Pm20d1 (peptidase M20 domain containing 1)

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Gene: Pm20d1 (peptidase M20 domain containing 1) Rattus norvegicus

Analyze

Symbol:

Pm20d1

Name:

peptidase M20 domain containing 1

RGD ID:

1564063

Description:

Predicted to have hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Predicted to be involved in several processes, including energy homeostasis; negative regulation of neuron death; and regulation of oxidative phosphorylation uncoupler activity. Predicted to localize to extracellular space. Orthologous to human PM20D1 (peptidase M20 domain containing 1); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

LOC498226; N-fatty-acyl-amino acid synthase/hydrolase PM20D1; probable carboxypeptidase PM20D1; RGD1564063; similar to hypothetical protein FLJ32569

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	43,237,954 - 43,259,999 (+)	NCBI
Rnor_6.0 Ensembl	13	48,575,091 - 48,596,515 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	13	48,575,094 - 48,596,515 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	13	53,650,960 - 53,670,855 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	44,735,202 - 44,755,913 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	13	43,576,159 - 43,597,847 (+)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

17beta-estradiol (EXP)

2,3,7,8-tetrabromodibenzodioxine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

aflatoxin B1 (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP)

carbon nanotube (ISO)

cyclosporin A (ISO)

endosulfan (EXP)

ethanol (ISO)

etoposide (ISO)

furan (EXP)

methapyrilene (ISO)

paracetamol (ISO)

propiconazole (ISO)

sunitinib (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adaptive thermogenesis (ISO)

amide biosynthetic process (IBA,ISO)

cellular amide catabolic process (IBA,ISO)

cellular amino acid metabolic process (IBA,ISO)

cellular lipid metabolic process (IBA,ISO)

energy homeostasis (ISO)

negative regulation of neuron death (ISO)

nitrogen compound metabolic process (IBA)

regulation of oxidative phosphorylation uncoupler activity (ISO)

Cellular Component

extracellular space (ISO)

Molecular Function

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (IBA,ISO)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	RGD automated data pipeline
3.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19056867	PMID:21840748	PMID:27374330

Genomics

Comparative Map Data

Pm20d1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	43,237,954 - 43,259,999 (+)	NCBI
Rnor_6.0 Ensembl	13	48,575,091 - 48,596,515 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	13	48,575,094 - 48,596,515 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	13	53,650,960 - 53,670,855 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	44,735,202 - 44,755,913 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	13	43,576,159 - 43,597,847 (+)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

PM20D1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	1	205,828,025 - 205,850,132 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	1	205,828,025 - 205,850,132 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	1	205,797,153 - 205,819,260 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	204,063,776 - 204,085,868 (-)	NCBI	NCBI36		hg18	NCBI36
Celera	1	178,933,498 - 178,955,670 (-)	NCBI
Cytogenetic Map	1	q32.1	NCBI
HuRef	1	176,961,776 - 176,983,237 (-)	NCBI		HuRef
CHM1_1	1	207,220,641 - 207,242,775 (-)	NCBI		CHM1_1

Pm20d1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	131,725,122 - 131,749,210 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	1	131,725,119 - 131,749,211 (+)	Ensembl
GRCm38	1	131,797,385 - 131,821,472 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	131,797,381 - 131,821,473 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	133,693,972 - 133,714,692 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	1	133,624,944 - 133,649,018 (+)	NCBI			mm8
Celera	1	134,401,882 - 134,422,608 (+)	NCBI		Celera
Cytogenetic Map	1	E4	NCBI

Pm20d1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	41,518,526 - 41,544,348 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	41,522,800 - 41,544,332 (-)	NCBI	ChiLan1.0	ChiLan1.0

PM20D1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	185,720,642 - 185,742,757 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	185,720,642 - 185,742,757 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	1	181,437,045 - 181,459,103 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

PM20D1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	38	2,250,272 - 2,270,653 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	38	2,247,645 - 2,270,286 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Pm20d1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936557	6,610,862 - 6,631,220 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PM20D1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	9	66,522,015 - 66,550,511 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	72,788,453 - 72,816,829 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PM20D1
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	23,498,460 - 23,521,233 (+)	NCBI
ChlSab1.1 Ensembl	25	23,498,845 - 23,520,637 (+)	Ensembl

Pm20d1
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624807	5,406,363 - 5,428,392 (+)	NCBI

Position Markers

RH135125

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	13	48,594,238 - 48,594,440	NCBI	Rnor6.0
Rnor_5.0	13	53,668,578 - 53,668,780	UniSTS	Rnor5.0
RGSC_v3.4	13	44,753,636 - 44,753,838	UniSTS	RGSC3.4
Celera	13	43,595,570 - 43,595,772	UniSTS
RH 3.4 Map	13	111.9	UniSTS
Cytogenetic Map	13	q13	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	107975663	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	107975663	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	107975663	Rat
61339	Bp24	Blood pressure QTL 24		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	9016742	50513953	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	9016906	82995569	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	9016906	82995569	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	12193394	108478121	Rat
9589141	Insul28	Insulin level QTL 28	10.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	13	14096330	59096330	Rat
7411662	Foco29	Food consumption QTL 29	20.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	13	14096330	59096330	Rat
1300163	Cardf1	Cardiac cell morphology QTL 1	4.18		aorta morphology trait (VT:0000272)	artery lesion measurement (CMO:0000975)	13	14441582	50799665	Rat
2302275	Gluco37	Glucose level QTL 37	3.8		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	13	14441582	51577031	Rat
2317040	Aia21	Adjuvant induced arthritis QTL 21	2.75		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	14624631	59624631	Rat
2317046	Aia8	Adjuvant induced arthritis QTL 8	3.9700000286102295		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	14624631	59624631	Rat
631645	Bp121	Blood pressure QTL 121	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	19810814	64810814	Rat
9589164	Gluco66	Glucose level QTL 66	6.67	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	20052477	65052477	Rat
1331784	Bp222	Blood pressure QTL 222	2.944		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	21482481	58537177	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	24502279	108770533	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	28008338	73008338	Rat
70170	Eae14	Experimental allergic encephalomyelitis QTL 14		0.0024	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	28584452	73584452	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	29076934	74076934	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	29076934	74076934	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	35301263	107975663	Rat
2301962	Cm72	Cardiac mass QTL 72	4.12		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	13	36147533	64868393	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	36147533	99968921	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	36147533	99968921	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	36147533	99968921	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	36147533	99968921	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	37346348	82346348	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	39372927	84372927	Rat
10755495	Bp387	Blood pressure QTL 387	3.78		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	39501300	93652524	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	42310744	86833540	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	42310744	87310744	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	42508345	87508345	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	42508345	87508345	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	43575717	88575717	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	45676629	90676629	Rat
2303032	Bp328	Blood pressure QTL 328			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	46444570	50799665	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	264
Count of miRNA genes:	159
Interacting mature miRNAs:	199
Transcripts:	ENSRNOT00000009838
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1		16	16		16				23
Low	2	43	41	25	19	25	8	11	49	12	36	11	8
Below cutoff									25		5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109068	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ210945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000242	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000009838 ⟹ ENSRNOP00000009838

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	13	48,575,091 - 48,596,515 (+)	Ensembl

RefSeq Acc Id:

NM_001109068 ⟹ NP_001102538

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	43,237,971 - 43,259,999 (+)	NCBI
Rnor_6.0	13	48,575,094 - 48,596,515 (+)	NCBI
Rnor_5.0	13	53,650,960 - 53,670,855 (+)	NCBI
RGSC_v3.4	13	44,735,202 - 44,755,913 (+)	RGD
Celera	13	43,576,159 - 43,597,847 (+)	RGD

Sequence:

