Mpzl1 (myelin protein zero-like 1)

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Gene: Mpzl1 (myelin protein zero-like 1) Rattus norvegicus

Analyze

Symbol:

Mpzl1

Name:

myelin protein zero-like 1

RGD ID:

1359140

Description:

Predicted to be involved in signal transduction. Predicted to act upstream of or within positive regulation of cell migration. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Orthologous to human MPZL1 (myelin protein zero like 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

MGC93692; myelin protein zero-like protein 1

RGD Orthologs

Human

Mouse

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MPZL1 (myelin protein zero like 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Mpzl1 (myelin protein zero-like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MPZL1 (myelin protein zero like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MPZL1 (myelin protein zero like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mpzl1 (myelin protein zero like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MPZL1 (myelin protein zero like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MPZL1 (myelin protein zero like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mpzl1 (myelin protein zero like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	MPZL1 (myelin protein zero like 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Mpzl1 (myelin protein zero-like 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mpzl1l (myelin protein zero-like 1 like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	77,852,467 - 77,889,305 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	77,852,467 - 77,896,616 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	80,470,736 - 80,507,456 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	13	81,774,724 - 81,811,446 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	13	79,021,768 - 79,058,475 (-)	NCBI	Rnor_WKY
Rnor_6.0	13	83,805,244 - 83,842,074 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	83,805,244 - 83,842,051 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	88,685,410 - 88,722,238 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	81,321,155 - 81,357,929 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	81,335,342 - 81,372,117 (-)	NCBI
Celera	13	77,565,342 - 77,602,116 (-)	NCBI		Celera
Cytogenetic Map	13	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Animal Mammary Neoplasms (ISO)

carcinoma (ISO)

Experimental Mammary Neoplasms (ISO)

gastrointestinal stromal tumor (ISO)

parathyroid carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetylsalicylic acid (EXP)

adenine (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

arotinoid acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-naphthoflavone (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butyric acid (EXP)

carbon nanotube (ISO)

CGP 52608 (ISO)

CHIR 99021 (ISO)

chloroprene (ISO)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cortisol (ISO)

cytarabine (ISO)

dexamethasone (ISO)

dibenz[a,h]anthracene (ISO)

dibutyl phthalate (EXP)

diethyl maleate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethyl methanesulfonate (ISO)

etoposide (ISO)

folic acid (ISO)

formaldehyde (ISO)

furan (EXP)

hydroxyurea (ISO)

indometacin (ISO)

ivermectin (ISO)

L-ascorbic acid (ISO)

L-ascorbic acid 2-phosphate (ISO)

L-methionine (ISO)

methapyrilene (EXP)

methotrexate (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

mifepristone (ISO)

mitomycin C (ISO)

N-nitrosodiethylamine (EXP)

nickel sulfate (ISO)

oxaliplatin (EXP)

paracetamol (EXP,ISO)

paraquat (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

sarin (ISO)

SB 431542 (ISO)

sulforaphane (ISO)

sunitinib (ISO)

tetrachloromethane (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

topotecan (EXP)

trichostatin A (ISO)

trimellitic anhydride (ISO)

valproic acid (ISO)

vitamin E (ISO)

XAV939 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of cell migration (ISO)

signal transduction (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IBA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
6.	Dissecting the interaction of SHP-2 with PZR, an immunoglobulin family protein containing immunoreceptor tyrosine-based inhibitory motifs.	Zhao R and Zhao ZJ, J Biol Chem 2000 Feb 25;275(8):5453-9.
7.	Cell surface glycoprotein PZR is a major mediator of concanavalin A-induced cell signaling.	Zhao R, etal., J Biol Chem 2002 Mar 8;277(10):7882-8. Epub 2001 Dec 20.

