Chit1 (chitinase 1) - Rat Genome Database

Name: Chit1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Chit1 (chitinase 1) Rattus norvegicus

Analyze

Symbol:

Chit1

Name:

chitinase 1

RGD ID:

1305646

Description:

Predicted to enable chitin binding activity and endochitinase activity. Predicted to be involved in chitin catabolic process. Predicted to be located in extracellular space. Predicted to be active in extracellular region. Orthologous to human CHIT1 (chitinase 1); PARTICIPATES IN amino sugar metabolic pathway; french type sialuria pathway; sialic acid storage disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

chitinase 1 (chitotriosidase); chitotriosidase variant 1; chitotriosidase variant 2; chitotriosidase variant 3; chitotriosidase variant 4; chitotriosidase variant 5; chitotriosidase-1; LOC289032

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CHIT1 (chitinase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Chit1 (chitinase 1 (chitotriosidase))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Chit1 (chitinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CHIT1 (chitinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Chit1 (chitinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CHIT1 (chitinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CHIT1 (chitinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Chit1 (chitinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CHI3L1 (chitinase 3 like 1)	HGNC	OrthoDB
Homo sapiens (human):	CHI3L2 (chitinase 3 like 2)	HGNC	OrthoDB
Homo sapiens (human):	CHIA (chitinase acidic)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	CHIT1 (chitinase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Chit1 (chitinase 1 (chitotriosidase))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	chia.1 (chitinase, acidic.1)	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	CTS2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	cht-1	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Cht8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder)
Drosophila melanogaster (fruit fly):	Idgf1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Idgf2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Idgf3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Idgf4	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Idgf5	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Idgf6	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)

Candidate Gene For:

Bp395

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	45,565,841 - 45,613,593 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	45,593,845 - 45,613,592 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	48,174,113 - 48,221,708 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	13	49,462,167 - 49,509,762 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	13	46,726,964 - 46,774,804 (+)	NCBI	Rnor_WKY
Rnor_6.0	13	50,947,020 - 50,994,644 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	50,974,872 - 50,994,643 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	56,000,134 - 56,046,972 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	47,095,240 - 47,109,367 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	47,059,518 - 47,123,204 (+)	NCBI
Celera	13	45,894,357 - 45,941,716 (+)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

CHITOTRIOSIDASE DEFICIENCY (ISO)

familial adult myoclonic epilepsy 5 (ISO)

gastrointestinal stromal tumor (ISO)

Gaucher's disease (ISO)

genetic disease (ISO)

Hypokalemic Periodic Paralysis, Type 1 (ISO)

parathyroid carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (ISO)

5-azacytidine (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

ALLOSAMIDIN (ISO)

arsenous acid (ISO)

atrazine (EXP,ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

chitin (ISO)

diarsenic trioxide (ISO)

dorsomorphin (ISO)

fulvestrant (ISO)

furan (EXP)

hypochlorous acid (ISO)

oxaliplatin (EXP)

paracetamol (ISO)

pioglitazone (ISO)

pirinixic acid (ISO)

propanal (ISO)

SB 431542 (ISO)

succimer (ISO)

titanium dioxide (ISO)

topotecan (EXP)

triptonide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

carbohydrate metabolic process (IEA)

chitin catabolic process (IBA,ISO)

Cellular Component

extracellular region (IBA)

extracellular space (ISO)

Molecular Function

chitin binding (IBA)

chitinase activity (IBA,ISO)

endochitinase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

amino sugar metabolic pathway (IEA,ISO)

french type sialuria pathway (ISO)

nucleotide sugar metabolic pathway (IEA)

sialic acid storage disease pathway (ISO)

Tay-Sachs disease pathway (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

albuminuria (IAGP)

salt-sensitive hypertension (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Congenic mapping and sequence analysis of the Renin locus.	Flister MJ, etal., Hypertension. 2013 Apr;61(4):850-6. doi: 10.1161/HYPERTENSIONAHA.111.01008. Epub 2013 Mar 4.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
8.	GOA pipeline	RGD automated data pipeline
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11085997	PMID:17852345	PMID:19725875	PMID:23558346	PMID:24155872	PMID:35094663

Genomics

Comparative Map Data

Chit1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	45,565,841 - 45,613,593 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	45,593,845 - 45,613,592 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	48,174,113 - 48,221,708 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	13	49,462,167 - 49,509,762 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	13	46,726,964 - 46,774,804 (+)	NCBI	Rnor_WKY
Rnor_6.0	13	50,947,020 - 50,994,644 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	50,974,872 - 50,994,643 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	56,000,134 - 56,046,972 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	47,095,240 - 47,109,367 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	47,059,518 - 47,123,204 (+)	NCBI
Celera	13	45,894,357 - 45,941,716 (+)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