show sequence

TAAACTCCAGCCTGACTGGCGGCGCGCCATCGGAGAGACATGGCTGAGCTACTTGTTATCTTGC
CCACCCGGGCAGCTGTGCTCCTTCTCTTTTTCGCTACCGTCTCAGGATCCACGGGCCCTGGCAG
CAGGGAAAGTCGAGGATCGTCGCGGATCCCTTCCCAGTTCAGCGAGGAGGAGCGCGTCGCTATG
AAAGAGGCGCTGAAAGGTGCCATCCGGATTCCCACAGTGTCTTTCAGCCACGAGGAATCCAACA
CCACAGCCCTTGCTGAGTTTGGAGAATATATCCGAAAAGCCTTTCCTACAGTGTTCCACAGCAA
CCTTATCCAACACGAAGTCGTGGGGAAGTATAGCCACCTGCTCACCGTCCGAGGCTCGGACCCC
AGTTTGCAGCCCTACATGCTGATGGCTCACTTCGACGTGGTTCCTGCCTCTGAAGAAGGATGGG
AGGTGCCCCCGTTCTCAGGCCTGGAGCAAAATGGCTTCATCCATGGCCGGGGTGCGCTGGACAA
CAAAAACTCTGTGATGGCAGTCCTGCAGGCTTTGGAGCTCCTGTTGATCAGAAAATACAGCCCC
AAAAGACCTTTCTTCATTGCTTTGGGCCATGATGAGGAGGTGTCTGGGACAAAGGGGGCTCAGC
AGATCTCAGCACTCTTACAGACGAGGGGTGTCCAGCTAGCTTTTCTTGTGGATGAAGGGAGCTT
TATCTTGGAAGACTTCATTCCGAACCTCAAGAAGCCGTTTGCCATGATTTCAGTCACCGAGAAG
GGTGCCCTTGACCTCATGCTGCAAGTAAACATGACTCCAGGCCACTCTTCAGCTCCCCCAAAGG
AGACAAGCATTGGAATCCTTTCTGCCGCTGTCAGCCGACTGGAGCAGACACCAATGCCAAACAT
GTTTGGAAACGGGCCATTGAAGAAGACATTGAAGCTACTGGCAAATGAGTTTTCCTTCCCTACC
AATATAATCTTGGGGAACCTGTGGCTATTCCGTCCCATTGTAAGCAGGGTAATGGAGAGGAATC
CCATAACGAATGCATTGGTCAGAACTACCACAGCCCTCACCATGTTCAATGCAGGAATCAAGGT
GAATGTCATCCCCCCATTGGCTCAGGCGACAGTCAACTTCCGAATTCACCCTTCGCAGACAGTA
CACGAGGTCGTAGAACTCGTCCAGAACATTGTGGCTGATGACCGAGTCCAGTTGCATGTGTTGA
GATCCTTTGAACCACTGCCCGTCAGCCCCTCTGATGACCAGGCCATGGGCTACCAGCTGCTTCA
ACAGACCATACAGTCTGTCTTCCCGGAAGTCAAGATCATTGTCCCCGGTATTTGTATTGGCAAC
ACGGACACCCGACACTATGTCAACCTGACCAATGGCTTGTACCGGTTCAACCCCGTTTTCCTGA
AGCCTCAGGACTTCAGTAGTGTCCATGGAATCAATGAGAAAATCTCCGTTGAGAGCTACCAGAA
CCAGGTGAAGTTCATCTTTGAGTTGATCCAAAATGCTGACACCTACAGCAAGCCAGTTCCTCAT
CAGCATGAACTATGAGACAAGGACCCAGCTGGGTGAGGGGCGCCCAGCACTGAGCCAGGACTCA
CCTAAGGGGAGAGGAGCTGGTATTAAGGAAAGGTTTGGTGGAAACCATCCTGTCATGCAGGGTT
CACCTGCCTGGCTCCCTCCTTCACTCACCGAGGAGGAAAGGGAGATGAACATAATCTCACCTGT
CATCCTCCTGACACCTGTGTTCTTCCCATGAGTGGCATCTGCTGCCTGTCCTGCCTGTTGGCCT
GTCTCATGCCGGTGGTTACTAACTATTCCACTTTCCCAGCCTGTCTTAACAAATACAGATTTTG
GGAACACCTCAAGCAGGGTTTAATCTAGAGTATTGACTTCGGATACTTGAGCCGGACTGTCTTC
TAGAATTTCCTTTCTCCTGTCTTCTCTCCAACTTGGGAGCTGCCCCTTGGCCTCTTTCTTCCTG
CCTCTGCTTCCTTCCTCCAATCTCCGGTTCGTTTCCATATCTGCAGTTAGGACTCAAACTGAGA
AGCTCCCGTGATCACAGTCAAATAAAGGGGTCCGTGTAGTGACTGTCAAGCTGGCCTCCGTCAA
GTGAGTGGGAGGTGGAGACTTTGCAAGAAACCCAGAACTCCTAGTTCCAGAGGCTTGGGCTCTT
GGGATTGTTGTTCCCCTCCCCTGCCCTGTTCCTGCCACCTGCTGTTGCTGCCCCACCTCAGGAA
GCTCTAATCTGTGAAAGCATTTCCCTGGCACAGTTTATGGGCTGAGCTCCCAAGAGAGGAACAC
TCAAGATCCAGCTTCTCAGTGGCTCCCTGGCCCTGGCTTGTCCTGTTTCAGAATGACCAAGGGG
AAGTGGAGGGCAAGGAAGGGGATGGTTAGAGGGGCTCTTCCCTGGACAAAAGAAGCAAGCGTCC
ATTAGCGTATATTGGAGCTCTTGTCTTCTCTCTGGACTCCAACCCTACGCATATTTGGATGCAC
TTAGTAGCTGCCAGGTGGGGAGCATTGGAAAGCCACATTTCTTGGCTCAAGGCCACCATCTCTG
CTTTGTGGATGACAAGGGGAGTCAAGGTCACACAGGGAGACACAGAAACGGAGCTTGAAAAGCT
CCCTCTTTTCCCCTCTCCAGACTAGCACCTTCTGTGTCTCCCAGCAGTTTGACAGTTCTAGGTT
TGCTTGCCCCCCACCTCCTTGGAAATCCCCATTCTCCCTCCTCCCAAGTACTTACCTTCCCCCC
AGGATGTGAACTGTTCCTTGAAGCTCTGACTTAATTGTTATCATTAGAAACAGTGTGGGGATTA
TTCGAGCTTTTTAGCTACTCCTGCTAAGATTCACATTCCTTCCTCACTCTGGCTTTTTGGCCAA
CTCAGTACTTATTCAGCCTTAGTTGGAGGGCAAGCTTAAGAACAAAGATAATCCTTTACTTTCG
TGCAGAGCTCTGTGAGATCGTCTTATGCGTGCCTTATCTCAGCCCTCTGAGCATGCTGTCATTA
CCCCTTCCTACAGAGACTGGCTACACATCTTGCTGGAAACAGTTGTCAAACCTTCATTACCTTG
CCATCGGGACCATTCTCTGATCCTGAATCACCTACTCCCCACTGATTTCTTATTTAATTCTCAT
AACTACTGTGGCATGAGTACCCCCACTGTTGTTATGTTGTAAACAAAGTCATACGAGGAAAAGT
ATTCACAGGGAGGGAACATGGCCGACTGGGGCTTGCCTTTGTAGGGTCATTAGGATTAGGCCCT
GGGTCTGAGCTCCATCCTTGACTTATTAATGGACTTTTTAAGAAGAGAGTTTGGGCAAATAGAC
ACATTTAATCTGATTCGGACAAGGCACCATGAATACCTGTGTCAAAACATCACAGTACTCCATC
CACTAAATCAGAGAAAGAGAGGGGGAAAGAGAGCAGAAGACAGACAGGTTCATACATGTACGTC
ATGTGAGGGCCTATACCATCTCTTGCACAAGGAGACCTCTATCCATCAGGGGGCAAACCAGTGC
TCCCCACATGATTTTAACACTCCCGAGCTGTGAGCCGAAATAAACGTCTTTTTTTTTATAACTC
GACCCGGTTTGTGGTGTCATGTTCTTGGAAACAGAAAACAAGAGTAGCACAATTTGAATGCACT
ATCACTCCATTTTGTAAAAAGGAAGTGCCAGGTTTAAAAATCCCAAGGCTGCACAAGACCATGC
CAGTGTTAAGAACAGGGTCTCTCTGAATTCAAAGTCTATGCTACTAGTCCTGAAGAGAAAACAG
ACTCCCAAAAGCCC