Additional References at PubMed

PMID:15489334	PMID:17440960	PMID:19581412	PMID:21423176

Genomics

Comparative Map Data

Mpzl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	77,852,467 - 77,889,305 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	77,852,467 - 77,896,616 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	80,470,736 - 80,507,456 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	13	81,774,724 - 81,811,446 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	13	79,021,768 - 79,058,475 (-)	NCBI	Rnor_WKY
Rnor_6.0	13	83,805,244 - 83,842,074 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	83,805,244 - 83,842,051 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	88,685,410 - 88,722,238 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	81,321,155 - 81,357,929 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	81,335,342 - 81,372,117 (-)	NCBI
Celera	13	77,565,342 - 77,602,116 (-)	NCBI		Celera
Cytogenetic Map	13	q23	NCBI

MPZL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	167,721,982 - 167,791,919 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	1	167,721,192 - 167,791,919 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	167,691,219 - 167,761,156 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	165,957,832 - 166,026,684 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	164,422,865 - 164,491,716	NCBI
Celera	1	140,800,446 - 140,870,412 (+)	NCBI		Celera
Cytogenetic Map	1	q24.2	NCBI
HuRef	1	138,937,273 - 139,007,435 (+)	NCBI		HuRef
CHM1_1	1	169,113,411 - 169,183,386 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	167,073,478 - 167,143,403 (+)	NCBI		T2T-CHM13v2.0

Mpzl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	165,419,745 - 165,462,144 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	165,419,809 - 165,462,107 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	165,592,176 - 165,634,541 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	165,592,240 - 165,634,538 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	167,522,312 - 167,564,672 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	167,428,915 - 167,471,196 (-)	NCBI		MGSCv36	mm8
Celera	1	168,036,719 - 168,079,026 (-)	NCBI		Celera
Cytogenetic Map	1	H2.3	NCBI

MPZL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	146,937,540 - 147,004,503 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	146,937,479 - 147,004,503 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	1	143,154,682 - 143,221,780 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

MPZL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	30,670,506 - 30,741,464 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	30,672,840 - 30,741,484 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	30,209,736 - 30,278,606 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	30,491,188 - 30,560,174 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	30,491,246 - 30,559,831 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	30,331,164 - 30,400,236 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	30,362,246 - 30,431,459 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	30,598,684 - 30,669,887 (-)	NCBI		UU_Cfam_GSD_1.0

Mpzl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	100,492,287 - 100,511,980 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936481	18,340,269 - 18,358,729 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MPZL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	83,235,714 - 83,316,405 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	83,235,712 - 83,309,620 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	90,911,481 - 90,985,387 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MPZL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	61,248,180 - 61,309,746 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	61,245,562 - 61,309,881 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	62,970,101 - 63,033,207 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mpzl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624826	5,760,008 - 5,831,641 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624826	5,760,039 - 5,830,228 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Position Markers

RH141095

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	77,852,622 - 77,852,826 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	83,805,400 - 83,805,603	NCBI	Rnor6.0
Rnor_5.0	13	88,685,566 - 88,685,769	UniSTS	Rnor5.0
RGSC_v3.4	13	81,321,311 - 81,321,514	UniSTS	RGSC3.4
Celera	13	77,565,498 - 77,565,701	UniSTS
Cytogenetic Map	13	q23	UniSTS

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	101056920	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	8897350	101631289	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	20605871	101339738	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	30395351	101056920	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	31241331	93395974	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	34535218	79535218	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	37262092	82262092	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	37374509	82374509	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	37374509	82374509	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	37415584	80753406	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	37415584	82415584	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	38433408	83433408	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	39754544	84754544	Rat
12879444	Bp397	Blood pressure QTL 397			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45049404	90049404	Rat
12879471	Bp398	Blood pressure QTL 398			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45514719	90514719	Rat
12879441	Bp396	Blood pressure QTL 396			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45699983	90699983	Rat
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	46088046	91088046	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	46197976	84753113	Rat
1641901	Alcrsp6	Alcohol response QTL 6			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	13	52362171	97362171	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	56056920	101056920	Rat
738026	Lnnr5	Liver neoplastic nodule remodeling QTL 5	3.29		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	59874408	85581182	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	61825626	106807694	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	65103704	106807694	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	65103704	106807694	Rat
8655945	Rf61	Renal function QTL 61	3.6		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	13	69060519	86800898	Rat
1331783	Bp221	Blood pressure QTL 221	3.72886		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	69060519	86800898	Rat
1300166	Kidm6	Kidney mass QTL 6	3.93		kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	13	69060519	86800898	Rat
11530006	Niddm72	Non-insulin dependent diabetes mellitus QTL 72		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	74023918	80753406	Rat
8655959	Pur32	Proteinuria QTL 32	8.4		total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	74023918	97213863	Rat
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	74862117	85581182	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	74862117	101339893	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	258
Count of miRNA genes:	178
Interacting mature miRNAs:	213
Transcripts:	ENSRNOT00000004376
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	39	23	12	18	12	4	4	74	35	40	11	4
Low		4	34	29	1	29	4	7			1		4
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001007728	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250180	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC078916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232192	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000244	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000004376 ⟹ ENSRNOP00000004376

