Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Il10 (interleukin 10) Rattus norvegicus
Symbol: Il10
Name: interleukin 10
Description: Exhibits interleukin-10 receptor binding activity. Involved in several processes, including cellular response to estradiol stimulus; liver regeneration; and negative regulation of cellular biosynthetic process. Localizes to extracellular space. Used to study several diseases, including lung disease (multiple); perinatal necrotizing enterocolitis; sciatic neuropathy; toxic encephalopathy; and transient cerebral ischemia. Biomarker of several diseases, including decubitus ulcer; lung disease (multiple); obstructive sleep apnea; postpartum depression; and sciatic neuropathy. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune hypersensitivity disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Orthologous to human IL10 (interleukin 10); PARTICIPATES IN Interleukin-10 signaling pathway; interleukin-4 signaling pathway; allograft rejection pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; (-)-epigallocatechin 3-gallate.
Type: protein-coding
Also known as: CSIF; cytokine synthesis inhibitory factor; IL-10; IL10X; interleukin-10
Homo sapiens (human) : IL10 (interleukin 10)  HGNC  Alliance
Mus musculus (house mouse) : Il10 (interleukin 10)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il10 (interleukin 10)
Pan paniscus (bonobo/pygmy chimpanzee) : IL10 (interleukin 10)
Canis lupus familiaris (dog) : IL10 (interleukin 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il10 (interleukin 10)
Sus scrofa (pig) : IL10 (interleukin 10)
Chlorocebus sabaeus (African green monkey) : IL10 (interleukin 10)
Heterocephalus glaber (naked mole-rat) : Il10 (interleukin 10)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01347,738,933 - 47,743,392 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1347,739,526 - 47,743,392 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01352,824,594 - 52,828,560 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41343,953,900 - 43,957,766 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11343,967,906 - 43,972,374 (+)NCBI
Celera1342,821,569 - 42,825,416 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated