 Gene Ontology Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cellular Component
Molecular Function
Phenotype Annotations |
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Analyze GeneStrainQTL List |
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Cellular Component
Molecular Function
Phenotype AnnotationsGene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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Phenotype AnnotationsMammalian Phenotype
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References - curated| 1. | Bengtsson E, etal., J Biol Chem 2000 Dec 29;275(52):40695-702. |
| 2. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 3. | Hoffman MJ, etal., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1. |
| 4. | MGD data from the GO Consortium |
| 5. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 6. | RGD automated data pipeline |
| 7. | RGD automated import pipeline for gene-chemical interactions |
| 8. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
References - uncuratedGenomics
Candidate Gene StatusComparative Map Data| Prelp (Rattus norvegicus - Norway rat) |
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| PRELP (Homo sapiens - human) |
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| Prelp (Mus musculus - house mouse) |
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| Prelp (Chinchilla lanigera - long-tailed chinchilla) |
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| PRELP (Pan paniscus - bonobo/pygmy chimpanzee) |
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| PRELP (Canis lupus familiaris - dog) |
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| Prelp (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| PRELP (Sus scrofa - pig) |
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Position Markers| RH132004 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
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| High | ||||||||||||||||
| Medium | 9 | 14 | 2 | 10 | 4 | 3 | 3 | 2 | 14 | 13 | 11 | 9 | 12 | 12 | 6 | 3 |
| Low | 13 | 23 | 15 | 4 | 6 | 12 | 12 | 2 | 17 | 23 | 2 | 5 | ||||
| Below cutoff | 4 | 6 | 1 | 10 |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_053385 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_006249890 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006249891 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_008769572 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07020983 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07020984 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07020985 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075157 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075158 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075159 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF163569 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC072487 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473958 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | NM_053385 ⟹ NP_445837 | ||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
GCTAACGCAGCTTCACCAAAGGGTGGGGAGGAACAGAGGAGTGCTCCAGCGTCCAGAGGAGAGGhide sequence |
| RefSeq Acc Id: | XM_006249890 ⟹ XP_006249952 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
TTCGGAGCTGGGGACCGAGTAAGCTCTCTTAAGAAAGGCTTCTGAATGCAGAGCATGCACTGGGhide sequence |
| RefSeq Acc Id: | XM_006249891 ⟹ XP_006249953 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
AGCCAGAAGTAAGGGAGTTAAGAAAAACTTTCAGGCTGGAGACTGAGTGAAGAAGAATAAGGGAhide sequence |
| RefSeq Acc Id: | XM_008769572 ⟹ XP_008767794 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
CCTAGCCAGAAGTAAGGGAGTTAAGAAAAACTTTCAGGCTGGAGACTGAGTGAAGAAGAATAAGhide sequence |
Protein Sequences| Protein RefSeqs | NP_445837 | (Get FASTA) | NCBI Sequence Viewer |
| XP_006249952 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006249953 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_008767794 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAG23724 | (Get FASTA) | NCBI Sequence Viewer |
| AAH72487 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM09749 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM09750 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM09751 | (Get FASTA) | NCBI Sequence Viewer | |
| Q9EQP5 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_445837 ⟸ NM_053385 |
| - Peptide Label: | precursor |
| - UniProtKB: | Q9EQP5 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MRASFFWFLPLLLILASVAQGQPRPKPGIRRKPKPRPTPSFPQPHEPAEPTDLPPPLPPGPPSVhide sequence |
| RefSeq Acc Id: | XP_006249953 ⟸ XM_006249891 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | Q9EQP5 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MRASFFWFLPLLLILASVAQGQPRPKPGIRRKPKPRPTPSFPQPHEPAEPTDLPPPLPPGPPSVhide sequence |
| RefSeq Acc Id: | XP_006249952 ⟸ XM_006249890 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MPWKARAQDPGSGLCWYITWIMRASFFWFLPLLLILASVAQGQPRPKPGIRRKPKPRPTPSFPQhide sequence |
| RefSeq Acc Id: | XP_008767794 ⟸ XM_008769572 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | Q9EQP5 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MRASFFWFLPLLLILASVAQGQPRPKPGIRRKPKPRPTPSFPQPHEPAEPTDLPPPLPPGPPSVhide sequence |
TranscriptomePromoters| RGD ID: | 13698828 | |||||||||
| Promoter ID: | EPDNEW_R9349 | |||||||||
| Type: | initiation region | |||||||||
| Name: | Prelp_1 | |||||||||
| Description: | proline and arginine rich end leucine rich repeat protein | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
| Experiment Methods: | Single-end sequencing. | |||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:620226 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000003120 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000004241 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENSRNOP00000068464 | ENTREZGENE, UniProtKB/Swiss-Prot | |
| ENSRNOP00000075732 | UniProtKB/Swiss-Prot | |
| Ensembl Transcript | ENSRNOT00000004241 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENSRNOT00000076610 | ENTREZGENE, UniProtKB/Swiss-Prot | |
| ENSRNOT00000079116 | UniProtKB/Swiss-Prot | |
| Gene3D-CATH | 3.80.10.10 | UniProtKB/Swiss-Prot |
| IMAGE_CLONE | IMAGE:7104853 | IMAGE-MGC_LOAD |
| InterPro | Leu-rich_rpt | UniProtKB/Swiss-Prot |
| Leu-rich_rpt_typical-subtyp | UniProtKB/Swiss-Prot | |
| LRR_dom_sf | UniProtKB/Swiss-Prot | |
| LRRNT | UniProtKB/Swiss-Prot | |
| Prolargin | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:84400 | UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:91584 | IMAGE-MGC_LOAD |
| NCBI Gene | 84400 | ENTREZGENE |
| PANTHER | PTHR45712:SF8 | UniProtKB/Swiss-Prot |
| Pfam | LRR_1 | UniProtKB/Swiss-Prot |
| LRR_8 | UniProtKB/Swiss-Prot | |
| LRRNT | UniProtKB/Swiss-Prot | |
| PhenoGen | Prelp | PhenoGen |
| PROSITE | LRR | UniProtKB/Swiss-Prot |
| SMART | LRR_TYP | UniProtKB/Swiss-Prot |
| LRRNT | UniProtKB/Swiss-Prot | |
| UniGene | Rn.112602 | ENTREZGENE |
| UniProt | PRELP_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2016-06-15 | Prelp | proline and arginine rich end leucine rich repeat protein | Prelp | proline/arginine-rich end leucine-rich repeat protein | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2013-04-17 | Prelp | proline/arginine-rich end leucine-rich repeat protein | LOC100363743 | proline arginine-rich end leucine-rich repeat protein-like | Data Merged | 737654 | PROVISIONAL |
| 2010-05-06 | LOC100363743 | proline arginine-rich end leucine-rich repeat protein-like | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
| 2009-10-22 | Prelp | proline/arginine-rich end leucine-rich repeat protein | Prelp | proline arginine-rich end leucine-rich repeat protein | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2004-12-14 | Prelp | proline arginine-rich end leucine-rich repeat protein | Symbol and Name status set to approved | 1299863 | APPROVED | ||
| 2002-08-07 | Prelp | proline arginine-rich end leucine-rich repeat protein | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_protein | leucine-rich repeat protein, also contains a high number of proline and arginine residues | 727301 |
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| More on Prelp | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 620226 |
| Created: | 2002-08-06 |
| Species: | Rattus norvegicus |
| Last Modified: | 2019-08-20 |
| Status: | ACTIVE |