hide sequence

RefSeq Acc Id:

XR_005492268

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	43,237,954 - 43,245,164 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102538	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM09816	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001102538 ⟸ NM_001109068

- Peptide Label:

precursor

- Sequence:

show sequence

MAELLVILPTRAAVLLLFFATVSGSTGPGSRESRGSSRIPSQFSEEERVAMKEALKGAIRIPTV
SFSHEESNTTALAEFGEYIRKAFPTVFHSNLIQHEVVGKYSHLLTVRGSDPSLQPYMLMAHFDV
VPASEEGWEVPPFSGLEQNGFIHGRGALDNKNSVMAVLQALELLLIRKYSPKRPFFIALGHDEE
VSGTKGAQQISALLQTRGVQLAFLVDEGSFILEDFIPNLKKPFAMISVTEKGALDLMLQVNMTP
GHSSAPPKETSIGILSAAVSRLEQTPMPNMFGNGPLKKTLKLLANEFSFPTNIILGNLWLFRPI
VSRVMERNPITNALVRTTTALTMFNAGIKVNVIPPLAQATVNFRIHPSQTVHEVVELVQNIVAD
DRVQLHVLRSFEPLPVSPSDDQAMGYQLLQQTIQSVFPEVKIIVPGICIGNTDTRHYVNLTNGL
YRFNPVFLKPQDFSSVHGINEKISVESYQNQVKFIFELIQNADTYSKPVPHQHEL

hide sequence

RefSeq Acc Id:

ENSRNOP00000009838 ⟸ ENSRNOT00000009838

Protein Domains

M20_dimer

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1564063	AgrOrtholog
Ensembl Genes	ENSRNOG00000039745	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000009838	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000009838	ENTREZGENE, UniProtKB/TrEMBL
InterPro	Bact_exopeptidase_dim_dom	UniProtKB/TrEMBL
	Peptidase_M20	UniProtKB/TrEMBL
	Peptidase_M20_dimer	UniProtKB/TrEMBL
NCBI Gene	498226	ENTREZGENE
Pfam	M20_dimer	UniProtKB/TrEMBL
	Peptidase_M20	UniProtKB/TrEMBL
PhenoGen	Pm20d1	PhenoGen
Superfamily-SCOP	Peptidase_M20_dimer	UniProtKB/TrEMBL
UniProt	F1M0Q9_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-05-02	Pm20d1	peptidase M20 domain containing 1	RGD1564063	similar to hypothetical protein FLJ32569	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1564063	similar to hypothetical protein FLJ32569	RGD1564063_predicted	similar to hypothetical protein FLJ32569 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1564063_predicted	similar to hypothetical protein FLJ32569 (predicted)	LOC498226	similar to hypothetical protein FLJ32569	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC498226	similar to hypothetical protein FLJ32569			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar