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Gene: Slc41a1 (solute carrier family 41 member 1) Rattus norvegicus

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Symbol:

Slc41a1

Name:

solute carrier family 41 member 1

RGD ID:

1311397

Description:

Predicted to enable magnesium:sodium antiporter activity. Predicted to be involved in cellular response to magnesium ion; intracellular magnesium ion homeostasis; and magnesium ion transmembrane transport. Predicted to be located in basolateral plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in nephronophthisis. Orthologous to human SLC41A1 (solute carrier family 41 member 1); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC363985; solute carrier family 41 (magnesium transporter), member 1; solute carrier family 41, member 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC41A1 (solute carrier family 41 member 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Slc41a1 (solute carrier family 41, member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc41a1 (solute carrier family 41 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC41A1 (solute carrier family 41 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC41A1 (solute carrier family 41 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc41a1 (solute carrier family 41 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC41A1 (solute carrier family 41 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC41A1 (solute carrier family 41 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc41a1 (solute carrier family 41 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SLC41A1 (solute carrier family 41 member 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Slc41a1 (solute carrier family 41, member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	slc41a1 (solute carrier family 41 member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	K07H8.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG33181	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ZK185.2	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	slc41a3	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	45,822,999 - 45,843,364 (+)	NCBI		GRCr8
mRatBN7.2	13	43,270,792 - 43,291,162 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	43,270,792 - 43,291,162 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	45,874,200 - 45,894,572 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	47,162,346 - 47,182,718 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	44,427,031 - 44,447,368 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	48,607,308 - 48,627,999 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	48,607,308 - 48,627,999 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	53,681,648 - 53,701,895 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	44,766,706 - 44,777,526 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	44,783,241 - 44,791,595 (+)	NCBI
Celera	13	43,608,641 - 43,629,021 (+)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

familial adult myoclonic epilepsy 5 (ISO)

gastrointestinal stromal tumor (ISO)

Hypokalemic Periodic Paralysis, Type 1 (ISO)

Nephronophthisis-like Nephropathy 2 (ISO)

parathyroid carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4-amino-2,6-dinitrotoluene (EXP)

4-hydroxyphenyl retinamide (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

calcitriol (ISO)

cisplatin (ISO)

Cuprizon (EXP)

dibutyl phthalate (EXP)

diclofenac (ISO)

diethylstilbestrol (ISO)

doxorubicin (ISO)

ethanol (ISO)

lead(0) (ISO)

orphenadrine (EXP)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

testosterone (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

triclosan (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to magnesium ion (ISO,ISS)

intracellular magnesium ion homeostasis (ISO)

magnesium ion transmembrane transport (ISO,ISS)

magnesium ion transport (ISO)

metal ion transport (ISO,ISS)

sodium ion transmembrane transport (IEA)

Cellular Component

basolateral plasma membrane (ISO)

plasma membrane (IBA,ISO)

protein-containing complex (ISO)

Molecular Function

inorganic cation transmembrane transporter activity (ISO,ISS)

magnesium ion transmembrane transporter activity (ISO)

magnesium:sodium antiporter activity (ISO)

protein binding (ISO)

transmembrane transporter activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15713785	PMID:18367447	PMID:21696366	PMID:22031603	PMID:23661805	PMID:23976986	PMID:25263961	PMID:30172737

Genomics

Comparative Map Data

Slc41a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	45,822,999 - 45,843,364 (+)	NCBI		GRCr8
mRatBN7.2	13	43,270,792 - 43,291,162 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	43,270,792 - 43,291,162 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	45,874,200 - 45,894,572 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	47,162,346 - 47,182,718 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	44,427,031 - 44,447,368 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	48,607,308 - 48,627,999 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	48,607,308 - 48,627,999 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	53,681,648 - 53,701,895 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	44,766,706 - 44,777,526 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	44,783,241 - 44,791,595 (+)	NCBI
Celera	13	43,608,641 - 43,629,021 (+)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

