Message Center
{{ messageCount }} Messages
Watched Genes
{{$index + 1}}. {{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Watched Ontology Terms
{{$index + 1}}. {{ watchedTerm.term }} ({{watchedTerm.accId}})
{{gene.symbol}}: {{ gene.description }}
Save what matters to you
{{ loginError }}
Sign in with your RGD account
Gene: Mpzl1 (myelin protein zero-like 1) Rattus norvegicus
Analyze
Symbol:
Mpzl1
Name:
myelin protein zero-like 1
RGD ID:
1359140
Description:
Predicted to be involved in positive regulation of cell migration. Predicted to localize to integral component of plasma membrane. Orthologous to human MPZL1 (myelin protein zero like 1); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; acetylsalicylic acid.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
MGC93692; myelin protein zero-like protein 1
RGD Orthologs
Alliance Genes
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
MPZL1 (myelin protein zero like 1)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Mpzl1 (myelin protein zero-like 1)
HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Pan paniscus (bonobo/pygmy chimpanzee):
MPZL1 (myelin protein zero like 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
MPZL1 (myelin protein zero like 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Mpzl1 (myelin protein zero like 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
MPZL1 (myelin protein zero like 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
MPZL1 (myelin protein zero like 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Mpzl1 (myelin protein zero like 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
MPZL1 (myelin protein zero like 1)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Mus musculus (house mouse):
Mpzl1 (myelin protein zero-like 1)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Danio rerio (zebrafish):
mpzl1l (myelin protein zero-like 1 like)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 13 83,805,244 - 83,842,074 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 13 83,805,244 - 83,842,051 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 13 88,685,410 - 88,722,238 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 13 81,321,155 - 81,357,929 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 13 81,335,342 - 81,372,117 (-) NCBI Celera 13 77,565,342 - 77,602,116 (-) NCBI Celera Cytogenetic Map 13 q23 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Disease Annotations - CTD
1,2-dichloroethane increases expression ISO RGD:1550994 6480464 ethylene dichloride results in increased expression of MPZL1 mRNA CTD PMID:28960355 1,2-dimethylhydrazine multiple interactions ISO RGD:1550994 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MPZL1 mRNA CTD PMID:22206623 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of MPZL1 mRNA CTD PMID:17108234 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:1343477 6480464 Dihydrotestosterone results in increased expression of MPZL1 mRNA CTD PMID:29581250 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1550994 6480464 Tetrachlorodibenzodioxin affects the expression of MPZL1 mRNA CTD PMID:28922406 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:1343477 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MPZL1 mRNA CTD PMID:28628672 4-hydroxyphenyl retinamide increases expression ISO RGD:1550994 6480464 Fenretinide results in increased expression of MPZL1 mRNA CTD PMID:28973697 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of MPZL1 mRNA CTD PMID:24780913 acetylsalicylic acid increases expression EXP 6480464 Aspirin results in increased expression of MPZL1 mRNA CTD PMID:12800193 adenine decreases expression ISO RGD:1343477 6480464 Adenine results in decreased expression of MPZL1 mRNA CTD PMID:24211769 antirheumatic drug increases expression ISO RGD:1343477 6480464 Antirheumatic Agents results in increased expression of MPZL1 mRNA CTD PMID:24449571 atrazine increases expression ISO RGD:1343477 6480464 Atrazine results in increased expression of MPZL1 mRNA CTD PMID:22378314 benzo[a]pyrene increases expression ISO RGD:1550994 6480464 Benzoapyrene results in increased expression of MPZL1 mRNA CTD PMID:19770486 benzo[a]pyrene decreases methylation ISO RGD:1343477 6480464 Benzoapyrene results in decreased methylation of MPZL1 3' UTR CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:1343477 