Rab3gap1 (RAB3 GTPase activating protein catalytic subunit 1) - Rat Genome Database

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Gene: Rab3gap1 (RAB3 GTPase activating protein catalytic subunit 1) Rattus norvegicus
Analyze
Symbol: Rab3gap1
Name: RAB3 GTPase activating protein catalytic subunit 1
RGD ID: 1306487
Description: Enables GTPase activator activity. Predicted to be involved in several processes, including establishment of protein localization to endoplasmic reticulum membrane; modulation of chemical synaptic transmission; and positive regulation of metabolic process. Located in excitatory synapse. Human ortholog(s) of this gene implicated in Warburg micro syndrome 1. Orthologous to human RAB3GAP1 (RAB3 GTPase activating protein catalytic subunit 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; rotenone.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC304759; RAB3 GTPase activating protein subunit 1; RAB3 GTPase-activating protein 130 kDa subunit; rab3 GTPase-activating protein catalytic subunit; Rab3-GAP; rab3-GAP p130; RGD1306487; similar to RAB3 GTPase-activating protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81341,908,179 - 41,981,611 (+)NCBIGRCr8
mRatBN7.21339,355,698 - 39,429,154 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1339,352,247 - 39,429,169 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1341,941,540 - 42,015,466 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01343,229,653 - 43,303,577 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01340,492,442 - 40,565,813 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01344,578,208 - 44,649,876 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1344,615,553 - 44,648,620 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01349,662,265 - 49,734,485 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41340,594,232 - 40,636,723 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1339,730,571 - 39,803,671 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
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Original Reference(s)
Rab3gap1Ratamenorrhea  ISORAB3GAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: AmenorrheaClinVarPMID:25741868 more ...
Rab3gap1Ratcryptorchidism  ISORAB3GAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: CryptorchidismClinVar 
Rab3gap1Ratgenetic disease  ISORAB3GAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:15696165 more ...
Rab3gap1RatMartsolf Syndrome  ISORAB3GAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Martsolf syndromeClinVarPMID:23420520 and PMID:29300443
Rab3gap1RatMartsolf Syndrome 2  ISORAB3GAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Martsolf syndrome 2ClinVarPMID:23420520 more ...
Rab3gap1RatWarburg micro syndrome  ISORAB3GAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Warburg micro syndromeClinVarPMID:25741868 more ...
Rab3gap1RatWarburg micro syndrome 1  ISORAB3GAP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:15216542 more ...
Rab3gap1RatWHIM Syndrome  ISORAB3GAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Warts more ...ClinVarPMID:28492532
Object Symbol
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Original Reference(s)
Rab3gap1RatWarburg micro syndrome  ISORAB3GAP1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Object Symbol
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Original Reference(s)
Rab3gap1RatMartsolf Syndrome 2  ISORAB3GAP1 (Homo sapiens)7240710 OMIM 
Rab3gap1RatWarburg micro syndrome 1  ISORAB3GAP1 (Homo sapiens)7240710 OMIM 

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Original Reference(s)
Rab3gap1Rat(1->4)-beta-D-glucan multiple interactionsISORab3gap1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RAB3GAP1 mRNACTDPMID:36331819