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	77,852,467 - 77,889,323 (-)	Ensembl
Rnor_6.0 Ensembl	13	83,805,244 - 83,842,051 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000093821 ⟹ ENSRNOP00000089948

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	77,852,467 - 77,896,616 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099714 ⟹ ENSRNOP00000088248

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	77,852,467 - 77,889,292 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000101772 ⟹ ENSRNOP00000084855

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	77,853,825 - 77,889,323 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000113749 ⟹ ENSRNOP00000097312

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	77,852,467 - 77,869,056 (-)	Ensembl

RefSeq Acc Id:

NM_001007728 ⟹ NP_001007729

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	77,852,467 - 77,889,245 (-)	NCBI
Rnor_6.0	13	83,805,244 - 83,842,018 (-)	NCBI
Rnor_5.0	13	88,685,410 - 88,722,238 (-)	NCBI
RGSC_v3.4	13	81,321,155 - 81,357,929 (-)	RGD
Celera	13	77,565,342 - 77,602,116 (-)	RGD

Sequence:

show sequence

GTCCTCGCGCCCGCAGCCGCGATCCGGAGCTGTGTGGTCTCAGGCAAGCGAGCCAACCGCTGCG
GGAACCCGGGCGGAACGGAGCGGCGGGAGCAGGATGGCAGAGGCCGTCGGAGCCGTGACATTGA
TTGCGGCCCCGGCCCGCCGGCGCTGGCTGTGGTCGGCGCTAGCCGCGATGCTCGGGCTGTTGAC
AGCTAGAATATCAGCCTTGGAGGTACATACTCCTAAAGAAATCTTTGTGGTGAATGGGACACAA
GGGAAGCTCACGTGCACGTTTGACTCTCCTAATACAACTGGGTGGTTGACCACCGTCTCCTGGA
GCTTCCAGCCAGAAGGCACCGACAGCGCCGTGTCGTTTTTCCACTACTCACAAGGACAAGTGTA
CATCGGGGATTATCCACCGTTTAAAGACCGAGTCACCTGGGCTGGGGACCTTGACAAGAAAGAT
GCATCGATCAATATAGAAAACATTCAGGCTGTTCACAATGGCACCTATATCTGCGATGTCAAAA
ACCCTCCTGACATTGTTGTGCGGCCTGGGCAGATTAGGCTCCATGTGGTGGAAATAGACAACCT
GCTGGTGTTCCTGGTTTGGGTGGTGGTGGGCACTGTCACTGCTGTGGTCCTTGGGCTCACTCTA
CTCATCAGCTTGGTCCTGGTCGTCCTCTACAGACGGAAGCATTCGAAGCGGGATTATACCGGCT
GCAGTACCTCAGAGCGTTTGTCACCAGTTAAGCAGGCTCCACGGAAGTGTCCCTCCGACACAGA
GGGTCTAGTAAAGAGTCCGCCTTCCGCCGGATCTCACCAGGGCCCAGTCATATACGCACAGTTA
GACCACTCTGGCGGACATCACAGTGGCAAGATTAATAAGTCAGAGTCTGTTGTGTATGCGGACA
TCCGGAAAGACTAAGAGAACACCCCAAATATTTCTTAAGCAAGAAACAAATCCAAGCGGACTCT
TGTGAGGAAAGTGTCCATAACCATGTGTGGCCTTGAAGCAAGGACAAGCACGTGTGTATTCAGA
GAGAGAAGAAAATGTGTATAAAGGAAATGTGTATTCTATTTAATCTTCCGATGTGAGAGGCCAA
TGTTGCATGATGAGATGGTATGAGTCTATGTATGTGTAAGTTGTCTTGCTGTTTCTCTATATTC
TTTCAGAGTCATTTCCAGCTGGAAAGTTTCAGAAACATCCTGTCACCCCGGGATATGGTTTGCC
TTATTGAAGACTCTGCAGAACCCTTAGGCTTCCCAACAGACGTGGCCTTTTCATCAAGGGCTCA
ACCAGTCTAAGCATTTCTTGTAGTTAGAGAGTGAGATGTTGAGTGGAAGTGAGTGTCTCACAAT
ATCAGGACCGTTTTGTTCTGTGCCCGTGCTAGCTGATCGATGCCATCCATTAACCATGCCACCA
GAGGATGGTTTGAGAGGTTTTTGTTGATGCTTTTCTAAAATTTGAGGGACTTTTGAGCTTGAGA
GCATCGCCATCCTGCTATTAGCTAAGAGCTCACCAGTGAGTCGGCTGACTGAGGCCGCGGTTGT
GGTTAAAAGGGTACAAGTTACAGCACCCCAGCATGACATTAACATGTGAAGGGTACAAGTTACA
GCACCCCAGCATGACATTAACATGTGAAAGATGTCAGAGGAAGTCAGCATCTTGCTTCTCCTCT
CCTTAGGGATTCAGTGAATGATCGTACATTCTAGATACCCCAGGTGCTTGATGGTCTCCTTGTA
GTGCCGAGACAGAGACAGTGCATACGGTGCTAGGAGTGGGCTCTGTTCAAATGACACCTCCTCT
TAGGGGCTTTCTGCATCTGGCTCCGTGACCTCCCTGCCCAGTTAGAACCAAACCCTCTGTTGGC
CCAAGCCAACCTTCTTCCCTAGGCAGAAACAGTTAGCTGCTGGCATCCTGGACTGAGTCTGCAG
CCTGGTTCTAGCTGCTTACAGGACAGCGTGCAAACCTCAGGGTCTAACTCCACACCCCACCTCC
TTGGAGCATCCGGTCTCTTTCCGGAAACTCTGTCTTCGGGCCTAGCTACAGATAACAGTGAGGT
CACATCCACACGGCAGACCTGTGCTTCCTGTGTCTTCTGACCAGAAGAGTGCATGCGATTTGAG
AAGAGACACTTAAAAGTGATAGCTTTTTAAAATCCCTGTCTGTATTTTCTCACGGAAATGTATC
CAGCTAGGAGAGATATCAAGTTCATTGTTACTTTTTGATATTTTCATTTGTACTTCTGTGACTA
TTTTAATACATCTTTTTTGATTTCTGAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006250180 ⟹ XP_006250242

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	77,852,467 - 77,889,305 (-)	NCBI
Rnor_6.0	13	83,805,244 - 83,842,074 (-)	NCBI
Rnor_5.0	13	88,685,410 - 88,722,238 (-)	NCBI

Sequence:

show sequence

CTGAGGGCTGGCGGTTGGCCACTGGGGCCGGGAGCAGGGAGCTGTGGCGTGGAGGTGTCCTCGC
GCCCGCAGCCGCGATCCGGAGCTGTGTGGTCTCAGGCAAGCGAGCCAACCGCTGCGGGAACCCG
GGCGGAACGGAGCGGCGGGAGCAGGATGGCAGAGGCCGTCGGAGCCGTGACATTGATTGCGGCC
CCGGCCCGCCGGCGCTGGCTGTGGTCGGCGCTAGCCGCGATGCTCGGGCTGTTGACAGCTAGAA
TATCAGCCTTGGAGGTACATACTCCTAAAGAAATCTTTGTGGTGAATGGGACACAAGGGAAGCT
CACGTGCACGTTTGACTCTCCTAATACAACTGGGTGGTTGACCACCGTCTCCTGGAGCTTCCAG
CCAGAAGGCACCGACAGCGCCGTGTCGTTTTTCCACTACTCACAAGGACAAGTGTACATCGGGG
ATTATCCACCGTTTAAAGACCGAGTCACCTGGGCTGGGGACCTTGACAAGAAAGATGCATCGAT
CAATATAGAAAACATTCAGGCTGTTCACAATGGCACCTATATCTGCGATGTCAAAAACCCTCCT
GACATTGTTGTGCGGCCTGGGCAGATTAGGCTCCATGTGGTGGAAATAGACAACCTGCTGGTGT
TCCTGGTTTGGGTGGTGGTGGGCACTGTCACTGCTGTGGTCCTTGGGCTCACTCTACTCATCAG
CTTGGTCCTGGTCGTCCTCTACAGACGGAAGCATTCGAAGCGGGATTATACCGGGGCCCAGTCA
TATACGCACAGTTAGACCACTCTGGCGGACATCACAGTGGCAAGATTAATAAGTCAGAGTCTGT
TGTGTATGCGGACATCCGGAAAGACTAAGAGAACACCCCAAATATTTCTTAAGCAAGAAACAAA
TCCAAGCGGACTCTTGTGAGGAAAGTGTCCATAACCATGTGTGGCCTTGAAGCAAGGACAAGCA
CGTGTGTATTCAGAGAGAGAAGAAAATGTGTATAAAGGAAATGTGTATTCTATTTAATCTTCCG
ATGTGAGAGGCCAATGTTGCATGATGAGATGGTATGAGTCTATGTATGTGTAAGTTGTCTTGCT
GTTTCTCTATATTCTTTCAGAGTCATTTCCAGCTGGAAAGTTTCAGAAACATCCTGTCACCCCG
GGATATGGTTTGCCTTATTGAAGACTCTGCAGAACCCTTAGGCTTCCCAACAGACGTGGCCTTT
TCATCAAGGGCTCAACCAGTCTAAGCATTTCTTGTAGTTAGAGAGTGAGATGTTGAGTGGAAGT
GAGTGTCTCACAATATCAGGACCGTTTTGTTCTGTGCCCGTGCTAGCTGATCGATGCCATCCAT
TAACCATGCCACCAGAGGATGGTTTGAGAGGTTTTTGTTGATGCTTTTCTAAAATTTGAGGGAC
TTTTGAGCTTGAGAGCATCGCCATCCTGCTATTAGCTAAGAGCTCACCAGTGAGTCGGCTGACT
GAGGCCGCGGTTGTGGTTAAAAGGGTACAAGTTACAGCACCCCAGCATGACATTAACATGTGAA
GGGTACAAGTTACAGCACCCCAGCATGACATTAACATGTGAAAGATGTCAGAGGAAGTCAGCAT
CTTGCTTCTCCTCTCCTTAGGGATTCAGTGAATGATCGTACATTCTAGATACCCCAGGTGCTTG
ATGGTCTCCTTGTAGTGCCGAGACAGAGACAGTGCATACGGTGCTAGGAGTGGGCTCTGTTCAA
ATGACACCTCCTCTTAGGGGCTTTCTGCATCTGGCTCCGTGACCTCCCTGCCCAGTTAGAACCA
AACCCTCTGTTGGCCCAAGCCAACCTTCTTCCCTAGGCAGAAACAGTTAGCTGCTGGCATCCTG
GACTGAGTCTGCAGCCTGGTTCTAGCTGCTTACAGGACAGCGTGCAAACCTCAGGGTCTAACTC
CACACCCCACCTCCTTGGAGCATCCGGTCTCTTTCCGGAAACTCTGTCTTCGGGCCTAGCTACA
GATAACAGTGAGGTCACATCCACACGGCAGACCTGTGCTTCCTGTGTCTTCTGACCAGAAGAGT
GCATGCGATTTGAGAAGAGACACTTAAAAGTGATAGCTTTTTAAAATCCCTGTCTGTATTTTCT
CACGGAAATGTATCCAGCTAGGAGAGATATCAAGTTCATTGTTACTTTTTGATATTTTCATTTG
TACTTCTGTGACTATTTTAATACATCTTTTTTGATTTCTGAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001007729	(Get FASTA)	NCBI Sequence Viewer
	XP_006250242	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH78916	(Get FASTA)	NCBI Sequence Viewer
	EDM09320	(Get FASTA)	NCBI Sequence Viewer
	EDM09321	(Get FASTA)	NCBI Sequence Viewer
	EDM09322	(Get FASTA)	NCBI Sequence Viewer
	EDM09323	(Get FASTA)	NCBI Sequence Viewer
	Q6AYT8	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001007729 ⟸ NM_001007728
- Peptide Label:	precursor
- UniProtKB:	Q6AYT8 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAEAVGAVTLIAAPARRRWLWSALAAMLGLLTARISALEVHTPKEIFVVNGTQGKLTCTFDSPN TTGWLTTVSWSFQPEGTDSAVSFFHYSQGQVYIGDYPPFKDRVTWAGDLDKKDASINIENIQAV HNGTYICDVKNPPDIVVRPGQIRLHVVEIDNLLVFLVWVVVGTVTAVVLGLTLLISLVLVVLYR RKHSKRDYTGCSTSERLSPVKQAPRKCPSDTEGLVKSPPSAGSHQGPVIYAQLDHSGGHHSGKI NKSESVVYADIRKD hide sequence