SLC41A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	205,789,095 - 205,813,198 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	205,789,094 - 205,813,748 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	205,758,223 - 205,782,326 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	204,024,844 - 204,048,784 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	202,489,878 - 202,513,818	NCBI
Celera	1	178,894,473 - 178,918,404 (-)	NCBI		Celera
Cytogenetic Map	1	q32.1	NCBI
HuRef	1	176,922,911 - 176,946,834 (-)	NCBI		HuRef
CHM1_1	1	207,181,729 - 207,205,652 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	205,053,767 - 205,077,853 (-)	NCBI		T2T-CHM13v2.0

Slc41a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	131,755,236 - 131,776,601 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	131,755,231 - 131,776,603 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	131,828,012 - 131,848,863 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	131,827,493 - 131,848,865 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	133,724,589 - 133,745,440 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	133,655,523 - 133,676,409 (+)	NCBI		MGSCv36	mm8
Celera	1	134,432,506 - 134,453,353 (+)	NCBI		Celera
Cytogenetic Map	1	E4	NCBI
cM Map	1	57.2	NCBI

Slc41a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	41,481,831 - 41,502,992 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	41,481,831 - 41,502,992 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC41A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	43,555,805 - 43,580,543 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	43,519,795 - 43,545,902 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	181,398,145 - 181,422,830 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	185,681,822 - 185,706,424 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	185,681,822 - 185,705,844 (-)	Ensembl	panpan1.1		panPan2

SLC41A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	2,216,378 - 2,239,303 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	2,218,706 - 2,236,672 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	2,309,253 - 2,332,189 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	2,213,651 - 2,236,582 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	2,213,653 - 2,235,882 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	2,209,583 - 2,230,157 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	2,599,591 - 2,622,513 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	2,800,021 - 2,822,961 (-)	NCBI		UU_Cfam_GSD_1.0

Slc41a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	69,400,750 - 69,421,846 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936557	6,640,813 - 6,662,699 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936557	6,640,197 - 6,662,128 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC41A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	66,473,341 - 66,499,805 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	66,473,369 - 66,500,367 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	72,739,718 - 72,766,654 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC41A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	23,536,187 - 23,560,182 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	23,535,263 - 23,560,174 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	24,230,986 - 24,255,631 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc41a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624807	5,445,121 - 5,466,095 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624807	5,445,111 - 5,465,844 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	807
Count of miRNA genes:	301
Interacting mature miRNAs:	373
Transcripts:	ENSRNOT00000063882
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9589141	Insul28	Insulin level QTL 28	10.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	13	11866254	56866254	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	24853925	69853925	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	39968211	83286298	Rat
1300163	Cardf1	Cardiac cell morphology QTL 1	4.18		aorta morphology trait (VT:0000272)	artery lesion measurement (CMO:0000975)	13	12448421	47969993	Rat
2317040	Aia21	Adjuvant induced arthritis QTL 21	2.75		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	12384320	57384320	Rat
631645	Bp121	Blood pressure QTL 121	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	17468282	62468282	Rat
2317046	Aia8	Adjuvant induced arthritis QTL 8	3.9700000286102295		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	12384320	57384320	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	7421791	87286911	Rat
61339	Bp24	Blood pressure QTL 24		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	6002008	47359539	Rat
2303032	Bp328	Blood pressure QTL 328			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	43736327	47969993	Rat
1331784	Bp222	Blood pressure QTL 222	2.944		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	24335432	55601132	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37087983	82087983	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	40983585	85983585	Rat
2302275	Gluco37	Glucose level QTL 37	3.8		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	13	12448421	48744906	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	26244808	71244808	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	33794096	78794096	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	34834947	79834947	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
2301962	Cm72	Cardiac mass QTL 72	4.12		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	13	33794096	60914504	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	39814726	84814726	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	39968211	84968211	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	26244808	71244808	Rat
11530006	Niddm72	Non-insulin dependent diabetes mellitus QTL 72		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	38286298	83286298	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
9589164	Gluco66	Glucose level QTL 66	6.67	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	17711336	62711336	Rat
7411662	Foco29	Food consumption QTL 29	20.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	13	11866254	56866254	Rat

Markers in Region

RH129649

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	43,290,934 - 43,291,115 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	48,627,772 - 48,627,952	NCBI	Rnor6.0
Rnor_5.0	13	53,701,668 - 53,701,848	UniSTS	Rnor5.0
Celera	13	43,628,794 - 43,628,974	UniSTS
RH 3.4 Map	13	111.8	UniSTS
Cytogenetic Map	13	q13	UniSTS

RH142377

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	43,290,765 - 43,290,948 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	48,627,603 - 48,627,785	NCBI	Rnor6.0
Rnor_5.0	13	53,701,499 - 53,701,681	UniSTS	Rnor5.0
Celera	13	43,628,625 - 43,628,807	UniSTS
Cytogenetic Map	13	q13	UniSTS

RH134782

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	43,277,977 - 43,278,158 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	48,614,494 - 48,614,674	NCBI	Rnor6.0
Rnor_5.0	13	53,688,834 - 53,689,014	UniSTS	Rnor5.0
RGSC_v3.4	13	44,773,892 - 44,774,072	UniSTS	RGSC3.4
Celera	13	43,615,827 - 43,616,007	UniSTS
RH 3.4 Map	13	111.8	UniSTS
Cytogenetic Map	13	q13	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108855	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000063882 ⟹ ENSRNOP00000060385

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	43,270,792 - 43,291,162 (+)	Ensembl
Rnor_6.0 Ensembl	13	48,607,308 - 48,627,999 (+)	Ensembl

RefSeq Acc Id:

NM_001108855 ⟹ NP_001102325

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	45,822,999 - 45,843,364 (+)	NCBI
mRatBN7.2	13	43,270,792 - 43,291,162 (+)	NCBI
Rnor_6.0	13	48,607,308 - 48,627,999 (+)	NCBI
Rnor_5.0	13	53,681,648 - 53,701,895 (+)	NCBI
RGSC_v3.4	13	44,766,706 - 44,777,526 (+)	RGD
Celera	13	43,608,641 - 43,629,021 (+)	RGD

Sequence:

