Arpc5 (actin related protein 2/3 complex, subunit 5) - Rat Genome Database

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Gene: Arpc5 (actin related protein 2/3 complex, subunit 5) Rattus norvegicus
Analyze
Symbol: Arpc5
Name: actin related protein 2/3 complex, subunit 5
RGD ID: 1311791
Description: Predicted to enable actin filament binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in several processes, including actin filament network formation; lamellipodium organization; and orbitofrontal cortex development. Located in endosome and growth cone. Biomarker of congenital hypothyroidism. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human ARPC5 (actin related protein 2/3 complex subunit 5); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; platelet-derived growth factor signaling pathway; Rab family mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: actin-related protein 2/3 complex subunit 5; arp2/3 complex 16 kDa subunit; LOC360854; MGC116419; p16-ARC
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21364,904,504 - 64,913,413 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1364,887,136 - 64,913,410 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1367,506,753 - 67,515,667 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01368,799,611 - 68,808,507 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01366,050,498 - 66,059,442 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01370,174,970 - 70,183,879 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1370,174,936 - 70,183,879 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01375,146,057 - 75,154,966 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41367,755,352 - 67,764,261 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11367,769,431 - 67,778,341 (+)NCBI
Celera1364,811,206 - 64,820,108 (+)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Arp2/3- and cofilin-coordinated actin dynamics is required for insulin-mediated GLUT4 translocation to the surface of muscle cells. Chiu TT, etal., Mol Biol Cell. 2010 Oct 15;21(20):3529-39. doi: 10.1091/mbc.E10-04-0316. Epub 2010 Aug 25.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Arp2/3 complex is important for filopodia formation, growth cone motility, and neuritogenesis in neuronal cells. Korobova F and Svitkina T, Mol Biol Cell. 2008 Apr;19(4):1561-74. Epub 2008 Feb 6.
5. Effects of hypothyroidism on expression of CRMP2B and ARPC5 during development of the rat frontal cortex. Liu CR, etal., Int J Biol Sci. 2013;9(2):209-18. doi: 10.7150/ijbs.5646. Epub 2013 Feb 12.
6. [Proteomic changes in cerebral cortex of neonatal rats with experimental congenital hypothyroidism]. Liu CR, etal., Zhonghua Er Ke Za Zhi. 2011 Mar;49(3):209-13.
7. [Modulation of Jianjining Recipe on differential protein expression in rats with experimental autoimmune myasthenia gravis]. Liu P, etal., Zhong Xi Yi Jie He Xue Bao. 2007 Nov;5(6):642-6.
8. Protein kinase Cdelta and calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2/3 complex and cortactin. Llado A, etal., Mol Biol Cell. 2008 Jan;19(1):17-29. Epub 2007 Oct 24.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma. Moriya Y, etal., J Hum Genet. 2012 Jan;57(1):38-45. doi: 10.1038/jhg.2011.126. Epub 2011 Nov 17.
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
13. GOA pipeline RGD automated data pipeline
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Rear polarization of the microtubule-organizing center in neointimal smooth muscle cells depends on PKCalpha, ARPC5, and RHAMM. Silverman-Gavrila R, etal., Am J Pathol. 2011 Feb;178(2):895-910. doi: 10.1016/j.ajpath.2010.10.001.
Additional References at PubMed
PMID:11741539   PMID:12477932   PMID:15294161   PMID:15489334   PMID:17086175   PMID:19056867   PMID:20458337   PMID:21423176   PMID:22378351   PMID:23106098   PMID:23376485  