Rab3gap1Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISORAB3GAP1 (Homo sapiens)64804642 more ...CTDPMID:31675489
Rab3gap1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORab3gap1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of RAB3GAP1 mRNACTDPMID:21570461
Rab3gap1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of RAB3GAP1 mRNACTDPMID:32109520
Rab3gap1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORab3gap1 (Mus musculus)6480464[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of RAB3GAP1 mRNACTDPMID:25975270
Rab3gap1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of RAB3GAP1 mRNACTDPMID:21215274
Rab3gap1Rat3,4-methylenedioxymethamphetamine decreases expressionISORab3gap1 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of RAB3GAP1 mRNACTDPMID:26251327
Rab3gap1Rat4,4'-sulfonyldiphenol increases expressionISORab3gap1 (Mus musculus)6480464bisphenol S results in increased expression of RAB3GAP1 mRNACTDPMID:39298647
Rab3gap1Ratall-trans-retinoic acid decreases expressionISORAB3GAP1 (Homo sapiens)6480464Tretinoin results in decreased expression of RAB3GAP1 mRNACTDPMID:15498508
Rab3gap1Ratantirheumatic drug increases expressionISORAB3GAP1 (Homo sapiens)6480464Antirheumatic Agents results in increased expression of RAB3GAP1 mRNACTDPMID:24449571
Rab3gap1Rataristolochic acid A decreases expressionISORAB3GAP1 (Homo sapiens)6480464aristolochic acid I results in decreased expression of RAB3GAP1 mRNACTDPMID:33212167
Rab3gap1RatAroclor 1254 decreases expressionISORab3gap1 (Mus musculus)6480464Chlorodiphenyl (54% Chlorine) results in decreased expression of RAB3GAP1 mRNACTDPMID:23650126
Rab3gap1Ratarsenite(3-) multiple interactionsISORAB3GAP1 (Homo sapiens)6480464arsenite inhibits the reaction [G3BP1 protein binds to RAB3GAP1 mRNA]CTDPMID:32406909
Rab3gap1Ratbenzo[a]pyrene diol epoxide I increases expressionISORAB3GAP1 (Homo sapiens)64804647 more ...CTDPMID:26238291
Rab3gap1Ratbisphenol A decreases expressionISORAB3GAP1 (Homo sapiens)6480464bisphenol A results in decreased expression of RAB3GAP1 mRNACTDPMID:25047013
Rab3gap1Ratbisphenol A increases expressionISORAB3GAP1 (Homo sapiens)6480464bisphenol A results in increased expression of RAB3GAP1 mRNACTDPMID:36232920
Rab3gap1Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of RAB3GAP1 mRNACTDPMID:34947998
Rab3gap1Ratbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of RAB3GAP1 mRNACTDPMID:25181051
Rab3gap1Ratbisphenol AF increases expressionISORAB3GAP1 (Homo sapiens)6480464bisphenol AF results in increased expression of RAB3GAP1 proteinCTDPMID:34186270
Rab3gap1RatBisphenol B increases expressionISORAB3GAP1 (Homo sapiens)6480464bisphenol B results in increased expression of RAB3GAP1 proteinCTDPMID:34186270

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Biological Process
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Original Reference(s)
Rab3gap1Ratbrain development involved_inISORAB3GAP1 (Homo sapiens)1624291 PMID:20512159RGDPMID:20512159
Rab3gap1Ratbrain development involved_inIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3gap1Ratbrain development involved_inIBAPANTHER:PTN002725276 and UniProtKB:Q150421600115GO_REF:0000033GO_CentralGO_REF:0000033
Rab3gap1Ratcamera-type eye development involved_inIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3gap1Ratcamera-type eye development involved_inISORAB3GAP1 (Homo sapiens)1624291 PMID:20512159RGDPMID:20512159
Rab3gap1Ratestablishment of protein localization to endoplasmic reticulum membrane involved_inISSUniProtKB:Q150421600115GO_REF:0000024ParkinsonsUK-UCLGO_REF:0000024
Rab3gap1Ratestablishment of protein localization to endoplasmic reticulum membrane involved_inISORAB3GAP1 (Homo sapiens)1624291 PMID:24891604RGDPMID:24891604
Rab3gap1Ratestablishment of protein localization to endoplasmic reticulum membrane involved_inIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3gap1Ratexcitatory postsynaptic potential involved_inISORab3gap1 (Mus musculus)1624291 PMID:16782817RGDPMID:16782817
Rab3gap1Ratexcitatory postsynaptic potential involved_inISSUniProtKB:Q80UJ71600115GO_REF:0000024ParkinsonsUK-UCLGO_REF:0000024
Rab3gap1Ratface morphogenesis involved_inISORAB3GAP1 (Homo sapiens)1624291 PMID:20512159RGDPMID:20512159
Rab3gap1Ratface morphogenesis involved_inIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3gap1Rathypothalamus development involved_inIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3gap1Rathypothalamus development involved_inISORAB3GAP1 (Homo sapiens)1624291 PMID:20512159RGDPMID:20512159
Rab3gap1Ratlipid droplet organization acts_upstream_of_or_withinISORAB3GAP1 (Homo sapiens)1624291 PMID:24239381RGDPMID:24239381
Rab3gap1Ratlipid droplet organization acts_upstream_of_or_withinIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3gap1Ratlipid droplet organization involved_inISSUniProtKB:Q150421600115GO_REF:0000024ParkinsonsUK-UCLGO_REF:0000024
Rab3gap1Ratpositive regulation of autophagosome assembly involved_inISORAB3GAP1 (Homo sapiens)1624291 PMID:25495476RGDPMID:25495476
Rab3gap1Ratpositive regulation of autophagosome assembly involved_inIBAPANTHER:PTN000484253 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rab3gap1Ratpositive regulation of autophagosome assembly involved_inIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
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Original Reference(s)
Rab3gap1Ratcis-Golgi network located_inISSUniProtKB:Q150421600115GO_REF:0000024UniProtGO_REF:0000024
Rab3gap1Ratcis-Golgi network located_inIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3gap1Ratcis-Golgi network located_inISORAB3GAP1 (Homo sapiens)1624291 PMID:26063829RGDPMID:26063829
Rab3gap1Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Rab3gap1Ratcytoplasm located_inISSUniProtKB:Q150421600115GO_REF:0000024ParkinsonsUK-UCLGO_REF:0000024
Rab3gap1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Rab3gap1Ratendoplasmic reticulum located_inIEAUniProtKB-SubCell:SL-00951600115GO_REF:0000044UniProtGO_REF:0000044
Rab3gap1Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Rab3gap1Ratendoplasmic reticulum tubular network located_inISSUniProtKB:Q150421600115GO_REF:0000024ParkinsonsUK-UCLGO_REF:0000024
Rab3gap1Ratendoplasmic reticulum tubular network located_inISORAB3GAP1 (Homo sapiens)1624291 PMID:24891604RGDPMID:24891604
Rab3gap1Ratendoplasmic reticulum tubular network located_inIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3gap1Ratexcitatory synapse located_inIDA 8554379PMID:19730411BHF-UCL 
Rab3gap1RatGolgi apparatus located_inIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3gap1RatGolgi apparatus located_inIEAUniProtKB-SubCell:SL-01321600115GO_REF:0000044UniProtGO_REF:0000044
Rab3gap1RatGolgi apparatus located_inISORAB3GAP1 (Homo sapiens)1624291 PMID:25495476RGDPMID:25495476
Rab3gap1Ratlipid droplet located_inIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3gap1Ratlipid droplet located_inISORAB3GAP1 (Homo sapiens)1624291 PMID:25495476RGDPMID:25495476
Rab3gap1Ratpostsynapse located_inIEAGO:00600791600115GO_REF:0000108GOCGO_REF:0000108
Rab3gap1Ratprotein-containing complex part_ofISSUniProtKB:Q150421600115GO_REF:0000024ParkinsonsUK-UCLGO_REF:0000024
Rab3gap1Ratprotein-containing complex part_ofISORAB3GAP1 (Homo sapiens)1624291 PMID:24891604RGDPMID:24891604
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Molecular Function
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Original Reference(s)
Rab3gap1RatGTPase activator activity enablesISORAB3GAP1 (Homo sapiens)1624291 PMID:10859313 more ...RGDPMID:10859313 more ...
