Cryzl2 (crystallin zeta like 2) - Rat Genome Database

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Gene: Cryzl2 (crystallin zeta like 2) Rattus norvegicus
Analyze
Symbol: Cryzl2
Name: crystallin zeta like 2
RGD ID: 1304982
Description: Predicted to enable several functions, including NADPH binding activity; NADPH:quinone reductase activity; and protein homodimerization activity. Predicted to be involved in NADP metabolic process. Orthologous to human TP53I3 (tumor protein p53 inducible protein 3); INTERACTS WITH aristolochic acid (ortholog); fipronil (ortholog); N,N-diethyl-m-toluamide (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC289138; quinone oxidoreductase-like protein 2; RGD1304982; similar to RIKEN cDNA 2810025M15; Tp53i3; tumor protein p53 inducible protein 3
RGD Orthologs
Human
Mouse
Mouse
Dog
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21369,612,605 - 69,655,018 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1369,620,792 - 69,652,475 (+)Ensembl
Rnor_6.01375,101,759 - 75,145,967 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1375,105,615 - 75,143,441 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01380,021,276 - 80,062,430 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41372,724,644 - 72,756,267 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11372,687,354 - 72,770,280 (+)NCBI
Celera1369,451,486 - 69,481,415 (+)NCBICelera
Cytogenetic Map13q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:19349281   PMID:23376485  


Genomics

Comparative Map Data
Cryzl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21369,612,605 - 69,655,018 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1369,620,792 - 69,652,475 (+)Ensembl
Rnor_6.01375,101,759 - 75,145,967 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1375,105,615 - 75,143,441 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01380,021,276 - 80,062,430 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41372,724,644 - 72,756,267 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11372,687,354 - 72,770,280 (+)NCBI
Celera1369,451,486 - 69,481,415 (+)NCBICelera
Cytogenetic Map13q22NCBI
CRYZL2P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381178,006,136 - 178,038,007 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1178,006,136 - 178,037,950 (-)EnsemblGRCh38hg38GRCh38
GRCh371177,975,271 - 178,007,142 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361176,243,839 - 176,268,841 (-)NCBINCBI36hg18NCBI36
Celera1151,084,173 - 151,116,201 (-)NCBI
Cytogenetic Map1q25.2NCBI
HuRef1149,202,732 - 149,234,611 (-)NCBIHuRef
CHM1_11179,399,190 - 179,431,057 (-)NCBICHM1_1
T2T-CHM13v2.01177,360,910 - 177,392,778 (-)NCBI
Gm20348
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39124,860,475 - 4,867,155 (+)NCBIGRCm39mm39
GRCm39 Ensembl124,860,494 - 4,867,142 (+)Ensembl
GRCm38124,810,475 - 4,817,155 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37124,817,300 - 4,823,951 (+)NCBIGRCm37mm9NCBIm37
Celera124,742,037 - 4,748,688 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map122.09NCBI
Cryzl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391157,280,082 - 157,317,570 (+)NCBIGRCm39mm39
GRCm39 Ensembl1157,286,147 - 157,320,208 (+)Ensembl
GRCm381157,455,718 - 157,490,000 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1157,458,577 - 157,492,638 (+)EnsemblGRCm38mm10GRCm38
MGSCv371159,388,713 - 159,418,864 (+)NCBIGRCm37mm9NCBIm37
MGSCv361159,295,259 - 159,325,410 (+)NCBImm8
Celera1159,867,795 - 159,899,371 (+)NCBICelera
Cytogenetic Map1H1NCBI
TP53I3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11718,560,123 - 18,566,588 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1718,560,240 - 18,565,958 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1718,458,253 - 18,464,493 (-)NCBI
ROS_Cfam_1.01718,730,671 - 18,736,870 (-)NCBI
ROS_Cfam_1.0 Ensembl1718,730,610 - 18,736,690 (-)Ensembl
UMICH_Zoey_3.11718,571,400 - 18,577,848 (-)NCBI