show sequence

GATGGAGGGGGGTTACCACCCGCTCTGCCCCAGATCACGTTTGCCACCCACAGCCGAACACTCT
TGTCCAAGTCGGCGGGCAAGAGGCGATTGGGGACGAGCAAGCTCGACACCTCAGGCCCAGTCCG
GTCCTCACCGGCCGGAGGCGAAATACCCTGCCCCCCAGGCCACCTCCCCTCGTGGAATCGGAGC
GGCGGCCTCGCAGGAAGGCAGAAGCGAAATGTAGCGAGCCGGGTGTCGCGGTTGGACGCTCGCC
TTGGCTGGGGGTGTAGCGGGGCACTCGCGGGGGCTCGAGGAGGACGGCTGAGGGAGAGGAGTGA
TGAGAAGAGGGGGTACCCTGCATCCCCCGATTCCGCGGGCCCCTGCTACCACTCTCCAGGCGCC
CTTTCTCCCCAGCGAGGCGCAGGTGTTCCACACCAGTTCTTGTGACTTTAAGGACCAGGCAACT
GAGAAAGTACAAGATCTTCTCAAGAAGGGACGACATCTCTGGGAGAGAGGGGGAAGATAGCAGA
TACTGGGACCAGCTGAGACCAACCAAGGTGCTGTGGGAAGCTGAAGGCACCCAGCAGGAGTGGG
AAGAAGCCCCGGCCTCGGCCTCAGATCGAGGCTCCGTTCTGGACCATCTGAACTCCGTTCAGCT
TTTCACAAGAGAGGGGCTGCAGCGTCAGGCACTCCAGACTCAGGTTGAGCTCTTCCCTTCCGCA
CACTCCTGCTCTGAGGAGCTGGCCACTGAGAACCAAAGATTCCCCCTGGCACTGCGTAGAGCTG
CTGGGAGCAGGCACCCACACCCTGCTGCATCTTGTGAGGACTTTGTTTCTTTCCAGCTCCCGGG
CTGCACTGCTTGATGGGGCTGTCTTTTGGGAGAGCAGTTTTTACAGTGCCCGGTAGGAGTGGAG
AGCCGTGGGAAGAGGTCCTGCGGCACTCAAGCCTGGGTTCACCCCAAGACTAAGTTCTTTCCCA
AGTCAGAGTCGGAGAGAGAAAGAAAAATAAATAAATTCTCCCCTCCTCTCCTCCCTGCCTGTCA
TGTCCTCTAAGCCAGAGCCAAAGGACATCCACCAGCCGAACGGTACTGGCCCTACTCCCTCTCC
TTGTTCTTCGGATGGCCCTGGGCGAGAGCCCTTGGCTGGGACCTCAGAGTTCCTGGGGCCTGAT
GGGGCTGGGGTGGAAGTGGTAGTGATTGAGTCTCGAGCTAACGCCAAGGGAGTTCGGGAGGAGG
ACGCACTGCTGGAGAATGGGAGCCAGAGCAATGAGAGCGACGATGTCAGCACAGACCGGGTCCC
TGCACCACCCTCTCCGCTCAAGGAGACCTCCTTTTCCATTGGACTGCAAGTGCTGTTCCCCTTC
CTCCTGGCAGGCTTTGGGACTGTGGCAGCTGGCATGGTGCTGGACATTGTGCAGCACTGGGAGG
TCTTCCAGAAGGTGACAGAGGTCTTCATCCTGGTGCCTGCACTGCTGGGGCTCAAAGGGAACTT
GGAAATGACCCTGGCGTCGAGGCTGTCCACTGCAGCCAACATCGGACAAATGGACACACCTAAG
GAGCTCTGGCGGATGATCACGGGGAATATGGCCCTTATCCAGGTACAGGCCACAGTGGTGGGCT
TCCTGGCATCCATCGCAGCCGTCGTCTTTGGCTGGATCCCTGATGGCCACTTTAGCATCCCACA
TGCCTTCCTGCTATGTGCCAGCAGTGTGGCCACAGCCTTCATTGCCTCCTTGGTCCTGGGTATG
ATCATGATCGGAGTCATCATTGGATCGAGAAAGATTGGGATCAACCCAGACAACGTGGCCACTC
CCATCGCCGCCAGCCTGGGTGACCTCATCACCTTGGCACTCCTCTCAGGCATCAGCTGGGGACT
CTACCTGGAACTGACGCACTGGCGATACATCTACCCCCTGGTGTGTGCCTTCTTTGTGGCGTTG
CTGCCTGTCTGGGTGGTGCTGGCCCGAAGAAGCCCAGCCACAAGGGAGGTGCTGTATTCAGGCT
GGGAGCCCGTCATCATTGCCATGGCCATCAGCAGTGTGGGAGGCCTCATCTTGGACAAGACTGT
CTCGGACCCCAACTTTGCAGGAATGGCTGTCTTCACACCTGTGATTAATGGCGTCGGGGGCAAT
CTGGTGGCTGTGCAGGCCAGCCGCATCTCCACCTTCCTCCACATGAACGGCATGCCGGGGGAGA
ACTCTGAGCCAACCCCTCGCCGCTGCCCCAGTCCGTGTACCACCTTCTTCAGCCCTGACGTGAA
TTCACGCTCAGCCCGGGTCCTCTTCCTCCTTGTGGTCCCAGGACACCTGGTGTTCCTCTACACC
ATCAGCTGTATGCAGGGCGGGCACACCACCCTCACCCTCATCTTCATCATCTTCTACATGACAG
CTGCACTGCTCCAGGTGCTGATTCTCCTGTACATTGCAGACTGGATGGTGAACTGGATGTGGGG
CCGGGGCCTGGACCCCGACAACTTCTCCATCCCATACTTGACTGCTTTGGGGGACCTGCTTGGC
ACCGGGCTCCTGGCACTCAGCTTCCATGTTCTCTGGCTCATTGGGGACAGAGACACAGATGTTG
GGGACTAGCTTAGCCACTCAGCCCTTCCCCCACCCCTCTGCACTTTCTATTTGGATTTTTTTTT
TCCTTTTGTTTCCTACCCCACCCTCCCTACACTCCCACGTCTTTCTGGGATTTCACTTTGATAC
CAGATTCTCATTATTTTCAATGGGAATTTTTATACATTGAGCCAAGTTTAGATAAGAAGAATTC
GGGAAGGACAGATGGGCTGACATAAGCAGTAAAAGTAGACTTTCGAGACAATCACCAAGTGCAA
TTCCACGGTGGGTGCCTCCGGAGGAGGTAGATTGGGACCTTGGCATTCTGTCCAGCACCCGGGG
ACCTTCACATTAGCTTTAGGAACCTCGGCTCGGCCCTGATGAGAAACTCTGTCCAAGTGGGCTC
TGGGTTGTTTTGGGTTTGGTTGAACAGAGGGAGGAGGGATAATTAACACTCCTTCGCATGCACG
TGCTTTTATAGAGATGGACCAACCTCACAGCACTGGGCAGGAGAAAGTCGCTTCAGCTTCTCGT
AATCACAGCCCTGTCCCAGGCCAACCTCCCCGCAGAGTCAGGTGAACTGAGGGTTCCGTCTGCA
CACATGGGCCTTGCCCAACTGCCTGATTGCTTTCCGGTTGAATGAGTGGTGGCCTGGGCTCCTC
ACCGATCCACGTCATGCATAGGTTTCCAGAGGTCCGAGTGCCCCCTGAGTCTAGAGAACCATGT
TCAAGCCTCTCTTCATTCTCTCCACACACTCCGTCTCCGTGCAGCTTGCCAGATGGGCTTCTAG
GACTGGGGACAGGGAAGGTGGCAAACGACCTGGAGACTGACACAACCTGGGGTATCTCACTGCT
TCTCACGATGTAACTACATGGTCAGTCTTGGCCTCTGTCACTTCTGAACACACTCATTCTATCA
CACCAGGGCTCCCTCTGCCCTTTCCCTTGGCTTCTGCCCACAGACACGCATCAACCATTCACTC
ATTCAGCAAATCTCAGCCTCCCCCAGATGAGCCCTTTCCACACCACCAGCTGATCCAGCAGTCA
TTACGGGGTGCAGGGCATTGACTAGCCAGTGCTAAGGGGACCACAGCTCTACTCTCACCTCATT
CCCTAGGTTACAGAGGCCATGTGCCCCTTCAACCTGGCAGTAAACATCCCCTCTTTAGGCCCTA
ATTCTTCAGTGATTGCCAGCCCCACTGCTCAAGCAGTATCATGTCCTCAAATACCCTCCCTCAG
CTCCTCACCTCACCCCACCTCACTGCACGCTCAGGAGAAGGCTTAGAATTAGCAAGCTGGATAA
GAATTGGCTGCCTCAGCATCTGCCTTGTCTGTGATGAGAAGAAAACCAGAGCCCCTTCCCTACG
CATGCCCCAAACCACTCAACAACTGGGATGCCGGCTTTTTTTCTGGCCTGTTTGTCAGGAGCCC
ATAAATTCCTCCCCCTGTGTAGTCTAAAGGCTCAACCTCCAAGGAAAGGATTAAACAGTGTCCT
TTGTCTACCAATACTGTGCCTAGACCTAGAGACTCTTGGCCTTGTCATCACCCCACCCCCCACC
CCCAACTCCCGTCACCTGAAATCAGAACTTTAGAATTGGACAGAATCATAGAGGTTATCTAGTT
GGAGTTGTGTCAAGCAGATCAGTATGGATCTGGGCTTGTTTCTGCTCTTCCCTCTGGCCTAACT
CCACCTCAAAACTCAAGACTCGTGTAGAGGCATCATACCCTAAGACTGACCCCAGAGTCCCCAG
CCACTTGCCCTATCCTGACATCCAGAGTTGGATCAGGTTGCCTGGAGACTGAAGCATCCTTCTT
CCTTTGCCCAGAAAACAGAAAGGTAGGCGCACCCAGGCTCAGCGTGTGTTGAGTAGAGGGGCCT
GGAGTGACAGGAGAGTGACTTCAGGAGAAGATTCATTTCTTCCCGCCGGGTTGCACCTGTCGCA
TGTACTTTTGGCCTGACTGGAAGAAACAAAATTGGTTTACTTTCACATCCCTCAAAAGCTACAG
AACTGTGTCTTAAGAGAATTATTTATAGTTACTATAACTGAATTGACAAATGTCGACTTAACTG
ATAAATTATATTTGGTAAAATAAAATGGAAGTTTATTTCAAT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001102325	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM09815	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000060385.2

RefSeq Acc Id:

NP_001102325 ⟸ NM_001108855

- UniProtKB:

D3ZM22 (UniProtKB/TrEMBL), A6IC32 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSSKPEPKDIHQPNGTGPTPSPCSSDGPGREPLAGTSEFLGPDGAGVEVVVIESRANAKGVREE
DALLENGSQSNESDDVSTDRVPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWE
VFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGQMDTPKELWRMITGNMALIQVQATVVG
FLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVAT
PIAASLGDLITLALLSGISWGLYLELTHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSG
WEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGE
NSEPTPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMT
AALLQVLILLYIADWMVNWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDV
GD

hide sequence

Ensembl Acc Id:

ENSRNOP00000060385 ⟸ ENSRNOT00000063882

Protein Domains

SLC41A/MgtE integral membrane

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZM22-F1-model_v2	AlphaFold	D3ZM22	1-514	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698800

Promoter ID:

EPDNEW_R9325

Type:

initiation region

Name:

Slc41a1_1

Description:

solute carrier family 41 member 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	48,607,339 - 48,607,399	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311397	AgrOrtholog
BioCyc Gene	G2FUF-18337	BioCyc
Ensembl Genes	ENSRNOG00000042320	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000063882.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.357.20	UniProtKB/TrEMBL
InterPro	SLC41_membr_dom	UniProtKB/TrEMBL
	SLC41_membr_dom_sf	UniProtKB/TrEMBL
	SLC41A1-3	UniProtKB/TrEMBL
KEGG Report	rno:363985	UniProtKB/TrEMBL
NCBI Gene	363985	ENTREZGENE
PANTHER	PTHR16228	UniProtKB/TrEMBL
	SOLUTE CARRIER FAMILY 41 MEMBER 1	UniProtKB/TrEMBL
Pfam	MgtE	UniProtKB/TrEMBL
PhenoGen	Slc41a1	PhenoGen
RatGTEx	ENSRNOG00000042320	RatGTEx
Superfamily-SCOP	SSF161093	UniProtKB/TrEMBL
UniProt	A6IC32	ENTREZGENE, UniProtKB/TrEMBL
	D3ZM22	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-24	Slc41a1	solute carrier family 41 member 1	Slc41a1	solute carrier family 41 (magnesium transporter), member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-08-02	Slc41a1	solute carrier family 41 (magnesium transporter), member 1	Slc41a1	solute carrier family 41, member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Slc41a1	solute carrier family 41, member 1	Slc41a1_predicted	solute carrier family 41, member 1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Slc41a1_predicted	solute carrier family 41, member 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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