Rab3gap1RatGTPase activator activity enablesIBAPANTHER:PTN000484253 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rab3gap1RatGTPase activator activity enablesIEAInterPro:IPR0457001600115GO_REF:0000002InterProGO_REF:0000002
Rab3gap1RatGTPase activator activity enablesIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3gap1RatGTPase activator activity enablesIEAUniProtKB-KW:KW-03431600115GO_REF:0000043UniProtGO_REF:0000043
Rab3gap1RatGTPase activator activity enablesIDA 8553935PMID:9733780UniProt 
Rab3gap1Ratguanyl-nucleotide exchange factor activity contributes_toISORAB3GAP1 (Homo sapiens)1624291 PMID:24891604RGDPMID:24891604
Rab3gap1Ratguanyl-nucleotide exchange factor activity enablesISORAB3GAP1 (Homo sapiens)1624291 PMID:26063829RGDPMID:26063829
Rab3gap1Ratguanyl-nucleotide exchange factor activity enablesISSUniProtKB:Q150421600115GO_REF:0000024UniProtGO_REF:0000024
Rab3gap1Ratguanyl-nucleotide exchange factor activity enablesIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
Rab3gap1Ratprotein binding enablesIPIUniProtKB:Q5U1Z08553935PMID:9733780UniProt 
Rab3gap1Ratprotein binding enablesISORAB3GAP1 (Homo sapiens)1624291UniProtKB:P49257 more ...RGDPMID:22337587
Rab3gap1Ratsmall GTPase binding enablesISSUniProtKB:Q150421600115GO_REF:0000024ParkinsonsUK-UCLGO_REF:0000024
Rab3gap1Ratsmall GTPase binding enablesISORAB3GAP1 (Homo sapiens)1624291UniProtKB:P20336 more ...RGDPMID:10859313 and PMID:24891604
Rab3gap1Ratsmall GTPase binding enablesIEAUniProtKB:Q15042 and ensembl:ENSP000002641581600115GO_REF:0000107EnsemblGO_REF:0000107
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation. Ko J, etal., EMBO J. 2009 Oct 21;28(20):3244-55. doi: 10.1038/emboj.2009.249. Epub 2009 Sep 3.
3. Molecular cloning and characterization of the noncatalytic subunit of the Rab3 subfamily-specific GTPase-activating protein. Nagano F, etal., J Biol Chem. 1998 Sep 18;273(38):24781-5.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:9030515   PMID:10859313   PMID:11809763   PMID:15057822   PMID:16782817   PMID:16923123   PMID:19056867   PMID:20512159   PMID:24239381   PMID:24891604   PMID:25495476  



Rab3gap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81341,908,179 - 41,981,611 (+)NCBIGRCr8
mRatBN7.21339,355,698 - 39,429,154 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1339,352,247 - 39,429,169 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1341,941,540 - 42,015,466 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01343,229,653 - 43,303,577 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01340,492,442 - 40,565,813 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01344,578,208 - 44,649,876 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1344,615,553 - 44,648,620 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01349,662,265 - 49,734,485 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41340,594,232 - 40,636,723 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1339,730,571 - 39,803,671 (+)NCBICelera
Cytogenetic Map13q13NCBI
RAB3GAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382135,052,292 - 135,176,396 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2135,052,289 - 135,176,667 (+)EnsemblGRCh38hg38GRCh38
GRCh372135,809,862 - 135,928,280 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362135,526,323 - 135,644,029 (+)NCBINCBI36Build 36hg18NCBI36
Celera2129,522,764 - 129,641,200 (+)NCBICelera
Cytogenetic Map2q21.3NCBI
HuRef2127,801,500 - 127,920,838 (+)NCBIHuRef
CHM1_12135,814,735 - 135,933,197 (+)NCBICHM1_1
T2T-CHM13v2.02135,492,756 - 135,617,244 (+)NCBIT2T-CHM13v2.0
Rab3gap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391127,796,492 - 127,871,612 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1127,796,510 - 127,871,605 (+)EnsemblGRCm39 Ensembl
GRCm381127,868,755 - 127,943,876 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1127,868,773 - 127,943,868 (+)EnsemblGRCm38mm10GRCm38
MGSCv371129,765,350 - 129,840,453 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361129,696,338 - 129,771,414 (+)NCBIMGSCv36mm8