6480464 Benzoapyrene results in increased expression of MPZL1 mRNA CTD PMID:26238291 benzo[a]pyrene diol epoxide I increases expression ISO RGD:1343477 6480464 7 more ... CTD PMID:26238291 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MPZL1 mRNA CTD PMID:18164116 bis(2-ethylhexyl) phthalate increases expression ISO RGD:1343477 6480464 Diethylhexyl Phthalate results in increased expression of MPZL1 mRNA CTD PMID:31163220 bisphenol A decreases expression ISO RGD:1343477 6480464 bisphenol A results in decreased expression of MPZL1 mRNA CTD PMID:20678512 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of MPZL1 gene CTD PMID:28505145 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of MPZL1 mRNA CTD PMID:25181051 bisphenol F multiple interactions ISO RGD:1343477 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MPZL1 mRNA CTD PMID:28628672 butyric acid increases expression EXP 6480464 Butyric Acid results in increased expression of MPZL1 mRNA CTD PMID:12800193 carbon nanotube decreases expression ISO RGD:1550994 6480464 Nanotubes, Carbon analog results in decreased expression of MPZL1 mRNA CTD PMID:25620056 carbon nanotube increases expression ISO RGD:1550994 6480464 Nanotubes, Carbon results in increased expression of MPZL1 mRNA CTD PMID:25620056 chloroprene decreases expression ISO RGD:1550994 6480464 Chloroprene results in decreased expression of MPZL1 mRNA CTD PMID:23125180 choline multiple interactions ISO RGD:1550994 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MPZL1 mRNA CTD PMID:20938992 cisplatin decreases expression ISO RGD:1343477 6480464 Cisplatin results in decreased expression of MPZL1 mRNA CTD PMID:24211769 cobalt dichloride increases expression ISO RGD:1343477 6480464 cobaltous chloride results in increased expression of MPZL1 mRNA CTD PMID:19320972 copper(II) sulfate decreases expression ISO RGD:1343477 6480464 Copper Sulfate results in decreased expression of MPZL1 mRNA CTD PMID:19549813 cytarabine decreases expression ISO RGD:1343477 6480464 Cytarabine results in decreased expression of MPZL1 mRNA CTD PMID:21198554 dexamethasone multiple interactions ISO RGD:1343477 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MPZL1 mRNA CTD PMID:28628672 dibenz[a,h]anthracene decreases expression ISO RGD:1550994 6480464 1 more ... CTD PMID:26377693 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of MPZL1 mRNA CTD PMID:21266533 dorsomorphin multiple interactions ISO RGD:1343477 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:1343477 6480464 Doxorubicin results in decreased expression of MPZL1 mRNA CTD PMID:29803840 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of MPZL1 mRNA CTD PMID:31464424 ethyl methanesulfonate decreases expression ISO RGD:1343477 6480464 Ethyl Methanesulfonate results in decreased expression of MPZL1 mRNA CTD PMID:24211769 etoposide decreases expression ISO RGD:1343477 6480464 Etoposide results in decreased expression of MPZL1 mRNA CTD PMID:24211769 folic acid multiple interactions ISO RGD:1550994 6480464 [1 more ... CTD PMID:20938992 , PMID:22206623 formaldehyde decreases expression ISO RGD:1343477 6480464 Formaldehyde results in decreased expression of MPZL1 mRNA CTD PMID:23649840 furan increases expression EXP 6480464 furan results in increased expression of MPZL1 mRNA CTD PMID:27387713 hydroxyurea decreases expression ISO RGD:1343477 6480464 Hydroxyurea results in decreased expression of MPZL1 mRNA CTD PMID:24211769 indometacin multiple interactions ISO RGD:1343477 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MPZL1 mRNA CTD PMID:28628672 L-methionine multiple interactions ISO RGD:1550994 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MPZL1 mRNA CTD PMID:20938992 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of MPZL1 mRNA CTD PMID:30467583 methotrexate increases expression ISO RGD:1343477 6480464 Methotrexate results in increased expression of MPZL1 mRNA CTD PMID:24449571 methyl methanesulfonate decreases expression ISO RGD:1343477 6480464 Methyl Methanesulfonate results in decreased expression of MPZL1 mRNA CTD PMID:24211769 methylmercury chloride increases expression ISO RGD:1343477 6480464 methylmercuric chloride results in increased expression of MPZL1 mRNA CTD PMID:28001369 mifepristone decreases expression ISO RGD:1343477 6480464 Mifepristone results in decreased expression of MPZL1 mRNA CTD PMID:17584828 mitomycin C decreases expression ISO RGD:1343477 6480464 Mitomycin results in decreased expression of MPZL1 mRNA CTD PMID:24211769 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MPZL1 mRNA CTD PMID:18164116 nickel sulfate decreases expression ISO RGD:1343477 6480464 nickel sulfate results in decreased expression of MPZL1 mRNA CTD PMID:16780908 oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of MPZL1 mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of MPZL1 mRNA CTD PMID:25729387 paracetamol affects expression ISO RGD:1550994 6480464 Acetaminophen affects the expression of MPZL1 mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:1343477 6480464 Acetaminophen results in increased expression of MPZL1 mRNA CTD PMID:29067470 phenobarbital multiple interactions ISO RGD:1550994 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of MPZL1 mRNA] CTD PMID:19482888 phenobarbital affects expression ISO RGD:1550994 6480464 Phenobarbital affects the expression of MPZL1 mRNA CTD PMID:23091169 phenobarbital decreases expression ISO RGD:1550994 6480464 Phenobarbital results in decreased expression of MPZL1 mRNA CTD PMID:19270015 phenobarbital increases expression ISO RGD:1550994 6480464 Phenobarbital results in increased expression of MPZL1 mRNA CTD PMID:19482888 phenylmercury acetate increases expression ISO RGD:1343477 6480464 Phenylmercuric Acetate results in increased expression of MPZL1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1343477 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of MPZL1 mRNA CTD PMID:27188386 pirinixic acid increases expression ISO RGD:1550994 6480464 pirinixic acid results in increased expression of MPZL1 mRNA CTD PMID:23811191 sarin decreases expression ISO RGD:1343477 6480464 Sarin results in decreased expression of MPZL1 mRNA CTD PMID:19522546 SB 431542 multiple interactions ISO RGD:1343477 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... CTD PMID:27188386 sulforaphane decreases expression ISO RGD:1343477 6480464 sulforafan results in decreased expression of MPZL1 mRNA CTD PMID:26833863 sunitinib decreases expression ISO RGD:1343477 6480464 Sunitinib results in decreased expression of MPZL1 mRNA CTD PMID:31533062 tetrachloromethane increases expression ISO RGD:1550994 6480464 Carbon Tetrachloride results in increased expression of MPZL1 mRNA CTD PMID:31919559 thapsigargin decreases expression ISO RGD:1550994 6480464 Thapsigargin results in decreased expression of MPZL1 protein CTD PMID:24648495 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of MPZL1 mRNA CTD PMID:23411599 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of MPZL1 mRNA CTD PMID:25729387 topotecan increases expression EXP 6480464 Topotecan results in increased expression of MPZL1 mRNA CTD PMID:25729387 trichostatin A increases expression ISO RGD:1343477 6480464 trichostatin A results in increased expression of MPZL1 mRNA CTD PMID:24935251 trimellitic anhydride decreases expression ISO RGD:1550994 6480464 trimellitic anhydride results in decreased expression of MPZL1 mRNA CTD PMID:19042947 valproic acid increases expression ISO RGD:1343477 6480464 Valproic Acid results in increased expression of MPZL1 mRNA CTD PMID:23179753 more ... valproic acid multiple interactions ISO RGD:1343477 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of MPZL1 mRNA CTD PMID:27188386 vitamin E increases expression ISO RGD:1343477 6480464 Vitamin E results in increased expression of MPZL1 mRNA CTD PMID:19244175
References
Additional References at PubMed
Genomics
QTLs in Region (Rnor_6.0)
1354666 Bp244 Blood pressure QTL 244 4.9 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 13 1 107975663 Rat 1354666 Bp244 Blood pressure QTL 244 4.9 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 13 1 107975663 Rat 1354666 Bp244 Blood pressure QTL 244 4.9 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 13 1 107975663 Rat 1581570 Eae17 Experimental allergic encephalomyelitis QTL 17 4.1 nervous system integrity trait (VT:0010566) experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046) 13 12193394 108478121 Rat 7207885 Glom27 Glomerulus QTL 27 3.9 kidney glomerulus integrity trait (VT:0010546) kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139) 13 24502279 108770533 Rat 1354621 Rf47 Renal function QTL 47 3.7 kidney renin amount (VT:0010559) kidney renin level (CMO:0002166) 13 35301263 107975663 Rat 70181 BpQTLcluster11 Blood pressure QTL cluster 11 6.922 arterial blood pressure trait (VT:2000000) absolute change in mean arterial blood pressure (CMO:0000533) 13 36147533 99968921 Rat 70181 BpQTLcluster11 Blood pressure QTL cluster 11 6.922 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 13 36147533 99968921 Rat 70181 BpQTLcluster11 Blood pressure QTL cluster 11 6.922 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 13 36147533 99968921 Rat 70181 BpQTLcluster11 Blood pressure QTL cluster 11 6.922 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 13 36147533 99968921 Rat 61340 Bp25 Blood pressure QTL 25 4.2 0.004 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 13 39372927 84372927 Rat 10755495 Bp387 Blood pressure QTL 387 3.78 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 13 39501300 93652524 Rat 4889861 Pur29 Proteinuria QTL 29 13.8 0.005 total urine protein amount (VT:0000032) urine total protein excretion rate (CMO:0000756) 13 42310744 86833540 Rat 1331750 Bp220 Blood pressure QTL 220 2.98 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 13 42310744 87310744 Rat 70220 Bp55 Blood pressure QTL 55 5.75 arterial blood pressure trait (VT:2000000) blood pressure measurement (CMO:0000003) 13 42508345 87508345 Rat 61349 Bp31 Blood pressure QTL 31 5.75 arterial blood pressure trait (VT:2000000) blood pressure measurement (CMO:0000003) 13 42508345 87508345 Rat 1549897 Stresp12 Stress response QTL 12 3.35 stress-related behavior trait (VT:0010451) number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960) 13 43575717 88575717 Rat 619615 Bp80 Blood pressure QTL 80 0.0354 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 13 45676629 90676629 Rat 12879441 Bp396 Blood pressure QTL 396 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 13 51080989 96080989 Rat 1298066 Bp159 Blood pressure QTL 159 0.004 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 13 51569248 96569248 Rat 71119 Thym2 Thymus enlargement QTL 2 3.8 thymus mass (VT:0004954) thymus weight to body weight ratio (CMO:0000612) 13 51577824 90675199 Rat 1641901 Alcrsp6 Alcohol response QTL 6 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 13 57903612 102903612 Rat 1354655 Bp241 Blood pressure QTL 241 3.9 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 13 62975663 107975663 Rat 738026 Lnnr5 Liver neoplastic nodule remodeling QTL 5 3.29 liver integrity trait (VT:0010547) liver remodeling tumorous lesion number (CMO:0001461) 13 65008245 91629354 Rat 12879475 Bp400 Blood pressure QTL 400 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 13 66971778 111971778 Rat 2293687 Bss26 Bone structure and strength QTL 26 4.6 0.0001 femur morphology trait (VT:0000559) femur cross-sectional area (CMO:0001661) 13 71230858 114033958 Rat 2293702 Bss34 Bone structure and strength QTL 34 4.61 0.0001 femur strength trait (VT:0010010) femur midshaft polar moment of inertia (CMO:0001669) 13 71230858 114033958 Rat 7387280 Uae43 Urinary albumin excretion QTL 43 5.69 0.4174 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 13 72583716 114033958 Rat 1300166 Kidm6 Kidney mass QTL 6 3.93 kidney mass (VT:0002707) single kidney wet weight to body weight ratio (CMO:0000622) 13 74568378 92916783 Rat 1331783 Bp221 Blood pressure QTL 221 3.72886 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 13 74568378 92916783 Rat 8655945 Rf61 Renal function QTL 61 3.6 blood creatinine amount (VT:0005328) creatinine clearance (CMO:0000765) 13 74568378 92916783 Rat 10755455 Coatc13 Coat color QTL 13 0 coat/hair pigmentation trait (VT:0010463) pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812) 7 77694986 114033958 Rat 11530006 Niddm72 Non-insulin dependent diabetes mellitus QTL 72 0.001 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 13 79567081 86833540 Rat 8655959 Pur32 Proteinuria QTL 32 8.4 total urine protein amount (VT:0000032) urine total protein excretion rate (CMO:0000756) 13 79567081 103613733 Rat 738027 Lnnr6 Liver neoplastic nodule remodeling QTL 6 3.3 liver integrity trait (VT:0010547) liver remodeling tumorous lesion number (CMO:0001461) 13 80403559 91629354 Rat 2293341 Glom15 Glomerulus QTL 15 9.1 kidney glomerulus integrity trait (VT:0010546) kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269) 13 80403559 108770687 Rat