RAB3GAP1 (RAB3 GTPase activating protein catalytic subunit 1) - Rat Genome Database

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Gene: RAB3GAP1 (RAB3 GTPase activating protein catalytic subunit 1) Chlorocebus sabaeus
Analyze
Symbol: RAB3GAP1
Name: RAB3 GTPase activating protein catalytic subunit 1
RGD ID: 18493050
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN excitatory postsynaptic potential (ortholog); lipid droplet organization (ortholog); positive regulation of gene expression (ortholog); ASSOCIATED WITH amenorrhea (ortholog); cryptorchidism (ortholog); genetic disease (ortholog); FOUND IN excitatory synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rab3 GTPase-activating protein catalytic subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11019,295,294 - 19,401,595 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1019,295,351 - 19,402,212 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660613,097,933 - 3,204,848 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
RAB3GAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11019,295,294 - 19,401,595 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1019,295,351 - 19,402,212 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660613,097,933 - 3,204,848 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RAB3GAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382135,052,292 - 135,176,396 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2135,052,289 - 135,176,667 (+)EnsemblGRCh38hg38GRCh38
GRCh372135,809,862 - 135,928,280 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362135,526,323 - 135,644,029 (+)NCBINCBI36Build 36hg18NCBI36
Celera2129,522,764 - 129,641,200 (+)NCBICelera
Cytogenetic Map2q21.3NCBI
HuRef2127,801,500 - 127,920,838 (+)NCBIHuRef
CHM1_12135,814,735 - 135,933,197 (+)NCBICHM1_1
T2T-CHM13v2.02135,492,756 - 135,617,244 (+)NCBIT2T-CHM13v2.0
Rab3gap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391127,796,492 - 127,871,612 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1127,796,510 - 127,871,605 (+)EnsemblGRCm39 Ensembl
GRCm381127,868,755 - 127,943,876 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1127,868,773 - 127,943,868 (+)EnsemblGRCm38mm10GRCm38
MGSCv371129,765,350 - 129,840,453 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361129,696,338 - 129,771,414 (+)NCBIMGSCv36mm8
Celera1130,509,898 - 130,572,512 (+)NCBICelera
Cytogenetic Map1E3NCBI
cM Map155.8NCBI
Rab3gap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81341,908,179 - 41,981,611 (+)NCBIGRCr8
mRatBN7.21339,355,698 - 39,429,154 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1339,352,247 - 39,429,169 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1341,941,540 - 42,015,466 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01343,229,653 - 43,303,577 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01340,492,442 - 40,565,813 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01344,578,208 - 44,649,876 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1344,615,553 - 44,648,620 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01349,662,265 - 49,734,485 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41340,594,232 - 40,636,723 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1339,730,571 - 39,803,671 (+)NCBICelera
Cytogenetic Map13q13NCBI
Rab3gap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554402,550,982 - 2,646,331 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554402,551,015 - 2,645,938 (+)NCBIChiLan1.0ChiLan1.0
RAB3GAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21339,761,351 - 39,879,611 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B39,776,321 - 39,894,945 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B24,692,363 - 24,810,685 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B139,125,374 - 139,248,010 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B139,125,375 - 139,242,721 (+)Ensemblpanpan1.1panPan2
RAB3GAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11937,861,844 - 38,006,433 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1937,861,804 - 37,963,501 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1938,101,848 - 38,250,489 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01939,307,155 - 39,452,060 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1939,307,185 - 39,409,083 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11937,949,574 - 38,094,207 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01938,110,488 - 38,255,025 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01939,345,841 - 39,490,314 (+)NCBIUU_Cfam_GSD_1.0
Rab3gap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303100,889,929 - 100,975,780 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646940,641,928 - 40,727,837 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646940,642,240 - 40,727,831 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB3GAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1516,763,990 - 16,816,754 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11516,756,368 - 16,893,148 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21519,210,946 - 19,269,571 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Rab3gap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473234,450,630 - 34,593,675 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473234,450,616 - 34,593,675 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 11 60
Low 9
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000014469   ⟹   ENSCSAP00000012441
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1019,295,351 - 19,402,212 (+)Ensembl
RefSeq Acc Id: XM_007964816   ⟹   XP_007963007
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11019,295,294 - 19,401,595 (+)NCBI
Vero_WHO_p1.0NW_0236660613,097,933 - 3,204,848 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007964817   ⟹   XP_007963008
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11019,295,295 - 19,401,595 (+)NCBI
Vero_WHO_p1.0NW_0236660613,097,933 - 3,204,846 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007964818   ⟹   XP_007963009
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11019,295,350 - 19,401,595 (+)NCBI
Vero_WHO_p1.0NW_0236660613,097,933 - 3,204,824 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007963007 (Get FASTA)   NCBI Sequence Viewer  
  XP_007963008 (Get FASTA)   NCBI Sequence Viewer  
  XP_007963009 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012441
  ENSCSAP00000012441.1
Reference Protein Sequences
RefSeq Acc Id: XP_007963007   ⟸   XM_007964816
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RV02 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007963008   ⟸   XM_007964817
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007963009   ⟸   XM_007964818
- Peptide Label: isoform X3
RefSeq Acc Id: ENSCSAP00000012441   ⟸   ENSCSAT00000014469


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016378 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014469.1 UniProtKB/TrEMBL
InterPro Rab3-GAP_cat_su UniProtKB/TrEMBL
  Rab3GAP1 UniProtKB/TrEMBL
  Rab3GAP1_C UniProtKB/TrEMBL
KEGG Report csab:103216981 UniProtKB/TrEMBL
NCBI Gene RAB3GAP1 ENTREZGENE
PANTHER PTHR21422 UniProtKB/TrEMBL
  RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT UniProtKB/TrEMBL
Pfam Rab3-GAP_cat_C UniProtKB/TrEMBL
  Rab3-GTPase_cat UniProtKB/TrEMBL
UniProt A0A0D9RV02 ENTREZGENE, UniProtKB/TrEMBL