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Gene: Hsd17b7 (hydroxysteroid (17-beta) dehydrogenase 7) Rattus norvegicus
Symbol: Hsd17b7
Name: hydroxysteroid (17-beta) dehydrogenase 7
RGD ID: 2837
Description: Exhibits estradiol 17-beta-dehydrogenase activity and prolactin receptor binding activity. Involved in several processes, including estrogen biosynthetic process; response to estradiol; and response to prolactin. Localizes to membrane. Biomarker of polycystic ovary syndrome. Orthologous to human HSD17B7 (hydroxysteroid 17-beta dehydrogenase 7); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 17-beta-HSD 7; 17-beta-hydroxysteroid dehydrogenase 7; 3-keto-steroid reductase; 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7; dihydrotestosterone oxidoreductase; estradiol 17-beta-dehydrogenase 7; hydroxysteroid 17-beta dehydrogenase 7; hydroxysteroid dehydrogenase 17 beta, type 7; PRAP; PRL receptor-associated protein
Homo sapiens (human) : HSD17B7 (hydroxysteroid 17-beta dehydrogenase 7)  HGNC  Alliance
Mus musculus (house mouse) : Hsd17b7 (hydroxysteroid (17-beta) dehydrogenase 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hsd17b7 (hydroxysteroid 17-beta dehydrogenase 7)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100985156 (3-keto-steroid reductase)
Canis lupus familiaris (dog) : HSD17B7 (hydroxysteroid 17-beta dehydrogenase 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hsd17b7 (hydroxysteroid 17-beta dehydrogenase 7)
Sus scrofa (pig) : HSD17B7 (hydroxysteroid 17-beta dehydrogenase 7)
Chlorocebus sabaeus (African green monkey) : HSD17B7 (hydroxysteroid 17-beta dehydrogenase 7)
Heterocephalus glaber (naked mole-rat) : Hsd17b7 (hydroxysteroid 17-beta dehydrogenase 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01388,288,116 - 88,308,019 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1388,288,046 - 88,307,988 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01392,914,581 - 92,934,289 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41385,776,077 - 85,792,977 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11385,790,264 - 85,807,165 (-)NCBI
Celera1381,835,166 - 81,852,028 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Hsd17b7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2837
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.