Position Markers
BM385036  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21369,622,041 - 69,622,200 (+)MAPPERmRatBN7.2
Rnor_6.01375,113,023 - 75,113,181NCBIRnor6.0
Rnor_5.01380,030,673 - 80,030,831UniSTSRnor5.0
RGSC_v3.41372,725,758 - 72,725,916UniSTSRGSC3.4
Celera1369,452,600 - 69,452,758UniSTS
RH 3.4 Map13408.7UniSTS
Cytogenetic Map13q22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
4889861Pur29Proteinuria QTL 2913.80.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135849787273485113Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)135949252277046890Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)136906051977046890Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:236
Count of miRNA genes:157
Interacting mature miRNAs:178
Transcripts:ENSRNOT00000006924
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 43 45 35 10 35 8 10 2 31 26 11 8
Low 1 12 6 9 6 1 72 4 15
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001113775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC158771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000006924   ⟹   ENSRNOP00000006924
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1369,620,792 - 69,652,475 (+)Ensembl
Rnor_6.0 Ensembl1375,111,778 - 75,143,441 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076653   ⟹   ENSRNOP00000068232
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1369,620,792 - 69,651,994 (+)Ensembl
Rnor_6.0 Ensembl1375,105,615 - 75,124,344 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000100806   ⟹   ENSRNOP00000097423
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1369,620,792 - 69,651,950 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116185   ⟹   ENSRNOP00000079255
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1369,623,954 - 69,652,475 (+)Ensembl
RefSeq Acc Id: NM_001113775   ⟹   NP_001107247
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,620,923 - 69,652,475 (+)NCBI
Rnor_6.01375,111,909 - 75,143,424 (+)NCBI
Rnor_5.01380,021,276 - 80,062,430 (+)NCBI
RGSC_v3.41372,724,644 - 72,756,267 (+)RGD
Celera1369,451,486 - 69,481,415 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250040   ⟹   XP_006250102
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,620,679 - 69,655,018 (+)NCBI
Rnor_6.01375,111,579 - 75,145,967 (+)NCBI
Rnor_5.01380,021,276 - 80,062,430 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090474   ⟹   XP_038946402
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,612,727 - 69,655,018 (+)NCBI
RefSeq Acc Id: XM_039090475   ⟹   XP_038946403
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,620,677 - 69,655,018 (+)NCBI
RefSeq Acc Id: XM_039090476   ⟹   XP_038946404
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,612,727 - 69,655,018 (+)NCBI
RefSeq Acc Id: XM_039090477   ⟹   XP_038946405
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,620,675 - 69,655,018 (+)NCBI
RefSeq Acc Id: XM_039090478   ⟹   XP_038946406
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,620,819 - 69,655,018 (+)NCBI
RefSeq Acc Id: XM_039090479   ⟹   XP_038946407
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,614,627 - 69,655,018 (+)NCBI
RefSeq Acc Id: XM_039090480   ⟹   XP_038946408
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,612,605 - 69,655,018 (+)NCBI
RefSeq Acc Id: XM_039090481   ⟹   XP_038946409
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,612,727 - 69,655,018 (+)NCBI
RefSeq Acc Id: XM_039090482   ⟹   XP_038946410
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,615,350 - 69,655,018 (+)NCBI
RefSeq Acc Id: XM_039090483   ⟹   XP_038946411
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,614,600 - 69,655,018 (+)NCBI
RefSeq Acc Id: XM_039090484   ⟹   XP_038946412
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,620,621 - 69,633,405 (+)NCBI
RefSeq Acc Id: XR_005492221
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,620,679 - 69,655,018 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001107247   ⟸   NM_001113775
- Sequence:
RefSeq Acc Id: XP_006250102   ⟸   XM_006250040
- Peptide Label: isoform X1
- UniProtKB: B0BNC9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006924   ⟸   ENSRNOT00000006924
RefSeq Acc Id: ENSRNOP00000068232   ⟸   ENSRNOT00000076653
RefSeq Acc Id: XP_038946408   ⟸   XM_039090480
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038946402   ⟸   XM_039090474
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038946404   ⟸   XM_039090476
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038946409   ⟸   XM_039090481
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038946411   ⟸   XM_039090483
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038946407   ⟸   XM_039090479
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038946410   ⟸   XM_039090482
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038946412   ⟸   XM_039090484
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038946405   ⟸   XM_039090477
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038946403   ⟸   XM_039090475
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038946406   ⟸   XM_039090478
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000097423   ⟸   ENSRNOT00000100806
RefSeq Acc Id: ENSRNOP00000079255   ⟸   ENSRNOT00000116185

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0BNC9-F1-model_v2 AlphaFold B0BNC9 1-350 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698931
Promoter ID:EPDNEW_R9446
Type:multiple initiation site
Name:Tp53i3_1
Description:tumor protein p53 inducible protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01375,111,765 - 75,111,825EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 75118766 75118767 C T snv SS/JrHsdMcwi (2019), SR/JrHsd (2020), COP/CrCrl (MCW & UW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), ACI/N (MCW), ACI/EurMcwi (RGD), LE/Stm (RGD), LH/MavRrrc (RGD), LN/MavRrrc (RGD), LL/MavRrrc (RGD), SR/JrHsd (RGD), SS/Jr (RGD), SS/JrHsdMcwi (RGD), ACI/EurMcwi (2019), ACI/N (2020), LEXF11/Stm (2020), LEXF3/Stm (2020), LEXF4/Stm (2020), LE/Stm (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), ACI/EurMcwi (MCW)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 80036416 80036417 C T snv ACI/EurMcwi (MCW), LEC/Tj (KyushuU), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), LH/MavRrrc (KNAW), LL/MavRrrc (KNAW), LN/MavRrrc (KNAW), SR/JrHsd (KNAW), SS/Jr (KNAW), SS/JrHsdMcwi (KNAW), ACI/N (KNAW), ACI/EurMcwi (KNAW), LE/Stm (Illumina) (KNAW), LE/Stm (SOLiD) (KNAW), LE/OrlBarth (UDEL), Crl:SD (UDEL), BUF/MNa (KyushuU), NIG-III/Hok (KyushuU), LE/Stm (KyushuU), RCS/Kyo (KyushuU), HWY/Slc (KyushuU), COP/CrCrl (MCW & UW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 72731501 72731502 C T snv ACI/EurMcwi (MCW), LCR/1Mco (UMich), SS/JrHsdMcwi (MCW), SS/JrHsdMcwi (MDC), ACI/N (KNAW), LE/Stm (KNAW), COP/CrCrl (MCW & UW), ACI/EurMcwi (ICL), LE/Stm (ICL), LH/MavRrrc (ICL), LL/MavRrrc (ICL), LN/MavRrrc (ICL), SR/JrHsd (ICL), SS/Jr (ICL), SS/JrHsdMcwi (ICL), HCR/1Mco (UMich), SR/JrHsd (MCW)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 69627785 69627786 C T snv ACI/EurMcwi (2019), ACI/N (2020), LEXF11/Stm (2020), LEXF3/Stm (2020), LEXF4/Stm (2020), SS/JrHsdMcwi (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), SR/JrHsd (2020), LE/Stm (2019)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304982 AgrOrtholog
BioCyc Gene G2FUF-17792 BioCyc
Ensembl Genes ENSRNOG00000005177 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000006924 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000068232.2 UniProtKB/TrEMBL
  ENSRNOP00000079255.1 UniProtKB/TrEMBL
  ENSRNOP00000097423 ENTREZGENE
  ENSRNOP00000097423.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006924 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000076653.3 UniProtKB/TrEMBL
  ENSRNOT00000100806 ENTREZGENE
  ENSRNOT00000100806.1 UniProtKB/TrEMBL
  ENSRNOT00000116185.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7124147 IMAGE-MGC_LOAD
InterPro ADH_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADH_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GroES-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKS_ER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:188074 IMAGE-MGC_LOAD
NCBI Gene 289138 ENTREZGENE
Pfam ADH_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADH_zinc_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cryzl2 PhenoGen
SMART PKS_ER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50129 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A096MJR4_RAT UniProtKB/TrEMBL
  A0A8I5ZMC2_RAT UniProtKB/TrEMBL
  A0A8I6ASM8_RAT UniProtKB/TrEMBL
  B0BNC9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-02-15 Cryzl2  crystallin zeta like 2  Tp53i3  tumor protein p53 inducible protein 3  Name and Symbol changed 629549 APPROVED
2014-07-29 Tp53i3  tumor protein p53 inducible protein 3  RGD1304982  similar to RIKEN cDNA 2810025M15  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1304982  similar to RIKEN cDNA 2810025M15   RGD1304982_predicted  similar to RIKEN cDNA 2810025M15 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1304982_predicted  similar to RIKEN cDNA 2810025M15 (predicted)  LOC289138_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC289138_predicted  similar to RIKEN cDNA 2810025M15 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL