Xcl1 (X-C motif chemokine ligand 1) - Rat Genome Database

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Gene: Xcl1 (X-C motif chemokine ligand 1) Rattus norvegicus
Analyze
Symbol: Xcl1
Name: X-C motif chemokine ligand 1
RGD ID: 620452
Description: Predicted to enable CCR chemokine receptor binding activity; chemokine activity; and protein homodimerization activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; positive regulation of leukocyte migration; and regulation of gene expression. Predicted to act upstream of or within chemotaxis; establishment of localization in cell; and release of sequestered calcium ion into cytosol. Predicted to be active in extracellular space. Biomarker of anti-basement membrane glomerulonephritis. Orthologous to several human genes including XCL1 (X-C motif chemokine ligand 1); PARTICIPATES IN chemokine mediated signaling pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: c motif chemokine 1; chemokine (C motif) ligand 1; cytokine SCM-1; Ltn; lymphotactin; Scyc1; small inducible cytokine subfamily C, member 1 (lymphotactin); small-inducible cytokine C1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21377,248,865 - 77,252,308 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1377,248,717 - 77,252,329 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1379,865,290 - 79,868,746 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01381,169,308 - 81,172,764 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01378,411,156 - 78,414,618 (-)NCBIRnor_WKY
Rnor_6.01383,199,402 - 83,202,845 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1383,199,264 - 83,202,864 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01388,079,753 - 88,083,196 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41380,691,195 - 80,694,638 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11380,705,382 - 80,708,826 (-)NCBI
Celera1376,965,267 - 76,968,710 (-)NCBICelera
Cytogenetic Map13q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
antimicrobial humoral immune response mediated by antimicrobial peptide  (ISO)
cell-cell signaling  (ISO)
cellular response to interleukin-1  (IBA)
cellular response to interleukin-4  (IEA,ISO)
cellular response to transforming growth factor beta stimulus  (IEA,ISO)
cellular response to tumor necrosis factor  (IBA)
cellular response to type II interferon  (IBA)
chemokine-mediated signaling pathway  (IBA)
chemotaxis  (ISO)
establishment of localization in cell  (IEA,ISO)
G protein-coupled receptor signaling pathway  (IBA)
immune response  (IEA)
inflammatory response  (IBA)
killing of cells of another organism  (ISO)
lymphocyte chemotaxis  (IBA)
mature natural killer cell chemotaxis  (IEA,ISO)
monocyte chemotaxis  (IBA)
negative regulation of CD4-positive, alpha-beta T cell proliferation  (ISO)
negative regulation of DNA-binding transcription factor activity  (ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of interleukin-2 production  (ISO)
negative regulation of T cell cytokine production  (ISO)
negative regulation of T-helper 1 cell activation  (ISO)
negative regulation of type II interferon production  (ISO)
neutrophil chemotaxis  (IBA)
positive regulation of B cell chemotaxis  (IEA,ISO)
positive regulation of CD4-positive, alpha-beta T cell proliferation  (IEA,ISO)
positive regulation of CD8-positive, alpha-beta T cell proliferation  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IBA)
positive regulation of granzyme A production  (ISO)
positive regulation of granzyme B production  (ISO)
positive regulation of GTPase activity  (IBA)
positive regulation of immunoglobulin production in mucosal tissue  (IEA,ISO)
positive regulation of interleukin-10 production  (ISO)
positive regulation of leukocyte chemotaxis  (ISO)
positive regulation of natural killer cell chemotaxis  (IEA,ISO)
positive regulation of neutrophil chemotaxis  (IEA,ISO)
positive regulation of release of sequestered calcium ion into cytosol  (ISO)
positive regulation of T cell chemotaxis  (IBA,IEA,ISO)
positive regulation of T cell cytokine production  (ISO)
positive regulation of T cell mediated cytotoxicity  (ISO)
positive regulation of T-helper 1 cell cytokine production  (IEA,ISO)
positive regulation of T-helper 2 cell cytokine production  (IEA,ISO)
positive regulation of thymocyte migration  (IEA,ISO)
positive regulation of transforming growth factor beta production  (ISO)
regulation of inflammatory response  (ISO)
release of sequestered calcium ion into cytosol  (IEA,ISO)
response to virus  (ISO)
signal transduction  (IEA)

Cellular Component
extracellular space  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice. Glass WG, etal., J Immunol. 2004 Sep 15;173(6):4030-9. doi: 10.4049/jimmunol.173.6.4030.
3. Lymphotactin: a cytokine that represents a new class of chemokine. Kelner GS, etal., Science 1994 Nov 25;266(5189):1395-9.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Expression of lymphotactin mRNA in experimental crescentic glomerulonephritis. Natori Y, etal., Clin Exp Immunol. 1998 Aug;113(2):265-8.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7602097   PMID:8757601   PMID:9013979   PMID:9029087   PMID:9632725   PMID:9973465   PMID:10518929   PMID:10887101   PMID:11181058   PMID:11889129   PMID:12949249   PMID:14734774  
PMID:18832695   PMID:24155383   PMID:29588250   PMID:31649144  


Genomics

Comparative Map Data
Xcl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21377,248,865 - 77,252,308 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1377,248,717 - 77,252,329 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1379,865,290 - 79,868,746 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01381,169,308 - 81,172,764 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01378,411,156 - 78,414,618 (-)NCBIRnor_WKY
Rnor_6.01383,199,402 - 83,202,845 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1383,199,264 - 83,202,864 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01388,079,753 - 88,083,196 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41380,691,195 - 80,694,638 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11380,705,382 - 80,708,826 (-)NCBI
Celera1376,965,267 - 76,968,710 (-)NCBICelera
Cytogenetic Map13q23NCBI
XCL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381168,576,605 - 168,582,069 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1168,576,605 - 168,582,069 (+)EnsemblGRCh38hg38GRCh38
GRCh371168,545,843 - 168,551,307 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361166,812,480 - 166,817,939 (+)NCBINCBI36Build 36hg18NCBI36
Build 341165,277,513 - 165,282,973NCBI
Celera1141,655,651 - 141,661,108 (+)NCBICelera
Cytogenetic Map1q24.2NCBI
HuRef1139,791,807 - 139,797,411 (+)NCBIHuRef
CHM1_11169,967,701 - 169,973,305 (+)NCBICHM1_1
T2T-CHM13v2.01167,931,697 - 167,937,161 (+)NCBIT2T-CHM13v2.0
Xcl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391164,759,213 - 164,763,091 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1164,759,213 - 164,763,096 (-)EnsemblGRCm39 Ensembl
GRCm381164,931,644 - 164,935,522 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1164,931,644 - 164,935,527 (-)EnsemblGRCm38mm10GRCm38
MGSCv371166,861,779 - 166,865,641 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361166,768,323 - 166,772,185 (-)NCBIMGSCv36mm8
Celera1167,368,241 - 167,372,103 (-)NCBICelera
Cytogenetic Map1H2.2NCBI
cM Map172.26NCBI
Xcl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554628,594,416 - 8,598,101 (-)NCBIChiLan1.0ChiLan1.0
XCL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11147,563,331 - 147,790,587 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1147,785,654 - 147,790,587 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01143,837,578 - 144,068,261 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LOC490356
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1729,986,433 - 29,991,096 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha729,518,512 - 29,708,129 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0729,804,708 - 29,995,081 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1729,637,969 - 29,827,991 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0729,673,524 - 29,863,628 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0729,911,837 - 30,102,031 (-)NCBIUU_Cfam_GSD_1.0
LOC101970885
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934499,978,802 - 99,991,355 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648117,825,714 - 17,828,955 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XCL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl482,432,204 - 82,436,180 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1482,432,845 - 82,436,150 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2490,116,396 - 90,119,701 (-)NCBISscrofa10.2Sscrofa10.2susScr3
XCL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366605562,128,985 - 62,134,506 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Position Markers
AI236158  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21377,248,803 - 77,248,924 (+)MAPPERmRatBN7.2
Rnor_6.01383,199,341 - 83,199,461NCBIRnor6.0
Rnor_5.01388,079,692 - 88,079,812UniSTSRnor5.0
RGSC_v3.41380,691,134 - 80,691,254UniSTSRGSC3.4
Celera1376,965,206 - 76,965,326UniSTS
RH 3.4 Map13485.8UniSTS
Cytogenetic Map13q23UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
4889861Pur29Proteinuria QTL 2913.80.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)137402391880753406Rat
8655959Pur32Proteinuria QTL 328.4total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:19
Count of miRNA genes:15
Interacting mature miRNAs:18
Transcripts:ENSRNOT00000003976
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 6 14 2
Low 3 14 35 29 5 29 1 2 8 22 18 11 1
Below cutoff 18 16 12 12 7 7 33 13 18 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003976   ⟹   ENSRNOP00000003976
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1377,248,717 - 77,252,329 (-)Ensembl
Rnor_6.0 Ensembl1383,199,264 - 83,202,864 (-)Ensembl
RefSeq Acc Id: NM_134361   ⟹   NP_599188
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21377,248,865 - 77,252,308 (-)NCBI
Rnor_6.01383,199,402 - 83,202,845 (-)NCBI
Rnor_5.01388,079,753 - 88,083,196 (-)NCBI
RGSC_v3.41380,691,195 - 80,694,638 (-)RGD
Celera1376,965,267 - 76,968,710 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_599188 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA69478 (Get FASTA)   NCBI Sequence Viewer  
  EDM09342 (Get FASTA)   NCBI Sequence Viewer  
  P51672 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_599188   ⟸   NM_134361
- Peptide Label: precursor
- UniProtKB: P51672 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000003976   ⟸   ENSRNOT00000003976
Protein Domains
SCY

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P51672-F1-model_v2 AlphaFold P51672 1-114 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620452 AgrOrtholog
BioCyc Gene G2FUF-17583 BioCyc
Ensembl Genes ENSRNOG00000002964 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000003976 ENTREZGENE
  ENSRNOP00000003976.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003976 ENTREZGENE
  ENSRNOT00000003976.4 UniProtKB/TrEMBL
InterPro Chemokine_b/g/d UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_XCL1/XCL2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171371 UniProtKB/Swiss-Prot
NCBI Gene 171371 ENTREZGENE
PANTHER PTHR12015 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12015:SF101 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Xcl1 PhenoGen
PRINTS LYMPHOTACTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SCY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A4D6YKM5_RAT UniProtKB/TrEMBL
  A0A4D6YMT2_RAT UniProtKB/TrEMBL
  A0A4D6YMU3_RAT UniProtKB/TrEMBL
  A0A4D6YMV4_RAT UniProtKB/TrEMBL
  A0A4D6YNR9_RAT UniProtKB/TrEMBL
  A0A4D6YW90_RAT UniProtKB/TrEMBL
  G3V6D4_RAT UniProtKB/TrEMBL
  P51672 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-08 Xcl1  X-C motif chemokine ligand 1  Xcl1  chemokine (C motif) ligand 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Xcl1  chemokine (C motif) ligand 1    small inducible cytokine subfamily C, member 1 (lymphotactin)  Name updated 1299863 APPROVED
2004-09-10 Xcl1  small inducible cytokine subfamily C, member 1 (lymphotactin)  Scyc1    Symbol and Name updated 1299863 APPROVED
2002-08-07 Scyc1  small inducible cytokine subfamily C, member 1 (lymphotactin)      Symbol and Name status set to provisional 70820 PROVISIONAL