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Gene: Lct (lactase) Rattus norvegicus
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Symbol: Lct
Name: lactase
Description: Exhibits lactase activity and transferase activity. Involved in several processes, including response to iron(II) ion; response to lead ion; and response to nickel cation. Localizes to the brush border. Used to study diarrhea. Biomarker of colitis. Orthologous to human LCT (lactase); PARTICIPATES IN galactose metabolic pathway; galactosemia pathway; lactose degradation pathway; INTERACTS WITH acetylsalicylic acid; aldehydo-D-glucose; alpha-D-galactose.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: lactase-glycosylceramidase; lactase-phlorizin hydrolase; Lph
Orthologs:
Homo sapiens (human) : LCT (lactase)  HGNC  Alliance
Mus musculus (house mouse) : Lct (lactase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lct (lactase)
Pan paniscus (bonobo/pygmy chimpanzee) : LCT (lactase)
Canis lupus familiaris (dog) : LCT (lactase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lct (lactase)
Sus scrofa (pig) : LOC100625897 (lactase-phlorizin hydrolase)
Chlorocebus sabaeus (green monkey) : LCT (lactase)
Heterocephalus glaber (naked mole-rat) : Lct (lactase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01344,998,414 - 45,040,593 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1344,998,414 - 45,040,593 (-)Ensembl
Rnor_5.01350,083,769 - 50,125,203 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41340,990,315 - 41,043,388 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11341,017,068 - 41,018,494 (-)NCBI
Celera1340,155,673 - 40,198,507 (-)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lct
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620823
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.