Genomics

Comparative Map Data
Arpc5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21364,904,504 - 64,913,413 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1364,887,136 - 64,913,410 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1367,506,753 - 67,515,667 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01368,799,611 - 68,808,507 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01366,050,498 - 66,059,442 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01370,174,970 - 70,183,879 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1370,174,936 - 70,183,879 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01375,146,057 - 75,154,966 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41367,755,352 - 67,764,261 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11367,769,431 - 67,778,341 (+)NCBI
Celera1364,811,206 - 64,820,108 (+)NCBICelera
Cytogenetic Map13q21NCBI
ARPC5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381183,620,846 - 183,635,783 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1183,620,846 - 183,635,783 (-)EnsemblGRCh38hg38GRCh38
GRCh371183,589,981 - 183,604,918 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361181,861,955 - 181,871,608 (-)NCBINCBI36Build 36hg18NCBI36
Build 341180,326,990 - 180,336,642NCBI
Celera1156,706,364 - 156,716,017 (-)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1154,831,187 - 154,840,935 (-)NCBIHuRef
CHM1_11185,018,012 - 185,027,765 (-)NCBICHM1_1
T2T-CHM13v2.01182,980,128 - 182,995,065 (-)NCBIT2T-CHM13v2.0
Arpc5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391152,642,293 - 152,651,331 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1152,642,293 - 152,651,348 (+)EnsemblGRCm39 Ensembl
GRCm381152,766,542 - 152,775,580 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1152,766,542 - 152,775,597 (+)EnsemblGRCm38mm10GRCm38
MGSCv371154,613,672 - 154,622,710 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361154,528,869 - 154,537,793 (+)NCBIMGSCv36mm8
Celera1155,187,898 - 155,196,926 (+)NCBICelera
Cytogenetic Map1G3NCBI
cM Map165.02NCBI
Arpc5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540622,409,239 - 22,418,945 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540622,409,239 - 22,418,950 (-)NCBIChiLan1.0ChiLan1.0
ARPC5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1165,765,277 - 65,774,955 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01159,156,229 - 159,165,898 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11163,313,832 - 163,323,553 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1163,311,111 - 163,323,554 (-)Ensemblpanpan1.1panPan2
ARPC5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1716,976,392 - 16,986,015 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl716,977,555 - 16,985,943 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha716,561,919 - 16,571,550 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0716,708,285 - 16,717,919 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl716,708,289 - 16,717,742 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1716,616,579 - 16,626,207 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0716,725,963 - 16,735,566 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0716,857,010 - 16,866,642 (-)NCBIUU_Cfam_GSD_1.0
Arpc5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934488,420,395 - 88,429,426 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364816,267,091 - 6,278,170 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364816,267,133 - 6,276,173 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARPC5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9124,837,765 - 124,848,105 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19124,839,062 - 124,847,906 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29137,169,358 - 137,178,210 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARPC5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12545,731,049 - 45,740,533 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2545,731,326 - 45,739,508 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605546,947,652 - 46,957,158 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arpc5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462481410,063,092 - 10,073,313 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462481410,063,157 - 10,073,143 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arpc5
29 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:159
Count of miRNA genes:105
Interacting mature miRNAs:133
Transcripts:ENSRNOT00000064068
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135849787273485113Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)135949252277046890Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat

Markers in Region
RH127586  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21364,913,014 - 64,913,229 (+)MAPPERmRatBN7.2
mRatBN7.21221,734,080 - 21,734,293 (-)MAPPERmRatBN7.2
mRatBN7.21364,913,014 - 64,913,227 (-)MAPPERmRatBN7.2
mRatBN7.21221,734,078 - 21,734,293 (+)MAPPERmRatBN7.2
Rnor_6.01370,183,481 - 70,183,695NCBIRnor6.0
Rnor_6.01224,743,520 - 24,743,734NCBIRnor6.0
Rnor_5.01375,154,568 - 75,154,782UniSTSRnor5.0
Rnor_5.01226,743,790 - 26,744,004UniSTSRnor5.0
RGSC_v3.41367,763,863 - 67,764,077UniSTSRGSC3.4
RGSC_v3.41222,798,582 - 22,798,796UniSTSRGSC3.4
Celera1223,495,812 - 23,496,026UniSTS
Celera1364,819,710 - 64,819,924UniSTS
Cytogenetic Map13q21UniSTS
RH139246  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21364,912,993 - 64,913,229 (+)MAPPERmRatBN7.2
mRatBN7.21221,734,080 - 21,734,314 (-)MAPPERmRatBN7.2
mRatBN7.21364,912,993 - 64,913,227 (-)MAPPERmRatBN7.2
mRatBN7.21221,734,078 - 21,734,314 (+)MAPPERmRatBN7.2
Rnor_6.01370,183,460 - 70,183,695NCBIRnor6.0
Rnor_6.01224,743,520 - 24,743,755NCBIRnor6.0
Rnor_5.01375,154,547 - 75,154,782UniSTSRnor5.0
Rnor_5.01226,743,790 - 26,744,025UniSTSRnor5.0
RGSC_v3.41367,763,842 - 67,764,077UniSTSRGSC3.4
RGSC_v3.41222,798,582 - 22,798,817UniSTSRGSC3.4
Celera1223,495,812 - 23,496,047UniSTS
Celera1364,819,689 - 64,819,924UniSTS
Cytogenetic Map13q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 7 9 74 35 41 11 7
Low 1 2 1
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000064068   ⟹   ENSRNOP00000061516
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1364,904,516 - 64,913,410 (+)Ensembl
Rnor_6.0 Ensembl1370,174,936 - 70,183,879 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079861   ⟹   ENSRNOP00000073332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1364,904,470 - 64,912,180 (+)Ensembl
Rnor_6.0 Ensembl1370,175,032 - 70,182,646 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000092562   ⟹   ENSRNOP00000075768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1370,175,136 - 70,182,720 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000092632   ⟹   ENSRNOP00000080708
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1364,887,136 - 64,904,584 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000107757   ⟹   ENSRNOP00000096215
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1364,904,566 - 64,913,404 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000113991   ⟹   ENSRNOP00000082899
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1364,904,566 - 64,913,404 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119326   ⟹   ENSRNOP00000088264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1364,904,486 - 64,913,406 (+)Ensembl
RefSeq Acc Id: NM_001025717   ⟹   NP_001020888
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21364,904,504 - 64,913,413 (+)NCBI
Rnor_6.01370,174,970 - 70,183,879 (+)NCBI
Rnor_5.01375,146,057 - 75,154,966 (+)NCBI
RGSC_v3.41367,755,352 - 67,764,261 (+)RGD
Celera1364,811,206 - 64,820,108 (+)RGD
Sequence:
RefSeq Acc Id: NP_001020888   ⟸   NM_001025717
- UniProtKB: Q4KLF8 (UniProtKB/Swiss-Prot),   A0A8I6AP81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073332   ⟸   ENSRNOT00000079861
RefSeq Acc Id: ENSRNOP00000075768   ⟸   ENSRNOT00000092562
RefSeq Acc Id: ENSRNOP00000061516   ⟸   ENSRNOT00000064068
RefSeq Acc Id: ENSRNOP00000096215   ⟸   ENSRNOT00000107757
RefSeq Acc Id: ENSRNOP00000082899   ⟸   ENSRNOT00000113991
RefSeq Acc Id: ENSRNOP00000080708   ⟸   ENSRNOT00000092632
RefSeq Acc Id: ENSRNOP00000088264   ⟸   ENSRNOT00000119326

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KLF8-F1-model_v2 AlphaFold Q4KLF8 1-151 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698891
Promoter ID:EPDNEW_R9416
Type:initiation region
Name:Arpc5_1
Description:actin related protein 2/3 complex, subunit 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01370,174,964 - 70,175,024EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311791 AgrOrtholog
BioCyc Gene G2FUF-17900 BioCyc
Ensembl Genes ENSRNOG00000028062 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055017932 UniProtKB/Swiss-Prot
  ENSRNOG00060016816 UniProtKB/Swiss-Prot
  ENSRNOG00065026466 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000064068.4 UniProtKB/TrEMBL
  ENSRNOT00000079861.2 UniProtKB/TrEMBL
  ENSRNOT00000092632.2 UniProtKB/TrEMBL
  ENSRNOT00000107757 ENTREZGENE
  ENSRNOT00000107757.1 UniProtKB/TrEMBL
  ENSRNOT00000113991.1 UniProtKB/TrEMBL
  ENSRNOT00000119326.1 UniProtKB/TrEMBL
  ENSRNOT00055030393 UniProtKB/Swiss-Prot
  ENSRNOT00060028908 UniProtKB/Swiss-Prot
  ENSRNOT00065045771 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7445509 IMAGE-MGC_LOAD
InterPro ARPC5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARPC5_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:360854 UniProtKB/Swiss-Prot
MGC_CLONE MGC:116419 IMAGE-MGC_LOAD
NCBI Gene 360854 ENTREZGENE
PANTHER ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12644 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam P16-Arc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Arpc5 PhenoGen
PIRSF p16-ARC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028062 RatGTEx
  ENSRNOG00055017932 RatGTEx
  ENSRNOG00060016816 RatGTEx
  ENSRNOG00065026466 RatGTEx
Superfamily-SCOP SSF69103 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K585_RAT UniProtKB/TrEMBL
  A0A8I5ZRD9_RAT UniProtKB/TrEMBL
  A0A8I6A9N2_RAT UniProtKB/TrEMBL
  A0A8I6AP81 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GA28_RAT UniProtKB/TrEMBL
  A0A8L2QU32_RAT UniProtKB/TrEMBL
  ARPC5_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Arpc5  actin related protein 2/3 complex, subunit 5  Arpc5_predicted  actin related protein 2/3 complex, subunit 5 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Arpc5_predicted  actin related protein 2/3 complex, subunit 5 (predicted)      Symbol and Name status set to approved 70820 APPROVED