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Gene: Rnasel (ribonuclease L) Rattus norvegicus
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Symbol: Rnasel
Name: ribonuclease L
Description: Exhibits rRNA binding activity and ribonuclease activity. Involved in rRNA processing. Localizes to the nuclear matrix. Human ortholog(s) of this gene implicated in Lynch syndrome and prostate cancer. Orthologous to human RNASEL (ribonuclease L); PARTICIPATES IN hepatitis C pathway; influenza A pathway; INTERACTS WITH 4,4'-diaminodiphenylmethane; ammonium chloride; cobalt dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 2-5A-dependent ribonuclease; ribonuclease L (2 5-oligoisoadenylate synthetase-dependent); ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent); ribonuclease L (2, 5-oligoisoadenylate synthetase-dependent)
Orthologs:
Homo sapiens (human) : RNASEL (ribonuclease L)  HGNC  Alliance
Mus musculus (house mouse) : Rnasel (ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnasel (ribonuclease L)
Pan paniscus (bonobo/pygmy chimpanzee) : RNASEL (ribonuclease L)
Canis lupus familiaris (dog) : RNASEL (ribonuclease L)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnasel (ribonuclease L)
Sus scrofa (pig) : RNASEL (ribonuclease L)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01371,188,712 - 71,202,636 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1371,192,142 - 71,202,625 (+)Ensembl
Rnor_5.01376,153,998 - 76,167,666 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41368,822,013 - 68,829,264 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11368,836,092 - 68,843,336 (+)NCBI
Celera1365,801,918 - 65,809,169 (+)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Rnasel
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 727933
Created: 2003-11-05
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.