RefSeq Acc Id:

XP_006250242 ⟸ XM_006250180

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAEAVGAVTLIAAPARRRWLWSALAAMLGLLTARISALEVHTPKEIFVVNGTQGKLTCTFDSPN
TTGWLTTVSWSFQPEGTDSAVSFFHYSQGQVYIGDYPPFKDRVTWAGDLDKKDASINIENIQAV
HNGTYICDVKNPPDIVVRPGQIRLHVVEIDNLLVFLVWVVVGTVTAVVLGLTLLISLVLVVLYR
RKHSKRDYTGAQSYTHS

hide sequence

RefSeq Acc Id:

ENSRNOP00000004376 ⟸ ENSRNOT00000004376

RefSeq Acc Id:

ENSRNOP00000088248 ⟸ ENSRNOT00000099714

RefSeq Acc Id:

ENSRNOP00000084855 ⟸ ENSRNOT00000101772

RefSeq Acc Id:

ENSRNOP00000089948 ⟸ ENSRNOT00000093821

RefSeq Acc Id:

ENSRNOP00000097312 ⟸ ENSRNOT00000113749

Protein Domains

Ig-like Ig-like V-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AYT8-F1-model_v2	AlphaFold	Q6AYT8	1-270	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698961

Promoter ID:

EPDNEW_R9486

Type:

initiation region

Name:

Mpzl1_1

Description:

myelin protein zero-like 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	83,842,054 - 83,842,114	EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)

ACI/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN-Lx/CubMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BUF/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH2/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH3/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

DA/OlaHsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/DuCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE16/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE18/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GK/FarMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB10/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB2/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB20/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB31/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB4/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEW/Crl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF10A/StmMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF11/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1A/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1C/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF2B/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF3/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF4/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LH/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LL/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LN/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/NRrrcMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MR/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MWF/Hsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

PVG/Seac (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHR/OlalpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/A3NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SR/JrHsd (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SS/JrHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WAG/RijCrl (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WN/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359140	AgrOrtholog
BioCyc Gene	G2FUF-17566	BioCyc
Ensembl Genes	ENSRNOG00000003248	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000004376	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000084855.1	UniProtKB/TrEMBL
	ENSRNOP00000088248	ENTREZGENE
	ENSRNOP00000088248.1	UniProtKB/TrEMBL
	ENSRNOP00000089948.1	UniProtKB/TrEMBL
	ENSRNOP00000097312.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000004376	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000093821.1	UniProtKB/TrEMBL
	ENSRNOT00000099714	ENTREZGENE
	ENSRNOT00000099714.1	UniProtKB/TrEMBL
	ENSRNOT00000101772.1	UniProtKB/TrEMBL
	ENSRNOT00000113749.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7096438	IMAGE-MGC_LOAD
InterPro	Ig-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_sub	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MPZL1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Myelin_P0-rel	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:360871	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93692	IMAGE-MGC_LOAD
NCBI Gene	360871	ENTREZGENE
PANTHER	PTHR13869	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR13869:SF19	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	V-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Mpzl1	PhenoGen
PRINTS	MYELINP0	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	IGv	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SM00409	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I5ZYX9_RAT	UniProtKB/TrEMBL
	A0A8I6A952_RAT	UniProtKB/TrEMBL
	A0A8I6A9E7_RAT	UniProtKB/TrEMBL
	A0A8I6ASF7_RAT	UniProtKB/TrEMBL
	MPZL1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-07-29	Mpzl1	myelin protein zero-like 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD