Cntn2 (contactin 2) - Rat Genome Database

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Gene: Cntn2 (contactin 2) Rattus norvegicus
Analyze
Symbol: Cntn2
Name: contactin 2
RGD ID: 3821
Description: Predicted to enable carbohydrate binding activity and cell-cell adhesion mediator activity. Involved in axonogenesis and cell-matrix adhesion. Located in plasma membrane and synapse. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 5. Orthologous to human CNTN2 (contactin 2); INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: axonal glycoprotein TAG-1; axonin-1; contactin 2 (axonal); contactin-2; TAG-1; TAG-564; TAG1; Tax; TAX-1; transient axonal glycoprotein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81346,497,269 - 46,528,112 (-)NCBIGRCr8
mRatBN7.21343,942,868 - 43,975,973 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1343,947,265 - 43,975,887 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1346,554,249 - 46,582,887 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01347,842,379 - 47,871,008 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01345,103,086 - 45,131,717 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01349,280,913 - 49,314,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1349,285,310 - 49,313,940 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01354,356,315 - 54,389,667 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41345,399,915 - 45,428,789 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11345,413,957 - 45,442,832 (-)NCBI
Celera1344,281,845 - 44,310,387 (-)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
alpha-amanitin  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
Brodifacoum  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (EXP)
chlorpyrifos  (ISO)
copper(II) sulfate  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
folic acid  (ISO)
glyphosate  (EXP,ISO)
lead(0)  (ISO)
Licochalcone B  (ISO)
mercury dibromide  (ISO)
methamphetamine  (EXP)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
PCB138  (ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sevoflurane  (EXP,ISO)
sodium arsenite  (ISO)
Tetrachlorobisphenol A  (ISO)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
triazines  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
venlafaxine hydrochloride  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Nr-CAM and TAG-1 are expressed in distinct populations of developing precerebellar and cerebellar neurons. Backer S, etal., Neuroscience 2002;113(4):743-8.
2. Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders. Bakkaloglu B, etal., Am J Hum Genet. 2008 Jan;82(1):165-73. doi: 10.1016/j.ajhg.2007.09.017.
3. The axonal glycoprotein TAG-1 is an immunoglobulin superfamily member with neurite outgrowth-promoting activity. Furley AJ, etal., Cell 1990 Apr 6;61(1):157-70.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Increased expression of HBZ and Foxp3 mRNA in bronchoalveolar lavage cells taken from human T-lymphotropic virus type 1-associated lung disorder patients. Nakayama Y, etal., Intern Med. 2013;52(23):2599-609. doi: 10.2169/internalmedicine.52.0845.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. The gene for the axonal cell adhesion molecule TAX-1 is amplified and aberrantly expressed in malignant gliomas. Rickman DS, etal., Cancer Res 2001 Mar 1;61(5):2162-8.
13. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
14. The neuronal adhesion protein TAG-1 is expressed by Schwann cells and oligodendrocytes and is localized to the juxtaparanodal region of myelinated fibers. Traka M, etal., J Neurosci 2002 Apr 15;22(8):3016-24.
Additional References at PubMed
PMID:8089271   PMID:11178983   PMID:11714688   PMID:11807022   PMID:12950086   PMID:12963709   PMID:12975355   PMID:15964824   PMID:16225856   PMID:16701205   PMID:17086203   PMID:18278038  
PMID:18550718   PMID:18650339   PMID:18760366   PMID:19109503   PMID:19416878   PMID:19458237   PMID:20962216   PMID:23518707   PMID:26217189   PMID:26722394   PMID:30078168   PMID:33044326  


Genomics

Comparative Map Data
Cntn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81346,497,269 - 46,528,112 (-)NCBIGRCr8
mRatBN7.21343,942,868 - 43,975,973 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1343,947,265 - 43,975,887 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1346,554,249 - 46,582,887 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01347,842,379 - 47,871,008 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01345,103,086 - 45,131,717 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01349,280,913 - 49,314,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1349,285,310 - 49,313,940 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01354,356,315 - 54,389,667 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41345,399,915 - 45,428,789 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11345,413,957 - 45,442,832 (-)NCBI
Celera1344,281,845 - 44,310,387 (-)NCBICelera
Cytogenetic Map13q13NCBI
CNTN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381205,042,949 - 205,078,289 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1205,042,937 - 205,078,289 (+)EnsemblGRCh38hg38GRCh38
GRCh371205,012,077 - 205,047,417 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361203,278,963 - 203,313,761 (+)NCBINCBI36Build 36hg18NCBI36
Build 341201,743,996 - 201,778,793NCBI
Celera1178,147,407 - 178,182,200 (+)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1176,177,847 - 176,212,673 (+)NCBIHuRef
CHM1_11206,435,687 - 206,470,502 (+)NCBICHM1_1
T2T-CHM13v2.01204,307,317 - 204,342,659 (+)NCBIT2T-CHM13v2.0
Cntn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,437,163 - 132,470,989 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,437,165 - 132,470,994 (-)EnsemblGRCm39 Ensembl
GRCm381132,509,425 - 132,543,251 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,509,427 - 132,543,256 (-)EnsemblGRCm38mm10GRCm38
MGSCv371134,406,002 - 134,439,517 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361134,336,973 - 134,370,462 (-)NCBIMGSCv36mm8
Celera1135,118,092 - 135,152,003 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map157.42NCBI
Cntn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540640,831,850 - 40,858,569 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540640,831,897 - 40,862,445 (+)NCBIChiLan1.0ChiLan1.0
CNTN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2144,298,727 - 44,333,562 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1144,264,002 - 44,298,806 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01180,645,259 - 180,680,081 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11184,931,902 - 184,966,482 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1184,931,497 - 184,966,482 (+)Ensemblpanpan1.1panPan2
CNTN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1381,570,598 - 1,600,524 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl381,576,898 - 1,596,621 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha381,661,917 - 1,694,727 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0381,564,191 - 1,597,016 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl381,563,948 - 1,596,983 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1381,560,461 - 1,593,270 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0381,951,695 - 1,980,625 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0382,151,770 - 2,184,597 (+)NCBIUU_Cfam_GSD_1.0
Cntn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934470,057,146 - 70,080,384 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365577,297,422 - 7,320,846 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365577,297,429 - 7,320,666 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNTN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl965,736,740 - 65,776,396 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1965,737,488 - 65,776,412 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CNTN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12524,262,092 - 24,296,740 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2524,261,651 - 24,296,850 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605525,018,404 - 25,053,686 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cntn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248076,056,339 - 6,073,588 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248076,052,591 - 6,080,421 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:293
Count of miRNA genes:170
Interacting mature miRNAs:214
Transcripts:ENSRNOT00000012190
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131186625456866254Rat
6893344Cm79Cardiac mass QTL 791.50.04heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)134627292251216694Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131244842147969993Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131746828262468282Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13600200847359539Rat
2303032Bp328Blood pressure QTL 328arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134373632747969993Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132433543255601132Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131244842148744906Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
4145117Mcs27Mammary carcinoma susceptibility QTL 270.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)134599007750392939Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133379409660914504Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131771133662711336Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131186625456866254Rat

Markers in Region
RH142422  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21343,959,548 - 43,960,824 (+)MAPPERmRatBN7.2
Rnor_6.01349,297,603 - 49,298,877NCBIRnor6.0
Rnor_5.01354,373,249 - 54,374,523UniSTSRnor5.0
RGSC_v3.41345,412,454 - 45,413,728UniSTSRGSC3.4
Celera1344,294,052 - 44,295,326UniSTS
Cytogenetic Map13q13UniSTS
AW528446  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21343,947,330 - 43,947,474 (+)MAPPERmRatBN7.2
Rnor_6.01349,285,376 - 49,285,519NCBIRnor6.0
Rnor_5.01354,360,776 - 54,360,919UniSTSRnor5.0
RGSC_v3.41345,399,981 - 45,400,124UniSTSRGSC3.4
Celera1344,281,911 - 44,282,054UniSTS
Cytogenetic Map13q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 64 63 32 24 32 6 190 96 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000012190   ⟹   ENSRNOP00000012190
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1343,947,265 - 43,975,887 (-)Ensembl
Rnor_6.0 Ensembl1349,285,310 - 49,313,940 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109604   ⟹   ENSRNOP00000076834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1343,947,265 - 43,962,830 (-)Ensembl
RefSeq Acc Id: NM_012884   ⟹   NP_037016
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81346,499,396 - 46,528,025 (-)NCBI
mRatBN7.21343,947,265 - 43,975,885 (-)NCBI
Rnor_6.01349,285,310 - 49,313,938 (-)NCBI
Rnor_5.01354,356,315 - 54,389,667 (-)NCBI
RGSC_v3.41345,399,915 - 45,428,789 (-)RGD
Celera1344,281,845 - 44,310,387 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249746   ⟹   XP_006249808
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81346,497,269 - 46,528,110 (-)NCBI
mRatBN7.21343,942,868 - 43,975,972 (-)NCBI
Rnor_6.01349,280,913 - 49,314,061 (-)NCBI
Rnor_5.01354,356,315 - 54,389,667 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039090383   ⟹   XP_038946311
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81346,497,269 - 46,528,112 (-)NCBI
mRatBN7.21343,942,868 - 43,975,973 (-)NCBI
RefSeq Acc Id: XR_010056901
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81346,497,269 - 46,528,110 (-)NCBI
Protein Sequences
Protein RefSeqs NP_037016 (Get FASTA)   NCBI Sequence Viewer  
  XP_006249808 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946311 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA42201 (Get FASTA)   NCBI Sequence Viewer  
  EDM09793 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012190.2
  ENSRNOP00000076834.1
GenBank Protein P22063 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_037016   ⟸   NM_012884
- Peptide Label: precursor
- UniProtKB: P22063 (UniProtKB/Swiss-Prot),   G3V758 (UniProtKB/TrEMBL),   A6IC54 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249808   ⟸   XM_006249746
- Peptide Label: isoform X1
- UniProtKB: P22063 (UniProtKB/Swiss-Prot),   G3V758 (UniProtKB/TrEMBL),   A6IC54 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012190   ⟸   ENSRNOT00000012190
RefSeq Acc Id: XP_038946311   ⟸   XM_039090383
- Peptide Label: isoform X2
- UniProtKB: P22063 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000076834   ⟸   ENSRNOT00000109604
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P22063-F1-model_v2 AlphaFold P22063 1-1040 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698816
Promoter ID:EPDNEW_R9339
Type:single initiation site
Name:Cntn2_1
Description:contactin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01349,313,950 - 49,314,010EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3821 AgrOrtholog
BioCyc Gene G2FUF-18313 BioCyc
Ensembl Genes ENSRNOG00000009033 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012190.4 UniProtKB/TrEMBL
  ENSRNOT00000109604.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Contactin-1_2_Ig1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25356 UniProtKB/Swiss-Prot
NCBI Gene 25356 ENTREZGENE
PANTHER CONTACTIN-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN SIDEKICK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam fn3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cntn2 PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009033 RatGTEx
SMART FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC232614
UniProt A0A8I5ZJA8_RAT UniProtKB/TrEMBL
  A6IC54 ENTREZGENE, UniProtKB/TrEMBL
  CNTN2_RAT UniProtKB/Swiss-Prot
  G3V758 ENTREZGENE, UniProtKB/TrEMBL
  P22063 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-16 Cntn2  contactin 2  Cntn2  contactin 2 (axonal)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Cntn2  contactin 2 (axonal)  Cntn2  contactin 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2001-11-29 Cntn2  Contactin 2      Symbol and Name updated to reflect Human and Mouse nomenclature 68913 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed by Schwann cells and oligodendrocytes 625462