Sdhc (succinate dehydrogenase complex subunit C) - Rat Genome Database

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Gene: Sdhc (succinate dehydrogenase complex subunit C) Rattus norvegicus
Analyze
Symbol: Sdhc
Name: succinate dehydrogenase complex subunit C
RGD ID: 1359454
Description: Predicted to enable heme binding activity. Predicted to be involved in mitochondrial electron transport, succinate to ubiquinone. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone). Human ortholog(s) of this gene implicated in Carney-Stratakis syndrome; gastrointestinal stromal tumor; lung non-small cell carcinoma; and paraganglioma. Orthologous to human SDHC (succinate dehydrogenase complex subunit C); PARTICIPATES IN citric acid cycle pathway; electron transport chain pathway; fumaric aciduria pathway; INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil; amiodarone.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC95158; succinate dehydrogenase complex, subunit C; succinate dehydrogenase complex, subunit C, integral membrane protein; succinate dehydrogenase cytochrome b560 subunit, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21383,544,652 - 83,565,560 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,544,652 - 83,566,253 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,050,394 - 86,071,277 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01387,448,631 - 87,469,514 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01384,680,351 - 84,701,243 (-)NCBIRnor_WKY
Rnor_6.01389,498,047 - 89,518,979 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,498,048 - 89,518,939 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,125,548 - 94,146,440 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,014,569 - 87,035,239 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11387,203,453 - 87,224,123 (-)NCBI
Celera1383,176,204 - 83,197,047 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Succinate dehydrogenase deficiency in human. Briere JJ, etal., Cell Mol Life Sci. 2005 Oct;62(19-20):2317-24.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Genetic variants in genes of tricarboxylic acid cycle key enzymes are associated with prognosis of patients with non-small cell lung cancer. Guo X, etal., Lung Cancer. 2015 Feb;87(2):162-8. doi: 10.1016/j.lungcan.2014.12.005. Epub 2014 Dec 18.
5. Cytochrome b in human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of the components in liver mitochondria and chromosome assignment of the genes for the large (SDHC) and small (SDHD) subunits to 1q21 and 11q23. Hirawake H, etal., Cytogenet Cell Genet 1997;79(1-2):132-8.
6. A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis. Ishii T, etal., Cancer Res 2005 Jan 1;65(1):203-9.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Mutations in SDHC cause autosomal dominant paraganglioma, type 3. Niemann S and Muller U, Nat Genet. 2000 Nov;26(3):268-70.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Assembly of mammalian oxidative phosphorylation complexes I-V and supercomplexes. Signes A and Fernandez-Vizarra E, Essays Biochem. 2018 Jul 20;62(3):255-270. doi: 10.1042/EBC20170098. Print 2018 Jul 20.
17. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:14651853   PMID:15989954   PMID:16120479   PMID:17480203   PMID:18614015   PMID:19808025  


Genomics

Comparative Map Data
Sdhc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21383,544,652 - 83,565,560 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,544,652 - 83,566,253 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,050,394 - 86,071,277 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01387,448,631 - 87,469,514 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01384,680,351 - 84,701,243 (-)NCBIRnor_WKY
Rnor_6.01389,498,047 - 89,518,979 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,498,048 - 89,518,939 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,125,548 - 94,146,440 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,014,569 - 87,035,239 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11387,203,453 - 87,224,123 (-)NCBI
Celera1383,176,204 - 83,197,047 (-)NCBICelera
Cytogenetic Map13q24NCBI
SDHC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,314,381 - 161,375,340 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1161,314,381 - 161,363,206 (+)EnsemblGRCh38hg38GRCh38
GRCh371161,284,171 - 161,345,130 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,550,790 - 159,601,165 (+)NCBINCBI36Build 36hg18NCBI36
Build 341158,097,242 - 158,146,049NCBI
Celera1134,351,304 - 134,401,671 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,641,002 - 132,691,319 (+)NCBIHuRef
CHM1_11162,680,387 - 162,730,796 (+)NCBICHM1_1
T2T-CHM13v2.01160,451,814 - 160,512,783 (+)NCBIT2T-CHM13v2.0
Sdhc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,956,726 - 170,978,209 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,954,734 - 170,978,172 (-)EnsemblGRCm39 Ensembl
GRCm381171,129,157 - 171,150,640 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,127,165 - 171,150,603 (-)EnsemblGRCm38mm10GRCm38
MGSCv371173,059,288 - 173,080,734 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361172,965,840 - 172,987,277 (-)NCBIMGSCv36mm8
Celera1173,578,731 - 173,598,849 (-)NCBICelera
Cytogenetic Map1H3NCBI
Sdhc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546813,049,848 - 13,083,156 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546813,050,359 - 13,083,932 (+)NCBIChiLan1.0ChiLan1.0
SDHC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11140,635,250 - 140,683,390 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,635,685 - 140,682,736 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01136,724,663 - 136,773,038 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SDHC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,162,850 - 21,200,429 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,162,421 - 21,200,333 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3821,237,330 - 21,275,269 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03821,280,197 - 21,318,198 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,275,939 - 21,318,141 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,177,285 - 21,215,371 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03821,583,510 - 21,621,477 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03821,991,569 - 22,029,750 (-)NCBIUU_Cfam_GSD_1.0
Sdhc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,383,971 - 7,428,187 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936903601,355 - 636,092 (+)EnsemblSpeTri2.0
SpeTri2.0NW_004936903592,641 - 636,845 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SDHC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,130,379 - 89,169,118 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,135,410 - 89,169,164 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2496,992,639 - 97,026,545 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SDHC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,613,618 - 2,658,374 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660381,670,467 - 1,715,438 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sdhc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479454,143 - 98,292 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479455,907 - 97,991 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sdhc
61 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:99
Count of miRNA genes:80
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000004228
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat

Markers in Region
AA900320  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,544,834 - 83,545,029 (+)MAPPERmRatBN7.2
Rnor_6.01389,498,230 - 89,498,424NCBIRnor6.0
Rnor_5.01394,125,731 - 94,125,925UniSTSRnor5.0
RGSC_v3.41387,014,752 - 87,014,946UniSTSRGSC3.4
Celera1383,176,387 - 83,176,581UniSTS
RH 3.4 Map13567.6UniSTS
Cytogenetic Map13q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001005534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC082027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000004228   ⟹   ENSRNOP00000004228
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,544,652 - 83,566,253 (-)Ensembl
Rnor_6.0 Ensembl1389,498,048 - 89,518,939 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110173   ⟹   ENSRNOP00000083218
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,544,652 - 83,566,253 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117201   ⟹   ENSRNOP00000077353
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,544,655 - 83,561,127 (-)Ensembl
RefSeq Acc Id: NM_001005534   ⟹   NP_001005534
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21383,544,652 - 83,565,546 (-)NCBI
Rnor_6.01389,498,047 - 89,518,939 (-)NCBI
Rnor_5.01394,125,548 - 94,146,440 (-)NCBI
RGSC_v3.41387,014,569 - 87,035,239 (-)RGD
Celera1383,176,204 - 83,197,047 (-)RGD
Sequence:
RefSeq Acc Id: XM_008769731   ⟹   XP_008767953
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21383,544,652 - 83,565,560 (-)NCBI
Rnor_6.01389,498,047 - 89,518,979 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001005534   ⟸   NM_001005534
- UniProtKB: Q641Z9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008767953   ⟸   XM_008769731
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000004228   ⟸   ENSRNOT00000004228
RefSeq Acc Id: ENSRNOP00000083218   ⟸   ENSRNOT00000110173
RefSeq Acc Id: ENSRNOP00000077353   ⟸   ENSRNOT00000117201

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q641Z9-F1-model_v2 AlphaFold Q641Z9 1-169 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698994
Promoter ID:EPDNEW_R9518
Type:multiple initiation site
Name:Sdhc_1
Description:succinate dehydrogenase complex subunit C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01389,518,958 - 89,519,018EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359454 AgrOrtholog
BioCyc Gene G2FUF-17388 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
  PWY-5690 [TCA cycle II (plants and fungi)] BioCyc
  PWY-7279 [aerobic respiration II (cytochrome c) (yeast)] BioCyc
Ensembl Genes ENSRNOG00000003163 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000004228 ENTREZGENE
  ENSRNOP00000004228.5 UniProtKB/TrEMBL
  ENSRNOP00000077353.1 UniProtKB/TrEMBL
  ENSRNOP00000083218.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004228 ENTREZGENE
  ENSRNOT00000004228.6 UniProtKB/TrEMBL
  ENSRNOT00000110173.1 UniProtKB/TrEMBL
  ENSRNOT00000117201.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1300.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7130052 IMAGE-MGC_LOAD
InterPro SQR/QFR_C/D UniProtKB/TrEMBL
  Succ_DH_cyt_bsu_CS UniProtKB/TrEMBL
  Succ_DH_cytb556 UniProtKB/TrEMBL
  Succ_DH_Fumarate_Rdtase_TM-su UniProtKB/TrEMBL
KEGG Report rno:289217 UniProtKB/TrEMBL
MGC_CLONE MGC:95158 IMAGE-MGC_LOAD
NCBI Gene 289217 ENTREZGENE
PANTHER PTHR10978 UniProtKB/TrEMBL
Pfam Sdh_cyt UniProtKB/TrEMBL
PhenoGen Sdhc PhenoGen
PIRSF SDH_cyt_b560 UniProtKB/TrEMBL
PROSITE SDH_CYT_1 UniProtKB/TrEMBL
  SDH_CYT_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF81343 UniProtKB/TrEMBL
TIGRFAMs succ_dehyd_cytB UniProtKB/TrEMBL
UniProt A0A8I5Y7P2_RAT UniProtKB/TrEMBL
  A0A8I5ZYU8_RAT UniProtKB/TrEMBL
  Q641Z9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-16 Sdhc  succinate dehydrogenase complex subunit C  Sdhc  succinate dehydrogenase complex, subunit C, integral membrane protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Sdhc  succinate dehydrogenase complex, subunit C, integral membrane protein    succinate dehydrogenase complex, subunit C  Name updated 1299863 APPROVED
2005-07-29 Sdhc  succinate dehydrogenase complex, subunit C      Symbol and Name status set to provisional 70820 PROVISIONAL