CHIT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	203,216,079 - 203,230,099 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	1	203,212,827 - 203,273,641 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	203,185,207 - 203,198,801 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	201,452,418 - 201,465,399 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	199,917,451 - 199,930,433	NCBI
Celera	1	176,314,462 - 176,328,121 (-)	NCBI		Celera
Cytogenetic Map	1	q32.1	NCBI
HuRef	1	174,350,361 - 174,364,019 (-)	NCBI		HuRef
CHM1_1	1	204,607,543 - 204,621,196 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	202,478,845 - 202,492,868 (-)	NCBI		T2T-CHM13v2.0

Chit1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	134,038,980 - 134,079,279 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	134,038,980 - 134,079,278 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	134,111,242 - 134,151,541 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	134,111,242 - 134,151,540 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	136,007,819 - 136,048,013 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	135,927,653 - 135,967,847 (+)	NCBI		MGSCv36	mm8
Celera	1	136,728,484 - 136,764,033 (+)	NCBI		Celera
Cytogenetic Map	1	E4	NCBI

Chit1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	39,229,356 - 39,241,540 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	39,229,161 - 39,253,328 (-)	NCBI	ChiLan1.0	ChiLan1.0

CHIT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	1	46,115,356 - 46,134,406 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	178,816,396 - 178,875,895 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	183,112,412 - 183,126,052 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

Chit1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	72,138,798 - 72,151,126 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936567	1,376,768 - 1,385,616 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936567	1,373,727 - 1,385,694 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CHIT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	113,927,720 - 113,941,433 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	113,927,715 - 113,941,445 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	125,386,204 - 125,431,735 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CHIT1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	26,120,089 - 26,133,093 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666055	26,896,486 - 26,909,524 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Chit1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624807	7,612,293 - 7,625,535 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624807	7,612,263 - 7,625,782 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Chit1
418 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	210
Count of miRNA genes:	128
Interacting mature miRNAs:	133
Transcripts:	ENSRNOT00000035658
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	101056920	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	5994833	77046787	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	5994833	77046787	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	8897350	101631289	Rat
7411662	Foco29	Food consumption QTL 29	20.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	13	9313465	54313465	Rat
9589141	Insul28	Insulin level QTL 28	10.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	13	9313465	54313465	Rat
2317040	Aia21	Adjuvant induced arthritis QTL 21	2.75		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	9831541	54831541	Rat
2317046	Aia8	Adjuvant induced arthritis QTL 8	3.9700000286102295		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	9831541	54831541	Rat
2302275	Gluco37	Glucose level QTL 37	3.8		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	13	11929449	46193066	Rat
631645	Bp121	Blood pressure QTL 121	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	14915655	59915655	Rat
9589164	Gluco66	Glucose level QTL 66	6.67	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	15158722	60158722	Rat
1331784	Bp222	Blood pressure QTL 222	2.944		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	17694436	53050594	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	20605871	101339738	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	22301875	67301875	Rat
70170	Eae14	Experimental allergic encephalomyelitis QTL 14		0.0024	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	23203448	68203448	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	23692969	68692969	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	23692969	68692969	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	30395351	101056920	Rat
2301962	Cm72	Cardiac mass QTL 72	4.12		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	13	31241331	58363171	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	31241331	93395974	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	32284471	77284471	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	34535218	79535218	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	37262092	82262092	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	37374509	82374509	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	37374509	82374509	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	37415584	80753406	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	37415584	82415584	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	38433408	83433408	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	39754544	84754544	Rat
4145117	Mcs27	Mammary carcinoma susceptibility QTL 27		0.0001	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	13	43437904	47841255	Rat
6893344	Cm79	Cardiac mass QTL 79	1.5	0.04	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	43720770	62022792	Rat
12879436	Bp395	Blood pressure QTL 395			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	44639182	45700190	Rat
12879444	Bp397	Blood pressure QTL 397			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45049404	90049404	Rat
12879472	Bp399	Blood pressure QTL 399			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45228358	47841255	Rat
12879471	Bp398	Blood pressure QTL 398			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45514719	90514719	Rat

Markers in Region

AW531798

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	45,613,356 - 45,613,561 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	50,994,408 - 50,994,612	NCBI	Rnor6.0
Rnor_5.0	13	56,046,736 - 56,046,940	UniSTS	Rnor5.0
RGSC_v3.4	13	47,109,132 - 47,109,336	UniSTS	RGSC3.4
Celera	13	45,941,481 - 45,941,685	UniSTS
RH 3.4 Map	13	183.9	UniSTS
Cytogenetic Map	13	q13	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium					5						6	11
Low	3	35	45	29	14	29	8	11	59	35	35		8
Below cutoff		8	8	8		8			15

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001079689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001270846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001270847	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001270848	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598698	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090435	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090436	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090437	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC117152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ286232	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ923316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ923317	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ923318	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ923319	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ923320	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000242	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000035658 ⟹ ENSRNOP00000036477

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	45,604,183 - 45,613,592 (+)	Ensembl
Rnor_6.0 Ensembl	13	50,977,431 - 50,994,643 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000080768 ⟹ ENSRNOP00000070204

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	45,593,845 - 45,613,592 (+)	Ensembl
Rnor_6.0 Ensembl	13	50,974,872 - 50,994,643 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099352 ⟹ ENSRNOP00000096437

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	45,593,845 - 45,613,415 (+)	Ensembl

RefSeq Acc Id:

NM_001079689 ⟹ NP_001073157

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	45,593,845 - 45,613,592 (+)	NCBI
Rnor_6.0	13	50,974,872 - 50,994,643 (+)	NCBI
Rnor_5.0	13	56,000,134 - 56,046,972 (+)	NCBI
RGSC_v3.4	13	47,095,240 - 47,109,367 (+)	RGD
Celera	13	45,922,360 - 45,941,716 (+)	NCBI

Sequence:

show sequence

GGACACCACTGAGGTGGCCATGGTAAGAAGCTGTATCAGGCAGGGTCTGATTAAAGTGTCTCAA
AGGACACCCTGGCTGCTCCGGAAGTGCCAGCAGAGGGCAGAGAGGAAGGAGGGAACTCAGAGAA
GAGGCTCTGTTGGTGTGCAGGGTACCAGCTGACACCATCGTGGAGGTGGAGGAGATAGGCCAGC
TAGTAACACCTGGCCATTGAGGGTGGAGAAAAGAGGGAGTTTCTATGTGTGATAGTTGGCATAT
AGTTGGCCCAGGGAGTGGCACTATTAAAAGATGTGACTCTGTTGGAGTGGGTGTGTCACTGTGC
ATGTGGGTTTTAAGACCCTCATCTTGGCTGCCTGGGAGTATTCTGTTAGTAGCCTTCAGATGAA
GATGTAGAACTCTCAGCTCCTCCTGCACCATGCCTGCCTGGATGCTGCCATGTTCCCACCCTGT
TGATAATGGACTGAACCTCTGAACCTGTATCCATTTCAACATTTCTGGCTGTGTGGCAGCAGGC
CAGCCTGAGGAGAGCAGAGCAGGACCTGTGGAGCCGCTCCTCACAGAGCTCTATCTGCTGGAGG
CAGGGTCATGGTGCAGTCCCTGGCCTTGGCAGGTGTGACGACTCTGCTGATGATCCAGTGGGGC
TCTGCTGCAAAACTGTTCTGCTACTTCACCAACTGGGCCCAGTACCGGTCCGGGGCAGCTCGAT
TCCTACCTAGGGATGTGGATCCCAACCTGTGTACCCATGTCATCTATGCCTTTGCTGGACTGAA
CAACCACCAGGTCAGCACTGTAGAGCCCAATGACGAGCTTTTCTACCAAGAGCTGAACAGCCTA
AAGAAGAGGAACCCCAAGCTCAAGACCCTGTTAGCCGTCGGGGGCTGGAGCTTTGGTACCCAGA
AGTTCACAGACATGGTGGCCACAGCCAGCACCCGGCAGACCTTTGTCAACTCAGCTCTCTCGTT
CCTGCGCACTCATGGTTTTGACGGCCTTGACCTTGACTGGGAATACCCAGGAAGCCGAGGGAGC
CCAGCAGTAGACAAAGAGAGATTCACAGCGCTGATACAGGATTTGGCCAAAGCCTTCCAGGAGG
AAGCCCGGGCCTCAGGGAAAAGTCGCCTCCTTCTGACTGCAGCTGTACCAACTGGTCGAGGCCA
TGTGGATGCTGGTTATGAGGTGGACAAGATTGTTCAGAGTTTGGATTTCATCAACCTTATGGCC
TACGACTTCCACAGCTCCTGGGACAAGACCACAGGGCACAACAGCCCCCTCTACAAAAGGCAAG
GAGAGACTGGGAAAGATGCTGAAAAAAATGTGGATGCTGCTGTGACGCTCTGGCTGCAGAAGGG
GACCCCTGCCAGCAAACTGATGCTTGGCATGCCCGCCTACGGACGCTCCTTCACCTTGGCCTCC
TCATCAGACAGTGGAGTTGGGGCTCCAGCCACAGGACCTGGGGCCCCAGGCCCCTATACTAAGG
AAAAGGGGATACTGGTTTACTTTGAGGTCTGCTCCTGGAAGGGAAAACAGAGAATCGAGGACCA
GAAGGTGCCCTATGTCTCCCAGGGCAACCAATGGGTGGGATTTGATGACAGGGAAAGCTTCAGA
GCCAAGGCTGCCTATGTGAAACAGAAGGGACTGGGAGGGGCCATGGTCTGGATTCTGGATGGGG
ATGACTTCAAAGGTTCCTTCTGCAACGAGGGCCAGTACCCTCTCATCCGGACACTACACCAGGA
GCTGAGCCTTTCATCCGGGCCTCCAAGAAGCCCAGAACAGGAAGTACCTGGGCCACACCAGCCT
TCTGAGCCCGAGCAGGGCCCCAGCCCAGGGCTAGATGACTTCTGCCAAGGCAAAGCTGATGGGC
TCTACCCCAACCCTACAGAAAAGTCCAGTTTCTACAGCTGTGGAGGGGGGCGACTGTTCCAGCA
CAGCTGCCCCCCAGGCCTGGTGTTTATCGACTCTTGCAAATGCTGTACCTGGGGTTGAGTCCCT
GGAGTCCCATCAGACTCCAGTCTGAGGCCAGGCTTGGGACGCCCCGCCCCCTGCCAGTAGCTTG
CTTCTGCTTTCCCTGGGGGGCTGCAGGAGGCCTCTCTGTTCTTTCCCTGACTCGGCCTCTGCTC
AGCTTTTTGGCTTCCTTTTTGTCTCTTCTAGGCTCCCGCTTTACCTGAAAAAATAAACTTATTT
TTCACCCCCG

hide sequence

RefSeq Acc Id:

NM_001270846 ⟹ NP_001257775

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	45,593,845 - 45,613,592 (+)	NCBI
Rnor_6.0	13	50,974,872 - 50,994,643 (+)	NCBI
Rnor_5.0	13	56,000,134 - 56,046,972 (+)	NCBI
Celera	13	45,922,360 - 45,941,716 (+)	NCBI

Sequence:

show sequence

GGACACCACTGAGGTGGCCATGGAAAGCAGAGTCACAGGGCACCATGCGCTCCTCAACCAACTT
CTGAAGGACCTTCAAGGGAGCTTATCTCAGAGGTGACAGATCCCTGATGACCTCAGAGGGTATC
CATTTCAACATTTCTGGCTGTGTGGCAGCAGGCCAGCCTGAGGAGAGCAGAGCAGGACCTGTGG
AGCCGCTCCTCACAGAGCTCTATCTGCTGGAGGCAGGGTCATGGTGCAGTCCCTGGCCTTGGCA
GGTGTGACGACTCTGCTGATGATCCAGTGGGGCTCTGCTGCAAAACTGTTCTGCTACTTCACCA
ACTGGGCCCAGTACCGGTCCGGGGCAGCTCGATTCCTACCTAGGGATGTGGATCCCAACCTGTG
TACCCATGTCATCTATGCCTTTGCTGGACTGAACAACCACCAGGTCAGCACTGTAGAGCCCAAT
GACGAGCTTTTCTACCAAGAGCTGAACAGCCTAAAGAAGAGGAACCCCAAGCTCAAGACCCTGT
TAGCCGTCGGGGGCTGGAGCTTTGGTACCCAGAAGTTCACAGACATGGTGGCCACAGCCAGCAC
CCGGCAGACCTTTGTCAACTCAGCTCTCTCGTTCCTGCGCACTCATGGTTTTGACGGCCTTGAC
CTTGACTGGGAATACCCAGGAAGCCGAGGGAGCCCAGCAGTAGACAAAGAGAGATTCACAGCGC
TGATACAGGATTTGGCCAAAGCCTTCCAGGAGGAAGCCCGGGCCTCAGGGAAAAGTCGCCTCCT
TCTGACTGCAGCTGTACCAACTGGTCGAGGCCATGTGGATGCTGGTTATGAGGTGGACAAGATT
GTTCAGAGTTTGGATTTCATCAACCTTATGGCCTACGACTTCCACAGCTCCTGGGACAAGACCA
CAGGGCACAACAGCCCCCTCTACAAAAGGCAAGGAGAGACTGGGAAAGATGCTGAAAAAAATGT
GGATGCTGCTGTGACGCTCTGGCTGCAGAAGGGGACCCCTGCCAGCAAACTGATGCTTGGCATG
CCCGCCTACGGACGCTCCTTCACCTTGGCCTCCTCATCAGACAGTGGAGTTGGGGCTCCAGCCA
CAGGACCTGGGGCCCCAGGCCCCTATACTAAGGAAAAGGGGATACTGGTTTACTTTGAGGTCTG
CTCCTGGAAGGGAAAACAGAGAATCGAGGACCAGAAGGTGCCCTATGTCTCCCAGGGCAACCAA
TGGGTGGGATTTGATGACAGGGAAAGCTTCAGAGCCAAGGCTGCCTATGTGAAACAGAAGGGAC
TGGGAGGGGCCATGGTCTGGATTCTGGATGGGGATGACTTCAAAGGTTCCTTCTGCAACGAGGG
CCAGTACCCTCTCATCCGGACACTACACCAGGAGCTGAGCCTTTCATCCGGGCCTCCAAGAAGC
CCAGAACAGGAAGTACCTGGGCCACACCAGCCTTCTGAGCCCGAGCAGGGCCCCAGCCCAGGGC
TAGATGACTTCTGCCAAGGCAAAGCTGATGGGCTCTACCCCAACCCTACAGAAAAGTCCAGTTT
CTACAGCTGTGGAGGGGGGCGACTGTTCCAGCACAGCTGCCCCCCAGGCCTGGTGTTTATCGAC
TCTTGCAAATGCTGTACCTGGGGTTGAGTCCCTGGAGTCCCATCAGACTCCAGTCTGAGGCCAG
GCTTGGGACGCCCCGCCCCCTGCCAGTAGCTTGCTTCTGCTTTCCCTGGGGGGCTGCAGGAGGC
CTCTCTGTTCTTTCCCTGACTCGGCCTCTGCTCAGCTTTTTGGCTTCCTTTTTGTCTCTTCTAG
GCTCCCGCTTTACCTGAAAAAATAAACTTATTTTTCACCCCCG

hide sequence

RefSeq Acc Id:

NM_001270847 ⟹ NP_001257776

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	45,593,845 - 45,613,592 (+)	NCBI
Rnor_6.0	13	50,974,872 - 50,994,643 (+)	NCBI
Rnor_5.0	13	56,000,134 - 56,046,972 (+)	NCBI
Celera	13	45,922,360 - 45,941,716 (+)	NCBI

Sequence:

show sequence

GGACACCACTGAGGTGGCCATGGTATCCATTTCAACATTTCTGGCTGTGTGGCAGCAGGCCAGC
CTGAGGAGAGCAGAGCAGGACCTGTGGAGCCGCTCCTCACAGAGCTCTATCTGCTGGAGGCAGG
GTCATGGTGCAGTCCCTGGCCTTGGCAGGTGTGACGACTCTGCTGATGATCCAGTGGGGCTCTG
CTGCAAAACTGTTCTGCTACTTCACCAACTGGGCCCAGTACCGGTCCGGGGCAGCTCGATTCCT
ACCTAGGGATGTGGATCCCAACCTGTGTACCCATGTCATCTATGCCTTTGCTGGACTGAACAAC
CACCAGGTCAGCACTGTAGAGCCCAATGACGAGCTTTTCTACCAAGAGCTGAACAGCCTAAAGA
AGAGGAACCCCAAGCTCAAGACCCTGTTAGCCGTCGGGGGCTGGAGCTTTGGTACCCAGAAGTT
CACAGACATGGTGGCCACAGCCAGCACCCGGCAGACCTTTGTCAACTCAGCTCTCTCGTTCCTG
CGCACTCATGGTTTTGACGGCCTTGACCTTGACTGGGAATACCCAGGAAGCCGAGGGAGCCCAG
CAGTAGACAAAGAGAGATTCACAGCGCTGATACAGGATTTGGCCAAAGCCTTCCAGGAGGAAGC
CCGGGCCTCAGGGAAAAGTCGCCTCCTTCTGACTGCAGCTGTACCAACTGGTCGAGGCCATGTG
GATGCTGGTTATGAGGTGGACAAGATTGTTCAGAGTTTGGATTTCATCAACCTTATGGCCTACG
ACTTCCACAGCTCCTGGGACAAGACCACAGGGCACAACAGCCCCCTCTACAAAAGGCAAGGAGA
GACTGGGAAAGATGCTGAAAAAAATGTGGATGCTGCTGTGACGCTCTGGCTGCAGAAGGGGACC
CCTGCCAGCAAACTGATGCTTGGCATGCCCGCCTACGGACGCTCCTTCACCTTGGCCTCCTCAT
CAGACAGTGGAGTTGGGGCTCCAGCCACAGGACCTGGGGCCCCAGGCCCCTATACTAAGGAAAA
GGGGATACTGGTTTACTTTGAGGTCTGCTCCTGGAAGGGAAAACAGAGAATCGAGGACCAGAAG
GTGCCCTATGTCTCCCAGGGCAACCAATGGGTGGGATTTGATGACAGGGAAAGCTTCAGAGCCA
AGGCTGCCTATGTGAAACAGAAGGGACTGGGAGGGGCCATGGTCTGGATTCTGGATGGGGATGA
CTTCAAAGGTTCCTTCTGCAACGAGGGCCAGTACCCTCTCATCCGGACACTACACCAGGAGCTG
AGCCTTTCATCCGGGCCTCCAAGAAGCCCAGAACAGGAAGTACCTGGGCCACACCAGCCTTCTG
AGCCCGAGCAGGGCCCCAGCCCAGGGCTAGATGACTTCTGCCAAGGCAAAGCTGATGGGCTCTA
CCCCAACCCTACAGAAAAGTCCAGTTTCTACAGCTGTGGAGGGGGGCGACTGTTCCAGCACAGC
TGCCCCCCAGGCCTGGTGTTTATCGACTCTTGCAAATGCTGTACCTGGGGTTGAGTCCCTGGAG
TCCCATCAGACTCCAGTCTGAGGCCAGGCTTGGGACGCCCCGCCCCCTGCCAGTAGCTTGCTTC
TGCTTTCCCTGGGGGGCTGCAGGAGGCCTCTCTGTTCTTTCCCTGACTCGGCCTCTGCTCAGCT
TTTTGGCTTCCTTTTTGTCTCTTCTAGGCTCCCGCTTTACCTGAAAAAATAAACTTATTTTTCA
CCCCCG

hide sequence

RefSeq Acc Id:

NM_001270848 ⟹ NP_001257777

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	45,565,841 - 45,613,592 (+)	NCBI
Rnor_6.0	13	50,947,020 - 50,994,643 (+)	NCBI
Rnor_5.0	13	56,000,134 - 56,046,972 (+)	NCBI
Celera	13	45,894,357 - 45,941,716 (+)	NCBI

Sequence:

show sequence

GCAGTTGGAACAACTTGTAGAGCTCTCAGCAACTTCTCCAACACCAAGTCGGCCTGGATGCTGC
CATGCTCCCCACCATGATGATAATGGACTGAGCCTCTGAAACAGTATCCATTTCAACATTTCTG
GCTGTGTGGCAGCAGGCCAGCCTGAGGAGAGCAGAGCAGGACCTGTGGAGCCGCTCCTCACAGA
GCTCTATCTGCTGGAGGCAGGGTCATGGTGCAGTCCCTGGCCTTGGCAGGTGTGACGACTCTGC
TGATGATCCAGTGGGGCTCTGCTGCAAAACTGTTCTGCTACTTCACCAACTGGGCCCAGTACCG
GTCCGGGGCAGCTCGATTCCTACCTAGGGATGTGGATCCCAACCTGTGTACCCATGTCATCTAT
GCCTTTGCTGGACTGAACAACCACCAGGTCAGCACTGTAGAGCCCAATGACGAGCTTTTCTACC
AAGAGCTGAACAGCCTAAAGAAGAGGAACCCCAAGCTCAAGACCCTGTTAGCCGTCGGGGGCTG
GAGCTTTGGTACCCAGAAGTTCACAGACATGGTGGCCACAGCCAGCACCCGGCAGACCTTTGTC
AACTCAGCTCTCTCGTTCCTGCGCACTCATGGTTTTGACGGCCTTGACCTTGACTGGGAATACC
CAGGAAGCCGAGGGAGCCCAGCAGTAGACAAAGAGAGATTCACAGCGCTGATACAGGATTTGGC
CAAAGCCTTCCAGGAGGAAGCCCGGGCCTCAGGGAAAAGTCGCCTCCTTCTGACTGCAGCTGTA
CCAACTGGTCGAGGCCATGTGGATGCTGGTTATGAGGTGGACAAGATTGTTCAGAGTTTGGATT
TCATCAACCTTATGGCCTACGACTTCCACAGCTCCTGGGACAAGACCACAGGGCACAACAGCCC
CCTCTACAAAAGGCAAGGAGAGACTGGGAAAGATGCTGAAAAAAATGTGGATGCTGCTGTGACG
CTCTGGCTGCAGAAGGGGACCCCTGCCAGCAAACTGATGCTTGGCATGCCCGCCTACGGACGCT
CCTTCACCTTGGCCTCCTCATCAGACAGTGGAGTTGGGGCTCCAGCCACAGGACCTGGGGCCCC
AGGCCCCTATACTAAGGAAAAGGGGATACTGGTTTACTTTGAGGTCTGCTCCTGGAAGGGAAAA
CAGAGAATCGAGGACCAGAAGGTGCCCTATGTCTCCCAGGGCAACCAATGGGTGGGATTTGATG
ACAGGGAAAGCTTCAGAGCCAAGGCTGCCTATGTGAAACAGAAGGGACTGGGAGGGGCCATGGT
CTGGATTCTGGATGGGGATGACTTCAAAGGTTCCTTCTGCAACGAGGGCCAGTACCCTCTCATC
CGGACACTACACCAGGAGCTGAGCCTTTCATCCGGGCCTCCAAGAAGCCCAGAACAGGAAGTAC
CTGGGCCACACCAGCCTTCTGAGCCCGAGCAGGGCCCCAGCCCAGGGCTAGATGACTTCTGCCA
AGGCAAAGCTGATGGGCTCTACCCCAACCCTACAGAAAAGTCCAGTTTCTACAGCTGTGGAGGG
GGGCGACTGTTCCAGCACAGCTGCCCCCCAGGCCTGGTGTTTATCGACTCTTGCAAATGCTGTA
CCTGGGGTTGAGTCCCTGGAGTCCCATCAGACTCCAGTCTGAGGCCAGGCTTGGGACGCCCCGC
CCCCTGCCAGTAGCTTGCTTCTGCTTTCCCTGGGGGGCTGCAGGAGGCCTCTCTGTTCTTTCCC
TGACTCGGCCTCTGCTCAGCTTTTTGGCTTCCTTTTTGTCTCTTCTAGGCTCCCGCTTTACCTG
AAAAAATAAACTTATTTTTCACCCCCG

hide sequence

RefSeq Acc Id:

XM_039090435 ⟹ XP_038946363

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	45,600,098 - 45,613,593 (+)	NCBI

RefSeq Acc Id:

XM_039090436 ⟹ XP_038946364

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	45,600,095 - 45,613,593 (+)	NCBI

RefSeq Acc Id:

XM_039090437 ⟹ XP_038946365

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	45,600,086 - 45,613,415 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001073157	(Get FASTA)	NCBI Sequence Viewer
	NP_001257775	(Get FASTA)	NCBI Sequence Viewer
	NP_001257776	(Get FASTA)	NCBI Sequence Viewer
	NP_001257777	(Get FASTA)	NCBI Sequence Viewer
	XP_038946363	(Get FASTA)	NCBI Sequence Viewer
	XP_038946364	(Get FASTA)	NCBI Sequence Viewer
	XP_038946365	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ABB89471	(Get FASTA)	NCBI Sequence Viewer
	ABL06995	(Get FASTA)	NCBI Sequence Viewer
	ABL06996	(Get FASTA)	NCBI Sequence Viewer
	ABL06997	(Get FASTA)	NCBI Sequence Viewer
	ABL06998	(Get FASTA)	NCBI Sequence Viewer
	ABL06999	(Get FASTA)	NCBI Sequence Viewer
	EDM09742	(Get FASTA)	NCBI Sequence Viewer
	EDM09743	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001073157 ⟸ NM_001079689
- Peptide Label:	precursor
- UniProtKB:	A0S5V8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVQSLALAGVTTLLMIQWGSAAKLFCYFTNWAQYRSGAARFLPRDVDPNLCTHVIYAFAGLNNH QVSTVEPNDELFYQELNSLKKRNPKLKTLLAVGGWSFGTQKFTDMVATASTRQTFVNSALSFLR THGFDGLDLDWEYPGSRGSPAVDKERFTALIQDLAKAFQEEARASGKSRLLLTAAVPTGRGHVD AGYEVDKIVQSLDFINLMAYDFHSSWDKTTGHNSPLYKRQGETGKDAEKNVDAAVTLWLQKGTP ASKLMLGMPAYGRSFTLASSSDSGVGAPATGPGAPGPYTKEKGILVYFEVCSWKGKQRIEDQKV PYVSQGNQWVGFDDRESFRAKAAYVKQKGLGGAMVWILDGDDFKGSFCNEGQYPLIRTLHQELS LSSGPPRSPEQEVPGPHQPSEPEQGPSPGLDDFCQGKADGLYPNPTEKSSFYSCGGGRLFQHSC PPGLVFIDSCKCCTWG hide sequence

RefSeq Acc Id:	NP_001257777 ⟸ NM_001270848
- Peptide Label:	precursor
- UniProtKB:	A0S5V8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVQSLALAGVTTLLMIQWGSAAKLFCYFTNWAQYRSGAARFLPRDVDPNLCTHVIYAFAGLNNH QVSTVEPNDELFYQELNSLKKRNPKLKTLLAVGGWSFGTQKFTDMVATASTRQTFVNSALSFLR THGFDGLDLDWEYPGSRGSPAVDKERFTALIQDLAKAFQEEARASGKSRLLLTAAVPTGRGHVD AGYEVDKIVQSLDFINLMAYDFHSSWDKTTGHNSPLYKRQGETGKDAEKNVDAAVTLWLQKGTP ASKLMLGMPAYGRSFTLASSSDSGVGAPATGPGAPGPYTKEKGILVYFEVCSWKGKQRIEDQKV PYVSQGNQWVGFDDRESFRAKAAYVKQKGLGGAMVWILDGDDFKGSFCNEGQYPLIRTLHQELS LSSGPPRSPEQEVPGPHQPSEPEQGPSPGLDDFCQGKADGLYPNPTEKSSFYSCGGGRLFQHSC PPGLVFIDSCKCCTWG hide sequence

RefSeq Acc Id:	NP_001257775 ⟸ NM_001270846
- Peptide Label:	precursor
- UniProtKB:	A0S5V8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVQSLALAGVTTLLMIQWGSAAKLFCYFTNWAQYRSGAARFLPRDVDPNLCTHVIYAFAGLNNH QVSTVEPNDELFYQELNSLKKRNPKLKTLLAVGGWSFGTQKFTDMVATASTRQTFVNSALSFLR THGFDGLDLDWEYPGSRGSPAVDKERFTALIQDLAKAFQEEARASGKSRLLLTAAVPTGRGHVD AGYEVDKIVQSLDFINLMAYDFHSSWDKTTGHNSPLYKRQGETGKDAEKNVDAAVTLWLQKGTP ASKLMLGMPAYGRSFTLASSSDSGVGAPATGPGAPGPYTKEKGILVYFEVCSWKGKQRIEDQKV PYVSQGNQWVGFDDRESFRAKAAYVKQKGLGGAMVWILDGDDFKGSFCNEGQYPLIRTLHQELS LSSGPPRSPEQEVPGPHQPSEPEQGPSPGLDDFCQGKADGLYPNPTEKSSFYSCGGGRLFQHSC PPGLVFIDSCKCCTWG hide sequence

RefSeq Acc Id:	NP_001257776 ⟸ NM_001270847
- Peptide Label:	precursor
- UniProtKB:	A0S5V8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVQSLALAGVTTLLMIQWGSAAKLFCYFTNWAQYRSGAARFLPRDVDPNLCTHVIYAFAGLNNH QVSTVEPNDELFYQELNSLKKRNPKLKTLLAVGGWSFGTQKFTDMVATASTRQTFVNSALSFLR THGFDGLDLDWEYPGSRGSPAVDKERFTALIQDLAKAFQEEARASGKSRLLLTAAVPTGRGHVD AGYEVDKIVQSLDFINLMAYDFHSSWDKTTGHNSPLYKRQGETGKDAEKNVDAAVTLWLQKGTP ASKLMLGMPAYGRSFTLASSSDSGVGAPATGPGAPGPYTKEKGILVYFEVCSWKGKQRIEDQKV PYVSQGNQWVGFDDRESFRAKAAYVKQKGLGGAMVWILDGDDFKGSFCNEGQYPLIRTLHQELS LSSGPPRSPEQEVPGPHQPSEPEQGPSPGLDDFCQGKADGLYPNPTEKSSFYSCGGGRLFQHSC PPGLVFIDSCKCCTWG hide sequence

RefSeq Acc Id:

ENSRNOP00000070204 ⟸ ENSRNOT00000080768

RefSeq Acc Id:

ENSRNOP00000036477 ⟸ ENSRNOT00000035658

RefSeq Acc Id:	XP_038946365 ⟸ XM_039090437
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6AV32 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038946364 ⟸ XM_039090436
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038946363 ⟸ XM_039090435
- Peptide Label:	isoform X1
- UniProtKB:	A0S5V8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000096437 ⟸ ENSRNOT00000099352

Protein Domains

Chitin-binding type-2 GH18

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0S5V8-F1-model_v2	AlphaFold	A0S5V8	1-464	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305646	AgrOrtholog
BioCyc Gene	G2FUF-18253	BioCyc
Ensembl Genes	ENSRNOG00000028072	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000036477	ENTREZGENE
	ENSRNOP00000036477.5	UniProtKB/TrEMBL
	ENSRNOP00000070204	ENTREZGENE
	ENSRNOP00000070204.1	UniProtKB/TrEMBL
	ENSRNOP00000096437	ENTREZGENE
	ENSRNOP00000096437.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000035658	ENTREZGENE
	ENSRNOT00000035658.6	UniProtKB/TrEMBL
	ENSRNOT00000080768	ENTREZGENE
	ENSRNOT00000080768.2	UniProtKB/TrEMBL
	ENSRNOT00000099352	ENTREZGENE
	ENSRNOT00000099352.1	UniProtKB/TrEMBL
Gene3D-CATH	3.10.50.10	UniProtKB/TrEMBL
	Glycosidases	UniProtKB/TrEMBL
InterPro	Chitin-bd_dom_sf	UniProtKB/TrEMBL
	Chitin-bd_peritrophin-A	UniProtKB/TrEMBL
	Chitinase_II	UniProtKB/TrEMBL
	Chitinase_insertion	UniProtKB/TrEMBL
	Glyco_hydro18cat	UniProtKB/TrEMBL
	Glyco_hydro_18_chit_AS	UniProtKB/TrEMBL
	Glyco_hydro_catalytic_core	UniProtKB/TrEMBL
KEGG Report	rno:289032	UniProtKB/TrEMBL
NCBI Gene	289032	ENTREZGENE
PANTHER	CHITINASE	UniProtKB/TrEMBL
	CHITOTRIOSIDASE-1	UniProtKB/TrEMBL
Pfam	CBM_14	UniProtKB/TrEMBL
	Glyco_hydro_18	UniProtKB/TrEMBL
PhenoGen	Chit1	PhenoGen
PROSITE	CHIT_BIND_II	UniProtKB/TrEMBL
	CHITINASE_18	UniProtKB/TrEMBL
	GH18_2	UniProtKB/TrEMBL
SMART	Glyco_18	UniProtKB/TrEMBL
Superfamily-SCOP	Chitin_bind_PerA	UniProtKB/TrEMBL
	Glyco_hydro_cat	UniProtKB/TrEMBL
	SSF54556	UniProtKB/TrEMBL
UniProt	A0A8I6AV32	ENTREZGENE, UniProtKB/TrEMBL
	A0S5V8	ENTREZGENE, UniProtKB/TrEMBL
	F7ER89_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-09	Chit1	chitinase 1	Chit1	chitinase 1 (chitotriosidase)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Chit1	chitinase 1 (chitotriosidase)	Chit1_predicted	chitinase 1 (chitotriosidase) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Chit1_predicted	chitinase 1 (chitotriosidase) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Mammalian Phenotype