Celera1130,509,898 - 130,572,512 (+)NCBICelera
Cytogenetic Map1E3NCBI
cM Map155.8NCBI
Rab3gap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554402,550,982 - 2,646,331 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554402,551,015 - 2,645,938 (+)NCBIChiLan1.0ChiLan1.0
RAB3GAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21339,761,351 - 39,879,611 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B39,776,321 - 39,894,945 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B24,692,363 - 24,810,685 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B139,125,374 - 139,248,010 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B139,125,375 - 139,242,721 (+)Ensemblpanpan1.1panPan2
RAB3GAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11937,861,844 - 38,006,433 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1937,861,804 - 37,963,501 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1938,101,848 - 38,250,489 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01939,307,155 - 39,452,060 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1939,307,185 - 39,409,083 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11937,949,574 - 38,094,207 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01938,110,488 - 38,255,025 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01939,345,841 - 39,490,314 (+)NCBIUU_Cfam_GSD_1.0
Rab3gap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303100,889,929 - 100,975,780 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646940,641,928 - 40,727,837 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646940,642,240 - 40,727,831 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB3GAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1516,763,990 - 16,816,754 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11516,756,368 - 16,893,148 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21519,210,946 - 19,269,571 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAB3GAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11019,295,294 - 19,401,595 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1019,295,351 - 19,402,212 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660613,097,933 - 3,204,848 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab3gap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473234,450,630 - 34,593,675 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473234,450,616 - 34,593,675 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Rab3gap1
444 total Variants

Predicted Target Of
Summary Value
Count of predictions:179
Count of miRNA genes:122
Interacting mature miRNAs:157
Transcripts:ENSRNOT00000005289
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 34 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131192944945417941Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2303030Bp327Blood pressure QTL 327arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133039535141184251Rat

1 to 10 of 34 rows
D13Hmgc85  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01344,588,357 - 44,588,509NCBIRnor6.0
Celera1339,740,890 - 39,741,040UniSTS
Cytogenetic Map13q12UniSTS
AI013755  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21339,428,984 - 39,429,095 (+)MAPPERmRatBN7.2
Rnor_6.01344,649,707 - 44,649,817NCBIRnor6.0
Rnor_5.01349,734,316 - 49,734,426UniSTSRnor5.0
RGSC_v3.41340,636,553 - 40,636,663UniSTSRGSC3.4
Celera1339,803,502 - 39,803,612UniSTS
RH 3.4 Map1393.0UniSTS
Cytogenetic Map13q12UniSTS
BF398383  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21339,426,328 - 39,426,486 (+)MAPPERmRatBN7.2
Rnor_6.01344,647,051 - 44,647,208NCBIRnor6.0
Rnor_5.01349,731,660 - 49,731,817UniSTSRnor5.0
RGSC_v3.41340,633,897 - 40,634,054UniSTSRGSC3.4
Celera1339,800,846 - 39,801,003UniSTS
RH 3.4 Map1393.8UniSTS
Cytogenetic Map13q12UniSTS
UniSTS:234205  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21339,428,531 - 39,428,741 (+)MAPPERmRatBN7.2
