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Gene: Nr1i3 (nuclear receptor subfamily 1, group I, member 3) Rattus norvegicus
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Symbol: Nr1i3
Name: nuclear receptor subfamily 1, group I, member 3
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; nuclear receptor transcription coactivator activity; and transcription factor binding activity. Involved in osteoblast differentiation. Localizes to the cytoplasm and nucleus. Biomarker of cholestasis. Orthologous to human NR1I3 (nuclear receptor subfamily 1 group I member 3); INTERACTS WITH (+)-artemisinin; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CAR; constitutive androstane receptor; MGC108525; nuclear receptor constitutive active receptor; nuclear receptor subfamily 1 group I member 3; strain Fischer nuclear receptor (CAR)
Orthologs:
Allele / Splice: Nr1i3em1Sage  
Genetic Models: SD-Nr1i2em1Sage Nr1i3em1Sage SD-Nr1i2em1Sage Nr1i3em1Sage Ahrem1Sage SD-Nr1i3em1Sage
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01389,585,072 - 89,591,278 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01394,211,961 - 94,218,143 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,104,241 - 87,108,563 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11387,292,773 - 87,297,730 (+)NCBI
Celera1383,264,145 - 83,269,088 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nr1i3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621400
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.