOG00000004481 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005961 ENTREZGENE
  ENSRNOT00000005961.6 UniProtKB/TrEMBL
  ENSRNOT00000095288.1 UniProtKB/TrEMBL
  ENSRNOT00000100170.1 UniProtKB/TrEMBL
  ENSRNOT00000111024.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.300.10 UniProtKB/TrEMBL
  3.40.440.10 UniProtKB/TrEMBL
  3.90.170.10 UniProtKB/TrEMBL
InterPro Adenylosuccin_syn_Lys_AS UniProtKB/TrEMBL
  Adenylosuccinate_synth_dom1 UniProtKB/TrEMBL
  Adenylosuccinate_synth_dom2 UniProtKB/TrEMBL
  Adenylosuccinate_synth_dom3 UniProtKB/TrEMBL
  Adenylosuccinate_synthase_AS UniProtKB/TrEMBL
  Adenylosuccinate_synthetase UniProtKB/TrEMBL
  AdSS_2_vert UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report rno:289276 UniProtKB/TrEMBL
NCBI Gene 289276 ENTREZGENE
PANTHER ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 UniProtKB/TrEMBL
  Asucc_synthtase UniProtKB/TrEMBL
Pfam Adenylsucc_synt UniProtKB/TrEMBL
PhenoGen Adss2 PhenoGen
PROSITE ADENYLOSUCCIN_SYN_1 UniProtKB/TrEMBL
  ADENYLOSUCCIN_SYN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004481 RatGTEx
SMART Adenylsucc_synt UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8I6AT75 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G7N1_RAT UniProtKB/TrEMBL
  A0A8I6GA01_RAT UniProtKB/TrEMBL
  A6JGD7 ENTREZGENE, UniProtKB/TrEMBL
  D4AEP0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-05 Adss2  adenylosuccinate synthase 2  Adss  adenylosuccinate synthase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Adss  adenylosuccinate synthase  Adss  adenylosuccinate synthetase, non muscle   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Adss  adenylosuccinate synthetase, non muscle   Adss_predicted  adenylosuccinate synthetase, non muscle (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Adss_predicted  adenylosuccinate synthetase, non muscle (predicted)  Adss2_predicted  adenylosuccinate synthetase 2, non muscle (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Adss2_predicted  adenylosuccinate synthetase 2, non muscle (predicted)      Symbol and Name status set to approved 70820 APPROVED