Gene: Ncf2 (neutrophil cytosolic factor 2) Rattus norvegicus
Symbol: Ncf2
Name: neutrophil cytosolic factor 2
Description: ENCODES a protein that exhibits protein C-terminus binding (ortholog); Rac GTPase binding (ortholog); superoxide-generating NADPH oxidase activity (ortholog); INVOLVED IN aging; cellular response to hormone stimulus; positive regulation of blood pressure; PARTICIPATES IN Leishmania infection pathway; phagocytosis pathway; ASSOCIATED WITH decreased NAD(P)H oxidase activity; decreased susceptibility to hypertension; ASSOCIATED WITH Burns; diabetes mellitus, experimental; Hypertension; FOUND IN cytoplasm; membrane; acrosomal vesicle (ortholog); INTERACTS WITH 17beta-estradiol; aflatoxin B1; AICA ribonucleotide
Type: protein-coding
Also known as: LOC364018; NCF-2; neutrophil cytosol factor 2; neutrophil NADPH oxidase factor 2
Homo sapiens (human) : NCF2 (neutrophil cytosolic factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Ncf2 (neutrophil cytosolic factor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncf2 (neutrophil cytosolic factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NCF2 (neutrophil cytosolic factor 2)
Canis lupus familiaris (dog) : NCF2 (neutrophil cytosolic factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncf2 (neutrophil cytosolic factor 2)
more info ...
Allele / Splice: Ncf2em1Mcwi   Ncf2em4Mcwi  
Genetic Models: SS-Tg(Slc12a1-Ncf2-2A-Luc)-Ncf2em1Mcwi SS-Nox4em2Ncf2em1Mcwi SS-Ncf2em1Mcwi-/- SS-Ncf2em4Mcwi SS-Ncf2em1Mcwi
Is Marker For: Strains:   SS.BN-(D13Rat151-D13Rat197)-Tg(Slc12a1-Ncf2-2A-Luc)26Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01370,226,441 - 70,259,019 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01375,197,561 - 75,229,600 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41367,806,516 - 67,834,105 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11367,797,870 - 67,848,218 (+)NCBI
Celera1364,862,007 - 64,890,467 (+)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Ncf2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309424
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2018-02-06
Status: ACTIVE