Nckap5 (NCK-associated protein 5) - Rat Genome Database

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Gene: Nckap5 (NCK-associated protein 5) Rattus norvegicus
Analyze
Symbol: Nckap5
Name: NCK-associated protein 5
RGD ID: 1564507
Description: Predicted to be involved in microtubule bundle formation and microtubule depolymerization. Predicted to be active in microtubule plus-end. Used to study proteinuria. Orthologous to human NCKAP5 (NCK associated protein 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; atrazine.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC363974; Nap5; RGD1564507; similar to Nck-associated protein 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Nckap5em1Mcwi   Nckap5em3Mcwi   Nckap5em2Mcwi   Nckap5em4Mcwi  
Genetic Models: SS-Nckap5em2Mcwi SS-Nckap5em1Mcwi SS-Nckap5em3Mcwi SS-Nckap5em3Mcwi-/- SS-Nckap5em1Mcwi-/- SS-Nckap5em2Mcwi-/- SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi
Candidate Gene For: Bp401
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81339,922,576 - 40,835,849 (-)NCBIGRCr8
mRatBN7.21337,369,948 - 38,283,257 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1337,370,792 - 38,283,268 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01342,265,875 - 43,049,232 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1342,265,806 - 42,885,440 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01347,369,687 - 48,273,649 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41338,444,115 - 39,275,959 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1337,164,941 - 37,726,609 (-)NCBICelera
Cytogenetic Map13q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
amenorrhea  (ISO)
proteinuria  (IAGP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Narrowing a region on rat chromosome 13 that protects against hypertension in Dahl SS-13BN congenic strains. Moreno C, etal., Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1530-5. doi: 10.1152/ajpheart.01026.2010. Epub 2011 Jan 21.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation

Genomics

Comparative Map Data
Nckap5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81339,922,576 - 40,835,849 (-)NCBIGRCr8
mRatBN7.21337,369,948 - 38,283,257 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1337,370,792 - 38,283,268 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01342,265,875 - 43,049,232 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1342,265,806 - 42,885,440 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01347,369,687 - 48,273,649 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41338,444,115 - 39,275,959 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1337,164,941 - 37,726,609 (-)NCBICelera
Cytogenetic Map13q12NCBI
NCKAP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382132,671,788 - 133,674,836 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2132,671,788 - 133,568,463 (-)EnsemblGRCh38hg38GRCh38
GRCh372133,429,361 - 134,326,034 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362133,145,842 - 134,042,501 (-)NCBINCBI36Build 36hg18NCBI36
Celera2127,144,620 - 128,041,268 (-)NCBICelera
Cytogenetic Map2q21.2NCBI
HuRef2125,422,804 - 126,319,705 (-)NCBIHuRef
CHM1_12133,434,613 - 134,331,480 (-)NCBICHM1_1
T2T-CHM13v2.02133,110,139 - 134,114,523 (-)NCBIT2T-CHM13v2.0
Nckap5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391125,841,373 - 126,758,529 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1125,841,357 - 126,758,536 (-)EnsemblGRCm39 Ensembl
GRCm381125,913,636 - 126,830,796 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1125,913,620 - 126,830,799 (-)EnsemblGRCm38mm10GRCm38
MGSCv371127,810,213 - 128,727,209 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361127,741,182 - 128,320,473 (-)NCBIMGSCv36mm8
Celera1128,572,707 - 129,481,953 (-)NCBICelera
Cytogenetic Map1E3NCBI
cM Map154.7NCBI
Nckap5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955440267,717 - 1,023,489 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955440266,389 - 1,159,224 (-)NCBIChiLan1.0ChiLan1.0
NCKAP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21341,238,079 - 42,239,451 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B41,253,057 - 42,254,421 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B26,201,986 - 27,200,699 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B136,770,382 - 137,622,004 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B136,771,529 - 137,621,963 (-)Ensemblpanpan1.1panPan2
NCKAP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11935,631,900 - 36,588,124 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1935,632,939 - 36,449,082 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1935,861,560 - 36,822,017 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01937,066,848 - 38,035,511 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1937,066,864 - 37,944,664 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11935,715,146 - 36,677,068 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01935,875,120 - 36,840,359 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01937,094,072 - 38,067,908 (-)NCBIUU_Cfam_GSD_1.0
Nckap5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530384,498,611 - 85,418,181 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646956,199,522 - 57,025,906 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646956,199,988 - 56,762,974 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NCKAP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1518,801,095 - 19,521,418 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11518,411,093 - 19,462,362 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21521,366,174 - 21,626,286 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NCKAP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11016,942,009 - 18,232,033 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1016,942,071 - 17,684,017 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660614,586,378 - 5,609,346 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nckap5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473232,072,125 - 32,730,105 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473232,075,335 - 32,992,428 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nckap5
6189 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:204
Count of miRNA genes:91
Interacting mature miRNAs:99
Transcripts:ENSRNOT00000038020, ENSRNOT00000071910, ENSRNOT00000075690
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
61453Pur1Proteinuria QTL 118.06urine total protein amount (VT:0000032)urine protein level (CMO:0000591)133453521837415726Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131192944945417941Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2303030Bp327Blood pressure QTL 327arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133039535141184251Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13599466844807491Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131192944946193066Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133124133158363171Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
2292232Pur16Proteinuria QTL 1617.2urine total protein amount (VT:0000032)urine protein level (CMO:0000591)133615572341961389Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13142356786Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat

Markers in Region
D13Mgh4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,415,584 - 37,415,726 (+)MAPPERmRatBN7.2
Rnor_6.01342,310,744 - 42,310,885NCBIRnor6.0
Rnor_5.01347,416,073 - 47,416,214UniSTSRnor5.0
RGSC_v3.41338,489,801 - 38,489,943RGDRGSC3.4
RGSC_v3.41338,489,802 - 38,489,943UniSTSRGSC3.4
RGSC_v3.11338,503,844 - 38,503,986RGD
Celera1337,210,510 - 37,210,651UniSTS
RH 2.0 Map13248.6RGD
SHRSP x BN Map137.9399RGD
FHH x ACI Map139.21RGD
Cytogenetic Map13q11UniSTS
D13Rat38  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,658,659 - 37,658,786 (+)MAPPERmRatBN7.2
Rnor_6.01342,552,414 - 42,552,540NCBIRnor6.0
Rnor_5.01347,657,736 - 47,657,862UniSTSRnor5.0
RGSC_v3.41338,741,256 - 38,741,500RGDRGSC3.4
RGSC_v3.41338,741,276 - 38,741,402UniSTSRGSC3.4
RGSC_v3.11338,755,299 - 38,755,543RGD
Celera1337,446,859 - 37,447,001UniSTS
RH 2.0 Map13224.5RGD
FHH x ACI Map139.21RGD
Cytogenetic Map13q11UniSTS
D13Rat80  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21338,016,571 - 38,016,830 (+)MAPPERmRatBN7.2
Rnor_6.01342,907,543 - 42,907,801NCBIRnor6.0
Rnor_5.01348,011,004 - 48,011,262UniSTSRnor5.0
RGSC_v3.41339,111,048 - 39,111,307RGDRGSC3.4
RGSC_v3.41339,111,049 - 39,111,307UniSTSRGSC3.4
RGSC_v3.11339,125,091 - 39,125,350RGD
Celera1338,683,274 - 38,683,533UniSTS
SHRSP x BN Map138.0099UniSTS
SHRSP x BN Map138.0099RGD
FHH x ACI Map139.21RGD
Cytogenetic Map13q11UniSTS
D13Arb5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,902,608 - 37,902,821 (-)MAPPERmRatBN7.2
mRatBN7.21337,902,608 - 37,902,821 (+)MAPPERmRatBN7.2
Rnor_6.01343,785,727 - 43,785,939NCBIRnor6.0
Rnor_6.01342,794,724 - 42,794,936NCBIRnor6.0
Rnor_5.01348,881,057 - 48,881,269UniSTSRnor5.0
Rnor_5.01347,898,759 - 47,898,971UniSTSRnor5.0
RGSC_v3.41338,985,717 - 38,985,930RGDRGSC3.4
RGSC_v3.41338,985,718 - 38,985,930UniSTSRGSC3.4
RGSC_v3.11338,999,761 - 38,999,973RGD
Celera1337,690,125 - 37,690,337UniSTS
RH 3.4 Map1375.6UniSTS
RH 3.4 Map1375.6RGD
SHRSP x BN Map137.9399RGD
SHRSP x BN Map137.9399UniSTS
FHH x ACI Map138.9999RGD
Cytogenetic Map13q11UniSTS
D13Arb6  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01343,013,004 - 43,013,161NCBIRnor6.0
Rnor_5.01348,115,263 - 48,115,420UniSTSRnor5.0
RGSC_v3.41339,222,634 - 39,222,811RGDRGSC3.4
RGSC_v3.41339,222,635 - 39,222,811UniSTSRGSC3.4
RGSC_v3.11339,236,677 - 39,236,854RGD
Celera1338,756,917 - 38,757,093UniSTS
FHH x ACI Map139.35UniSTS
FHH x ACI Map139.35RGD
Cytogenetic Map13q11UniSTS
D13Got6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,386,362 - 37,386,542 (+)MAPPERmRatBN7.2
Rnor_6.01342,281,442 - 42,281,621NCBIRnor6.0
Rnor_5.01347,386,650 - 47,386,829UniSTSRnor5.0
RGSC_v3.41338,459,370 - 38,459,550RGDRGSC3.4
RGSC_v3.41338,459,371 - 38,459,550UniSTSRGSC3.4
RGSC_v3.11338,473,413 - 38,473,593RGD
RH 2.0 Map13219.3RGD
Cytogenetic Map13q11UniSTS
D13Got12  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01342,944,498 - 42,944,692NCBIRnor6.0
Rnor_5.01348,046,593 - 48,046,787UniSTSRnor5.0
RGSC_v3.41339,147,206 - 39,147,505RGDRGSC3.4
RGSC_v3.41339,147,207 - 39,147,505UniSTSRGSC3.4
RGSC_v3.11339,161,249 - 39,161,548RGD
Celera1338,648,875 - 38,649,173UniSTS
RH 2.0 Map13229.1RGD
Cytogenetic Map13q11UniSTS
D13Got9  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,902,606 - 37,902,855 (+)MAPPERmRatBN7.2
mRatBN7.21337,902,606 - 37,902,855 (-)MAPPERmRatBN7.2
Rnor_6.01343,785,693 - 43,785,941NCBIRnor6.0
Rnor_6.01342,794,722 - 42,794,970NCBIRnor6.0
Rnor_5.01347,898,757 - 47,899,005UniSTSRnor5.0
Rnor_5.01348,881,023 - 48,881,271UniSTSRnor5.0
RGSC_v3.41338,985,716 - 38,985,964UniSTSRGSC3.4
RGSC_v3.41338,985,715 - 38,985,964RGDRGSC3.4
RGSC_v3.11338,999,759 - 39,000,007RGD
Celera1337,690,123 - 37,690,371UniSTS
RH 3.4 Map1374.3UniSTS
RH 3.4 Map1374.3RGD
RH 2.0 Map13230.1RGD
Cytogenetic Map13q11UniSTS
D13Got10  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,877,282 - 37,877,427 (+)MAPPERmRatBN7.2
Rnor_6.01342,770,243 - 42,770,387NCBIRnor6.0
Rnor_5.01347,874,507 - 47,874,651UniSTSRnor5.0
RGSC_v3.41338,961,078 - 38,961,223RGDRGSC3.4
RGSC_v3.41338,961,079 - 38,961,223UniSTSRGSC3.4
RGSC_v3.11338,975,121 - 38,975,266RGD
Celera1337,665,923 - 37,666,067UniSTS
RH 2.0 Map13231.6RGD
Cytogenetic Map13q11UniSTS
D13Uwm6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,970,583 - 37,970,825 (+)MAPPERmRatBN7.2
mRatBN7.21337,970,583 - 37,970,825 (-)MAPPERmRatBN7.2
Rnor_6.01343,717,605 - 43,717,846NCBIRnor6.0
Rnor_6.01342,861,715 - 42,861,956NCBIRnor6.0
Rnor_5.01347,965,750 - 47,965,991UniSTSRnor5.0
Rnor_5.01348,813,685 - 48,813,926UniSTSRnor5.0
RGSC_v3.41339,055,043 - 39,055,284UniSTSRGSC3.4
RGSC_v3.11339,069,085 - 39,069,327RGD
Celera1338,728,176 - 38,728,417UniSTS
Cytogenetic Map13q11UniSTS
D13Hmgc60  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,954,050 - 37,954,174 (+)MAPPERmRatBN7.2
mRatBN7.21337,954,050 - 37,954,174 (-)MAPPERmRatBN7.2
Rnor_6.01342,846,517 - 42,846,640NCBIRnor6.0
Rnor_6.01343,734,239 - 43,734,362NCBIRnor6.0
Rnor_5.01348,829,963 - 48,830,086UniSTSRnor5.0
Rnor_5.01347,950,552 - 47,950,675UniSTSRnor5.0
RGSC_v3.41339,038,836 - 39,038,959UniSTSRGSC3.4
Celera1338,744,628 - 38,744,751UniSTS
Cytogenetic Map13q11UniSTS
D13Hmgc72  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,585,892 - 37,586,087 (+)MAPPERmRatBN7.2
Rnor_6.01342,479,728 - 42,479,922NCBIRnor6.0
Rnor_5.01347,585,011 - 47,585,205UniSTSRnor5.0
Celera1337,374,275 - 37,374,494UniSTS
Cytogenetic Map13q11UniSTS
D13Hmgc93  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,406,467 - 37,406,640 (+)MAPPERmRatBN7.2
Rnor_6.01342,301,732 - 42,301,904NCBIRnor6.0
Rnor_5.01347,407,061 - 47,407,233UniSTSRnor5.0
Celera1337,201,381 - 37,201,545UniSTS
Cytogenetic Map13q11UniSTS
AU050004  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,550,806 - 37,550,920 (+)MAPPERmRatBN7.2
Rnor_6.01342,444,642 - 42,444,755NCBIRnor6.0
Rnor_5.01347,549,925 - 47,550,038UniSTSRnor5.0
RGSC_v3.41338,633,034 - 38,633,147UniSTSRGSC3.4
Celera1337,339,214 - 37,339,327UniSTS
Cytogenetic Map13q11UniSTS
AU048264  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,383,669 - 37,383,805 (+)MAPPERmRatBN7.2
Rnor_6.01342,278,749 - 42,278,884NCBIRnor6.0
Rnor_5.01347,383,957 - 47,384,092UniSTSRnor5.0
RGSC_v3.41338,456,678 - 38,456,813UniSTSRGSC3.4
Celera1337,178,641 - 37,178,776UniSTS
Cytogenetic Map13q11UniSTS
AU048115  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,775,559 - 37,775,722 (+)MAPPERmRatBN7.2
Rnor_6.01342,668,593 - 42,668,755NCBIRnor6.0
Rnor_5.01347,772,856 - 47,773,018UniSTSRnor5.0
RGSC_v3.41338,859,302 - 38,859,464UniSTSRGSC3.4
Celera1337,564,195 - 37,564,357UniSTS
Cytogenetic Map13q11UniSTS
AU047140  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,414,221 - 37,414,349 (+)MAPPERmRatBN7.2
Rnor_6.01342,309,384 - 42,309,508NCBIRnor6.0
Rnor_5.01347,414,713 - 47,414,837UniSTSRnor5.0
RGSC_v3.41338,488,439 - 38,488,565UniSTSRGSC3.4
Celera1337,209,145 - 37,209,274UniSTS
Cytogenetic Map13q11UniSTS
AU048869  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21337,887,947 - 37,888,081 (+)MAPPERmRatBN7.2
Rnor_6.01342,780,913 - 42,781,044NCBIRnor6.0
Rnor_5.01347,884,948 - 47,885,079UniSTSRnor5.0
RGSC_v3.41338,972,216 - 38,972,347UniSTSRGSC3.4
Celera1337,676,423 - 37,676,554UniSTS
Cytogenetic Map13q11UniSTS


Genetic Models
This gene Nckap5 is modified in the following models/strains:
SS-Nckap5em2Mcwi     SS-Nckap5em1Mcwi     SS-Nckap5em3Mcwi     SS-Nckap5em3Mcwi-/-     SS-Nckap5em1Mcwi-/-     SS-Nckap5em2Mcwi-/-     SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi    


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 20 5 11
Low 2 41 51 38 8 38 1 1 54 35 36 1
Below cutoff 1 2 4 3 11 3 7 9 7

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008761432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000038020   ⟹   ENSRNOP00000029665
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1337,370,792 - 38,203,753 (-)Ensembl
Rnor_6.0 Ensembl1342,265,806 - 42,885,440 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100167   ⟹   ENSRNOP00000080373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1337,371,369 - 38,283,268 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105224   ⟹   ENSRNOP00000085272
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1337,371,278 - 38,283,268 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116447   ⟹   ENSRNOP00000084549
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1337,370,792 - 38,203,753 (-)Ensembl
RefSeq Acc Id: XM_008769508   ⟹   XP_008767730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,494,108 (-)NCBI
mRatBN7.21337,369,948 - 37,938,839 (-)NCBI
Rnor_6.01342,265,875 - 42,808,034 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599036   ⟹   XP_017454525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,494,109 (-)NCBI
mRatBN7.21337,369,948 - 37,938,840 (-)NCBI
Rnor_6.01342,265,875 - 42,808,034 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599038   ⟹   XP_017454527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,923,987 - 40,494,110 (-)NCBI
mRatBN7.21337,371,256 - 37,938,841 (-)NCBI
Rnor_6.01342,266,389 - 42,808,034 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599040   ⟹   XP_017454529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,835,849 (-)NCBI
mRatBN7.21337,369,948 - 38,283,257 (-)NCBI
Rnor_6.01342,265,875 - 43,049,232 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039091162   ⟹   XP_038947090
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,756,188 (-)NCBI
mRatBN7.21337,369,948 - 38,203,614 (-)NCBI
RefSeq Acc Id: XM_039091163   ⟹   XP_038947091
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,626,680 (-)NCBI
mRatBN7.21337,369,948 - 38,074,074 (-)NCBI
RefSeq Acc Id: XM_039091164   ⟹   XP_038947092
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,505,746 (-)NCBI
mRatBN7.21337,369,948 - 37,953,134 (-)NCBI
RefSeq Acc Id: XM_039091165   ⟹   XP_038947093
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,489,586 (-)NCBI
mRatBN7.21337,369,948 - 37,937,002 (-)NCBI
RefSeq Acc Id: XM_039091166   ⟹   XP_038947094
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,513,945 (-)NCBI
mRatBN7.21337,369,948 - 37,961,360 (-)NCBI
RefSeq Acc Id: XM_039091168   ⟹   XP_038947096
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,360,157 (-)NCBI
mRatBN7.21337,369,948 - 37,807,559 (-)NCBI
RefSeq Acc Id: XM_039091169   ⟹   XP_038947097
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,835,849 (-)NCBI
mRatBN7.21337,369,948 - 38,283,257 (-)NCBI
RefSeq Acc Id: XM_063272672   ⟹   XP_063128742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,626,680 (-)NCBI
RefSeq Acc Id: XM_063272673   ⟹   XP_063128743
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,547,311 (-)NCBI
RefSeq Acc Id: XM_063272674   ⟹   XP_063128744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,626,680 (-)NCBI
RefSeq Acc Id: XM_063272675   ⟹   XP_063128745
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,547,334 (-)NCBI
RefSeq Acc Id: XM_063272676   ⟹   XP_063128746
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81339,922,576 - 40,494,112 (-)NCBI
RefSeq Acc Id: XP_008767730   ⟸   XM_008769508
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZYD4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454529   ⟸   XM_017599040
- Peptide Label: isoform X2
- UniProtKB: F1LU96 (UniProtKB/TrEMBL),   A0A8I5ZYD4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454525   ⟸   XM_017599036
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZYD4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454527   ⟸   XM_017599038
- Peptide Label: isoform X7
- UniProtKB: A0A8I6A100 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000029665   ⟸   ENSRNOT00000038020
RefSeq Acc Id: XP_038947097   ⟸   XM_039091169
- Peptide Label: isoform X12
- UniProtKB: A0A8I5ZYD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947090   ⟸   XM_039091162
- Peptide Label: isoform X2
- UniProtKB: F1LU96 (UniProtKB/TrEMBL),   A0A8I5ZYD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947091   ⟸   XM_039091163
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZYD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947094   ⟸   XM_039091166
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZYD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947092   ⟸   XM_039091164
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZYD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947093   ⟸   XM_039091165
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZYD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947096   ⟸   XM_039091168
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZYD4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000084549   ⟸   ENSRNOT00000116447
Ensembl Acc Id: ENSRNOP00000085272   ⟸   ENSRNOT00000105224
Ensembl Acc Id: ENSRNOP00000080373   ⟸   ENSRNOT00000100167
RefSeq Acc Id: XP_063128742   ⟸   XM_063272672
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZYD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128744   ⟸   XM_063272674
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZYD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128745   ⟸   XM_063272675
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZYD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128743   ⟸   XM_063272673
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZYD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128746   ⟸   XM_063272676
- Peptide Label: isoform X11
- UniProtKB: A0A8I6A100 (UniProtKB/TrEMBL)
Protein Domains
Nck-associated protein 5 C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LU96-F1-model_v2 AlphaFold F1LU96 1-1811 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564507 AgrOrtholog
BioCyc Gene G2FUF-18450 BioCyc
Ensembl Genes ENSRNOG00000021553 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038020.7 UniProtKB/TrEMBL
  ENSRNOT00000100167.1 UniProtKB/TrEMBL
  ENSRNOT00000105224.1 UniProtKB/TrEMBL
  ENSRNOT00000116447.1 UniProtKB/TrEMBL
InterPro NCKAP5_C UniProtKB/TrEMBL
  Nckap5l UniProtKB/TrEMBL
NCBI Gene 363974 ENTREZGENE
PANTHER NCK-ASSOCIATED PROTEIN 5 UniProtKB/TrEMBL
  PTHR21740 UniProtKB/TrEMBL
Pfam NCKAP5 UniProtKB/TrEMBL
PhenoGen Nckap5 PhenoGen
RatGTEx ENSRNOG00000021553 RatGTEx
UniProt A0A8I5ZPN2_RAT UniProtKB/TrEMBL
  A0A8I5ZYD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A100 ENTREZGENE, UniProtKB/TrEMBL
  F1LU96 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-06-16 Nap5  Nck-associated protein 5  RGD1564507  similar to Nck-associated protein 5   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1564507  similar to Nck-associated protein 5   RGD1564507_predicted  similar to Nck-associated protein 5 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564507_predicted  similar to Nck-associated protein 5 (predicted)  LOC363974  similar to Nck-associated protein 5  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC363974  similar to Nck-associated protein 5      Symbol and Name status set to provisional 70820 PROVISIONAL