Rnor_6.01344,649,254 - 44,649,463NCBIRnor6.0
Rnor_5.01349,733,863 - 49,734,072UniSTSRnor5.0
RGSC_v3.41340,636,100 - 40,636,309UniSTSRGSC3.4
Celera1339,803,049 - 39,803,258UniSTS
Cytogenetic Map13q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000005289   ⟹   ENSRNOP00000005289
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1339,355,734 - 39,429,169 (+)Ensembl
Rnor_6.0 Ensembl1344,615,553 - 44,648,620 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082439   ⟹   ENSRNOP00000070191
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1339,360,383 - 39,429,153 (+)Ensembl
Rnor_6.0 Ensembl1344,615,553 - 44,648,620 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101602   ⟹   ENSRNOP00000087169
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1339,352,247 - 39,429,153 (+)Ensembl
RefSeq Acc Id: NM_001402216   ⟹   NP_001389145
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81341,908,217 - 41,981,611 (+)NCBI
mRatBN7.21339,355,754 - 39,429,154 (+)NCBI
RefSeq Acc Id: NM_001402314   ⟹   NP_001389243
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81341,908,217 - 41,981,611 (+)NCBI
mRatBN7.21339,355,754 - 39,429,154 (+)NCBI
RefSeq Acc Id: XR_005492430
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81341,908,179 - 41,976,134 (+)NCBI
mRatBN7.21339,355,698 - 39,429,154 (+)NCBI
Protein RefSeqs NP_001389145 (Get FASTA)   NCBI Sequence Viewer  
  NP_001389243 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005289
  ENSRNOP00000087169
GenBank Protein P69735 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000070191   ⟸   ENSRNOT00000082439
Ensembl Acc Id: ENSRNOP00000005289   ⟸   ENSRNOT00000005289
Ensembl Acc Id: ENSRNOP00000087169   ⟸   ENSRNOT00000101602
RefSeq Acc Id: NP_001389243   ⟸   NM_001402314
- Peptide Label: isoform 1
- UniProtKB: F1LP59 (UniProtKB/TrEMBL),   A0A8I6A7Y5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001389145   ⟸   NM_001402216
- Peptide Label: isoform 2
- UniProtKB: A0A8I6A7Y5 (UniProtKB/TrEMBL)
Rab3GAP catalytic subunit C-terminal   Rab3GAP catalytic subunit conserved

Name Modeler Protein Id AA Range Protein Structure
AF-P69735-F1-model_v2 AlphaFold P69735 1-775 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 18 of 18 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-18427 BioCyc
Ensembl Genes ENSRNOG00000003953 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000005289 ENTREZGENE
  ENSRNOT00000101602 ENTREZGENE
InterPro Rab3-GAP_cat_su UniProtKB/Swiss-Prot
  Rab3GAP1 UniProtKB/Swiss-Prot
  Rab3GAP1_C UniProtKB/Swiss-Prot
NCBI Gene Rab3gap1 ENTREZGENE
PANTHER PTHR21422 UniProtKB/Swiss-Prot
  RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT UniProtKB/Swiss-Prot
Pfam Rab3-GAP_cat_C UniProtKB/Swiss-Prot
  Rab3-GTPase_cat UniProtKB/Swiss-Prot
PhenoGen Rab3gap1 PhenoGen
RatGTEx ENSRNOG00000003953 RatGTEx
UniProt A0A0G2JXA1_RAT UniProtKB/TrEMBL
  A0A8I6A7Y5 ENTREZGENE, UniProtKB/TrEMBL
  F1LP59 ENTREZGENE, UniProtKB/TrEMBL
  P69735 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 18 of 18 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-24 Rab3gap1  RAB3 GTPase activating protein catalytic subunit 1  Rab3gap1  RAB3 GTPase activating protein subunit 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-12-04 Rab3gap1  RAB3 GTPase activating protein subunit 1  Rab3gap1  RAB3 GTPase activating protein subunit 1  Type changed (type changed from [predicted-high] to [protein-coding]) 629549 APPROVED
2014-08-14 Rab3gap1  RAB3 GTPase activating protein subunit 1  RGD1306487  similar to RAB3 GTPase-activating protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1306487  similar to RAB3 GTPase-activating protein   RGD1306487_predicted  similar to RAB3 GTPase-activating protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1306487_predicted  similar to RAB3 GTPase-activating protein (predicted)  LOC304759_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC304759_predicted  similar to RAB3 GTPase-activating protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL