HSD17B7 (hydroxysteroid 17-beta dehydrogenase 7)

Gene: HSD17B7 (hydroxysteroid 17-beta dehydrogenase 7) Sus scrofa

Analyze

Symbol:

HSD17B7

Name:

hydroxysteroid 17-beta dehydrogenase 7

RGD ID:

14161295

Description:

ENCODES a protein that exhibits prolactin receptor binding (ortholog); INVOLVED IN brain development (ortholog); cell differentiation (ortholog); cholesterol biosynthetic process (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); parathyroid carcinoma (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH deoxynivalenol

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

17-beta-hydroxysteroid dehydrogenase 7; 3-keto-steroid reductase; 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	87,720,118 - 87,742,992 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	87,720,747 - 87,743,037 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	95,571,675 - 95,593,948 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

parathyroid carcinoma (ISO)

polycystic ovary syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

deoxynivalenol (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

androgen metabolic process (IEA)

brain development (ISO)

cell differentiation (ISO)

cholesterol biosynthetic process (IEA,ISO)

embryonic organ development (ISO)

embryonic skeletal system development (ISO)

estrogen biosynthetic process (IEA)

hippocampus development (ISO)

maternal process involved in female pregnancy (ISO)

nervous system development (ISO)

response to estradiol (ISO)

response to organic cyclic compound (ISO)

response to prolactin (ISO)

response to xenobiotic stimulus (ISO)

steroid biosynthetic process (IEA)

Cellular Component

endoplasmic reticulum (ISO)

endoplasmic reticulum membrane (IEA)

membrane (IEA)

Molecular Function

3-keto sterol reductase activity (IEA)

5alpha-androstane-3beta,17beta-diol dehydrogenase activity (IEA)

estradiol 17-beta-dehydrogenase [NAD(P)] activity (IEA)

oxidoreductase activity (IEA)

prolactin receptor binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

alendronate pharmacodynamics pathway (ISO)

cholesterol biosynthetic pathway (ISO)

cholesterol ester storage disease pathway (ISO)

congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway (ISO)

desmosterolosis pathway (ISO)

hypercholesterolemia pathway (ISO)

ibandronate pharmacodynamics pathway (ISO)

mevalonic aciduria pathway (ISO)

nitrogenous bisphosphonate pharmacodynamics pathway (ISO)

pamidronate pharmacodynamics pathway (ISO)

risedronate pharmacodynamics pathway (ISO)

Smith-Lemli-Opitz Syndrome pathway (ISO)

statin pharmacodynamics pathway (ISO)

Wolman disease pathway (ISO)

X-linked dominant chondrodysplasia punctata 2 pathway (ISO)

zoledronate pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:22301074	PMID:22405929	PMID:23300627	PMID:30032202

Genomics

Comparative Map Data

HSD17B7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	87,720,118 - 87,742,992 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	87,720,747 - 87,743,037 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	95,571,675 - 95,593,948 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HSD17B7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	162,790,702 - 162,812,823 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	162,790,702 - 162,812,823 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	162,760,492 - 162,782,613 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	161,027,120 - 161,049,232 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	159,492,153 - 159,514,265	NCBI
Celera	1	135,864,558 - 135,886,965 (+)	NCBI		Celera
Cytogenetic Map	1	q23.3	NCBI
HuRef	1	134,005,589 - 134,028,003 (+)	NCBI		HuRef
CHM1_1	1	164,183,061 - 164,205,170 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	162,134,938 - 162,157,387 (+)	NCBI		T2T-CHM13v2.0

Hsd17b7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	169,777,109 - 169,796,757 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	169,777,104 - 169,796,810 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	169,949,535 - 169,969,242 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	169,949,535 - 169,969,241 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	171,879,668 - 171,899,336 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	171,786,212 - 171,805,880 (-)	NCBI		MGSCv36	mm8
Celera	1	172,391,590 - 172,411,249 (-)	NCBI		Celera
Cytogenetic Map	1	H3	NCBI
cM Map	1	76.84	NCBI

Hsd17b7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	84,702,875 - 84,722,810 (-)	NCBI		GRCr8
mRatBN7.2	13	82,170,079 - 82,190,018 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	82,173,179 - 82,190,017 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	84,799,751 - 84,816,641 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	86,093,813 - 86,110,564 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	83,324,993 - 83,341,883 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	88,288,116 - 88,308,019 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	88,288,046 - 88,307,988 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	92,914,581 - 92,934,289 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	85,776,077 - 85,792,977 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	85,790,264 - 85,807,165 (-)	NCBI
Celera	13	81,835,166 - 81,852,028 (-)	NCBI		Celera
Cytogenetic Map	13	q24	NCBI

Hsd17b7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955462	13,557,292 - 13,574,593 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955462	13,555,488 - 13,574,506 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC100985156
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	51,005,870 - 51,028,676 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	51,011,219 - 51,034,004 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	38,424,713 - 38,447,193 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	142,001,063 - 142,017,150 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	142,001,162 - 142,022,865 (+)	Ensembl	panpan1.1		panPan2

HSD17B7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	19,975,935 - 19,999,077 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	19,977,086 - 19,999,010 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	20,031,119 - 20,054,229 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	20,059,511 - 20,082,663 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	20,058,310 - 20,082,624 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	20,034,574 - 20,057,608 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	20,386,347 - 20,409,416 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	20,677,507 - 20,700,653 (-)	NCBI		UU_Cfam_GSD_1.0

Hsd17b7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	8,635,691 - 8,660,282 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936831	951,562 - 977,208 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936831	951,603 - 976,159 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HSD17B7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	1,271,259 - 1,289,232 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	1,273,052 - 1,288,930 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	290,535 - 308,235 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hsd17b7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624826	1,260,223 - 1,283,741 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624826	1,260,133 - 1,287,565 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in HSD17B7
392 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium	6	2		5		10		1	1
Low	4	2	3		2	13	2	2	2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001185137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005655375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005655376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005655377	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001303420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB529536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AEMK02000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK235959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK391692	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CT990609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU582912	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM208213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01033604	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000006945 ⟹ ENSSSCP00000006756

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	4	87,720,118 - 87,742,992 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000057160 ⟹ ENSSSCP00000041234

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	4	87,720,754 - 87,742,986 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000085209 ⟹ ENSSSCP00000062902

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	4	87,720,118 - 87,741,708 (-)	Ensembl

RefSeq Acc Id:

NM_001185137 ⟹ NP_001172066

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	87,720,964 - 87,742,915 (-)	NCBI

Sequence:

show sequence

ATGCGGAAGGTGGTACTGATCACCGGGGCTAGCAGTGGCGTTGGCCTAGCCCTCTTCAGGCGGT
TGCTGAAGGAAGATGATGGACTTCACCTGTGCTTGGCCTGCAGGAATTTGAGTAAAGCGGAGGC
TGTCCGTGCTTCTCTGCTTGCCTCCCACCCTGACGCCGAGGTCACCACTGTGCAAGTGGATGTC
AGCAGCTTGTCATCGGTGTTCCGGGCCTCCAAAGAGCTCAAGGAAAGGTTTCAGAGATTAGACT
ATGTATATCTGAATGCTGGGATCATGCCTAATCCACAGCTAAATATAAAAGCACTTTTCTGTAG
CCTGTTTTCAAGAAAAGCGATTCATGTGTTCTCCACAGCTGAAGGACTGTTGACCCAGAATGAC
AAGATCACTGCTGATGGGCTCCAGGAGGTGTTTGAAACCAATATCTTTGGCCACTTTATCCTGA
TTCGGGAACTGGAATCTCTTCTGTGCCACAGTGACAGTCCATCTCAGCTCATTTGGACATCATC
CCGCAATGCAAGGAAATCTAATTTCAGCCTTGAGGACATCCAGCACAGCAAAGGCCAGGAGCCC
TACAGCTCTTCCAATTATGCTATAGACTTTGTGAGTGTGGCTTTGAACCGGAAATTTAACCAGC
GGGGTTTATATTCCAGTGTGGTGTGTCCAGGGACCATGTTGACCAACTTGACGTATGGAATTTT
ATCTCCTTTTATGTGGATGCTGATCATGCCAATGATATGGCTGTTGCGCTTTTTTGCAAATGCT
TTCACTTTGACACCGTACAATGGAACAGAAGCACTGGTCTGGCTTTTCCACCAAAAGCCTGAGT
CTCTCAATCCTCTGGTGAAATATCTGAGTGCCACCACTGGTTTTGGCAGCAATTACGTAACGTC
CAAAAAGATGGACCTAGATGAAGACACTGCTGAAAAATGTTACCAAAACTTACTGGAACTGGAA
AAGCATGTCAGGGTTACCATTAAAAAAACTGATAACCAGAGCTGA

hide sequence

RefSeq Acc Id:

XM_005655375 ⟹ XP_005655432

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	87,720,747 - 87,743,023 (-)	NCBI

Sequence:

show sequence

CTGATTGAAGGGCTGGGGGCGTGGCCTGGGCGGGGCGTGGGTCAAAAGGGCTTCCGAGAAGCTT
TGCCGGATGCCTGCTTGGCTTGCGCTGCATTGGTGTGTGAGACGATGCGGAAGGTGGTACTGAT
CACCGGGGCTAGCAGGAATTTGAGTAAAGCGGAGGCTGTCCGTGCTTCTCTGCTTGCCTCCCAC
CCTGACGCCGAGGTCACCACTGTGCAAGTGGATGTCAGCAGCTTGTCATCGGTGTTCCGGGCCT
CCAAAGAGCTCAAGGAAAGGTTTCAGAGATTAGACTATGTATATCTGAATGCTGGGATCATGCC
TAATCCACAGCTAAATATAAAAGCACTTTTCTGTAGCCTGTTTTCAAGAAAAGCGATTCATGTG
TTCTCCACAGCTGAAGGACTGTTGACCCAGAATGACAAGATCACTGCTGATGGGCTCCAGGAGG
TGTTTGAAACCAATATCTTTGGCCACTTTATCCTGATTCGGGAACTGGAATCTCTTCTGTGCCA
CAGTGACAGTCCATCTCAGCTCATTTGGACATCATCCCGCAATGCAAGGAAATCTAATTTCAGC
CTTGAGGACATCCAGCACAGCAAAGGCCAGGAGCCCTACAGCTCTTCCAAATATGCTATAGACC
TTCTGAGTGTGGCTTTGAACCGGAAATTTAACCAGCGGGGTTTATATTCCAGTGTGGTGTGTCC
AGGGACCATGTTGACCAACTTGACATATGGAATTTTATCTCCTTTTATGTGGATGCTGATCATG
CCAATGATATGGCTGTTGCGCTTTTTTGCAAATGCTTTCACTTTGACACCGTACAATGGAACAG
AAGCACTGGTCTGGCTTTTCCACCAAAAGCCTGAGTCTCTCAATCCTCTGGTGAAATATCTGAG
TGCCACCACTGGTTTTGGCAGCAATTACGTAACGTCCAAAAAGATGGACCTAGATGAAGACACT
GCTGAAAAATGTTACCAAAACTTACTGGAACTGGAAAAGCATGTCAGGGTTACCATTAAAAAAA
CTGATAACCAGAGCTGATGATGAGGCTCTCTGAAACCTTTCATACCATCTGTGGATTCTGGAGC
ATGTCGGTTTCTACTGAGGGGGATGATACGCATTTGTGGTAAATTATGAACTCTGATAGTCTCT
TCCTTCATTTCAGAATCACCTCTCGGGCTGTGCCTGAGGAAAAGATTGATAAAATGTCAGTTAT
TCTTAAGAATGGTGTCACATTAAAATTGAGTCACCCAATCAA

hide sequence

RefSeq Acc Id:

XM_005655376 ⟹ XP_005655433

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	87,720,747 - 87,743,037 (-)	NCBI

Sequence:

show sequence

GGCCTCGTCAGTCCCTGATTGAAGGGCTGGGGGCGTGGCCTGGGCGGGGCGTGGGTCAAAAGGG
CTTCCGAGAAGCTTTGCCGGATGCCTGCTTGGCTTGCGCTGCATTGGTGTGTGAGACGATGCGG
AAGGTGGTACTGATCACCGGGGCTAGCAGTGGCGTTGGCCTAGCCCTCTGCAGGCGGTTGCTGA
AGGAAGACGATGGACTTCACCTGTGCTTGGCCTGCAGGAATTTGAGTAAAGCGGAGGCTGTCCG
TGCTTCTCTGCTTGCCTCCCACCCTGACGCCGAGGTCACCACTGTGCAAGTGGATGTCAGCAGC
TTGTCATCGGTGTTCCGGGCCTCCAAAGAGCTCAAGGAAAGAAAAGCGATTCATGTGTTCTCCA
CAGCTGAAGGACTGTTGACCCAGAATGACAAGATCACTGCTGATGGGCTCCAGGAGGTGTTTGA
AACCAATATCTTTGGCCACTTTATCCTGATTCGGGAACTGGAATCTCTTCTGTGCCACAGTGAC
AGTCCATCTCAGCTCATTTGGACATCATCCCGCAATGCAAGGAAATCTAATTTCAGCCTTGAGG
ACATCCAGCACAGCAAAGGCCAGGAGCCCTACAGCTCTTCCAAATATGCTATAGACCTTCTGAG
TGTGGCTTTGAACCGGAAATTTAACCAGCGGGGTTTATATTCCAGTGTGGTGTGTCCAGGGACC
ATGTTGACCAACTTGACATATGGAATTTTATCTCCTTTTATGTGGATGCTGATCATGCCAATGA
TATGGCTGTTGCGCTTTTTTGCAAATGCTTTCACTTTGACACCGTACAATGGAACAGAAGCACT
GGTCTGGCTTTTCCACCAAAAGCCTGAGTCTCTCAATCCTCTGGTGAAATATCTGAGTGCCACC
ACTGGTTTTGGCAGCAATTACGTAACGTCCAAAAAGATGGACCTAGATGAAGACACTGCTGAAA
AATGTTACCAAAACTTACTGGAACTGGAAAAGCATGTCAGGGTTACCATTAAAAAAACTGATAA
CCAGAGCTGATGATGAGGCTCTCTGAAACCTTTCATACCATCTGTGGATTCTGGAGCATGTCGG
TTTCTACTGAGGGGGATGATACGCATTTGTGGTAAATTATGAACTCTGATAGTCTCTTCCTTCA
TTTCAGAATCACCTCTCGGGCTGTGCCTGAGGAAAAGATTGATAAAATGTCAGTTATTCTTAAG
AATGGTGTCACATTAAAATTGAGTCACCCAATCAA

hide sequence

RefSeq Acc Id:

XM_005655377 ⟹ XP_005655434

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	87,720,747 - 87,743,037 (-)	NCBI

Sequence:

show sequence

GGCCTCGTCAGTCCCTGATTGAAGGGCTGGGGGCGTGGCCTGGGCGGGGCGTGGGTCAAAAGGG
CTTCCGAGAAGCTTTGCCGGATGCCTGCTTGGCTTGCGCTGCATTGGTGTGTGAGACGATGCGG
AAGGTGGTACTGATCACCGGGGCTAGCAGTGGCGTTGGCCTAGCCCTCTGCAGGCGGTTGCTGA
AGGAAGACGATGGACTTCACCTGTGCTTGGCCTGCAGGAATTTGAGTAAAGCGGAGGCTGTCCG
TGCTTCTCTGCTTGCCTCCCACCCTGACGCCGAGGTCACCACTGTGCAAGTGGATGTCAGCAGC
TTGTCATCGGTGTTCCGGGCCTCCAAAGAGCTCAAGGAAAGGTTTCAGAGATTAGACTATGTAT
ATCTGAATGCTGGGATCATGCCTAATCCACAGCTAAATATAAAAGCACTTTTCTGTAGCCTGTT
TTCAAGAAAAGCGATTCATGTGTTCTCCACAGCTGAAGGACTGTTGACCCAGAATGACAAGATC
ACTGCTGATGGGCTCCAGGAGGTGTTTGAAACCAATATCTTTGGCCACTTTATCCTGGGTTTAT
ATTCCAGTGTGGTGTGTCCAGGGACCATGTTGACCAACTTGACATATGGAATTTTATCTCCTTT
TATGTGGATGCTGATCATGCCAATGATATGGCTGTTGCGCTTTTTTGCAAATGCTTTCACTTTG
ACACCGTACAATGGAACAGAAGCACTGGTCTGGCTTTTCCACCAAAAGCCTGAGTCTCTCAATC
CTCTGGTGAAATATCTGAGTGCCACCACTGGTTTTGGCAGCAATTACGTAACGTCCAAAAAGAT
GGACCTAGATGAAGACACTGCTGAAAAATGTTACCAAAACTTACTGGAACTGGAAAAGCATGTC
AGGGTTACCATTAAAAAAACTGATAACCAGAGCTGATGATGAGGCTCTCTGAAACCTTTCATAC
CATCTGTGGATTCTGGAGCATGTCGGTTTCTACTGAGGGGGATGATACGCATTTGTGGTAAATT
ATGAACTCTGATAGTCTCTTCCTTCATTTCAGAATCACCTCTCGGGCTGTGCCTGAGGAAAAGA
TTGATAAAATGTCAGTTATTCTTAAGAATGGTGTCACATTAAAATTGAGTCACCCAATCAA

hide sequence

RefSeq Acc Id:

XR_001303420

Type:

NON-CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	87,732,944 - 87,743,037 (-)	NCBI

Sequence:

show sequence

GGCCTCGTCAGTCCCTGATTGAAGGGCTGGGGGCGTGGCCTGGGCGGGGCGTGGGTCAAAAGGG
CTTCCGAGAAGCTTTGCCGGATGCCTGCTTGGCTTGCGCTGCATTGGTGTGTGAGACGATGCGG
AAGGTGGTACTGATCACCGGGGCTAGCAGTGGCGTTGGCCTAGCCCTCTGCAGGCGGTTGCTGA
AGGAAGACGATGGACTTCACCTGTGCTTGGCCTGCAGGAATTTGAGTAAAGCGGAGGCTGTCCG
TGCTTCTCTGCTTGCCTCCCACCCTGACGCCGAGGTCACCACTGTGCAAGTGGATGTCAGCAGC
TTGTCATCGGTGTTCCGGGCCTCCAAAGAGCTCAAGGAAAGGTTTCAGAGATTAGACTATGTAT
ATCTGAATGCTGGGATCATGCCTAATCCACAGCTAAATATAAAAGCACTTTTCTGTAGCCTGTT
TTCAAGAAAAGCGATTCATGTGTTCTCCACAGCTGAAGGACTGTTGACCCAGAATGACAAGATC
ACTGCTGATGGGCTCCAGGAGGTGTTTGAAACCAATATCTTTGGCCACTTTATCCTGCTTTAGA
GAGCAGAGAGAAAGTAAGAAATGAACACTCAAATGCCATCAGAAACAATGTACGGAACTGCACC
AGTGTTGTTCTAAATGGTCTTTGAAACTGGGCTTGGTATCAGATAGGATGGGGGAATAATAGAT
TCGGGAACTGGAATCTCTTCTGTGCCACAGTGACAGTCCATCTCAGCTCATTTGGACATCATCC
CGCAATGCAAGGAAATCTAATTTCAGCCTTGAGGACATCCAGC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001172066	(Get FASTA)	NCBI Sequence Viewer
	XP_005655432	(Get FASTA)	NCBI Sequence Viewer
	XP_005655433	(Get FASTA)	NCBI Sequence Viewer
	XP_005655434	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAI47716	(Get FASTA)	NCBI Sequence Viewer
	CAR63891	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000006756
	ENSSSCP00000006756.2
	ENSSSCP00000041234
	ENSSSCP00000041234.1
	ENSSSCP00000062902.1
	ENSSSCP00005020657.1
	ENSSSCP00005020672.1
	ENSSSCP00005020688.1
	ENSSSCP00015042400.1
	ENSSSCP00015042423.1
	ENSSSCP00015042453.1
	ENSSSCP00025024784.1
	ENSSSCP00025024853.1
	ENSSSCP00025024913.1
	ENSSSCP00030021593.1
	ENSSSCP00030021627.1
	ENSSSCP00030021644.1
	ENSSSCP00030021648.1
	ENSSSCP00035043477.1
	ENSSSCP00035043489.1
	ENSSSCP00035043510.1
	ENSSSCP00035043541.1
	ENSSSCP00040040446.1
	ENSSSCP00040040524.1
	ENSSSCP00040040571.1
	ENSSSCP00045036282.1
	ENSSSCP00045036390.1
	ENSSSCP00045036461.1
	ENSSSCP00045036512.1
	ENSSSCP00050037611.1
	ENSSSCP00050037614.1
	ENSSSCP00050037619.1
	ENSSSCP00050037620.1
	ENSSSCP00055019591.1
	ENSSSCP00055019639.1
	ENSSSCP00055019669.1
	ENSSSCP00060001900.1
	ENSSSCP00060001902.1
	ENSSSCP00060001903.1
	ENSSSCP00065018117.1
	ENSSSCP00065018119.1
	ENSSSCP00065018122.1
	ENSSSCP00070042062.1
	ENSSSCP00070042064.1

RefSeq Acc Id:	XP_005655433 ⟸ XM_005655376
- Peptide Label:	isoform X2
- UniProtKB:	A0A287ABG3 (UniProtKB/TrEMBL), A0A8D0JAG7 (UniProtKB/TrEMBL), A0A480HNU3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRKVVLITGASSGVGLALCRRLLKEDDGLHLCLACRNLSKAEAVRASLLASHPDAEVTTVQVDV SSLSSVFRASKELKERKAIHVFSTAEGLLTQNDKITADGLQEVFETNIFGHFILIRELESLLCH SDSPSQLIWTSSRNARKSNFSLEDIQHSKGQEPYSSSKYAIDLLSVALNRKFNQRGLYSSVVCP GTMLTNLTYGILSPFMWMLIMPMIWLLRFFANAFTLTPYNGTEALVWLFHQKPESLNPLVKYLS ATTGFGSNYVTSKKMDLDEDTAEKCYQNLLELEKHVRVTIKKTDNQS hide sequence

RefSeq Acc Id:	XP_005655434 ⟸ XM_005655377
- Peptide Label:	isoform X3
- UniProtKB:	A0A8D0S8P5 (UniProtKB/TrEMBL), F1S213 (UniProtKB/TrEMBL), A0A8D1D4I7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRKVVLITGASSGVGLALCRRLLKEDDGLHLCLACRNLSKAEAVRASLLASHPDAEVTTVQVDV SSLSSVFRASKELKERFQRLDYVYLNAGIMPNPQLNIKALFCSLFSRKAIHVFSTAEGLLTQND KITADGLQEVFETNIFGHFILGLYSSVVCPGTMLTNLTYGILSPFMWMLIMPMIWLLRFFANAF TLTPYNGTEALVWLFHQKPESLNPLVKYLSATTGFGSNYVTSKKMDLDEDTAEKCYQNLLELEK HVRVTIKKTDNQS hide sequence

RefSeq Acc Id:	XP_005655432 ⟸ XM_005655375
- Peptide Label:	isoform X1
- UniProtKB:	A0A480TP00 (UniProtKB/TrEMBL), A0A8D0S8P5 (UniProtKB/TrEMBL), F1S213 (UniProtKB/TrEMBL), A0A8D1D4I7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRKVVLITGASRNLSKAEAVRASLLASHPDAEVTTVQVDVSSLSSVFRASKELKERFQRLDYVY LNAGIMPNPQLNIKALFCSLFSRKAIHVFSTAEGLLTQNDKITADGLQEVFETNIFGHFILIRE LESLLCHSDSPSQLIWTSSRNARKSNFSLEDIQHSKGQEPYSSSKYAIDLLSVALNRKFNQRGL YSSVVCPGTMLTNLTYGILSPFMWMLIMPMIWLLRFFANAFTLTPYNGTEALVWLFHQKPESLN PLVKYLSATTGFGSNYVTSKKMDLDEDTAEKCYQNLLELEKHVRVTIKKTDNQS hide sequence

RefSeq Acc Id:

NP_001172066 ⟸ NM_001185137

- UniProtKB:

D0G6Y2 (UniProtKB/TrEMBL), A0A8D0S8P5 (UniProtKB/TrEMBL), F1S213 (UniProtKB/TrEMBL), A0A8D1D4I7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRKVVLITGASSGVGLALFRRLLKEDDGLHLCLACRNLSKAEAVRASLLASHPDAEVTTVQVDV
SSLSSVFRASKELKERFQRLDYVYLNAGIMPNPQLNIKALFCSLFSRKAIHVFSTAEGLLTQND
KITADGLQEVFETNIFGHFILIRELESLLCHSDSPSQLIWTSSRNARKSNFSLEDIQHSKGQEP
YSSSNYAIDFVSVALNRKFNQRGLYSSVVCPGTMLTNLTYGILSPFMWMLIMPMIWLLRFFANA
FTLTPYNGTEALVWLFHQKPESLNPLVKYLSATTGFGSNYVTSKKMDLDEDTAEKCYQNLLELE
KHVRVTIKKTDNQS

hide sequence

RefSeq Acc Id:

ENSSSCP00000006756 ⟸ ENSSSCT00000006945

RefSeq Acc Id:

ENSSSCP00000062902 ⟸ ENSSSCT00000085209

RefSeq Acc Id:

ENSSSCP00000041234 ⟸ ENSSSCT00000057160

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000006337	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00005021235	UniProtKB/TrEMBL
	ENSSSCG00015075624	UniProtKB/TrEMBL
	ENSSSCG00025043096	UniProtKB/TrEMBL
	ENSSSCG00030034582	UniProtKB/TrEMBL
	ENSSSCG00035075073	UniProtKB/TrEMBL
	ENSSSCG00040066935	UniProtKB/TrEMBL
	ENSSSCG00045030473	UniProtKB/TrEMBL
	ENSSSCG00050064416	UniProtKB/TrEMBL
	ENSSSCG00055012465	UniProtKB/TrEMBL
	ENSSSCG00060004510	UniProtKB/TrEMBL
	ENSSSCG00065031530	UniProtKB/TrEMBL
	ENSSSCG00070024932	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000006945	ENTREZGENE
	ENSSSCT00000006945.4	UniProtKB/TrEMBL
	ENSSSCT00000057160	ENTREZGENE
	ENSSSCT00000057160.1	UniProtKB/TrEMBL
	ENSSSCT00000085209.1	UniProtKB/TrEMBL
	ENSSSCT00005033834.1	UniProtKB/TrEMBL
	ENSSSCT00005033859.1	UniProtKB/TrEMBL
	ENSSSCT00005033890.1	UniProtKB/TrEMBL
	ENSSSCT00015102240.1	UniProtKB/TrEMBL
	ENSSSCT00015102279.1	UniProtKB/TrEMBL
	ENSSSCT00015102324.1	UniProtKB/TrEMBL
	ENSSSCT00025058513.1	UniProtKB/TrEMBL
	ENSSSCT00025058680.1	UniProtKB/TrEMBL
	ENSSSCT00025058787.1	UniProtKB/TrEMBL
	ENSSSCT00030047915.1	UniProtKB/TrEMBL
	ENSSSCT00030047972.1	UniProtKB/TrEMBL
	ENSSSCT00030048001.1	UniProtKB/TrEMBL
	ENSSSCT00030048009.1	UniProtKB/TrEMBL
	ENSSSCT00035102015.1	UniProtKB/TrEMBL
	ENSSSCT00035102039.1	UniProtKB/TrEMBL
	ENSSSCT00035102077.1	UniProtKB/TrEMBL
	ENSSSCT00035102138.1	UniProtKB/TrEMBL
	ENSSSCT00040091686.1	UniProtKB/TrEMBL
	ENSSSCT00040091848.1	UniProtKB/TrEMBL
	ENSSSCT00040091944.1	UniProtKB/TrEMBL
	ENSSSCT00045052147.1	UniProtKB/TrEMBL
	ENSSSCT00045052320.1	UniProtKB/TrEMBL
	ENSSSCT00045052431.1	UniProtKB/TrEMBL
	ENSSSCT00045052510.1	UniProtKB/TrEMBL
	ENSSSCT00050087707.1	UniProtKB/TrEMBL
	ENSSSCT00050087715.1	UniProtKB/TrEMBL
	ENSSSCT00050087723.1	UniProtKB/TrEMBL
	ENSSSCT00050087725.1	UniProtKB/TrEMBL
	ENSSSCT00055024686.1	UniProtKB/TrEMBL
	ENSSSCT00055024743.1	UniProtKB/TrEMBL
	ENSSSCT00055024781.1	UniProtKB/TrEMBL
	ENSSSCT00060005601.1	UniProtKB/TrEMBL
	ENSSSCT00060005605.1	UniProtKB/TrEMBL
	ENSSSCT00060005606.1	UniProtKB/TrEMBL
	ENSSSCT00065042685.1	UniProtKB/TrEMBL
	ENSSSCT00065042688.1	UniProtKB/TrEMBL
	ENSSSCT00065042693.1	UniProtKB/TrEMBL
	ENSSSCT00070049808.1	UniProtKB/TrEMBL
	ENSSSCT00070049812.1	UniProtKB/TrEMBL
Gene3D-CATH	NAD(P)-binding Rossmann-like Domain	UniProtKB/TrEMBL
InterPro	HSD17B7	UniProtKB/TrEMBL
	NAD(P)-bd_dom_sf	UniProtKB/TrEMBL
	SDR_fam	UniProtKB/TrEMBL
KEGG Report	ssc:100155418	UniProtKB/TrEMBL
NCBI Gene	HSD17B7	ENTREZGENE
PANTHER	3-KETO-STEROID REDUCTASE	UniProtKB/TrEMBL
	3-KETO-STEROID REDUCTASE/17-BETA-HYDROXYSTEROID DEHYDROGENASE 7	UniProtKB/TrEMBL
Pfam	adh_short	UniProtKB/TrEMBL
PRINTS	GDHRDH	UniProtKB/TrEMBL
Superfamily-SCOP	SSF51735	UniProtKB/TrEMBL
UniProt	A0A287ABG3	ENTREZGENE, UniProtKB/TrEMBL
	A0A480HNU3	ENTREZGENE, UniProtKB/TrEMBL
	A0A480TP00	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1VFD9_PIG	UniProtKB/TrEMBL
	A0A4X1VM69_PIG	UniProtKB/TrEMBL
	A0A8D0JAG7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0Q2K3_PIG	UniProtKB/TrEMBL
	A0A8D0S8P5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1D4I7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1TM42_PIG	UniProtKB/TrEMBL
	A0A8D2C527_PIG	UniProtKB/TrEMBL
	B5MBT7_PIG	UniProtKB/TrEMBL
	D0G6Y2	ENTREZGENE, UniProtKB/TrEMBL
	F1S213	ENTREZGENE
UniProt Secondary	A0A5G2QGH2	UniProtKB/TrEMBL
	F1S213	UniProtKB/TrEMBL
VGNC ID	VGNC:88988	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB